Linshang Chemical
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4-Bromo-2,3-Dichlorofluorobenzene
Linshang Chemical
|
HS Code |
384883 |
| Chemical Formula | C6H2BrCl2F |
| Molar Mass | 261.887 g/mol |
| Appearance | A colorless to light yellow liquid (estimated, based on similar halogenated benzenes) |
| Solubility In Water | Low solubility in water (hydrophobic due to non - polar benzene ring and halogen substituents) |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform, toluene (due to non - polar nature of molecule and similarity in intermolecular forces with organic solvents) |
| Vapor Pressure | Low vapor pressure (as it is a relatively heavy and non - volatile compound considering its halogen - substituted benzene structure) |
As an accredited 4-Bromo-2,3-Dichlorofluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - bromo - 2,3 - dichlorofluorobenzene packaged in a sealed glass bottle. |
| Storage | 4 - bromo - 2,3 - dichlorofluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames to prevent thermal decomposition or ignition. It should be kept in a tightly sealed container to avoid leakage and exposure to air and moisture, which could potentially react with the chemical. Store it separately from oxidizing agents and incompatible substances to prevent dangerous reactions. |
| Shipping | 4 - bromo - 2,3 - dichlorofluorobenzene is shipped in well - sealed, corrosion - resistant containers. It's transported following strict chemical shipping regulations, ensuring safety during transit to prevent any leakage or hazards. |
Competitive 4-Bromo-2,3-Dichlorofluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Bromo-2,3-Dichlorofluorobenzene in China?
As a trusted 4-Bromo-2,3-Dichlorofluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Bromo-2,3-Dichlorofluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4-bromo-2,3-dichlorobenzene?
4-Bromo-2,3-dichlorobutene has a wide range of uses. In the field of pharmaceutical synthesis, it is a key intermediate for many drugs. For example, in the preparation of some anti-infective drugs, its structural characteristics can be reacted with specific chemical reactions to construct active groups that interact with pathogens, which helps to enhance the efficacy and specificity of drugs.
In the creation of pesticides, it is an important raw material for the synthesis of high-efficiency and low-toxicity pesticides. It can give pesticides unique insecticidal, bactericidal or herbicidal activities through chemical modification, and reduce the impact on the environment and non-target organisms, meeting the needs of modern agricultural green development.
In the field of materials science, it can participate in the synthesis of functional polymer materials. Due to its halogen-containing atoms and unsaturated double bonds, it can be used as a polymerization monomer or crosslinking agent to improve the thermal stability, flame retardancy and mechanical properties of materials. For example, the preparation of engineering plastics, coatings or adhesives with special properties expands the scope of material applications.
is also an important synthetic building block in the field of organic synthetic chemistry. With its multi-functional group characteristics, chemists can construct complex organic molecular structures according to specific reaction strategies, providing a foundation for the development and exploration of new compounds and promoting the development of organic chemistry.
Its use depends on its unique chemical structure. The presence of bromine, chlorine atoms and carbon-carbon double bonds makes the molecule highly reactive and chemically selective, laying a chemical foundation for applications in various fields. It is an indispensable chemical for the development of organic synthetic chemistry and related industries.
In the creation of pesticides, it is an important raw material for the synthesis of high-efficiency and low-toxicity pesticides. It can give pesticides unique insecticidal, bactericidal or herbicidal activities through chemical modification, and reduce the impact on the environment and non-target organisms, meeting the needs of modern agricultural green development.
In the field of materials science, it can participate in the synthesis of functional polymer materials. Due to its halogen-containing atoms and unsaturated double bonds, it can be used as a polymerization monomer or crosslinking agent to improve the thermal stability, flame retardancy and mechanical properties of materials. For example, the preparation of engineering plastics, coatings or adhesives with special properties expands the scope of material applications.
is also an important synthetic building block in the field of organic synthetic chemistry. With its multi-functional group characteristics, chemists can construct complex organic molecular structures according to specific reaction strategies, providing a foundation for the development and exploration of new compounds and promoting the development of organic chemistry.
Its use depends on its unique chemical structure. The presence of bromine, chlorine atoms and carbon-carbon double bonds makes the molecule highly reactive and chemically selective, laying a chemical foundation for applications in various fields. It is an indispensable chemical for the development of organic synthetic chemistry and related industries.
What are the physical properties of 4-bromo-2,3-dichlorofluorobenzene?
4-Bromo-2,3-difluorostyrene is a genus of organic compounds. Its physical properties are particularly important and are related to many chemical applications.
This compound is mostly in a liquid state at room temperature and pressure, and may have a certain fluidity. Its color is usually almost colorless, or slightly light-colored, and its appearance is clear. This feature is easy to observe and identify in actual operation.
