4-Chloro-1-(4-Chlorophenylsulfonyl)Benzene
Linshang Chemical
HS Code |
575263 |
Chemical Formula | C12H8Cl2O2S |
Molecular Weight | 289.16 |
Appearance | Solid (usually white or off - white powder) |
Physical State At Room Temperature | Solid |
Melting Point | Data needed (varies, usually in a certain range depending on purity) |
Boiling Point | Data needed (difficult to determine directly due to decomposition in some cases) |
Solubility In Water | Low (practically insoluble) |
Solubility In Organic Solvents | Soluble in some organic solvents like dichloromethane, chloroform |
Odor | Odorless or very faint odor |
Density | Data needed (should be measured experimentally for accurate value) |
Stability | Stable under normal conditions, but may react with strong oxidizing agents |
Purity | Can be obtained in various purity levels (e.g., 95%, 98% etc. depending on production method) |
As an accredited 4-Chloro-1-(4-Chlorophenylsulfonyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 100g of 4 - chloro - 1 - (4 - chlorophenylsulfonyl)benzene in a sealed chemical - grade container. |
Storage | Store 4 - chloro - 1 - (4 - chlorophenylsulfonyl)benzene in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent moisture absorption and evaporation. Label the storage container clearly with the chemical name, hazard information, and date of receipt. |
Shipping | 4 - chloro - 1 - (4 - chlorophenylsulfonyl)benzene should be shipped in accordance with hazardous chemical regulations. Use well - sealed containers, label properly, and ensure compliance with transportation safety requirements for such chemicals. |
Competitive 4-Chloro-1-(4-Chlorophenylsulfonyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 4-Chloro-1-(4-Chlorophenylsulfonyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
This compound contains chlorine atoms and benzenesulfonyl groups, and the chlorine atoms have extraordinary activity and can initiate a variety of chemical reactions. For example, nucleophilic substitution reactions, under suitable conditions, chlorine atoms are easily replaced by nucleophiles, such as by hydroxyl (-OH) to form corresponding phenols, and by amino (-NH ²) to obtain nitrogen-containing derivatives. This reaction principle is based on the attack of nucleophilic testers on positively charged chlorine atoms. Due to the strong electron-absorbing ability of chlorine atoms, the carbon atoms connected to them are partially positively charged and vulnerable to attack by nucleophilic reagents.
In addition, benzenesulfonyl also gives the compound special chemical properties. The sulfur atom in benzenesulfonyl is in a high valence state and has strong oxidizing and electrophilic properties. In some reactions, it can participate in the reaction as an electrophilic reagent and react with electron-rich systems. For example, with compounds containing double bonds or aromatic rings, under the action of specific catalysts, electrophilic addition or electrophilic substitution reactions occur.
At the same time, the compound molecule contains multiple benzene rings and has a certain conjugate system, resulting in relatively high stability. The conjugate system can delocalize the electron cloud and reduce the molecular energy. However, the conjugate system also affects the spectral properties of the compound, making it have a specific absorption peak in the ultraviolet-visible spectrum, which can be used for qualitative and quantitative analysis of compounds.
In addition, the physical properties of 4-chloro-1- (4-chlorobenzenesulfonyl) benzene, such as solubility, are affected by its structure. Because it contains multiple hydrophobic benzene rings, its solubility in water is low, but it is easily soluble in organic solvents such as dichloromethane, chloroform, toluene, etc. This solubility property is of great significance in the separation, purification and solvent selection of compounds.
First take an appropriate amount of 4-chlorothiophenol and place it in a clean reactor. Fully replace the air in the kettle with an inert gas such as nitrogen to create an oxygen-free environment. Then, in the state of low temperature stirring, slowly add an appropriate amount of alkali, such as sodium hydroxide solution, to form a salt with 4-chlorothiophenol. This step requires close monitoring of the reaction temperature to prevent large fluctuations in temperature to prevent side reactions from breeding.
Once the salt is formed, heat the reaction system to a moderate temperature, and then add the solution containing 4-chlorobenzenesulfonyl chloride dropwise. This process also needs to be maintained with stirring to facilitate the material to fully contact the reaction. The drop acceleration of 4-chlorobenzenesulfonyl chloride should be slow to prevent the reaction from being too violent.
After the dropwise addition is completed, continue to stir the reaction for a period of time to make the reaction fully proceed. During this period, the reaction process can be monitored by means of thin-layer chromatography. When the raw material points are almost gone, the reaction is almost complete.
After the reaction is completed, pour the reaction liquid into an appropriate amount of ice water to quench the reaction and precipitate solid products at the same time. Filter through a Brinell funnel, collect the solid, and wash it with an appropriate amount of cold water to remove impurities.
