Linshang Chemical
PRODUCTS
4-Bromo-2,6-Dichlorobenzenesulphonyl Chloride
Linshang Chemical
|
HS Code |
743370 |
| Chemical Formula | C6H2BrCl2O2SCl |
| Molar Mass | 329.31 g/mol |
| Appearance | Solid (presumably, based on similar compounds) |
| Physical State At Room Temp | Solid |
| Solubility In Water | Low (due to non - polar benzene ring and hydrophobic groups) |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Reactivity | Highly reactive towards nucleophiles, reacts with amines, alcohols |
As an accredited 4-Bromo-2,6-Dichlorobenzenesulphonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 4 - bromo - 2,6 - dichlorobenzenesulphonyl Chloride in a sealed glass bottle. |
| Storage | 4 - bromo - 2,6 - dichlorobenzenesulphonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent moisture ingress, as it may react with water. Store it separately from incompatible substances like bases and reducing agents to avoid potential chemical reactions. |
| Shipping | 4 - bromo - 2,6 - dichlorobenzenesulphonyl chloride is a chemical. It should be shipped in tightly sealed, corrosion - resistant containers, following strict hazardous materials regulations to prevent spills and ensure safe transport. |
Competitive 4-Bromo-2,6-Dichlorobenzenesulphonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Bromo-2,6-Dichlorobenzenesulphonyl Chloride in China?
As a trusted 4-Bromo-2,6-Dichlorobenzenesulphonyl Chloride manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Bromo-2,6-Dichlorobenzenesulphonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 4-bromo-2, 6-dichlorobenzenesulphonyl Chloride?
4-Bromo-2,6-dichlorobenzenesulfonyl chloride, this is an organic compound. It is active and has significant chemical activity.
Looking at its structure, bromine and chlorine atoms are connected to the benzene ring, and contain sulfonyl chloride groups. Sulfonyl chloride groups (-SO 2O Cl) are very active and easily participate in many chemical reactions.
In terms of their reactivity, the chlorine atoms in the sulfonyl chloride group are easily replaced by nucleophiles. In case of alcohols, nucleophilic substitution reactions can occur to generate corresponding sulfonates. For example, when reacted with ethanol, the hydroxyl oxygen atoms in ethanol act as nucleophiles to attack the sulfur atoms of sulfonyl chloride, and the chlorine atoms leave to form ethyl sulfonate.
In case of amines, nucleophilic substitution can also occur to form sulfonamides. This reaction is often used in organic synthesis to construct nitrogen-containing functional groups.
Furthermore, although the bromine and chlorine atoms on the benzene ring are slightly less active than the sulfonyl chloride group, they can also participate in nucleophilic substitution or metal-catalyzed coupling reactions under specific conditions, such as strong bases and suitable catalysts. For example, under palladium catalysis, Suzuki coupling reaction can occur with compounds containing borate esters to realize the construction of carbon-carbon bonds on the benzene ring, and then modify and expand the molecular structure. Due to its active chemical properties, 4-bromo-2,6-dichlorobenzenesulfonyl chloride is widely used in the field of organic synthesis. It is often used as a key intermediate to prepare various organic compounds with specific structures and functions, such as drugs, pesticides, and functional materials.
Looking at its structure, bromine and chlorine atoms are connected to the benzene ring, and contain sulfonyl chloride groups. Sulfonyl chloride groups (-SO 2O Cl) are very active and easily participate in many chemical reactions.
In terms of their reactivity, the chlorine atoms in the sulfonyl chloride group are easily replaced by nucleophiles. In case of alcohols, nucleophilic substitution reactions can occur to generate corresponding sulfonates. For example, when reacted with ethanol, the hydroxyl oxygen atoms in ethanol act as nucleophiles to attack the sulfur atoms of sulfonyl chloride, and the chlorine atoms leave to form ethyl sulfonate.
In case of amines, nucleophilic substitution can also occur to form sulfonamides. This reaction is often used in organic synthesis to construct nitrogen-containing functional groups.
Furthermore, although the bromine and chlorine atoms on the benzene ring are slightly less active than the sulfonyl chloride group, they can also participate in nucleophilic substitution or metal-catalyzed coupling reactions under specific conditions, such as strong bases and suitable catalysts. For example, under palladium catalysis, Suzuki coupling reaction can occur with compounds containing borate esters to realize the construction of carbon-carbon bonds on the benzene ring, and then modify and expand the molecular structure. Due to its active chemical properties, 4-bromo-2,6-dichlorobenzenesulfonyl chloride is widely used in the field of organic synthesis. It is often used as a key intermediate to prepare various organic compounds with specific structures and functions, such as drugs, pesticides, and functional materials.
