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4-Bromo-1-Chloro-2-Methylbenzene
Linshang Chemical
|
HS Code |
999538 |
| Chemical Formula | C7H6BrCl |
| Molecular Weight | 191.48 |
| Appearance | Colorless to light yellow liquid |
| Odor | Characteristic aromatic odor |
| Density | 1.54 g/cm³ (approximate) |
| Boiling Point | 213 - 215 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | 87 °C (closed cup, approximate) |
As an accredited 4-Bromo-1-Chloro-2-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - bromo - 1 - chloro - 2 - methylbenzene in a sealed, chemical - resistant bottle. |
| Storage | 4 - bromo - 1 - chloro - 2 - methylbenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals. The storage area should be in compliance with safety regulations to minimize fire and explosion risks. |
| Shipping | 4 - bromo - 1 - chloro - 2 - methylbenzene is shipped in well - sealed, corrosion - resistant containers. It's labeled clearly as a chemical. Shipment follows strict regulations for hazardous substances, ensuring proper handling during transit. |
Competitive 4-Bromo-1-Chloro-2-Methylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
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What is the Chinese name for 4 - bromo - 1 - chloro - 2 - methylbenzene?
4-Bromo-1-chloro-2-methylbenzene, its naming follows the naming rules for organic compounds. In the nomenclature of aromatics, the benzene ring is used as the parent, and the different substituents attached to the benzene ring are listed in a certain order. Here, bromine (bromo), chloro (chloro) and methyl (methyl) are the substituents. According to the "order rule", the substituents with a smaller order are listed first. The atomic number of "bromine" is greater than "chlorine", but when naming, "bromine" is listed first, followed by "chlorine", and methyl is in the third place. Therefore, it is named 4-bromo-1-chloro-2-methylbenzene. This naming clearly indicates the type, quantity, and relative position of the substituents on the benzene ring, making it convenient for chemists to accurately communicate and recognize the structural characteristics of the compound. In the field of organic chemistry, the research, synthesis, and analysis of compounds, the standard naming is essential to ensure that all parties have a unified understanding of the same substance.
What are the physical properties of 4 - bromo - 1 - chloro - 2 - methylbenzene?
4-Bromo-1-chloro-2-methylbenzene is one of the organic compounds. Its physical properties are particularly important and are related to many uses and related reactions of this compound.
In terms of its appearance, it is usually a colorless to light yellow liquid with clear quality and a specific odor. Its boiling point is about 210-220 ° C. The boiling point is also the temperature at which the compound changes from liquid to gaseous state. This property is quite useful in the separation and purification of the compound.
As for the melting point, it is about -20 ° C. Melting point, the temperature at which the substance melts from solid to liquid. This value can help identify the compound and should also be paid attention to during storage and transportation.
The density of 4-bromo-1-chloro-2-methylbenzene is about 1.45-1.55g/cm ³, which is heavier than water, so when mixed with water, it sinks underwater.
In terms of solubility, this compound is insoluble in water, but can be soluble in organic solvents such as ethanol, ether, benzene, etc. This solubility characteristic is commonly used in organic synthesis and extraction processes.
In terms of volatility, 4-bromo-1-chloro-2-methyl benzene is volatile to a certain extent, and its vapor may accumulate in poorly ventilated areas.
In addition, its refractive index is also an important physical property, about 1.55 - 1.57, and the refractive index can be used to identify the purity and concentration of the compound.
In summary, the physical properties of 4-bromo-1-chloro-2-methylbenzene, such as appearance, boiling point, melting point, density, solubility, volatility, and refractive index, are essential for chemical research, industrial production, and related application fields.
In terms of its appearance, it is usually a colorless to light yellow liquid with clear quality and a specific odor. Its boiling point is about 210-220 ° C. The boiling point is also the temperature at which the compound changes from liquid to gaseous state. This property is quite useful in the separation and purification of the compound.
As for the melting point, it is about -20 ° C. Melting point, the temperature at which the substance melts from solid to liquid. This value can help identify the compound and should also be paid attention to during storage and transportation.
The density of 4-bromo-1-chloro-2-methylbenzene is about 1.45-1.55g/cm ³, which is heavier than water, so when mixed with water, it sinks underwater.
In terms of solubility, this compound is insoluble in water, but can be soluble in organic solvents such as ethanol, ether, benzene, etc. This solubility characteristic is commonly used in organic synthesis and extraction processes.
In terms of volatility, 4-bromo-1-chloro-2-methyl benzene is volatile to a certain extent, and its vapor may accumulate in poorly ventilated areas.
In addition, its refractive index is also an important physical property, about 1.55 - 1.57, and the refractive index can be used to identify the purity and concentration of the compound.
In summary, the physical properties of 4-bromo-1-chloro-2-methylbenzene, such as appearance, boiling point, melting point, density, solubility, volatility, and refractive index, are essential for chemical research, industrial production, and related application fields.
