Linshang Chemical
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4-Chloro-1,2-Diamino-5-Fluorobenzene
Linshang Chemical
|
HS Code |
159937 |
| Chemical Formula | C6H6ClFN2 |
| Molar Mass | 160.577 g/mol |
| Appearance | Solid (usually white to off - white) |
| Odor | May have a characteristic chemical odor |
| Solubility In Water | Low solubility in water |
| Solubility In Organic Solvents | Soluble in some organic solvents like ethanol, acetone |
| Melting Point | Specific melting point data would need to be sourced from literature |
| Boiling Point | Specific boiling point data would need to be sourced from literature |
| Density | Density data would need to be sourced from literature |
| Pka | Acid - base properties data (pKa) would need to be sourced from literature |
| Stability | Stable under normal conditions if stored properly, but may react with strong oxidizing agents |
As an accredited 4-Chloro-1,2-Diamino-5-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 4 - chloro - 1,2 - diamino - 5 - fluorobenzene packaged in a sealed plastic bottle. |
| Storage | 4 - chloro - 1,2 - diamino - 5 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and direct sunlight. Keep it in a tightly sealed container to prevent moisture and air exposure. Store it separately from oxidizing agents and acids to avoid potential chemical reactions. Adhere to safety regulations and label containers clearly. |
| Shipping | 4 - chloro - 1,2 - diamino - 5 - fluorobenzene is shipped in well - sealed, corrosion - resistant containers. Transport follows strict chemical safety regulations to prevent leakage, ensuring safe transit to the destination. |
Competitive 4-Chloro-1,2-Diamino-5-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Chloro-1,2-Diamino-5-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 4-chloro-1,2-diamino-5-fluorobenzene?
4-Chloro-1,2-diamino-5-fluorobenzene is a kind of organic compound. Its main use is very important in today's field of organic synthesis.
First of all, it is often the key intermediate for the preparation of various fine chemicals. In the process of pharmaceutical chemistry, it can be transformed through a series of delicate transformations to obtain drug molecules with unique pharmacological activities. For example, by means of organic synthesis, it can be combined with specific functional groups, or its structure can be modified to obtain compounds with therapeutic effects on specific diseases. This is because of the unique activity and reactivity of chlorine, fluorine, amino and other functional groups in its structure, which can interact with targets in organisms, laying the foundation for the creation of new drugs.
Furthermore, in the field of materials science, it also has its uses. It can participate in the synthesis of polymer materials with special properties. Due to its special structure, it can endow materials with good stability, conductivity or optical properties. For example, in the preparation of some functional polymers, the introduction of 4-chloro-1,2-diamino-5-fluorobenzene structural units can regulate the electron cloud distribution of polymers, and then change their electrical and optical behaviors to meet the special needs of different fields for material properties.
Again, in the field of pesticide chemistry, it can be used as an important starting material for the construction of high-efficiency and low-toxicity pesticides. After chemical modification, the synthesized compound can exhibit excellent biological activity against specific pests or pathogens, and is environmentally friendly, in line with the current trend of green pesticide development. Because of its fluorine, chlorine and other elements, it can enhance the lipophilicity and stability of the compound, and help improve the shelf life and efficacy of pesticides.
From this perspective, 4-chloro-1,2-diamino-5-fluorobenzene has important uses in many fields such as organic synthesis, medicine, materials and pesticides, and plays an indispensable role in promoting the development of various fields.
First of all, it is often the key intermediate for the preparation of various fine chemicals. In the process of pharmaceutical chemistry, it can be transformed through a series of delicate transformations to obtain drug molecules with unique pharmacological activities. For example, by means of organic synthesis, it can be combined with specific functional groups, or its structure can be modified to obtain compounds with therapeutic effects on specific diseases. This is because of the unique activity and reactivity of chlorine, fluorine, amino and other functional groups in its structure, which can interact with targets in organisms, laying the foundation for the creation of new drugs.