What are the main uses of 4-bromo-2, 6-dichlorobenzenesulphonyl Chloride
4-Bromo-2,6-dichlorobenzenesulfonyl chloride has a wide range of uses in chemical industry.
First, it can be a key intermediate in the process of pharmaceutical creation. Taking the preparation of a certain type of antibacterial drug as an example, the introduction of a specific group in its structure often depends on this compound. Through delicate organic synthesis steps, it is coupled with a specific amine or nitrogen-containing heterocyclic compound, and by suitable reaction conditions, such as in an inert solvent, under the catalysis of a base, the sulfonyl chloride group undergoes nucleophilic substitution with an amine group, and then a novel compound structure with antibacterial activity is constructed.
Second, it is also important in the field of pesticide development. It can be used as an important starting material for the synthesis of highly efficient insecticides or herbicides. For example, by reacting with specific alcohols or phenolic compounds, benzenesulfonyl ester derivatives with unique biological activities can be generated. Such derivatives can precisely regulate their chemical structure, change their mechanism of action and affinity for target organisms, thereby improving the efficacy and selectivity of pesticides, and providing powerful chemical tools for agricultural pest control and weed control.
Furthermore, in the field of materials science, its use should not be underestimated. In the synthesis of some functional polymer materials, it can be introduced into the polymer backbone as a functional monomer. When free radical polymerization is carried out with monomers containing double bonds, the formed polymer imparts unique properties such as good hydrophilicity, thermal stability or special surface activity to the material due to the presence of benzenesulfonyl chloride groups, which contributes greatly to the modification and optimization of materials such as coatings and adhesives.
First, it can be a key intermediate in the process of pharmaceutical creation. Taking the preparation of a certain type of antibacterial drug as an example, the introduction of a specific group in its structure often depends on this compound. Through delicate organic synthesis steps, it is coupled with a specific amine or nitrogen-containing heterocyclic compound, and by suitable reaction conditions, such as in an inert solvent, under the catalysis of a base, the sulfonyl chloride group undergoes nucleophilic substitution with an amine group, and then a novel compound structure with antibacterial activity is constructed.
Second, it is also important in the field of pesticide development. It can be used as an important starting material for the synthesis of highly efficient insecticides or herbicides. For example, by reacting with specific alcohols or phenolic compounds, benzenesulfonyl ester derivatives with unique biological activities can be generated. Such derivatives can precisely regulate their chemical structure, change their mechanism of action and affinity for target organisms, thereby improving the efficacy and selectivity of pesticides, and providing powerful chemical tools for agricultural pest control and weed control.
Furthermore, in the field of materials science, its use should not be underestimated. In the synthesis of some functional polymer materials, it can be introduced into the polymer backbone as a functional monomer. When free radical polymerization is carried out with monomers containing double bonds, the formed polymer imparts unique properties such as good hydrophilicity, thermal stability or special surface activity to the material due to the presence of benzenesulfonyl chloride groups, which contributes greatly to the modification and optimization of materials such as coatings and adhesives.
What is the preparation method of 4-bromo-2, 6-dichlorobenzenesulphonyl Chloride
To prepare 4-bromo-2,6-dichlorobenzenesulfonyl chloride, the following method can be followed.
Take 2,6-dichlorobenzene as the starting material. This compound can be obtained by halogenation reaction. Add 2,6-dichlorobenzene to a suitable reaction vessel, add an appropriate amount of brominating reagent, such as liquid bromine, and add a suitable catalyst, such as iron powder or iron tribromide. Under these conditions, bromine atoms can selectively replace hydrogen atoms at specific positions on the benzene ring to generate 2,6-dichlorobenzene.
After obtaining 2,6-dichlorobenzene, it is sulfonated with fuming sulfuric acid or chlorosulfonic acid. 2,6-Dichlorobenzene is slowly added to a reactor containing fuming sulfuric acid or chlorosulfonic acid to control the reaction temperature and reaction time. During this process, the hydrogen atom on the benzene ring is replaced by a sulfonic acid group (-SO-H) to form 4-bromo-2,6-dichlorobenzenesulfonic acid.