What are the chemical properties of 4 - bromo - 1 - chloro - 2 - methylbenzene?
4-Bromo-1-chloro-2-methylbenzene is also an organic compound. Its chemical properties are unique, and it is now the name of Jun Chen.
The first article is the electrophilic substitution reaction. The benzene ring is electron-rich and vulnerable to attack by electrophilic reagents. Because methyl is the power supply radical, the electron cloud density of the benzene ring can be increased, making the electrophilic substitution reaction more likely to occur. And the electron cloud density of the neighboring and para-position of methyl is especially increased, so the electrophilic substitution is mostly present in this position. For example, the adjacent and para-position of bromine atoms and chlorine atoms are easily replaced by electrophilic reagents such as nitro groups to form nitro-substituted derivatives.
The reaction of halogen atoms is discussed. This molecule contains bromine and chlorine dihalogen atoms, both of which have certain activity. Under suitable conditions, bromine atoms can be replaced by nucleophilic reagents. If treated with a strong base in an alcohol solution, bromine atoms may be replaced by hydroxyl groups to obtain phenolic derivatives; or react with cyano negative ions, bromine is replaced by cyano groups, and then hydrolyzed to obtain carboxylic acids. Although chlorine atoms are slightly less active than bromine atoms, under specific conditions, such as high temperature and strong nucleophilic reagents, similar substitution reactions can occur.
Furthermore, methyl groups are also reactive. Under the influence of benzene rings, the activity of hydrogen atoms on methyl groups is enhanced. In the presence of light or free radical initiators, hydrogen on methyl groups can be replaced by halogen radicals to form halogenated methyl benzene derivatives.
In summary, the interaction of 4-bromo-1-chloro-2-methylbenzene ring, halogen atom and methyl group exhibits diverse chemical properties and is widely used in the field of organic synthesis.
The first article is the electrophilic substitution reaction. The benzene ring is electron-rich and vulnerable to attack by electrophilic reagents. Because methyl is the power supply radical, the electron cloud density of the benzene ring can be increased, making the electrophilic substitution reaction more likely to occur. And the electron cloud density of the neighboring and para-position of methyl is especially increased, so the electrophilic substitution is mostly present in this position. For example, the adjacent and para-position of bromine atoms and chlorine atoms are easily replaced by electrophilic reagents such as nitro groups to form nitro-substituted derivatives.
The reaction of halogen atoms is discussed. This molecule contains bromine and chlorine dihalogen atoms, both of which have certain activity. Under suitable conditions, bromine atoms can be replaced by nucleophilic reagents. If treated with a strong base in an alcohol solution, bromine atoms may be replaced by hydroxyl groups to obtain phenolic derivatives; or react with cyano negative ions, bromine is replaced by cyano groups, and then hydrolyzed to obtain carboxylic acids. Although chlorine atoms are slightly less active than bromine atoms, under specific conditions, such as high temperature and strong nucleophilic reagents, similar substitution reactions can occur.
Furthermore, methyl groups are also reactive. Under the influence of benzene rings, the activity of hydrogen atoms on methyl groups is enhanced. In the presence of light or free radical initiators, hydrogen on methyl groups can be replaced by halogen radicals to form halogenated methyl benzene derivatives.
In summary, the interaction of 4-bromo-1-chloro-2-methylbenzene ring, halogen atom and methyl group exhibits diverse chemical properties and is widely used in the field of organic synthesis.
What are the main uses of 4 - bromo - 1 - chloro - 2 - methylbenzene?
4-Bromo-1-chloro-2-methylbenzene is one of the organic compounds. It has a wide range of uses and is widely used in the chemical industry.
First, it can be used as an intermediary in organic synthesis. It is often a key raw material in drug synthesis. Through many chemical reactions, it can be converted into compounds with specific pharmacological activities, thus laying the foundation for the creation of new drugs. For example, through a specific reaction process, complex drug molecular structures can be constructed to treat various diseases.
Second, it also has important functions in the field of materials science. It can be used as a starting material for the synthesis of special polymer materials. Through ingenious polymerization, it is introduced into the polymer chain to give the material unique properties, such as improving the material's heat resistance, chemical resistance, etc., making the material suitable for more severe environments.
Furthermore, it is also indispensable in dye synthesis. With the help of a series of chemical transformations, dyes with bright colors and good stability can be prepared. Due to its special molecular structure, it can produce unique absorption and emission of light, so dyes have excellent dyeing properties and are widely used in textiles, printing and dyeing industries.
In summary, 4-bromo-1-chloro-2-methylbenzene plays a crucial role in many fields such as organic synthesis, materials science, and dye synthesis, promoting the development and progress of related industries.
