Linshang Chemical
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4-(Bromomethyl)-1-Chloro-2-Fluorobenzene
Linshang Chemical
|
HS Code |
144483 |
| Chemical Formula | C7H5BrClF |
| Molecular Weight | 223.47 |
| Physical State At Room Temp | Likely liquid or solid |
| Solubility In Water | Low (organic halide, non - polar nature) |
| Solubility In Organic Solvents | Good (in common organic solvents like dichloromethane) |
| Stability | Stable under normal conditions, but reactive towards strong bases/nucleophiles |
As an accredited 4-(Bromomethyl)-1-Chloro-2-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4-(bromomethyl)-1-chloro-2-fluorobenzene packaged in a sealed glass bottle. |
| Storage | 4-(Bromomethyl)-1-chloro-2-fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to prevent potential reactions. Label the storage container clearly with relevant hazard information. |
| Shipping | 4-(Bromomethyl)-1-chloro-2-fluorobenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring safe transportation to prevent spills and environmental or safety risks. |
Competitive 4-(Bromomethyl)-1-Chloro-2-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-(Bromomethyl)-1-Chloro-2-Fluorobenzene in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-(Bromomethyl)-1-Chloro-2-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 4- (bromomethyl) -1-chloro-2-fluorobenzene?
4- (bromomethyl) -1-chloro-2-fluorobenzene is also an organic compound. Its main use can be found in the field of organic synthesis.
First, in the creation of new pharmaceutical molecules, this compound may be a key intermediate. Due to the characteristics of halogen atoms and bromomethyl atoms in its structure, it can be connected to other molecular fragments through various chemical reactions to construct structures with specific biological activities. For example, bromomethyl can be reacted with compounds containing nucleophilic groups such as nitrogen and oxygen through nucleophilic substitution, thereby expanding the molecular structure to find potential pharmaceutical ingredients with therapeutic effects.
Second, in the field of materials science, it also has applications. Can participate in the preparation of polymer materials with special properties. By introducing this compound into the polymer chain through appropriate polymerization reactions, the physical and chemical properties of the polymer can be adjusted by the electronic and spatial effects of halogen atoms and fluorine atoms, such as solubility, thermal stability and electrical properties. For example, high-performance polymer materials for insulating layers of electronic devices are prepared to improve the dielectric properties of the materials.
Third, in the field of pesticide chemistry, it can be used as a starting material for the synthesis of new pesticides. Using its unique chemical structure, pesticide products with high inhibition or killing effects on specific pests or pathogens can be created through a series of reactions. Due to the presence of halogen atoms, the interaction between pesticide molecules and specific receptors in target organisms may be enhanced, and the biological activity and selectivity of pesticides can be improved.
First, in the creation of new pharmaceutical molecules, this compound may be a key intermediate. Due to the characteristics of halogen atoms and bromomethyl atoms in its structure, it can be connected to other molecular fragments through various chemical reactions to construct structures with specific biological activities. For example, bromomethyl can be reacted with compounds containing nucleophilic groups such as nitrogen and oxygen through nucleophilic substitution, thereby expanding the molecular structure to find potential pharmaceutical ingredients with therapeutic effects.
Second, in the field of materials science, it also has applications. Can participate in the preparation of polymer materials with special properties. By introducing this compound into the polymer chain through appropriate polymerization reactions, the physical and chemical properties of the polymer can be adjusted by the electronic and spatial effects of halogen atoms and fluorine atoms, such as solubility, thermal stability and electrical properties. For example, high-performance polymer materials for insulating layers of electronic devices are prepared to improve the dielectric properties of the materials.
Third, in the field of pesticide chemistry, it can be used as a starting material for the synthesis of new pesticides. Using its unique chemical structure, pesticide products with high inhibition or killing effects on specific pests or pathogens can be created through a series of reactions. Due to the presence of halogen atoms, the interaction between pesticide molecules and specific receptors in target organisms may be enhanced, and the biological activity and selectivity of pesticides can be improved.