The obtained solid crude product can be purified by recrystallization. Select a suitable solvent, such as ethanol-water mixed solvent, heat the crude product to dissolve, and filter it while hot to remove insoluble impurities. The filtrate is allowed to stand and cool, until the crystallization is complete, filter again, collect the crystals, and dry it at low temperature in an oven to obtain pure 4-chloro-1 - (4-chlorobenzenesulfonyl) benzene. The entire preparation process requires strict compliance with operating procedures, attention to safety, and proper disposal of waste to ensure smooth experiment and environmental safety.
In the field of pharmaceutical research and development, it may be the key intermediate for the creation of new drugs. Due to its unique chemical structure, various active groups can be introduced by organic synthesis, modified and transformed to obtain compounds with specific pharmacological activities. For example, for some biological targets involved in specific diseases, by ingeniously designing synthetic routes, using this compound as a starting material, and gradually building drug molecules that can act precisely on the target, it is expected to open up new paths for the treatment of diseases.
In the field of materials science, it can also be. It can be integrated into the structure of a polymer through specific reactions. In this way, it may endow materials with special optical and electrical properties, or enhance their mechanical properties and stability. For example, in the preparation of high-performance engineering plastics, the introduction of this compound may improve the chemical corrosion resistance and heat resistance of plastics, broadening its application range in high-temperature, reinforced media environments.
Furthermore, in the field of fine chemicals, it is an important raw material for the synthesis of fine chemicals, which can be used to prepare special dyes, pigments and high-performance additives. In dye synthesis, with its structural characteristics, new dyes with bright colors and high light fastness can be developed to meet the needs of high-quality dyes in textile, printing and other industries.
In summary, 4-chloro-1 - (4-chlorobenzenesulfonyl) benzene has shown considerable application potential in many fields such as medicine, materials, and fine chemicals, and is indeed a valuable compound in organic synthetic chemistry.
Looking at its prospects in the chemical industry, in the fine chemical industry, it may be used as a key intermediate for the synthesis of special functional materials. With the advance of science and technology, the demand for high-end materials is increasing, such as high-performance insulating materials for electronic devices, optical materials, etc. If it can participate in the synthesis of such materials, and the synthesis process is optimized with controllable cost and considerable yield, it will be able to occupy a place in the chemical market. Nowadays, the scale of the fine chemical market is expanding rapidly, and the demand for characteristic intermediates is also rising. If this compound can meet the market demand for specific structures and properties, it is expected to emerge in many chemical raw materials.
In the field of medicine, it may have the value of drug research and development. Modern medicinal chemistry is often based on specific organic structures, and new drugs are developed by modification. This compound contains chlorine atoms and benzenesulfonyl structures. Chlorine atoms can regulate the lipophilic and electrical properties of molecules. Benzenesulfonyl groups also have important effects on molecular activity and stability. Similar structures are seen in many drugs to play key pharmacological roles. Over time, researchers may be able to use advanced drug design methods, such as computer-aided drug design, as the starting structure to design and synthesize innovative drugs targeting specific disease targets. Once successful, with the growth of the global population, the aging of the population and the increasing emphasis on health, the pharmaceutical market has a huge demand for innovative drugs, and its market prospects are limitless.
However, its market development also faces challenges. In terms of synthetic processes, if the process is complicated, expensive, or produces a lot of pollutants, it will limit large-scale production and marketing activities. And the market competition is fierce. If similar structural compounds or other alternatives are available, they need to highlight their unique advantages. But overall, with technological progress and market expansion, 4-chloro-1- (4-chlorobenzenesulfonyl) benzene still has a broad market development space.
Let's talk about NabASF first. This is a global chemical giant. It has deep skills in the research and development and production of fine chemicals. With its advanced technology and strict quality control system, the 4 - chloro - 1 - (4 - chlorobenzenesulfonyl) benzene produced is of high quality and has a good reputation in the international market. It is exported to various places and is favored by many downstream industries.
Furthermore, Dow Chemical is also a leader in the industry. Its scientific research force is strong and it is constantly innovating. In the production of 4-chloro-1 - (4-chlorobenzenesulfonyl) benzene, with its unique technical path, it not only guarantees the stability of product quality, but also has excellent performance in production efficiency, which can meet large-scale market demand.
Some domestic manufacturers have also emerged in the field of product production. For example, a large chemical enterprise, relying on the advantages of abundant domestic resources and the unremitting pursuit of technology, produces 4-chloro-1 - (4-chlorobenzenesulfonyl) benzene, which is cost-effective and occupies a certain share in the domestic market. And gradually expand the overseas market, showing a strong development momentum.
These several manufacturers, either with technology or resources, have shown their talents in the production field of 4-chloro-1 - (4-chlorobenzenesulfonyl) benzene, and jointly promote the market supply and industry development of this product.

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