When it comes to odor, 4-bromo-2,3-difluorostyrene may emit a specific smell. However, due to individual olfactory differences, its description may vary. However, in general, it has many chemical odors unique to organic compounds.
Its density is also a key physical property. Due to the presence of bromine and fluorine atoms in the molecule, its density is higher than that of common hydrocarbon compounds. The relative atomic weight of bromine atoms is quite large, and the electronegativity of fluorine atoms is high, which has a significant impact on the intermolecular forces, making the compound molecules more tightly packed, resulting in higher density.
Boiling point is also an important property. In view of the existence of van der Waals forces between molecules, and the introduction of bromine and fluorine atoms enhances the intermolecular interaction, its boiling point is higher than that of simple styrene derivatives. In the process of separation and purification, this property can be separated from other substances by means of distillation and other means according to the difference in boiling points.
In terms of solubility, 4-bromo-2,3-difluorostyrene is an organic compound, so it exhibits good solubility in common organic solvents, such as ethanol, ether, dichloromethane, etc. This is because its molecular structure and organic solvent molecules can form a similar and soluble interaction, which is conducive to being used as a reactant or intermediate in organic synthesis reactions, uniformly dispersed in the reaction system, and promotes the smooth progress of the reaction.
Melting point is also the focus of consideration. Due to the particularity of molecular structure, the melting point or specific range of 4-bromo-2,3-difluorostyrene provides a reference for its storage and transportation.
This compound is mostly in a liquid state at room temperature and pressure, and may have a certain fluidity. Its color is usually almost colorless, or slightly light-colored, and its appearance is clear. This feature is easy to observe and identify in actual operation.
When it comes to odor, 4-bromo-2,3-difluorostyrene may emit a specific smell. However, due to individual olfactory differences, its description may vary. However, in general, it has many chemical odors unique to organic compounds.
Its density is also a key physical property. Due to the presence of bromine and fluorine atoms in the molecule, its density is higher than that of common hydrocarbon compounds. The relative atomic weight of bromine atoms is quite large, and the electronegativity of fluorine atoms is high, which has a significant impact on the intermolecular forces, making the compound molecules more tightly packed, resulting in higher density.
Boiling point is also an important property. In view of the existence of van der Waals forces between molecules, and the introduction of bromine and fluorine atoms enhances the intermolecular interaction, its boiling point is higher than that of simple styrene derivatives. In the process of separation and purification, this property can be separated from other substances by means of distillation and other means according to the difference in boiling points.
In terms of solubility, 4-bromo-2,3-difluorostyrene is an organic compound, so it exhibits good solubility in common organic solvents, such as ethanol, ether, dichloromethane, etc. This is because its molecular structure and organic solvent molecules can form a similar and soluble interaction, which is conducive to being used as a reactant or intermediate in organic synthesis reactions, uniformly dispersed in the reaction system, and promotes the smooth progress of the reaction.
Melting point is also the focus of consideration. Due to the particularity of molecular structure, the melting point or specific range of 4-bromo-2,3-difluorostyrene provides a reference for its storage and transportation.
What are the chemical properties of 4-bromo-2,3-dichlorofluorobenzene?
4-Bromo-2,3-difluorostyrene is an organic compound with unique chemical properties and is widely used in the field of organic synthesis. This compound contains carbon-carbon double bonds and halogen atoms, and has high reactivity. It can participate in many types of chemical reactions.
First, the carbon-carbon double bond can undergo an addition reaction. If it is used with hydrogen in a suitable catalyst, it can undergo a hydrogenation reaction. The double bond is added by hydrogen atoms to generate saturated 4-bromo-2,3-difluoroethylbenzene. This reaction requires the selection of a suitable catalyst, such as a palladium-carbon catalyst, and the reaction temperature and pressure must be controlled to obtain the desired reaction effect.
Second, halogen atoms can participate in nucleophilic substitution reactions. Due to the electronegativity difference between fluorine atoms and bromine atoms, bromine atoms are relatively easy to leave. When there are nucleophiles such as sodium alcohol and amine compounds, the nucleophiles will attack the carbon atoms connected to the bromine atoms, and the bromine atoms will leave to form new replacement products. For example, by reacting with sodium ethanol, corresponding ether compounds can be formed.
Third, this compound can also participate in typical reactions of halogenated aromatics. For example, in the presence of metal catalysts (such as copper, nickel, etc.), it can cross-couple with other organometallic reagents to achieve the construction of carbon-carbon bonds, providing an effective way for the synthesis of complex organic molecules.