Subsequently, 4-bromo-2,6-dichlorobenzenesulfonic acid is converted to 4-bromo-2,6-dichlorobenzenesulfonic acid chloride. Sulfoxide chloride (SOCl _ 2) is often used as a chlorination reagent. 4-Bromo-2,6-dichlorobenzenesulfonic acid and thionyl chloride are placed in a reaction bottle, and an appropriate amount of organic bases such as pyridine can be added as catalysts. After heating the reaction, the hydroxyl group in the sulfonic acid group is replaced by chlorine atoms to obtain 4-bromo-2,6-dichlorobenzenesulfonyl chloride. After the reaction, a series of separation and purification methods such as distillation, extraction, and recrystallization can obtain pure 4-bromo-2,6-dichlorobenzenesulfonyl chloride products. The whole process requires strict control of the reaction conditions to ensure the smooth progress of the reaction and the purity of the product.
Take 2,6-dichlorobenzene as the starting material. This compound can be obtained by halogenation reaction. Add 2,6-dichlorobenzene to a suitable reaction vessel, add an appropriate amount of brominating reagent, such as liquid bromine, and add a suitable catalyst, such as iron powder or iron tribromide. Under these conditions, bromine atoms can selectively replace hydrogen atoms at specific positions on the benzene ring to generate 2,6-dichlorobenzene.
After obtaining 2,6-dichlorobenzene, it is sulfonated with fuming sulfuric acid or chlorosulfonic acid. 2,6-Dichlorobenzene is slowly added to a reactor containing fuming sulfuric acid or chlorosulfonic acid to control the reaction temperature and reaction time. During this process, the hydrogen atom on the benzene ring is replaced by a sulfonic acid group (-SO-H) to form 4-bromo-2,6-dichlorobenzenesulfonic acid.
Subsequently, 4-bromo-2,6-dichlorobenzenesulfonic acid is converted to 4-bromo-2,6-dichlorobenzenesulfonic acid chloride. Sulfoxide chloride (SOCl _ 2) is often used as a chlorination reagent. 4-Bromo-2,6-dichlorobenzenesulfonic acid and thionyl chloride are placed in a reaction bottle, and an appropriate amount of organic bases such as pyridine can be added as catalysts. After heating the reaction, the hydroxyl group in the sulfonic acid group is replaced by chlorine atoms to obtain 4-bromo-2,6-dichlorobenzenesulfonyl chloride. After the reaction, a series of separation and purification methods such as distillation, extraction, and recrystallization can obtain pure 4-bromo-2,6-dichlorobenzenesulfonyl chloride products. The whole process requires strict control of the reaction conditions to ensure the smooth progress of the reaction and the purity of the product.
4-Bromo-2, 6-dichlorobenzenesulphonyl Chloride What to pay attention to when storing and transporting
4-Bromo-2,6-dichlorobenzenesulfonyl chloride is a chemical substance. When storing and transporting, many things need to be paid attention to.
When storing, the first environment. When placed in a cool, dry and well-ventilated place. This may cause deterioration due to its nature or fear of moisture, heat, or damp heat. If it is in a humid place, water vapor is easy to interact with it, triggering reactions such as hydrolysis, damaging its purity and quality; if it is heated, or the reactivity changes, it may even be safe.
Furthermore, it needs to be isolated from other substances. Do not store with alkalis, alcohols, etc. The alkali can react with the sulfonyl chloride group, and the alcohol can also react with it, which will change its chemical properties and lose its original properties.
Packaging is also critical. Use a suitable container to ensure a good seal. To prevent the intrusion of air, water vapor, etc., and the packaging material should be able to withstand the corrosion of this material and not react with it.
When transporting, also pay attention to it. The transportation vehicle should be clean, dry, and free of residual reactions. The driving process should be smooth and avoid bumps and vibrations to avoid packaging damage.
Escort personnel also need to be professional and familiar with the nature of this material and emergency treatment methods. In the event of an accident, such as package damage and leakage, appropriate measures can be taken quickly to prevent the damage from expanding. If the leakage is adsorbed with suitable adsorption materials, it should be properly collected and disposed of to prevent environmental pollution. In short, the storage and transportation of 4-bromo-2,6-dichlorobenzenesulfonyl chloride must be done with caution and in accordance with regulations to ensure its safety and quality.
When storing, the first environment. When placed in a cool, dry and well-ventilated place. This may cause deterioration due to its nature or fear of moisture, heat, or damp heat. If it is in a humid place, water vapor is easy to interact with it, triggering reactions such as hydrolysis, damaging its purity and quality; if it is heated, or the reactivity changes, it may even be safe.
