4-Bromo-3,5-Dichloro-1-(Trifluoromethoxy)Benzene
Linshang Chemical
HS Code |
883681 |
Chemical Formula | C7H2BrCl2F3O |
Molecular Weight | 307.9 |
Appearance | Typically a colorless to light - colored liquid or solid |
Boiling Point | Varies, but can be in a certain temperature range based on purity (approx. depending on conditions) |
Melting Point | Specific value depending on purity and crystal form |
Density | Characteristic density value in g/cm³ |
Solubility In Water | Low solubility in water |
Solubility In Organic Solvents | Soluble in some common organic solvents like dichloromethane, toluene etc. |
Vapor Pressure | Vapor pressure value at a given temperature |
Flash Point | Flash point value indicating flammability risk |
As an accredited 4-Bromo-3,5-Dichloro-1-(Trifluoromethoxy)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 100g of 4 - bromo - 3,5 - dichloro - 1 - (trifluoromethoxy)benzene in sealed chemical - grade container. |
Storage | Store 4 - bromo - 3,5 - dichloro - 1 - (trifluoromethoxy)benzene in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent leakage and exposure to air and moisture. Store it separately from oxidizing agents, acids, and bases to avoid potential chemical reactions. |
Shipping | 4 - bromo - 3,5 - dichloro - 1 - (trifluoromethoxy)benzene is shipped in sealed, corrosion - resistant containers. Strict safety protocols are followed, ensuring proper labeling and compliance with regulations for transporting hazardous chemicals. |
Competitive 4-Bromo-3,5-Dichloro-1-(Trifluoromethoxy)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 4-Bromo-3,5-Dichloro-1-(Trifluoromethoxy)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In this compound, the functional groups of bromine, chlorine and trifluoromethoxy give it specific reactivity. The bromine atom is active and can introduce other groups to the compound through nucleophilic substitution, resulting in a new organic structure. The dichloro atom is on the benzene ring. Due to the electronegativity of chlorine, it can affect the electron cloud density distribution of the benzene ring, and left and right the reaction check point and activity. Trifluoromethoxy, with its strong electron-absorbing properties, has a significant impact on the physical and chemical properties of compounds, such as enhancing the fat solubility of compounds, changing their boiling point, melting point and other physical parameters.
Its chemical properties make the compound useful in many fields such as medicine, pesticides and materials science. In pharmaceutical research and development, it can be used to synthesize specific biologically active molecules, such as drugs designed to have high affinity for specific targets. In the field of pesticides, use its chemical properties to create high-efficiency, low-toxicity and environmentally friendly pesticides. In materials science, it can be used as a key intermediate in the construction of functional materials to prepare materials with special optical and electrical properties.
In conclusion, 4-bromo-3,5-dichloro-1 - (trifluoromethoxy) benzene plays an important role in many scientific fields due to its unique chemical properties, and is a key object of organic synthetic chemistry research.
In the field of medicinal chemistry, it can be used as a key intermediate for the synthesis of a variety of biologically active compounds. Due to the presence of halogen atoms and trifluoromethoxy groups in the structure, the compound is endowed with unique physical and chemical properties, which can affect the interaction between the synthesized drug and the biological target, and is of great significance to drug development. Or it can participate in the construction of a specific drug molecular skeleton, laying the foundation for the creation of new drugs.
In the field of pesticides, it is also of great value. With its unique chemical structure, it can be used as a starting material for the synthesis of high-efficiency pesticides. With the help of chemical modification, pesticides can be given better insecticidal, bactericidal or herbicidal properties. For example, the introduction of trifluoromethoxy can enhance the lipophilicity of pesticides, enhance their permeability and transport ability in organisms, and then improve their efficacy.
In the field of materials science, it can be used to prepare functional materials. For example, participating in the synthesis of materials with special optical and electrical properties, whose structural properties may endow the materials with unique photoelectric response, shows potential application prospects in the field of optoelectronic device manufacturing, such as organic Light Emitting Diode (OLED), solar cells, etc.
This compound has important uses in medicine, pesticides, materials science and other fields due to its unique chemical structure, providing a key foundation for technological innovation and development in various fields.