Furthermore, in the field of materials science, it also has its uses. It can participate in the synthesis of polymer materials with special properties. Due to its special structure, it can endow materials with good stability, conductivity or optical properties. For example, in the preparation of some functional polymers, the introduction of 4-chloro-1,2-diamino-5-fluorobenzene structural units can regulate the electron cloud distribution of polymers, and then change their electrical and optical behaviors to meet the special needs of different fields for material properties.
Again, in the field of pesticide chemistry, it can be used as an important starting material for the construction of high-efficiency and low-toxicity pesticides. After chemical modification, the synthesized compound can exhibit excellent biological activity against specific pests or pathogens, and is environmentally friendly, in line with the current trend of green pesticide development. Because of its fluorine, chlorine and other elements, it can enhance the lipophilicity and stability of the compound, and help improve the shelf life and efficacy of pesticides.
From this perspective, 4-chloro-1,2-diamino-5-fluorobenzene has important uses in many fields such as organic synthesis, medicine, materials and pesticides, and plays an indispensable role in promoting the development of various fields.
4-Chloro-1, what are the physical properties of 2-diamino-5-fluorobenzene
4-Chloro-1,2-diamino-5-fluorobenzene is a kind of organic compound. Its physical properties are as follows:
Under normal temperature and pressure, it is mostly in a solid state. Due to the strong force between molecules, it has a relatively stable aggregate state. Its color may be white to white-like powder. The formation of this color state is related to the absorption and reflection characteristics of the molecular structure. The arrangement and combination of various atoms and chemical bonds in the molecular structure determines its effect on different wavelengths of light, resulting in a specific color.
In terms of its melting point, it has been experimentally determined to be in a certain temperature range. The melting point is closely related to the intermolecular force. There are amino groups, chlorine atoms, fluorine atoms, etc., in the molecule. These groups interact with each other through hydrogen bonds, van der Waals forces, etc., so that the molecules are closely bound. High energy is required to overcome this force and realize the transition from solid to liquid.
As for solubility, this compound can have a certain solubility in organic solvents, such as some alcohols and ether solvents. Some groups in its molecular structure have the characteristics of organic solvents, and can form interactions with solvent molecules, such as hydrogen bonds, van der Waals forces, etc., so that it can be dispersed in solvents. However, the solubility in water is poor, due to the strong polarity of water molecules, and the overall polarity of the compound is not enough to form a strong enough interaction with water molecules, so it is difficult to dissolve in water.
Its density is also an important physical property, and specific values can be obtained by precise measurement. The density reflects the degree of intermolecular compactness and atomic mass distribution. Compared with similar compounds, the characteristics of its molecular structure, such as atomic type, number and spatial arrangement, can be used to analyze the reasons for the difference in density.
In summary, the physical properties of 4-chloro-1,2-diamino-5-fluorobenzene are closely related to its unique molecular structure, and these properties are of great significance in many fields such as chemical synthesis and materials science, providing a solid foundation for its application and research.
Under normal temperature and pressure, it is mostly in a solid state. Due to the strong force between molecules, it has a relatively stable aggregate state. Its color may be white to white-like powder. The formation of this color state is related to the absorption and reflection characteristics of the molecular structure. The arrangement and combination of various atoms and chemical bonds in the molecular structure determines its effect on different wavelengths of light, resulting in a specific color.
In terms of its melting point, it has been experimentally determined to be in a certain temperature range. The melting point is closely related to the intermolecular force. There are amino groups, chlorine atoms, fluorine atoms, etc., in the molecule. These groups interact with each other through hydrogen bonds, van der Waals forces, etc., so that the molecules are closely bound. High energy is required to overcome this force and realize the transition from solid to liquid.
As for solubility, this compound can have a certain solubility in organic solvents, such as some alcohols and ether solvents. Some groups in its molecular structure have the characteristics of organic solvents, and can form interactions with solvent molecules, such as hydrogen bonds, van der Waals forces, etc., so that it can be dispersed in solvents. However, the solubility in water is poor, due to the strong polarity of water molecules, and the overall polarity of the compound is not enough to form a strong enough interaction with water molecules, so it is difficult to dissolve in water.
