4-Chloro-1,2-Dimethylbenzene
Linshang Chemical
HS Code |
461058 |
Chemical Formula | C8H9Cl |
Molar Mass | 140.61 g/mol |
Appearance | Colorless to light yellow liquid |
Odor | Aromatic odor |
Density | 1.069 g/cm³ (at 20 °C) |
Boiling Point | 193 - 194 °C |
Melting Point | -34.4 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in ethanol, ether, etc. |
Flash Point | 73 °C |
Vapor Pressure | 0.13 kPa (at 25.2 °C) |
As an accredited 4-Chloro-1,2-Dimethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500 - gram bottle of 4 - chloro - 1,2 - dimethylbenzene, well - sealed for chemical storage. |
Storage | 4 - chloro - 1,2 - dimethylbenzene should be stored in a cool, well - ventilated area, away from heat and ignition sources. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. Ensure storage facilities are designed to prevent spills, and label containers clearly for easy identification. |
Shipping | 4 - chloro - 1,2 - dimethylbenzene is shipped in tightly - sealed, corrosion - resistant containers. They are transported via appropriate carriers, following strict regulations for hazardous chemicals to ensure safe delivery. |
Competitive 4-Chloro-1,2-Dimethylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 4-Chloro-1,2-Dimethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Looking at its physical properties, under room temperature and pressure, 4-chloro-1,2-dimethylbenzene is mostly colorless to light yellow liquid with a special aromatic odor. Its density is slightly higher than that of water, and it is insoluble in water, but it can be miscible with most organic solvents such as ethanol, ether, benzene, etc. This solubility makes it often selected as a solvent or reaction medium in organic synthesis and chemical production.
In terms of chemical properties, in the molecule of 4-chloro-1,2-dimethylbenzene, the chlorine atom interacts with the benzene ring and the methyl group, giving it various reactivity. The electron cloud structure of the benzene ring is affected by the methyl group and the chlorine atom, which changes the electron cloud density at different positions on the benzene ring, thereby affecting the activity and check point selectivity of the electrophilic substitution reaction. Since the methyl group is the power supply group and the chlorine atom is the weak electron-absorbing group, the combined action of the two makes the electron cloud density of the adjacent and para-sites of the benzene ring relatively increase, so the electrophilic substitution reaction easily occurs in the adjacent and para-sites of the benzene ring.
4-chloro-1,2- In the presence of suitable catalysts such as iron filings or ferric chloride, reacting with halogens (such as bromine) can introduce more halogen atoms on the benzene ring to form polyhalogenated products. This reaction mechanism is electrophilic substitution. Bromine generates electrophilic reagents under the action of the catalyst, attacking the position where the electron cloud density of the benzene ring is higher.
It can also participate in the nitrification reaction. Under the action of mixed acid of concentrated sulfuric acid and concentrated nitric acid, nitro groups are introduced into the benzene ring to form nitro-substituted products. This reaction also follows the electrophilic substitution mechanism, and nitro positive ions attack the benzene ring as electrophilic reagents.
In addition, 4-chloro-1,2-dimethylbenzene can also undergo electrophilic substitution reactions such as alkylation and acylation reactions, and is used to construct more complex organic molecular structures in organic synthesis. In addition, the chlorine atoms in the molecule also have certain reactivity, which can undergo substitution reactions under appropriate conditions and be replaced by other functional groups such as hydroxyl and amino groups, thereby deriving a variety of compounds with different functions.
The chemical properties of 4-chloro-1,2-dimethylbenzene are rich and diverse, providing important reaction substrates and intermediates for the field of organic synthesis chemistry, and playing an indispensable role in many fields such as fine chemical products, drug synthesis, and materials science.
Looking at its properties, under room temperature and pressure, 4-chloro-1,2-dimethylbenzene is a colorless to light yellow transparent liquid with a pure and clear appearance. This feature is easy to observe and distinguish during production and use.
When it comes to the boiling point, it is about 193 ° C. The boiling point property is of great significance in chemical operations such as distillation and separation. With the help of the difference in boiling point, 4-chloro-1,2-dimethylbenzene can be effectively separated from other substances to ensure the purity of the product.
In addition, the melting point is about -32 ° C. The melting point determines the temperature at which the substance changes from solid to liquid. When storing and transporting, it is necessary to control the ambient temperature according to the melting point characteristics to prevent it from changing its state due to improper temperature and affecting the quality.
The density of 4-chloro-1,2-dimethylbenzene is about 1.05g/cm ³, which is slightly higher than that of water. This means that in systems involving mixing with water, it will sink to the bottom of the water, which is a guiding property for phase separation operations when treating wastewater containing this substance or performing related reactions.
Its solubility is also worthy of attention. It is slightly soluble in water, but it can be miscible with most organic solvents such as ethanol, ether, acetone, etc. This solubility characteristic facilitates its use as a solvent or participation in reactions in organic synthesis. According to different reaction requirements, suitable organic solvents can be selected to cooperate with it to optimize the reaction process.