What are the physical properties of 4- (bromomethyl) -1-chloro-2-fluorobenzene
4- (bromomethyl) -1-chloro-2-fluorobenzene is one of the organic compounds. Its physical properties are quite worthy of investigation.
First of all, its appearance, under normal temperature and pressure, this material is mostly colorless to light yellow liquid, and it is quite mobile. Under sunlight, its slightly flickering luster may be seen.
As for its boiling point, it is about a certain temperature range. Due to the force between molecules, its boiling point can be maintained at a specific value. The existence of this value makes it change from liquid to gas at a specific temperature. The characteristics of this boiling point are crucial in the experimental operation of separation and purification.
In terms of melting point, there are also specific values. When the temperature drops below the melting point, the substance will solidify from liquid to solid, and the molecular arrangement will gradually become orderly from disorder, forming a regular lattice structure.
In terms of solubility, 4- (bromomethyl) -1-chloro-2-fluorobenzene exhibits good solubility in organic solvents, such as common ether, dichloromethane, etc. Due to the electronegativity of each atom in the molecular structure, it has a certain polarity, and can form interactions such as van der Waals forces with organic solvent molecules, so it can be fused. However, in water, its solubility is poor. Water is a strong polar solvent, and the interaction with the compound molecules is weak, making it difficult to dissolve in water.
Density is also one of its important physical properties. Its density is higher than that of water, so if it is mixed with water and left to stand, it will sink to the bottom. This property can be used in some processes involving liquid-liquid separation.
In addition, its vapor pressure cannot be ignored. At a certain temperature, the vapor pressure of this substance determines the degree of difficulty in volatilization. The higher the vapor pressure, the more easily it will evaporate into the gas phase under the same conditions. During storage and use, attention should be paid to prevent excessive evaporation from causing losses or causing safety problems.
First of all, its appearance, under normal temperature and pressure, this material is mostly colorless to light yellow liquid, and it is quite mobile. Under sunlight, its slightly flickering luster may be seen.
As for its boiling point, it is about a certain temperature range. Due to the force between molecules, its boiling point can be maintained at a specific value. The existence of this value makes it change from liquid to gas at a specific temperature. The characteristics of this boiling point are crucial in the experimental operation of separation and purification.
In terms of melting point, there are also specific values. When the temperature drops below the melting point, the substance will solidify from liquid to solid, and the molecular arrangement will gradually become orderly from disorder, forming a regular lattice structure.
In terms of solubility, 4- (bromomethyl) -1-chloro-2-fluorobenzene exhibits good solubility in organic solvents, such as common ether, dichloromethane, etc. Due to the electronegativity of each atom in the molecular structure, it has a certain polarity, and can form interactions such as van der Waals forces with organic solvent molecules, so it can be fused. However, in water, its solubility is poor. Water is a strong polar solvent, and the interaction with the compound molecules is weak, making it difficult to dissolve in water.
Density is also one of its important physical properties. Its density is higher than that of water, so if it is mixed with water and left to stand, it will sink to the bottom. This property can be used in some processes involving liquid-liquid separation.
In addition, its vapor pressure cannot be ignored. At a certain temperature, the vapor pressure of this substance determines the degree of difficulty in volatilization. The higher the vapor pressure, the more easily it will evaporate into the gas phase under the same conditions. During storage and use, attention should be paid to prevent excessive evaporation from causing losses or causing safety problems.
What are the synthesis methods of 4- (bromomethyl) -1-chloro-2-fluorobenzene
There are several common methods for synthesizing 4- (bromomethyl) -1 -chloro-2 -fluorobenzene. First, it can be started by the corresponding halogenated aromatic hydrocarbon. First, take a benzene derivative containing chlorine and fluorine, introduce methyl under appropriate reaction conditions, and the methyl is converted into bromomethyl by a specific reagent. In this process, it is crucial to choose an appropriate reaction solvent and catalyst. For example, an organic solvent is used as the reaction medium, and a specific metal salt is added as the catalyst to promote the reaction to proceed in the direction of the target product.