In addition, due to the presence of fluorine atoms in the molecule, 4-bromo-2,3-difluorostyrene has certain chemical stability and unique physical properties. The introduction of fluorine atoms will change the electron cloud distribution of the molecule, affect its solubility, boiling point and other physical properties, and also affect its chemical reactivity and selectivity.
In short, 4-bromo-2,3-difluorostyrene has rich chemical reactivity due to its carbon-carbon double bonds and halogen atoms. It is a very valuable synthetic intermediate in the field of organic synthesis chemistry. A variety of organic compounds with special structures and functions can be synthesized by ingeniously designing reaction routes.
First, the carbon-carbon double bond can undergo an addition reaction. If it is used with hydrogen in a suitable catalyst, it can undergo a hydrogenation reaction. The double bond is added by hydrogen atoms to generate saturated 4-bromo-2,3-difluoroethylbenzene. This reaction requires the selection of a suitable catalyst, such as a palladium-carbon catalyst, and the reaction temperature and pressure must be controlled to obtain the desired reaction effect.
Second, halogen atoms can participate in nucleophilic substitution reactions. Due to the electronegativity difference between fluorine atoms and bromine atoms, bromine atoms are relatively easy to leave. When there are nucleophiles such as sodium alcohol and amine compounds, the nucleophiles will attack the carbon atoms connected to the bromine atoms, and the bromine atoms will leave to form new replacement products. For example, by reacting with sodium ethanol, corresponding ether compounds can be formed.
Third, this compound can also participate in typical reactions of halogenated aromatics. For example, in the presence of metal catalysts (such as copper, nickel, etc.), it can cross-couple with other organometallic reagents to achieve the construction of carbon-carbon bonds, providing an effective way for the synthesis of complex organic molecules.
In addition, due to the presence of fluorine atoms in the molecule, 4-bromo-2,3-difluorostyrene has certain chemical stability and unique physical properties. The introduction of fluorine atoms will change the electron cloud distribution of the molecule, affect its solubility, boiling point and other physical properties, and also affect its chemical reactivity and selectivity.
In short, 4-bromo-2,3-difluorostyrene has rich chemical reactivity due to its carbon-carbon double bonds and halogen atoms. It is a very valuable synthetic intermediate in the field of organic synthesis chemistry. A variety of organic compounds with special structures and functions can be synthesized by ingeniously designing reaction routes.
What is the production method of 4-bromo-2,3-dichlorofluorobenzene?
The preparation method of 4-bromo-2,3-difluorostyrene is as follows:
First take an appropriate amount of halogenated aromatics, which need to contain specific substitution positions of bromine atoms and fluorine atoms, and use them as starting materials. In a clean reactor, add an appropriate amount of organic solvent, such as dichloromethane, tetrahydrofuran, etc., which can effectively dissolve the raw material and subsequent added reagents, so that the reaction can proceed uniformly.
Then, add an appropriate amount of strong bases, such as potassium tert-butyl alcohol, sodium hydride, etc. to the reaction system. The function of strong bases is to capture hydrogen atoms in specific positions in halogenated aromatics, so that the molecular structure changes to form carbon negative ion intermediates. This step requires strict control of the reaction temperature and reaction time. The temperature is generally controlled in the low temperature range, such as -78 ° C to 0 ° C. Due to the high reactivity, high temperature can easily lead to side reactions, resulting in lower product purity.
Then add appropriate vinylating reagents, such as vinyl borate, vinyl halide, etc. The vinylating reagent will react with the carbon negative ion intermediate to form a new carbon-carbon bond, thereby constructing the basic carbon skeleton of the target product 4-bromo-2,3-difluorostyrene. In this reaction stage, the reaction conditions need to be finely regulated, such as the reaction temperature can be gradually raised to room temperature or even higher, depending on the specific reagent and reaction process. At the same time, an appropriate amount of catalyst, such as palladium catalyst, can be added to accelerate the reaction and improve the reaction yield.
After the reaction is completed, the reaction mixture is post-processed. Generally, the reaction is quenched with water to convert the excess strong base and unreacted reagents into water-soluble substances. Then, the organic phase is separated by extraction with an organic solvent. After that, the residual impurities in the reaction system, such as unreacted raw materials and by-products, can be removed by distillation, column chromatography, etc., and finally the pure 4-bromo-2,3-difluorostyrene product can be obtained. Throughout the preparation process, it is necessary to carefully control the reaction conditions of each step to ensure the smooth progress of the reaction in order to obtain the target product with high purity and high yield.
First take an appropriate amount of halogenated aromatics, which need to contain specific substitution positions of bromine atoms and fluorine atoms, and use them as starting materials. In a clean reactor, add an appropriate amount of organic solvent, such as dichloromethane, tetrahydrofuran, etc., which can effectively dissolve the raw material and subsequent added reagents, so that the reaction can proceed uniformly.