In addition, 4-chloro-1,2-dimethylbenzene is volatile and emits a special odor. In the place of use and storage, it is necessary to pay attention to ventilation and ventilation to prevent its volatilization and accumulation, which will cause adverse effects on the environment and human health.
In short, the many physical properties of 4-chloro-1,2-dimethylbenzene are of great significance for its production, storage, transportation and application. In practical operation, these properties need to be fully considered to achieve the purpose of safe and efficient use.
is often used as a key intermediate in the field of organic synthesis. As far as the preparation of pesticides is concerned, it can be converted into pesticide components with specific structures through a series of chemical reactions. Due to the presence of chlorine atoms and methyl groups in the structure, it is endowed with specific reactivity and chemical properties. It can participate in reactions such as nucleophilic substitution and electrophilic substitution to synthesize pesticides with complex structures, kill pests, and ensure crop harvests.
It also plays an important role in the field of pharmaceutical synthesis. Drug molecular structures can be introduced through modification and transformation to improve drug properties. Due to its structural properties, it can affect the solubility, stability and biological activity of drugs, providing the possibility for the creation of new drugs and helping to overcome various diseases.
In addition, in the field of materials science, 4-chloro-1,2-dimethyl benzene also plays a role. After chemical modification, polymer materials with special properties can be synthesized. For example, as a monomer to participate in polymerization reactions to prepare polymers with specific functions, used in electronics, optics and other industries to meet the needs of high-tech development for special materials.
In short, 4-chloro-1,2-dimethyl benzene, with its unique chemical structure, has shown important value in organic synthesis, medicine, materials and other fields, promoting the development and progress of various industries.
First, using o-xylene as the starting material, it can be obtained by chlorination. Under suitable reaction conditions, chlorine gas is used as a chlorination agent. When there is light or a catalyst, chlorine gas reacts with o-xylene. Under light conditions, chlorine atoms easily replace hydrogen atoms on the methyl group of the benzene ring side chain; when catalysts such as ferric chloride act, chlorine atoms mainly replace hydrogen atoms on the benzene ring. Controlling the reaction conditions and the amount of chlorine gas, 4-chloro-1,2-dimethylbenzene can be obtained.
Second, it can be prepared by a series of reactions of reduction, diazotization and chlorination of 1,2-dimethyl-4-nitrobenzene. First, the nitro group in 1,2-dimethyl-4-nitrobenzene is reduced to amino group with appropriate reducing agents, such as iron and hydrochloric acid, etc., to obtain 1,2-dimethyl-4-aniline. Then, 1,2-dimethyl-4-aniline and sodium nitrite undergo diazotization under acidic conditions to form diazonium salts. Finally, using cuprous chloride as a catalyst, the diazonium salt is chlorinated with hydrogen chloride, and the diazonium group is replaced by a chlorine atom to obtain 4-chloro-1,2-dimethylbenzene.
Third, the Grignard reagent method can also be used. React with suitable halogenated aromatics and magnesium to make Grignard reagent, and then react with the corresponding halogenated alkanes or halogenated olefins in suitable solvents and conditions. After subsequent treatment, 4-chloro-1,2-dimethylbenzene can be obtained. However, this method needs to pay attention to the strict control of the reaction conditions to prevent the occurrence of side reactions.
The various methods for synthesizing 4-chloro-1,2-dimethylbenzene have their own advantages and disadvantages. According to actual needs, many factors such as the availability of raw materials, cost, difficulty of reaction conditions, and purity of the product should be considered to choose the appropriate method.
The choice of the first storage environment. This substance should be placed in a cool and ventilated place, away from fire and heat sources. Because the compound is flammable, high temperature or open flame can easily cause combustion, and even cause explosion. The temperature of the warehouse should be controlled within a suitable range, usually not exceeding 30 ° C. At the same time, it is necessary to keep the container sealed to prevent its volatilization from escaping, polluting the environment, and the volatile gas reaches a certain concentration in the air, which is also dangerous in case of open flame.
Furthermore, the layout of the storage site should also be cautious. It should be stored separately from oxidizing agents, acids, alkalis, etc., and must not be mixed. Due to its active chemical properties, contact with these substances or violent chemical reactions can cause accidents. For example, when it encounters with strong oxidizing agents, or an oxidation reaction occurs, a large amount of heat is released, causing the temperature of the system to rise sharply and triggering danger.
When transporting, the packaging must be solid and reliable. Use special packaging materials to ensure that it is not damaged and leaked due to vibration or collision during transportation. Transportation vehicles must also meet safety standards and be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. During transportation, drivers and escorts must have professional knowledge and be familiar with the characteristics of the substance and emergency response methods. When driving, avoid high temperatures and densely populated areas to prevent major casualties and property losses.
In short, the storage and transportation of 4-chloro-1,2-dimethylbenzene is related to the overall safety situation, and all links must be strictly controlled, and relevant norms and requirements must be followed to ensure safety.

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