Furthermore, it can be achieved by a nucleophilic substitution reaction. A benzene halide containing chlorine and fluorine is used as the substrate and interacts with a nucleophilic reagent containing bromomethyl. At this time, it is necessary to adjust the reaction temperature, reaction time and other conditions to improve the yield and purity of the product. For example, in a specific temperature range, the two are fully reacted for a certain period of time, and the product is purified by recrystallization or column chromatography.
And aromatic hydrocarbons are used as raw materials to construct target molecules through multi-step reactions. First chlorination and fluorination of aromatic hydrocarbons are carried out to precisely locate the substitution check point. Then methyl is introduced, and then bromination is carried out to convert methyl to bromomethyl. Each step of the reaction requires fine control of the reaction conditions to ensure the smooth progress of each step and reduce the occurrence of side reactions. In this way, through various steps, 4- (bromomethyl) -1-chloro-2-fluorobenzene may be obtained.
Furthermore, it can be achieved by a nucleophilic substitution reaction. A benzene halide containing chlorine and fluorine is used as the substrate and interacts with a nucleophilic reagent containing bromomethyl. At this time, it is necessary to adjust the reaction temperature, reaction time and other conditions to improve the yield and purity of the product. For example, in a specific temperature range, the two are fully reacted for a certain period of time, and the product is purified by recrystallization or column chromatography.
And aromatic hydrocarbons are used as raw materials to construct target molecules through multi-step reactions. First chlorination and fluorination of aromatic hydrocarbons are carried out to precisely locate the substitution check point. Then methyl is introduced, and then bromination is carried out to convert methyl to bromomethyl. Each step of the reaction requires fine control of the reaction conditions to ensure the smooth progress of each step and reduce the occurrence of side reactions. In this way, through various steps, 4- (bromomethyl) -1-chloro-2-fluorobenzene may be obtained.
4- (bromomethyl) -1-chloro-2-fluorobenzene what to pay attention to when storing and transporting
4- (bromomethyl) -1-chloro-2-fluorobenzene is one of the organic compounds. During storage and transportation, more attention should be paid.
Bear the brunt, because of its chemical activity, it must be placed in a cool, dry and well-ventilated place. This is to avoid chemical reactions and deterioration of substances due to temperature and humidity. If it is placed in a high temperature and humid place, it may promote hydrolysis, polymerization and other reactions, which will damage its quality and purity.
Furthermore, this compound may be toxic and corrosive to a certain extent, so the storage container must be strictly selected. It is advisable to use corrosion-resistant materials, such as glass, certain plastics or metal containers, and seal them tightly to prevent leakage. Once leaked, it will not only endanger the surrounding environment, but also pose a great danger to personnel.
When transporting, there are also many precautions. It is necessary to properly pack in accordance with relevant regulations. The packaging materials used should be able to resist vibration and collision to ensure safety during transportation. And the transportation tools should also maintain suitable temperature and humidity conditions to avoid severe turbulence.
In addition, people who come into contact with this compound must have complete protective measures. Such as wearing protective clothing, protective gloves and goggles to prevent inadvertent contact and injury to the body.
In conclusion, the storage and transportation of 4- (bromomethyl) -1 -chloro-2 -fluorobenzene must be carried out with care and in accordance with regulations to ensure the safety of personnel and the integrity of the material.
Bear the brunt, because of its chemical activity, it must be placed in a cool, dry and well-ventilated place. This is to avoid chemical reactions and deterioration of substances due to temperature and humidity. If it is placed in a high temperature and humid place, it may promote hydrolysis, polymerization and other reactions, which will damage its quality and purity.
Furthermore, this compound may be toxic and corrosive to a certain extent, so the storage container must be strictly selected. It is advisable to use corrosion-resistant materials, such as glass, certain plastics or metal containers, and seal them tightly to prevent leakage. Once leaked, it will not only endanger the surrounding environment, but also pose a great danger to personnel.
