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4-Bromo-1-Chloro-2-(Chloromethyl)Benzene
Linshang Chemical
|
HS Code |
291901 |
| Chemical Formula | C7H5BrCl2 |
| Molecular Weight | 223.92 |
| Appearance | Solid (Typical) |
| Odor | Characteristic aromatic odor |
| Melting Point | Data may vary, needs experimental determination |
| Boiling Point | Data may vary, needs experimental determination |
| Solubility In Water | Low solubility |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Density | Data may vary, needs experimental determination |
| Stability | Stable under normal conditions, but reactive to strong oxidizing agents |
As an accredited 4-Bromo-1-Chloro-2-(Chloromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 4 - bromo - 1 - chloro - 2-(chloromethyl)benzene in a sealed, labeled bottle. |
| Storage | 4 - bromo - 1 - chloro - 2 - (chloromethyl)benzene should be stored in a cool, dry, well - ventilated area away from heat sources, ignition sources, and oxidizing agents. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass. Label the container clearly to prevent misidentification. Store it separately from incompatible substances to avoid potential reactions. |
| Shipping | 4 - bromo - 1 - chloro - 2 - (chloromethyl)benzene is shipped in sealed, corrosion - resistant containers. Special care is taken to prevent leakage during transit, following strict chemical transportation regulations to ensure safety. |
Competitive 4-Bromo-1-Chloro-2-(Chloromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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What is the Chinese name of 4-bromo-1-chloro-2- (chloromethyl) benzene?
4-Bromo-1-chloro-2 - (chloromethyl) benzene, this is the name of an organic compound. According to the organic nomenclature, first determine the main chain or parent, this is the benzene ring; then look at the substituent, bromine, chlorine and chloromethyl are the substituents. With the benzene ring as the parent, the number of substituents is positioned to reach the minimum sum of the substituent positions. In this compound, bromine is attached to the benzene ring at position 4, chlorine at position 1, and chloromethyl at position 2, so it is named 4-bromo-1-chloro-2 - (chloromethyl) benzene. This nomenclature is accurate and can accurately describe the structure of the compound in the field of organic chemistry, which is convenient for scholars to exchange and discuss, and is of great significance to the work of organic synthesis and property exploration.
What are the physical properties of 4-bromo-1-chloro-2- (chloromethyl) benzene?
4-Bromo-1-chloro-2- (chloromethyl) benzene is also an organic compound. Its physical properties are particularly important, related to the use and properties of this substance.
Looking at its properties, under normal temperature and pressure, it is mostly a colorless to light yellow liquid, or a crystalline solid, depending on its specific conditions. Its melting point and boiling point have fixed numbers, the melting point is about [X] ° C, and the boiling point is about [X] ° C. These two are key parameters in chemical preparation, separation and purification. If you want to obtain a pure product, according to its melting and boiling point, you can choose the method of distillation and recrystallization to remove impurities and store them in the main product.
Furthermore, the density of this substance is also important. Its density is about [X] g/cm ³, which is heavier or lighter than water, depending on its distribution in the liquid-liquid system. In some reactions or extraction processes, the density difference can make it stratified with other substances for the purpose of separation.
In terms of solubility, 4-bromo-1-chloro-2 - (chloromethyl) benzene is insoluble in water, but soluble in many organic solvents, such as ethanol, ether, dichloromethane, etc. This solubility property is widely used in organic synthesis reactions. Due to the fact that many organic reactions need to be carried out smoothly in a homogeneous system, this substance can be fully mixed with the reactants with the help of organic solvents to promote the speed of the reaction and increase the effect of the reaction.
Volatility is also one end of its physical properties. Although its volatility is not very high, it will still be partially volatilized when exposed to the environment or heated. This property should be paid attention to when storing and using. When sealed in a cool place, it should be stored to prevent its volatilization from escaping and causing damage to the environment.
In summary, the physical properties of 4-bromo-1-chloro-2- (chloromethyl) benzene, such as their properties, melting point, density, solubility, and volatility, are of great significance in chemical production, organic synthesis, and storage.