Its density is also an important physical property, and specific values can be obtained by precise measurement. The density reflects the degree of intermolecular compactness and atomic mass distribution. Compared with similar compounds, the characteristics of its molecular structure, such as atomic type, number and spatial arrangement, can be used to analyze the reasons for the difference in density.
In summary, the physical properties of 4-chloro-1,2-diamino-5-fluorobenzene are closely related to its unique molecular structure, and these properties are of great significance in many fields such as chemical synthesis and materials science, providing a solid foundation for its application and research.
Is 4-chloro-1, 2-diamino-5-fluorobenzene chemically stable?
The stability of the chemical properties of 4-chloro-1,2-diamino-5-fluorobenzene depends on multiple factors and cannot be generalized.
As far as its structure is concerned, the benzene ring has a certain stability, but the chlorine, fluorine, amino and other groups connected to it have an impact on its stability. Chlorine and fluorine are both halogen elements and have electron-withdrawing properties. Fluorine is extremely electronegative, and chlorine also has considerable electron-withdrawing ability. The connection of the two to the benzene ring will reduce the electron cloud density of the benzene ring, causing the benzene ring to be relatively more prone to electrophilic substitution reactions. From this perspective, the stability is weakened.
Furthermore, the amino group is the power supply group, which can increase the electron cloud density of the benzene ring and enhance the stability of the benzene ring. However, at the same time, there are lone pairs of electrons on the nitrogen atom of the amino group, which are easy to interact with other molecules, or participate in chemical reactions, such as salts with acids, etc., and may affect its stability.
In addition, external conditions also have a great impact on its stability. If it is in a high temperature environment, the thermal motion of the molecule intensifies, the vibration of the chemical bond is enhanced, and it is easy to cause the chemical bond to break, which will reduce the stability. In case of strong oxidizing agents or reducing agents, due to the activity of each group in the structure of the substance, oxidation and reduction reactions are prone to occur, and stability is difficult to maintain. Under light conditions, photochemical reactions may be
Overall, the chemical stability of 4-chloro-1,2-diamino-5-fluorobenzene requires comprehensive consideration of structural characteristics and external conditions. Under different scenarios, the stability performance varies, and it is impossible to simply determine its stability or instability.
As far as its structure is concerned, the benzene ring has a certain stability, but the chlorine, fluorine, amino and other groups connected to it have an impact on its stability. Chlorine and fluorine are both halogen elements and have electron-withdrawing properties. Fluorine is extremely electronegative, and chlorine also has considerable electron-withdrawing ability. The connection of the two to the benzene ring will reduce the electron cloud density of the benzene ring, causing the benzene ring to be relatively more prone to electrophilic substitution reactions. From this perspective, the stability is weakened.
Furthermore, the amino group is the power supply group, which can increase the electron cloud density of the benzene ring and enhance the stability of the benzene ring. However, at the same time, there are lone pairs of electrons on the nitrogen atom of the amino group, which are easy to interact with other molecules, or participate in chemical reactions, such as salts with acids, etc., and may affect its stability.
In addition, external conditions also have a great impact on its stability. If it is in a high temperature environment, the thermal motion of the molecule intensifies, the vibration of the chemical bond is enhanced, and it is easy to cause the chemical bond to break, which will reduce the stability. In case of strong oxidizing agents or reducing agents, due to the activity of each group in the structure of the substance, oxidation and reduction reactions are prone to occur, and stability is difficult to maintain. Under light conditions, photochemical reactions may be
Overall, the chemical stability of 4-chloro-1,2-diamino-5-fluorobenzene requires comprehensive consideration of structural characteristics and external conditions. Under different scenarios, the stability performance varies, and it is impossible to simply determine its stability or instability.
