Linshang Chemical
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4-Chloro-1-(Chloromethyl)-2-Fluorobenzene
Linshang Chemical
|
HS Code |
965412 |
| Chemical Formula | C7H5Cl2F |
| Molecular Weight | 181.019 |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | Around 200 - 210 °C |
| Density | Approx. 1.35 - 1.45 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Vapor Pressure | Low at room temperature |
| Flash Point | Around 80 - 90 °C |
As an accredited 4-Chloro-1-(Chloromethyl)-2-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 4 - chloro - 1 - (chloromethyl) - 2 - fluorobenzene in sealed chemical - grade bottle. |
| Storage | 4 - chloro - 1 - (chloromethyl)-2 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from sources of heat, sparks, and open flames due to its flammability risk. Keep it in a tightly sealed container to prevent vapor release. Store separately from oxidizing agents and incompatible substances to avoid potential reactions. Label containers clearly for easy identification and safety. |
| Shipping | 4 - chloro - 1 - (chloromethyl)-2 - fluorobenzene, a hazardous chemical, is shipped in specialized, leak - proof containers. Shipment follows strict regulations, ensuring proper labeling, handling, and transportation to prevent any environmental or safety risks. |
Competitive 4-Chloro-1-(Chloromethyl)-2-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Chloro-1-(Chloromethyl)-2-Fluorobenzene in China?
As a trusted 4-Chloro-1-(Chloromethyl)-2-Fluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Chloro-1-(Chloromethyl)-2-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4-chloro-1- (chloromethyl) -2-fluorobenzene?
4-Chloro-1- (chloromethyl) -2-fluorobenzene is also an organic compound. Its main use is more common in the field of organic synthesis.
In the field of pharmaceutical chemistry, this compound is often an important intermediate. Due to the properties of chlorine, chloromethyl and fluorine atoms in its structure, it can participate in various chemical reactions to construct complex drug molecular structures. Through halogenation reactions, nucleophilic substitution reactions, etc., chemists can introduce specific functional groups to modify drug activity and pharmacological properties.
It also has its uses in materials science. It can participate in the polymerization reaction as a monomer, giving the material unique physical and chemical properties, such as improving the heat resistance and chemical corrosion resistance of the material. Because of its fluorine atom, fluorine has high electronegativity and can improve the stability and hydrophobicity of the material, which is very important in the preparation of special materials.
Furthermore, in the field of pesticide synthesis, 4-chloro-1- (chloromethyl) -2-fluorobenzene also plays an important role. It can be converted into compounds with insecticidal, bactericidal or herbicidal activities through a series of reactions, and its special structure interacts with the biological activity check point to achieve effective control of harmful organisms.
In summary, the unique chemical structure of 4-chloro-1- (chloromethyl) -2-fluorobenzene has important uses in many fields such as organic synthesis, medicinal chemistry, materials science and pesticide synthesis, and is an indispensable basic compound for the development of related industries.
In the field of pharmaceutical chemistry, this compound is often an important intermediate. Due to the properties of chlorine, chloromethyl and fluorine atoms in its structure, it can participate in various chemical reactions to construct complex drug molecular structures. Through halogenation reactions, nucleophilic substitution reactions, etc., chemists can introduce specific functional groups to modify drug activity and pharmacological properties.
It also has its uses in materials science. It can participate in the polymerization reaction as a monomer, giving the material unique physical and chemical properties, such as improving the heat resistance and chemical corrosion resistance of the material. Because of its fluorine atom, fluorine has high electronegativity and can improve the stability and hydrophobicity of the material, which is very important in the preparation of special materials.
Furthermore, in the field of pesticide synthesis, 4-chloro-1- (chloromethyl) -2-fluorobenzene also plays an important role. It can be converted into compounds with insecticidal, bactericidal or herbicidal activities through a series of reactions, and its special structure interacts with the biological activity check point to achieve effective control of harmful organisms.
In summary, the unique chemical structure of 4-chloro-1- (chloromethyl) -2-fluorobenzene has important uses in many fields such as organic synthesis, medicinal chemistry, materials science and pesticide synthesis, and is an indispensable basic compound for the development of related industries.
What are the physical properties of 4-chloro-1- (chloromethyl) -2-fluorobenzene
4-Chloro-1- (chloromethyl) -2-fluorobenzene is a kind of organic compound. Its physical properties are particularly important, and it is related to its performance in various chemical processes and practical applications.
