4-Chloro-1,3-Benzenediamine
Linshang Chemical
HS Code |
188173 |
Chemical Formula | C6H7ClN2 |
Molar Mass | 142.59 g/mol |
Appearance | Solid |
Color | Off - white to light brown |
Melting Point | 127 - 131 °C |
Boiling Point | 305.7 °C at 760 mmHg |
Solubility In Water | Slightly soluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone |
Density | 1.34 g/cm³ |
Odor | Weak, amine - like odor |
Pka | 9.16 (estimated for one of the amino groups) |
As an accredited 4-Chloro-1,3-Benzenediamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 4 - chloro - 1,3 - benzenediamine packaged in a sealed, corrosion - resistant container. |
Storage | 4 - chloro - 1,3 - benzenediamine should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly closed container to prevent moisture absorption and potential reactions. Label the storage container clearly to avoid misidentification. Store separately from incompatible substances to ensure safety. |
Shipping | 4 - chloro - 1,3 - benzenediamine, a chemical, must be shipped in accordance with strict hazardous materials regulations. It should be in well - sealed containers, labeled clearly, and transported by carriers licensed for such chemicals. |
Competitive 4-Chloro-1,3-Benzenediamine prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 4-Chloro-1,3-Benzenediamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of pharmaceutical chemistry, 4-chloro-1,3-phenylenediamine also has important applications. Because of its specific biological activity, it is often a key raw material for the development of new drugs. By modifying and modifying its chemical structure, researchers hope to develop drugs with excellent efficacy and small side effects, which can be used to fight various diseases, such as the development of some antibacterial and anti-inflammatory drugs. It has played an indispensable role.
In addition, in the field of materials science, 4-chloro-1,3-phenylenediamine has also emerged. When preparing high-performance polymer materials, it can participate in the polymerization reaction as a monomer, giving the material unique properties, such as improving the mechanical strength and thermal stability of the material, so as to meet the strict requirements of high-end fields such as aerospace, electronics and electrical appliances for the special properties of the material.
In summary, 4-chloro-1,3-phenylenediamine plays a key role in various fields such as dyes, medicine, and materials, and is of great significance in promoting the development of various industries.
In terms of its melting point, it is within a specific range. This melting point characteristic is a key consideration when related to process operation, purification and separation. Because of the stability of its melting point, the state change of the substance can be precisely controlled in a heated environment, which is beneficial to production practice.
4-Chloro-1,3-phenylenediamine has a certain solubility in solubility, and in some organic solvents, it can exhibit a certain solubility. Such as common alcohol solvents, it can be moderately dissolved in it. This property makes it possible to use a suitable solvent to disperse it uniformly during chemical synthesis and preparation to promote the reaction or achieve a specific preparation form. However, in water, its solubility is relatively limited, which also determines that it needs another strategy when it comes to the application of aqueous systems.
Its density is also a unique physical parameter. Although the value is not widely known, it is indispensable in precise chemical calculation, material ratio and distribution in a specific system. Only by accurately grasping its density can we ensure the accuracy of material measurement in the production process, and then maintain the stability of product quality.
In addition, 4-chloro-1,3-phenylenediamine does not have a special strong odor under normal conditions, which avoids discomfort and interference caused by odor in many use scenarios, enabling its application scenarios to be broadened, whether in industrial production or in some areas with strict odor requirements.
The above physical properties, such as morphology, melting point, solubility, density, and odor, are intertwined to outline the physical characteristics of 4-chloro-1,3-phenylenediamine, providing a solid foundation for its rational application in chemical, pharmaceutical, and other fields.
The nature of an amine group, with the characteristics of a base, can form salts with acids. In aqueous solutions, the nitrogen atom of an amine group can obtain protons and assume a cationic state. This is because the nitrogen atom has an isolated pair of electrons and can combine with protons.
And it is aromatic, because the structure of the benzene ring is stable and has a conjugated system. The aromaticity makes its chemical properties special, such as electrophilic substitution reactions that easily occur on the benzene ring.
The chlorine atom in this molecule is an electron-withdrawing group. It can affect the electron cloud density of the benzene ring, reduce the electron cloud density of the adjacent and para-site of the benzene ring, and the localization effect of the electrophilic substitution reaction is different. Electrophilic reagents tend to react in meta-sites.
Furthermore, 4-chloro-1,3-phenylenediamine may have certain reactivity and can participate in a variety of organic synthesis reactions. If it interacts with acyl halides, acid anhydrides, etc., the amine group can undergo acylation reaction to obtain amide derivatives.
Because of its structure containing chlorine and amine groups, or it has certain toxicity and irritation. When using and contacting, be careful to prevent damage to organisms and the environment. In conclusion, the chemical properties of 4-chloro-1,3-phenylenediamine are formed by the interaction of amino groups, chlorine atoms and benzene rings in its structure, which has a unique position and application in the field of organic chemistry.
The second method can be initiated by the nitrification reaction on the benzene ring. The benzene is first nitrified, and the nitro group is introduced, and then the nitro group is converted into an amino group through a reduction reaction. When introducing chlorine atoms, chlorine atoms can be introduced at specific positions in the benzene ring at a specific stage by using suitable chlorination reagents. In this process, the control of the conditions of each step of the reaction is extremely critical. For example, in the nitrification reaction, the ratio of nitric acid to sulfuric acid, the reaction temperature and other factors will affect the location and yield of nitro groups introduced. The process of reducing nitro groups, the types of reducing agents selected, such as iron filings and hydrochloric acid systems, catalytic hydrogenation and other methods, also have their own advantages and disadvantages and applicable scenarios.
The third method can use some transition metal catalysis reactions. For example, using transition metals such as palladium as catalysts, a coupling reaction between halogenated benzene and amine compounds occurs in the presence of ligands to synthesize the target product. Although this method can accurately achieve the substitution of specific positions on the benzene ring, the catalyst cost is high, and the reaction conditions are relatively harsh, which requires high reaction equipment and operation.
In short, there are various methods for synthesizing 4-chloro-1,3-phenylenediamine, and each method has its own unique characteristics. The most suitable synthesis path needs to be weighed according to actual needs and conditions.
This substance is toxic to a certain extent, and when using it, the first protection should be taken. Be sure to wear suitable protective equipment, such as gloves, goggles and gas masks. Gloves should be made of chemically resistant materials to prevent them from penetrating the skin and causing toxins to invade the body. Goggles can protect the eyes from the damage of the substance splashed out, and gas masks can prevent them from entering the lungs in the form of aerosols, endangering respiration.
Furthermore, the place of use should be well ventilated. When used in a confined space, it is easy to cause its vapor to accumulate and increase the risk of poisoning. Therefore, it is appropriate to operate in a fume hood to circulate air and disperse harmful vapors in time to protect the safety of users.
In addition, 4-chloro-1,3-phenylenediamine is chemically active and easy to react with many substances. When using, do not let it be co-located with strong oxidants, strong acids, strong bases, etc., to prevent violent reactions, fires, explosions and other disasters.
During use, if you accidentally touch the skin or eyes, rinse with plenty of water immediately. If it touches the skin, you need to seek medical attention after rinsing to see if there are any residual toxic effects. If it enters the eye, it should also be rushed to a medical office after rinsing, and it should be handled by a professional doctor to avoid damage to the eyesight.
When taking 4-chloro-1,3-phenylenediamine, the amount must be accurately controlled. Excessive use is not only wasteful, but also causes subsequent treatment difficulties and increases the environmental burden. After use, properly dispose of the residue. Do not dump it at will. When in accordance with relevant regulations, dispose of it at a designated location and according to specific methods to avoid polluting the environment.

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