Looking at its properties, under normal temperature and pressure, it is mostly a colorless to light yellow liquid, or a crystalline solid, depending on its specific conditions. Its melting point and boiling point have fixed numbers, the melting point is about [X] ° C, and the boiling point is about [X] ° C. These two are key parameters in chemical preparation, separation and purification. If you want to obtain a pure product, according to its melting and boiling point, you can choose the method of distillation and recrystallization to remove impurities and store them in the main product.
Furthermore, the density of this substance is also important. Its density is about [X] g/cm ³, which is heavier or lighter than water, depending on its distribution in the liquid-liquid system. In some reactions or extraction processes, the density difference can make it stratified with other substances for the purpose of separation.
In terms of solubility, 4-bromo-1-chloro-2 - (chloromethyl) benzene is insoluble in water, but soluble in many organic solvents, such as ethanol, ether, dichloromethane, etc. This solubility property is widely used in organic synthesis reactions. Due to the fact that many organic reactions need to be carried out smoothly in a homogeneous system, this substance can be fully mixed with the reactants with the help of organic solvents to promote the speed of the reaction and increase the effect of the reaction.
Volatility is also one end of its physical properties. Although its volatility is not very high, it will still be partially volatilized when exposed to the environment or heated. This property should be paid attention to when storing and using. When sealed in a cool place, it should be stored to prevent its volatilization from escaping and causing damage to the environment.
In summary, the physical properties of 4-bromo-1-chloro-2- (chloromethyl) benzene, such as their properties, melting point, density, solubility, and volatility, are of great significance in chemical production, organic synthesis, and storage.
What are the chemical properties of 4-bromo-1-chloro-2- (chloromethyl) benzene?
4-Bromo-1-chloro-2- (chloromethyl) benzene, this is an organic compound, its chemical properties are particularly critical, and it is of great significance to many chemical processes and practical applications.
First describes its halogenated hydrocarbon properties. Intramolecular bromine atoms, chlorine atoms and chloromethyl atoms all endow it with active reactivity. In nucleophilic substitution reactions, bromine and chlorine atoms can be replaced by nucleophiles. For example, when encountering hydroxyl negative ions (OH), substitution can occur, and bromine or chlorine atoms leave, and hydroxyl groups are connected to form benzene derivatives containing hydroxyl groups. This reaction is often used in organic synthesis to construct new functional groups and lay the foundation for the preparation of various organic compounds.
Chloromethyl is also active. In a strong alkali environment, it is easy to initiate elimination reactions, remove hydrogen chloride, and form unsaturated bonds. Or nucleophilic substitution occurs with nucleophiles, and chlorine atoms are replaced to realize functional group transformation.
Furthermore, the benzene ring conjugate system has a deep impact on its properties. Due to the stability of the benzene ring, the compound is relatively stable as a whole, but the electron cloud density distribution on the benzene ring is affected by halogen atoms and chloromethyl. Halogen atoms and chloromethyl groups are electron-absorbing groups, which will reduce the electron cloud density of the benzene ring and reduce the activity of the electrophilic substitution reaction of the benzene ring. However, under certain conditions, electrophilic substitution can still occur, such as bromine reaction catalyzed by iron bromide, which can introduce bromine atoms at specific
In addition, the compound has a certain solubility. Because it is an organic compound, it has good solubility in common organic solvents such as ethanol, ether, and dichloromethane, but poor solubility in water. This solubility characteristic is crucial in separation, purification, and solvent selection.
4-Bromo-1-chloro-2 - (chloromethyl) benzene has rich chemical properties and has potential applications in organic synthesis, medicinal chemistry, materials science, and other fields. It is relied on by chemical research and industrial production.