First, the compound containing the benzene ring is used as the starting material. The bromine atom is introduced at a specific position of the benzene ring first, and the reaction conditions need to be carefully selected in this step. Usually, the benzene ring can be reacted with the brominating reagent under the action of an appropriate catalyst, such as iron or iron salt as the catalyst. Under mild heating conditions, the bromine atom can preferably enter the predetermined position of the benzene ring to obtain the bromine-containing intermediate.
Second, introduce chlorine atoms on the intermediate. Appropriate chlorination reagents, such as chlorine or chlorine-containing compounds, can be selected to achieve dichloro substitution at a specific position in the benzene ring under light or catalysis of a specific catalyst. In this process, precise control of reaction conditions is crucial, such as temperature, reactant ratio, etc. If there is a slight difference, the product will be impure.
Furthermore, to introduce trifluoromethoxy, special reagents and reaction paths are often required. Generally, reagents containing trifluoromethoxy can be selected to react with bromine and chlorine-containing benzene ring intermediates in an alkaline environment or in a specific solvent. Factors such as the strength of the base and the polar solvent have a profound impact on the reaction process and product yield.
There is also a strategy of using other compounds as starting materials and gradually constructing target molecules through multi-step transformation. However, this approach often requires more complicated reaction steps and fine reaction control, but its advantage lies in the variety of raw material choices, which can be flexibly selected according to actual needs and resource conditions.
Although there are many methods of synthesis, in actual operation, it is necessary to comprehensively consider the availability of raw materials, the cost, the difficulty of controlling reaction conditions, and the purity and yield of products. Only by carefully weighing can we find the optimal synthesis path to achieve twice the result with half the effort.
First storage, this compound should be placed in a cool, dry and well ventilated place. Cover because of its nature or sensitive to temperature and humidity, if it is in a high temperature and humid environment, it may cause deterioration and damage its chemical properties. And it must be kept away from fire and heat sources. Open flames and hot topics can easily lead to chemical reactions and cause danger.
Furthermore, it should be stored separately from oxidants, acids, bases and other substances. Due to its chemical activity, it can mix with various chemicals, or react violently, causing the risk of fire and explosion. The storage place should also be equipped with suitable materials to contain leaks, so as to prevent accidents and dispose of them in time to prevent pollution from expanding.
As for transportation, caution is also required. Transportation vehicles should ensure that they are in good condition and have complete fire and emergency equipment. When loading and unloading, the operation must be gentle to avoid collisions and falls, so as to prevent material leakage due to damaged packaging. During transportation, the condition of the goods should be checked regularly to check whether the packaging is damaged and whether the materials are leaking. If passing through densely populated areas or environmentally sensitive areas, it is necessary to be extra careful and drive according to the established route and time to avoid accidents.
Transportation packaging is also crucial. Choose suitable packaging materials to ensure a good seal and withstand certain external shocks and environmental changes to protect the safety of the material during transportation. In this way, during the storage and transportation of 4-bromo-3,5-dichloro-1 - (trifluoromethoxy) benzene, pay attention to all matters to ensure its safety and avoid danger.
At the environmental level, such halogenated organic compounds may have certain stability and refractory degradation due to their special chemical structure. If released into the natural environment, they may remain in soil or water for a long time. In soil, it may affect the structure and function of soil microbial community, interfere with normal soil ecological processes, and cause changes in soil fertility and self-purification capacity. Inflow into water bodies, or pose a threat to aquatic organisms. Because it is fat-soluble, or enriched in aquatic organisms, it is transmitted and amplified through the food chain, causing potential harm to advanced organisms and destroying the balance of aquatic ecosystems.
As for the impact on the human body, because the compound contains bromine, chlorine, fluorine and other halogen elements and methoxy structures, or has certain biological activity and toxicity. After entering the human body through respiratory tract, skin contact or accidental ingestion, it may interfere with the normal physiological and biochemical processes of the human body. Or affect the nervous system, causing dizziness, fatigue, neurological disorders and other symptoms. It may also interfere with the endocrine system, affect hormone secretion and regulation, and then affect important physiological functions such as human growth and development and reproduction. Long-term exposure may increase the risk of cancer due to its halogenated structure during metabolism in the body or the generation of carcinogenic active intermediates.
In summary, 4-bromo-3,5-dichloro-1 - (trifluoromethoxy) benzene poses latent risks to the environment and the human body. Its production, use and discharge must be strictly controlled to reduce its harm to the ecological environment and human health.

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