Linshang Chemical
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4-Chloro-1,2-Diaminobenzene
Linshang Chemical
|
HS Code |
511320 |
| Name | 4-Chloro-1,2-Diaminobenzene |
| Chemical Formula | C6H7ClN2 |
| Molar Mass | 142.59 g/mol |
| Appearance | Pale yellow to brownish solid |
| Melting Point | 98 - 100 °C |
| Boiling Point | 285 - 287 °C |
| Solubility In Water | Slightly soluble |
| Solubility In Organic Solvents | Soluble in ethanol, ether, etc. |
| Density | 1.315 g/cm³ |
| Flash Point | 141.7 °C |
| Odor | Characteristic amine - like odor |
| Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 4-Chloro-1,2-Diaminobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - chloro - 1,2 - diaminobenzene packaged in a sealed, chemical - resistant bag. |
| Storage | 4 - chloro - 1,2 - diaminobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture and air exposure, which could lead to decomposition or oxidation. Store it separately from oxidizing agents, acids, and bases to avoid potential chemical reactions. |
| Shipping | 4 - chloro - 1,2 - diaminobenzene, a potentially hazardous chemical, is shipped in well - sealed, corrosion - resistant containers. Strict safety protocols are followed, with proper labeling indicating its nature for secure transportation. |
Competitive 4-Chloro-1,2-Diaminobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Chloro-1,2-Diaminobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 4-chloro-1,2-diaminobenzene?
4-Chloro-1,2-diaminobenzene, an organic compound with unique chemical properties. Its appearance is often solid, either powder or crystalline, depending on preparation and purity.
At the end of the chemical activity, the amino group (\ (- NH_ {2}\)) and the chlorine atom (\ (-Cl\)) coexist on the benzene ring, giving it special reactivity. The amino group is an electron-supplying group, which can increase the electron cloud density of the benzene ring and easily initiate an electrophilic substitution reaction. In case of electrophilic reagents, the reaction check point may be mostly in the amino o or para-position. Although the chlorine atom is also in the benzene ring, its electron-absorbing induction effect will affect the reactivity and check point selectivity to a certain extent.
Besides solubility, because of its polar group amino group, it may have a certain solubility in polar solvents such as water, but due to the non-polar structure of the benzene ring, the solubility may be limited. In contrast, in organic solvents such as alcohols and ethers, the solubility may be better.
In terms of stability, 4-chloro-1,2-diaminobenzene is relatively stable at room temperature and pressure. However, in case of high temperature, open flame or strong oxidant, it may be dangerous. Amino groups are easily oxidized, resulting in changes in structure and properties.
In chemical reactions, it can participate in many organic synthesis reactions. For example, amino groups can react with acids to form salts to generate corresponding ammonium salts; they can also react with acyl chloride, acid anhydride, etc. to obtain amide derivatives. Chlorine atoms can participate in nucleophilic substitution reactions and be replaced by other nucleophilic reagents to construct new organic compound structures, which are widely used in the field of organic synthesis.
At the end of the chemical activity, the amino group (\ (- NH_ {2}\)) and the chlorine atom (\ (-Cl\)) coexist on the benzene ring, giving it special reactivity. The amino group is an electron-supplying group, which can increase the electron cloud density of the benzene ring and easily initiate an electrophilic substitution reaction. In case of electrophilic reagents, the reaction check point may be mostly in the amino o or para-position. Although the chlorine atom is also in the benzene ring, its electron-absorbing induction effect will affect the reactivity and check point selectivity to a certain extent.
Besides solubility, because of its polar group amino group, it may have a certain solubility in polar solvents such as water, but due to the non-polar structure of the benzene ring, the solubility may be limited. In contrast, in organic solvents such as alcohols and ethers, the solubility may be better.
In terms of stability, 4-chloro-1,2-diaminobenzene is relatively stable at room temperature and pressure. However, in case of high temperature, open flame or strong oxidant, it may be dangerous. Amino groups are easily oxidized, resulting in changes in structure and properties.