First describes its halogenated hydrocarbon properties. Intramolecular bromine atoms, chlorine atoms and chloromethyl atoms all endow it with active reactivity. In nucleophilic substitution reactions, bromine and chlorine atoms can be replaced by nucleophiles. For example, when encountering hydroxyl negative ions (OH), substitution can occur, and bromine or chlorine atoms leave, and hydroxyl groups are connected to form benzene derivatives containing hydroxyl groups. This reaction is often used in organic synthesis to construct new functional groups and lay the foundation for the preparation of various organic compounds.
Chloromethyl is also active. In a strong alkali environment, it is easy to initiate elimination reactions, remove hydrogen chloride, and form unsaturated bonds. Or nucleophilic substitution occurs with nucleophiles, and chlorine atoms are replaced to realize functional group transformation.
Furthermore, the benzene ring conjugate system has a deep impact on its properties. Due to the stability of the benzene ring, the compound is relatively stable as a whole, but the electron cloud density distribution on the benzene ring is affected by halogen atoms and chloromethyl. Halogen atoms and chloromethyl groups are electron-absorbing groups, which will reduce the electron cloud density of the benzene ring and reduce the activity of the electrophilic substitution reaction of the benzene ring. However, under certain conditions, electrophilic substitution can still occur, such as bromine reaction catalyzed by iron bromide, which can introduce bromine atoms at specific
In addition, the compound has a certain solubility. Because it is an organic compound, it has good solubility in common organic solvents such as ethanol, ether, and dichloromethane, but poor solubility in water. This solubility characteristic is crucial in separation, purification, and solvent selection.
4-Bromo-1-chloro-2 - (chloromethyl) benzene has rich chemical properties and has potential applications in organic synthesis, medicinal chemistry, materials science, and other fields. It is relied on by chemical research and industrial production.
What are the main uses of 4-bromo-1-chloro-2- (chloromethyl) benzene?
4-Bromo-1-chloro-2- (chloromethyl) benzene, this is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
Viewing its structure, the presence of bromine, chlorine atoms and chloromethyl groups endows the compound with unique reactivity. With its activity, more complex organic molecular structures can be constructed through various chemical reactions, such as nucleophilic substitution reactions.
In the field of medicinal chemistry, or an important starting material for the synthesis of new drugs. Due to the introduction of halogen atoms such as bromine and chlorine, the physical and chemical properties of drug molecules, such as fat solubility and stability, can be adjusted, which in turn affects the biological activity of drugs and the metabolic process in vivo.
It also has potential applications in materials science. Through subsequent reactions, it can be integrated into polymer materials to give materials special properties, such as flame retardancy. Because halogen atoms can play a certain flame retardant role in the combustion process.
Furthermore, in the field of pesticides, pesticide products with high insecticidal, bactericidal or herbicidal activities can be created through rational derivatization.
In conclusion, 4-bromo-1-chloro-2 - (chloromethyl) benzene has shown important application value in many fields such as organic synthesis, drugs, materials, and pesticides due to its unique structure and reactivity, providing an indispensable material basis for the development of many chemical-related industries.
Viewing its structure, the presence of bromine, chlorine atoms and chloromethyl groups endows the compound with unique reactivity. With its activity, more complex organic molecular structures can be constructed through various chemical reactions, such as nucleophilic substitution reactions.
In the field of medicinal chemistry, or an important starting material for the synthesis of new drugs. Due to the introduction of halogen atoms such as bromine and chlorine, the physical and chemical properties of drug molecules, such as fat solubility and stability, can be adjusted, which in turn affects the biological activity of drugs and the metabolic process in vivo.
It also has potential applications in materials science. Through subsequent reactions, it can be integrated into polymer materials to give materials special properties, such as flame retardancy. Because halogen atoms can play a certain flame retardant role in the combustion process.
Furthermore, in the field of pesticides, pesticide products with high insecticidal, bactericidal or herbicidal activities can be created through rational derivatization.
In conclusion, 4-bromo-1-chloro-2 - (chloromethyl) benzene has shown important application value in many fields such as organic synthesis, drugs, materials, and pesticides due to its unique structure and reactivity, providing an indispensable material basis for the development of many chemical-related industries.