When transporting, there are also many precautions. It is necessary to properly pack in accordance with relevant regulations. The packaging materials used should be able to resist vibration and collision to ensure safety during transportation. And the transportation tools should also maintain suitable temperature and humidity conditions to avoid severe turbulence.
In addition, people who come into contact with this compound must have complete protective measures. Such as wearing protective clothing, protective gloves and goggles to prevent inadvertent contact and injury to the body.
In conclusion, the storage and transportation of 4- (bromomethyl) -1 -chloro-2 -fluorobenzene must be carried out with care and in accordance with regulations to ensure the safety of personnel and the integrity of the material.
What are the effects of 4- (bromomethyl) -1-chloro-2-fluorobenzene on the environment and human health
4- (bromomethyl) -1 -chloro-2 -fluorobenzene is also an organic compound. This substance has an impact on the environment and human health.
First of all, its impact on the environment. If it is released in the environment, or transported and transformed between water bodies, soils, and atmospheres. In water bodies, because of its hydrophobicity, or adsorption on suspended particles, it settles to the bottom of the water, affecting aquatic ecology. Contact with aquatic organisms may cause growth and reproduction to be hindered. For example, fish may have abnormal development, resulting in changes in population numbers. In the soil, or affect the structure and function of the soil microbial community, interfere with the normal material circulation and energy conversion of the soil, such as inhibiting the activity of some microorganisms involved in the nitrogen cycle, so that soil fertility is affected. If this substance is contained in the atmosphere, it will undergo photochemical reactions or produce harmful secondary pollutants, which will deteriorate air quality.
On its impact on human health. There are many ways of human contact, which can be inhaled through the respiratory tract, skin contact and digestive tract. Inhalation of air containing this substance may irritate the respiratory tract, causing cough, asthma and other symptoms. Long-term inhalation may damage lung function and increase the risk of respiratory diseases. Skin contact may cause skin allergies, redness, swelling, itching, etc. If ingested through the digestive tract, or accumulated in the body, it will damage the liver, kidneys and other organs. Because it contains halogen atoms, or interferes with the human endocrine system, affects the balance of hormones, and causes adverse consequences for reproduction and development, such as affecting the normal development of the fetus and increasing the incidence of reproductive system diseases.
In summary, 4- (bromomethyl) -1-chloro-2-fluorobenzene poses a potential threat to the environment and human health. During its production, use and disposal, it should be treated with caution and effective prevention and control measures should be taken to reduce its harm.
First of all, its impact on the environment. If it is released in the environment, or transported and transformed between water bodies, soils, and atmospheres. In water bodies, because of its hydrophobicity, or adsorption on suspended particles, it settles to the bottom of the water, affecting aquatic ecology. Contact with aquatic organisms may cause growth and reproduction to be hindered. For example, fish may have abnormal development, resulting in changes in population numbers. In the soil, or affect the structure and function of the soil microbial community, interfere with the normal material circulation and energy conversion of the soil, such as inhibiting the activity of some microorganisms involved in the nitrogen cycle, so that soil fertility is affected. If this substance is contained in the atmosphere, it will undergo photochemical reactions or produce harmful secondary pollutants, which will deteriorate air quality.
On its impact on human health. There are many ways of human contact, which can be inhaled through the respiratory tract, skin contact and digestive tract. Inhalation of air containing this substance may irritate the respiratory tract, causing cough, asthma and other symptoms. Long-term inhalation may damage lung function and increase the risk of respiratory diseases. Skin contact may cause skin allergies, redness, swelling, itching, etc. If ingested through the digestive tract, or accumulated in the body, it will damage the liver, kidneys and other organs. Because it contains halogen atoms, or interferes with the human endocrine system, affects the balance of hormones, and causes adverse consequences for reproduction and development, such as affecting the normal development of the fetus and increasing the incidence of reproductive system diseases.
In summary, 4- (bromomethyl) -1-chloro-2-fluorobenzene poses a potential threat to the environment and human health. During its production, use and disposal, it should be treated with caution and effective prevention and control measures should be taken to reduce its harm.
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