In chemical reactions, it can participate in many organic synthesis reactions. For example, amino groups can react with acids to form salts to generate corresponding ammonium salts; they can also react with acyl chloride, acid anhydride, etc. to obtain amide derivatives. Chlorine atoms can participate in nucleophilic substitution reactions and be replaced by other nucleophilic reagents to construct new organic compound structures, which are widely used in the field of organic synthesis.
What are the main uses of 4-chloro-1,2-diaminobenzene?
4-Chloro-1,2-diaminobenzene has a wide range of uses in the chemical industry. First, it can be used as a raw material for dye synthesis. The production of dyes requires a variety of fine chemicals. This substance can participate in it, and through various reactions, the dye can obtain a specific color and performance. Because of the presence of chlorine atoms and amino groups in its structure, it can play a unique role in the reaction, helping the dye molecules to form a stable structure and show rich colors. It is of great significance in textile printing and dyeing and other industries, and can give the fabric a bright and lasting color.
Second, it is also useful in the field of medicinal chemistry. Can be used as an intermediate in the synthesis of certain drugs. Drug synthesis, such as Guangsha, is made up of many basic components, 4-chloro-1,2-diaminobenzene can be one of the key components. Through chemical modification and reaction, it is connected to the molecular framework of the drug to endow the drug with specific pharmacological activity to achieve the purpose of treating diseases.
Furthermore, in the field of materials science, it may be used to synthesize special polymer materials. Because it contains active amino groups and chlorine atoms, it can participate in polymerization reactions to build unique polymer structures, so that the material has special properties, such as excellent mechanical properties, thermal stability or electrical conductivity, etc., and may have potential applications in fields such as electronics and aerospace that require strict material properties. In conclusion, 4-chloro-1,2-diaminobenzene, with its unique chemical structure, has been used in various fields such as dyes, medicine, and materials, and has promoted various industrial development and scientific and technological progress.
Second, it is also useful in the field of medicinal chemistry. Can be used as an intermediate in the synthesis of certain drugs. Drug synthesis, such as Guangsha, is made up of many basic components, 4-chloro-1,2-diaminobenzene can be one of the key components. Through chemical modification and reaction, it is connected to the molecular framework of the drug to endow the drug with specific pharmacological activity to achieve the purpose of treating diseases.
Furthermore, in the field of materials science, it may be used to synthesize special polymer materials. Because it contains active amino groups and chlorine atoms, it can participate in polymerization reactions to build unique polymer structures, so that the material has special properties, such as excellent mechanical properties, thermal stability or electrical conductivity, etc., and may have potential applications in fields such as electronics and aerospace that require strict material properties. In conclusion, 4-chloro-1,2-diaminobenzene, with its unique chemical structure, has been used in various fields such as dyes, medicine, and materials, and has promoted various industrial development and scientific and technological progress.
What is the production method of 4-chloro-1,2-diaminobenzene?
The preparation method of 4-chloro-1,2-diaminobenzene has been studied by many ancient Fang families. The first method is to start with o-nitrochlorobenzene, and first through the reduction technique to obtain o-chloroaniline. This reduction method often uses iron powder and hydrochloric acid to react together, just like the ancients in alchemy. With the simplicity of iron and the agility of hydrochloric acid, the two are combined to make the nitro group into an amino group, and then o-chloroaniline is obtained.
Then, o-chloroaniline needs to be nitrified again. This unusual move of nitrification requires a mixture of concentrated nitric acid and concentrated sulfuric acid, such as adjusting the pot, and carefully controlling the temperature and ratio. 4-Chloro-2-nitroaniline is obtained by adding o-chloroaniline to this mixed acid, and ingeniously guiding the nitro group into the appropriate position. In this step, the reaction situation needs to be carefully observed. If there is a slight difference, the product will be impure.
After obtaining 4-chloro-2-nitroaniline, a secondary reduction is required. This time, a reducing agent such as sodium sulfide can be used to reproduce the nitro group into an amino group with mild force, and finally 4-chloro-1,2-diaminobenzene. This process is like a step-by-step climb, and each step needs to be carefully handled to obtain a pure product.