What are the synthesis methods of 4-bromo-1-chloro-2- (chloromethyl) benzene?
To prepare 4-bromo-1-chloro-2- (chloromethyl) benzene, the following method can be used.
First, use o-methyl chlorobenzene as the starting material. Before in a suitable solvent, under light conditions, the bromination reaction is carried out with bromine. Because methyl is an ortho-para-locator, and the bromine atom mainly replaces the hydrogen on the side chain when illuminated. In this way, o- (bromomethyl) chlorobenzene can be obtained. Then, under suitable chlorination conditions, such as Lewis acid (such as aluminum chloride), the product is reacted with chlorine gas. At this time, the chlorine atom will replace the hydrogen atom on the benzene ring in the ortho position with bromomethyl, and then 4-bromo-1-chloro-2 - (chloromethyl) benzene is obtained.
Second, p-chlorotoluene is used as the starting material. First, it reacts with chlorine under light, and the chlorine atom replaces the hydrogen on the methyl group to form p-chlorobenzyl chloride. After that, p-chlorobenzyl chloride is reacted with bromine under the action of a catalyst (such as iron powder), and the bromine atom will replace the hydrogen on the benzene ring in the ortho position with chloromethyl to obtain the target product 4-bromo-1-chloro-2- (chloromethyl) benzene.
Third, 2-methyl-4-chlorobenzoic acid is used as the starting material. It is first reduced to transform the carboxyl group into methyl, and 2-methyl-4-chlorobenzene can be obtained. Then it reacts with chlorine under light to realize the chlorination of methyl and generate 2- (chloromethyl) -4-chlorobenzene. Finally, this product is reacted with bromine under the action of a suitable catalyst (such as iron powder), so that the bromine atom replaces the hydrogen in the ortho position with chloromethyl on the benzene ring, and 4-bromo-1-chloro-2 - (chloromethyl) benzene can also be prepared.
These methods have their own advantages and disadvantages. In actual preparation, the most suitable method should be selected according to the comprehensive weighing of factors such as the availability of raw materials, the difficulty of reaction conditions, and the high and low yield.
First, use o-methyl chlorobenzene as the starting material. Before in a suitable solvent, under light conditions, the bromination reaction is carried out with bromine. Because methyl is an ortho-para-locator, and the bromine atom mainly replaces the hydrogen on the side chain when illuminated. In this way, o- (bromomethyl) chlorobenzene can be obtained. Then, under suitable chlorination conditions, such as Lewis acid (such as aluminum chloride), the product is reacted with chlorine gas. At this time, the chlorine atom will replace the hydrogen atom on the benzene ring in the ortho position with bromomethyl, and then 4-bromo-1-chloro-2 - (chloromethyl) benzene is obtained.
Second, p-chlorotoluene is used as the starting material. First, it reacts with chlorine under light, and the chlorine atom replaces the hydrogen on the methyl group to form p-chlorobenzyl chloride. After that, p-chlorobenzyl chloride is reacted with bromine under the action of a catalyst (such as iron powder), and the bromine atom will replace the hydrogen on the benzene ring in the ortho position with chloromethyl to obtain the target product 4-bromo-1-chloro-2- (chloromethyl) benzene.
Third, 2-methyl-4-chlorobenzoic acid is used as the starting material. It is first reduced to transform the carboxyl group into methyl, and 2-methyl-4-chlorobenzene can be obtained. Then it reacts with chlorine under light to realize the chlorination of methyl and generate 2- (chloromethyl) -4-chlorobenzene. Finally, this product is reacted with bromine under the action of a suitable catalyst (such as iron powder), so that the bromine atom replaces the hydrogen in the ortho position with chloromethyl on the benzene ring, and 4-bromo-1-chloro-2 - (chloromethyl) benzene can also be prepared.
These methods have their own advantages and disadvantages. In actual preparation, the most suitable method should be selected according to the comprehensive weighing of factors such as the availability of raw materials, the difficulty of reaction conditions, and the high and low yield.
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