Furthermore, it needs to be isolated from other substances. Do not store with alkalis, alcohols, etc. The alkali can react with the sulfonyl chloride group, and the alcohol can also react with it, which will change its chemical properties and lose its original properties.
Packaging is also critical. Use a suitable container to ensure a good seal. To prevent the intrusion of air, water vapor, etc., and the packaging material should be able to withstand the corrosion of this material and not react with it.
When transporting, also pay attention to it. The transportation vehicle should be clean, dry, and free of residual reactions. The driving process should be smooth and avoid bumps and vibrations to avoid packaging damage.
Escort personnel also need to be professional and familiar with the nature of this material and emergency treatment methods. In the event of an accident, such as package damage and leakage, appropriate measures can be taken quickly to prevent the damage from expanding. If the leakage is adsorbed with suitable adsorption materials, it should be properly collected and disposed of to prevent environmental pollution. In short, the storage and transportation of 4-bromo-2,6-dichlorobenzenesulfonyl chloride must be done with caution and in accordance with regulations to ensure its safety and quality.
What are the effects of 4-bromo-2, 6-dichlorobenzenesulphonyl Chloride on the environment and human body?
4-Bromo-2,6-dichlorobenzenesulfonyl chloride is a commonly used reagent in organic synthesis. This substance has an impact on the environment and human body, and cannot be ignored.
In terms of the environment, it enters the natural environment, and it is difficult to degrade due to its stable chemical properties. And its structure contains halogen atoms such as bromine and chlorine, which may interfere with the normal operation of the ecosystem. If released into water, the electronegativity of halogen atoms causes the compound to have a certain polarity, or it can be dissolved in water, posing a threat to the survival of aquatic organisms. After ingestion by aquatic organisms, it may cause physiological disorders and affect population reproduction. Entering the soil, or adsorbing on soil particles, changing soil physical and chemical properties, affecting the activities of soil microorganisms and the growth of plant roots.
In terms of personal effects, it is irritating. If accidentally touching the skin, it can cause skin redness, swelling, pain, burns, etc. Because it can react with biological macromolecules such as proteins on the surface of the skin, destroying the normal structure and function of the skin. If it comes into contact with the eyes, the damage is more serious, or it may cause congestion of the conjunctiva, corneal damage, and even affect vision. If inhaled, its volatile gaseous particles can irritate the respiratory mucosa, causing symptoms such as cough, asthma, and breathing difficulties. Long-term exposure may damage the respiratory system and increase the risk of respiratory diseases. And because of its special chemical structure, it may have potential carcinogenicity and teratogenicity. Although the exact evidence needs to be further studied, the latent risk cannot be ignored. Therefore, when using 4-bromo-2,6-dichlorobenzenesulfonyl chloride, follow strict operating procedures and take protective measures to reduce its harm to the environment and people.
In terms of the environment, it enters the natural environment, and it is difficult to degrade due to its stable chemical properties. And its structure contains halogen atoms such as bromine and chlorine, which may interfere with the normal operation of the ecosystem. If released into water, the electronegativity of halogen atoms causes the compound to have a certain polarity, or it can be dissolved in water, posing a threat to the survival of aquatic organisms. After ingestion by aquatic organisms, it may cause physiological disorders and affect population reproduction. Entering the soil, or adsorbing on soil particles, changing soil physical and chemical properties, affecting the activities of soil microorganisms and the growth of plant roots.
In terms of personal effects, it is irritating. If accidentally touching the skin, it can cause skin redness, swelling, pain, burns, etc. Because it can react with biological macromolecules such as proteins on the surface of the skin, destroying the normal structure and function of the skin. If it comes into contact with the eyes, the damage is more serious, or it may cause congestion of the conjunctiva, corneal damage, and even affect vision. If inhaled, its volatile gaseous particles can irritate the respiratory mucosa, causing symptoms such as cough, asthma, and breathing difficulties. Long-term exposure may damage the respiratory system and increase the risk of respiratory diseases. And because of its special chemical structure, it may have potential carcinogenicity and teratogenicity. Although the exact evidence needs to be further studied, the latent risk cannot be ignored. Therefore, when using 4-bromo-2,6-dichlorobenzenesulfonyl chloride, follow strict operating procedures and take protective measures to reduce its harm to the environment and people.
Scan to WhatsApp