There are other methods, starting with o-phenylenediamine. O-phenylenediamine meets the chlorine source, the chlorine source may be a chlorination reagent, and the two interact. Like yin and yang, the chlorine atom is cleverly connected to the benzene ring, and 4-chloro-1,2-diaminobenzene can also be obtained under suitable reaction conditions, such as controlling temperature and duration. However, this path also needs to pay attention to the side effects of the reaction to avoid its misdirection, so that the product can be produced smoothly.
Then, o-chloroaniline needs to be nitrified again. This unusual move of nitrification requires a mixture of concentrated nitric acid and concentrated sulfuric acid, such as adjusting the pot, and carefully controlling the temperature and ratio. 4-Chloro-2-nitroaniline is obtained by adding o-chloroaniline to this mixed acid, and ingeniously guiding the nitro group into the appropriate position. In this step, the reaction situation needs to be carefully observed. If there is a slight difference, the product will be impure.
After obtaining 4-chloro-2-nitroaniline, a secondary reduction is required. This time, a reducing agent such as sodium sulfide can be used to reproduce the nitro group into an amino group with mild force, and finally 4-chloro-1,2-diaminobenzene. This process is like a step-by-step climb, and each step needs to be carefully handled to obtain a pure product.
There are other methods, starting with o-phenylenediamine. O-phenylenediamine meets the chlorine source, the chlorine source may be a chlorination reagent, and the two interact. Like yin and yang, the chlorine atom is cleverly connected to the benzene ring, and 4-chloro-1,2-diaminobenzene can also be obtained under suitable reaction conditions, such as controlling temperature and duration. However, this path also needs to pay attention to the side effects of the reaction to avoid its misdirection, so that the product can be produced smoothly.
What are the precautions for 4-chloro-1,2-diaminobenzene in storage and transportation?
4-Chloro-1,2-diaminobenzene is also a chemical substance. When storing and transporting, many things need to be paid attention to.
First words storage, this substance should be placed in a cool and ventilated warehouse. Because of the cool and ventilated place, it can reduce the risk of changes due to excessive temperature and poor air. And keep away from fire and heat sources to prevent fire or chemical reactions. The lighting, ventilation and other facilities of the warehouse should be explosion-proof, and the switch should also be located outside the warehouse, so as to avoid the spark caused by electrical equipment and cause the substance to explode. At the same time, it should be stored separately from oxidizing agents, acids, etc., and must not be mixed. If it reacts violently with their substances, it will be dangerous. For storage containers, it is necessary to ensure that they are well sealed to prevent them from leaking into the air, causing environmental pollution, and preventing them from deteriorating due to contact with air components.
As for transportation, it is necessary to ensure that the packaging is complete and safely loaded before transportation. Packaging materials must be able to withstand a certain amount of external force to prevent substances from leaking during transportation. During transportation, the speed should not be too fast, and sudden braking should be avoided to prevent package damage due to bumps and collisions. Transportation vehicles should be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment to prepare for emergencies. In the event of a leak during transportation, drivers and passengers must take immediate emergency measures to evacuate the surrounding crowd, seal off the scene, and report to the relevant departments in a timely manner. And vehicles transporting the substance shall not be transported with the above-mentioned contraindications to ensure transportation safety.
All of these are important matters that should not be ignored when storing and transporting 4-chloro-1,2-diaminobenzene, and should be treated with caution to avoid dangerous accidents.
First words storage, this substance should be placed in a cool and ventilated warehouse. Because of the cool and ventilated place, it can reduce the risk of changes due to excessive temperature and poor air. And keep away from fire and heat sources to prevent fire or chemical reactions. The lighting, ventilation and other facilities of the warehouse should be explosion-proof, and the switch should also be located outside the warehouse, so as to avoid the spark caused by electrical equipment and cause the substance to explode. At the same time, it should be stored separately from oxidizing agents, acids, etc., and must not be mixed. If it reacts violently with their substances, it will be dangerous. For storage containers, it is necessary to ensure that they are well sealed to prevent them from leaking into the air, causing environmental pollution, and preventing them from deteriorating due to contact with air components.