Then, add an appropriate amount of strong bases, such as potassium tert-butyl alcohol, sodium hydride, etc. to the reaction system. The function of strong bases is to capture hydrogen atoms in specific positions in halogenated aromatics, so that the molecular structure changes to form carbon negative ion intermediates. This step requires strict control of the reaction temperature and reaction time. The temperature is generally controlled in the low temperature range, such as -78 ° C to 0 ° C. Due to the high reactivity, high temperature can easily lead to side reactions, resulting in lower product purity.
Then add appropriate vinylating reagents, such as vinyl borate, vinyl halide, etc. The vinylating reagent will react with the carbon negative ion intermediate to form a new carbon-carbon bond, thereby constructing the basic carbon skeleton of the target product 4-bromo-2,3-difluorostyrene. In this reaction stage, the reaction conditions need to be finely regulated, such as the reaction temperature can be gradually raised to room temperature or even higher, depending on the specific reagent and reaction process. At the same time, an appropriate amount of catalyst, such as palladium catalyst, can be added to accelerate the reaction and improve the reaction yield.
After the reaction is completed, the reaction mixture is post-processed. Generally, the reaction is quenched with water to convert the excess strong base and unreacted reagents into water-soluble substances. Then, the organic phase is separated by extraction with an organic solvent. After that, the residual impurities in the reaction system, such as unreacted raw materials and by-products, can be removed by distillation, column chromatography, etc., and finally the pure 4-bromo-2,3-difluorostyrene product can be obtained. Throughout the preparation process, it is necessary to carefully control the reaction conditions of each step to ensure the smooth progress of the reaction in order to obtain the target product with high purity and high yield.
What are the precautions for the storage and transportation of 4-bromo-2,3-dichlorofluorobenzene?
4-Bromo-2,3-difluorophenylacetonitrile has a number of precautions to be paid attention to during storage and transportation.
When storing, the first choice of environment. It must be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its certain chemical activity, high temperature or intensified reaction can cause danger. This substance may be sensitive to air and moisture, so it should be sealed and stored to prevent deterioration in contact with air and moisture. The storage place should be separated from oxidants, acids, bases, etc., and must not be mixed with storage, because of contact or severe reaction. At the same time, the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment should be prepared, just in case.
When transporting, there are also many key points. The transportation vehicle must ensure that the vehicle is in good condition and has corresponding safety facilities. During transportation, it must be protected from exposure to the sun, rain, and high temperature. When handling, it should be handled lightly, and it should not be loaded and unloaded brutally, so as to avoid material leakage caused by damage to the container. During transportation, drivers and escorts must always be alert and familiar with the characteristics of the transported items and emergency treatment methods. In the event of an accident such as a leak, they should be dealt with quickly according to the established emergency plan, isolate the leaked contaminated area, and restrict personnel from entering and leaving. Emergency personnel should wear a full mask and protective clothing, and do not allow leaks to come into contact with combustible substances. If there is a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite; if there is a large amount of leakage, it is necessary to build a dike or dig a pit to contain it, transfer it to a special collector with a pump, recover it or transport it to a waste treatment site for disposal. In this way, it is necessary to ensure the safety of 4-bromo-2,3-difluorobenzene acetonitrile storage and transportation.
When storing, the first choice of environment. It must be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its certain chemical activity, high temperature or intensified reaction can cause danger. This substance may be sensitive to air and moisture, so it should be sealed and stored to prevent deterioration in contact with air and moisture. The storage place should be separated from oxidants, acids, bases, etc., and must not be mixed with storage, because of contact or severe reaction. At the same time, the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment should be prepared, just in case.
When transporting, there are also many key points. The transportation vehicle must ensure that the vehicle is in good condition and has corresponding safety facilities. During transportation, it must be protected from exposure to the sun, rain, and high temperature. When handling, it should be handled lightly, and it should not be loaded and unloaded brutally, so as to avoid material leakage caused by damage to the container. During transportation, drivers and escorts must always be alert and familiar with the characteristics of the transported items and emergency treatment methods. In the event of an accident such as a leak, they should be dealt with quickly according to the established emergency plan, isolate the leaked contaminated area, and restrict personnel from entering and leaving. Emergency personnel should wear a full mask and protective clothing, and do not allow leaks to come into contact with combustible substances. If there is a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite; if there is a large amount of leakage, it is necessary to build a dike or dig a pit to contain it, transfer it to a special collector with a pump, recover it or transport it to a waste treatment site for disposal. In this way, it is necessary to ensure the safety of 4-bromo-2,3-difluorobenzene acetonitrile storage and transportation.
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