First, it can be used as an intermediary in organic synthesis. It is often a key raw material in drug synthesis. Through many chemical reactions, it can be converted into compounds with specific pharmacological activities, thus laying the foundation for the creation of new drugs. For example, through a specific reaction process, complex drug molecular structures can be constructed to treat various diseases.
Second, it also has important functions in the field of materials science. It can be used as a starting material for the synthesis of special polymer materials. Through ingenious polymerization, it is introduced into the polymer chain to give the material unique properties, such as improving the material's heat resistance, chemical resistance, etc., making the material suitable for more severe environments.
Furthermore, it is also indispensable in dye synthesis. With the help of a series of chemical transformations, dyes with bright colors and good stability can be prepared. Due to its special molecular structure, it can produce unique absorption and emission of light, so dyes have excellent dyeing properties and are widely used in textiles, printing and dyeing industries.
In summary, 4-bromo-1-chloro-2-methylbenzene plays a crucial role in many fields such as organic synthesis, materials science, and dye synthesis, promoting the development and progress of related industries.
What are the synthesis methods of 4 - bromo - 1 - chloro - 2 - methylbenzene?
To prepare 4-bromo-1-chloro-2-methylbenzene, the following methods can be used.
First, use o-methyl chlorobenzene as the starting material. Schilling o-methyl chlorobenzene and bromine undergo electrophilic substitution reaction under the action of catalysts such as iron bromide. In this case, because both methyl and chlorine atoms are ortho-para-sites, and the methyl activation is stronger than chlorine, bromine atoms will mainly replace methyl ortho-sites to obtain 4-bromo-1-chloro-2-methylbenzene. The reaction conditions of this process need to control the amount of bromine, the proportion of catalyst and the reaction temperature. If the amount of bromine is too high, it is feared to produce polybrominates; if the temperature is too high, it is also easy to cause more side reactions.
Second, take o-methyl bromobenzene as the starting material. Make it react with chlorine under light or specific catalyst conditions. When the light is irradiated, the chlorine radical reacts with o-methyl bromobenzene, and the hydrogen of methyl is replaced by chlorine. By adjusting the reaction conditions, such as light intensity, chlorine flow rate, reaction time, etc., the reaction can proceed in the direction of generating 4-bromo-1-chloro-2-methyl benzene. However, the selectivity of the light reaction is slightly inferior, or other chlorinated products are formed at other positions, which need to be carefully separated and purified.
Third, it can be started from 2 After the diazotization reaction, sodium nitrite and hydrochloric acid are used to convert the amino group into diazonium salts at low temperature. After that, cuprous bromide and cuprous chloride are added respectively, and the Sandmeier reaction is carried out. The diazonium group is replaced by bromine atom and chlorine atom to obtain the target product. This approach is a little more complicated, but the substitution position can be precisely controlled, and the product purity may be higher. However, the diazotization reaction needs to strictly control the temperature, and the use of sodium nitrite should also be cautious to prevent danger.
All synthesis methods have their own advantages and disadvantages. According to actual needs, factors such as the availability of raw materials, cost, and product purity should be considered to choose the best synthesis path.
First, use o-methyl chlorobenzene as the starting material. Schilling o-methyl chlorobenzene and bromine undergo electrophilic substitution reaction under the action of catalysts such as iron bromide. In this case, because both methyl and chlorine atoms are ortho-para-sites, and the methyl activation is stronger than chlorine, bromine atoms will mainly replace methyl ortho-sites to obtain 4-bromo-1-chloro-2-methylbenzene. The reaction conditions of this process need to control the amount of bromine, the proportion of catalyst and the reaction temperature. If the amount of bromine is too high, it is feared to produce polybrominates; if the temperature is too high, it is also easy to cause more side reactions.
Second, take o-methyl bromobenzene as the starting material. Make it react with chlorine under light or specific catalyst conditions. When the light is irradiated, the chlorine radical reacts with o-methyl bromobenzene, and the hydrogen of methyl is replaced by chlorine. By adjusting the reaction conditions, such as light intensity, chlorine flow rate, reaction time, etc., the reaction can proceed in the direction of generating 4-bromo-1-chloro-2-methyl benzene. However, the selectivity of the light reaction is slightly inferior, or other chlorinated products are formed at other positions, which need to be carefully separated and purified.
Third, it can be started from 2 After the diazotization reaction, sodium nitrite and hydrochloric acid are used to convert the amino group into diazonium salts at low temperature. After that, cuprous bromide and cuprous chloride are added respectively, and the Sandmeier reaction is carried out. The diazonium group is replaced by bromine atom and chlorine atom to obtain the target product. This approach is a little more complicated, but the substitution position can be precisely controlled, and the product purity may be higher. However, the diazotization reaction needs to strictly control the temperature, and the use of sodium nitrite should also be cautious to prevent danger.
All synthesis methods have their own advantages and disadvantages. According to actual needs, factors such as the availability of raw materials, cost, and product purity should be considered to choose the best synthesis path.
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