As for transportation, it is necessary to ensure that the packaging is complete and safely loaded before transportation. Packaging materials must be able to withstand a certain amount of external force to prevent substances from leaking during transportation. During transportation, the speed should not be too fast, and sudden braking should be avoided to prevent package damage due to bumps and collisions. Transportation vehicles should be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment to prepare for emergencies. In the event of a leak during transportation, drivers and passengers must take immediate emergency measures to evacuate the surrounding crowd, seal off the scene, and report to the relevant departments in a timely manner. And vehicles transporting the substance shall not be transported with the above-mentioned contraindications to ensure transportation safety.
All of these are important matters that should not be ignored when storing and transporting 4-chloro-1,2-diaminobenzene, and should be treated with caution to avoid dangerous accidents.
What are the effects of 4-chloro-1,2-diaminobenzene on the environment and human health?
4-Chloro-1,2-diaminobenzene, which is very important to the environment and human health.
It can cause pollution to the environment if it flows into natural water bodies or soils. In water bodies, it may interfere with the normal life of aquatic organisms. Aquatic organisms are extremely sensitive to environmental changes, and 4-chloro-1,2-diaminobenzene may affect their growth, reproduction, and even cause their death. If accumulated in the food chain, it can be transmitted layer by layer from microplankton to large fish, or cause damage to the balance of the entire aquatic ecosystem. In the soil, or change the chemical properties of the soil, affect the activity of soil microorganisms, hinder the absorption of nutrients by plant roots, and then affect the growth and development of plants.
As for human health, 4-chloro-1,2-diaminobenzene may be potentially harmful. It may have certain toxicity and enter the human body through breathing, skin contact or accidental ingestion. If breathed, it will irritate the respiratory tract, cause cough, asthma and other discomfort. Skin contact, or cause allergic reactions, such as redness, swelling, itching, etc. Long-term exposure or ingestion, or cause damage to human organs, such as liver, kidneys, because of human body weight to detoxify and metabolic organs, or affected by 4-chloro-1,2-diaminobenzene, resulting in abnormal function. What's more, there may be a carcinogenic risk. Although there is no conclusive conclusion, it is inferred from the study of its chemical structure and similar substances that this risk should not be underestimated. Therefore, 4-chloro-1,2-diaminobenzene should be handled with caution to avoid adverse effects on the environment and human health.
It can cause pollution to the environment if it flows into natural water bodies or soils. In water bodies, it may interfere with the normal life of aquatic organisms. Aquatic organisms are extremely sensitive to environmental changes, and 4-chloro-1,2-diaminobenzene may affect their growth, reproduction, and even cause their death. If accumulated in the food chain, it can be transmitted layer by layer from microplankton to large fish, or cause damage to the balance of the entire aquatic ecosystem. In the soil, or change the chemical properties of the soil, affect the activity of soil microorganisms, hinder the absorption of nutrients by plant roots, and then affect the growth and development of plants.
As for human health, 4-chloro-1,2-diaminobenzene may be potentially harmful. It may have certain toxicity and enter the human body through breathing, skin contact or accidental ingestion. If breathed, it will irritate the respiratory tract, cause cough, asthma and other discomfort. Skin contact, or cause allergic reactions, such as redness, swelling, itching, etc. Long-term exposure or ingestion, or cause damage to human organs, such as liver, kidneys, because of human body weight to detoxify and metabolic organs, or affected by 4-chloro-1,2-diaminobenzene, resulting in abnormal function. What's more, there may be a carcinogenic risk. Although there is no conclusive conclusion, it is inferred from the study of its chemical structure and similar substances that this risk should not be underestimated. Therefore, 4-chloro-1,2-diaminobenzene should be handled with caution to avoid adverse effects on the environment and human health.
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