What is the preparation method of 4-chloro-1,2-diamino-5-fluorobenzene
The preparation method of 4-chloro-1,2-diamino-5-fluorobenzene, although the ancient book "Tiangong Kaiwu" does not contain this specific compound preparation method, it can be deduced according to the chemical preparation ideas of the ancients.
In the past, the preparation of such aromatic compounds containing specific substituents may begin with the choice of raw materials. Compounds containing benzene rings and which can be converted into target substituents can be found as starting materials. For example, nitrobenzene containing chlorine and fluorine substitutions is used as raw materials, because the nitro group is easily reduced to an amino group.
Take the appropriate 4-chloro-5-fluoronitrobenzene first, and the chlorine and fluorine in this raw material are already at specific positions in the benzene ring. Placing it in a suitable reduction system, the ancients used a combination of metal and acid, such as iron and hydrochloric acid. The interaction of iron and hydrochloric acid produces new hydrogen, which can gradually reduce the nitro group to an amino group, and go through the intermediate nitroso and hydroxylamine groups to obtain 4-chloro-1,2-diamino-5-fluorobenzene. Pay attention to the ratio of temperature to reactants during the reaction. If the temperature is too high or the ratio is improper, it is easy to cause side reactions to occur and the product is impure.
Or prepare benzene containing amino groups and chlorine first, and then introduce fluorine atoms. Chlorine atoms can be introduced by a suitable nucleophilic substitution reagent through diazotization reaction starting from aniline derivatives. Then, using fluorine-containing reagents, such as potassium fluoride, under specific conditions, fluorine atoms are introduced into the appropriate position of the benzene ring, and finally the nitro group is reduced to obtain the target product. In this process, the control of reaction conditions at each step is very important. Diazotization requires low temperature, and nucleophilic substitution requires suitable solvents and bases to obtain 4-chloro-1,2-diamino-5-fluorobenzene with high yield and purity.
In the past, the preparation of such aromatic compounds containing specific substituents may begin with the choice of raw materials. Compounds containing benzene rings and which can be converted into target substituents can be found as starting materials. For example, nitrobenzene containing chlorine and fluorine substitutions is used as raw materials, because the nitro group is easily reduced to an amino group.
Take the appropriate 4-chloro-5-fluoronitrobenzene first, and the chlorine and fluorine in this raw material are already at specific positions in the benzene ring. Placing it in a suitable reduction system, the ancients used a combination of metal and acid, such as iron and hydrochloric acid. The interaction of iron and hydrochloric acid produces new hydrogen, which can gradually reduce the nitro group to an amino group, and go through the intermediate nitroso and hydroxylamine groups to obtain 4-chloro-1,2-diamino-5-fluorobenzene. Pay attention to the ratio of temperature to reactants during the reaction. If the temperature is too high or the ratio is improper, it is easy to cause side reactions to occur and the product is impure.
Or prepare benzene containing amino groups and chlorine first, and then introduce fluorine atoms. Chlorine atoms can be introduced by a suitable nucleophilic substitution reagent through diazotization reaction starting from aniline derivatives. Then, using fluorine-containing reagents, such as potassium fluoride, under specific conditions, fluorine atoms are introduced into the appropriate position of the benzene ring, and finally the nitro group is reduced to obtain the target product. In this process, the control of reaction conditions at each step is very important. Diazotization requires low temperature, and nucleophilic substitution requires suitable solvents and bases to obtain 4-chloro-1,2-diamino-5-fluorobenzene with high yield and purity.
What is the price range of 4-chloro-1,2-diamino-5-fluorobenzene in the market?
I don't know the price range of 4-chloro-1,2-diamino-5-fluorobenzene in the market. The price of these products often varies due to various reasons, such as quality, quantity purchased, supply and demand in the market, cost of production and differences between sellers. To know the exact price, it is recommended to consult the chemical raw material market, chemical reagent suppliers, or check the chemical-related e-commerce platform to get a near-real price. Due to the lack of exact market information, it is difficult to determine the price range.
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