First of all, its appearance, under normal circumstances, is mostly colorless to light yellow liquid, clear and with a specific luster, giving people a sense of clarity. This appearance characteristic is of great significance when identifying and preliminarily determining its state.
As for its boiling point, it is within a certain temperature range. The boiling point is the critical temperature at which a substance changes from liquid to gas. The boiling point of 4-chloro-1- (chloromethyl) -2-fluorobenzene makes it possible to change the phase state under the corresponding temperature conditions, which is a key parameter in chemical operations such as distillation and separation.
Melting point is also one of its important physical properties. Melting point refers to the temperature at which a substance changes from a solid to a liquid state. The specific melting point of 4-chloro-1- (chloromethyl) -2-fluorobenzene determines its existence and form under different temperature environments. It is of great significance for the setting of storage and transportation conditions.
Furthermore, its density is also fixed. The density is also the mass of the substance per unit volume. The density of 4-chloro-1- (chloromethyl) -2-fluorobenzene affects its distribution when mixed with other substances, and cannot be ignored in solution preparation and reaction system construction.
In terms of solubility, 4-chloro-1- (chloromethyl) -2-fluorobenzene often exhibits good solubility in organic solvents and can be miscible with many organic solvents. However, in water, its solubility is poor. This solubility characteristic is an important basis for selecting suitable solvents in chemical operations such as extraction and washing.
In addition, its volatility also belongs to the category of physical properties. 4-Chloro-1- (chloromethyl) -2-fluorobenzene is volatile to a certain extent. In an open environment, it will gradually evaporate from liquid to gaseous state. This property needs to be considered during storage and should be properly sealed to prevent its volatilization and escape, causing loss or causing safety problems.
In summary, the physical properties of 4-chloro-1- (chloromethyl) -2-fluorobenzene, such as appearance, boiling point, melting point, density, solubility and volatility, are interrelated and play an important role. They are all indispensable factors in many fields such as chemical research and industrial production.
First of all, its appearance, under normal circumstances, is mostly colorless to light yellow liquid, clear and with a specific luster, giving people a sense of clarity. This appearance characteristic is of great significance when identifying and preliminarily determining its state.
As for its boiling point, it is within a certain temperature range. The boiling point is the critical temperature at which a substance changes from liquid to gas. The boiling point of 4-chloro-1- (chloromethyl) -2-fluorobenzene makes it possible to change the phase state under the corresponding temperature conditions, which is a key parameter in chemical operations such as distillation and separation.
Melting point is also one of its important physical properties. Melting point refers to the temperature at which a substance changes from a solid to a liquid state. The specific melting point of 4-chloro-1- (chloromethyl) -2-fluorobenzene determines its existence and form under different temperature environments. It is of great significance for the setting of storage and transportation conditions.
Furthermore, its density is also fixed. The density is also the mass of the substance per unit volume. The density of 4-chloro-1- (chloromethyl) -2-fluorobenzene affects its distribution when mixed with other substances, and cannot be ignored in solution preparation and reaction system construction.
In terms of solubility, 4-chloro-1- (chloromethyl) -2-fluorobenzene often exhibits good solubility in organic solvents and can be miscible with many organic solvents. However, in water, its solubility is poor. This solubility characteristic is an important basis for selecting suitable solvents in chemical operations such as extraction and washing.
In addition, its volatility also belongs to the category of physical properties. 4-Chloro-1- (chloromethyl) -2-fluorobenzene is volatile to a certain extent. In an open environment, it will gradually evaporate from liquid to gaseous state. This property needs to be considered during storage and should be properly sealed to prevent its volatilization and escape, causing loss or causing safety problems.
In summary, the physical properties of 4-chloro-1- (chloromethyl) -2-fluorobenzene, such as appearance, boiling point, melting point, density, solubility and volatility, are interrelated and play an important role. They are all indispensable factors in many fields such as chemical research and industrial production.
What are the synthesis methods of 4-chloro-1- (chloromethyl) -2-fluorobenzene?
4-Chloro-1- (chloromethyl) -2-fluorobenzene is also an organic compound. The method of its synthesis can be roughly numbered.
First, it can be started from the corresponding phenols. First, phenols containing chlorine and fluorine are prepared by using phenols as raw materials. After halogenation, chlorine atoms and fluorine atoms are introduced into the benzene ring. Then, the phenols are reacted with halogenated hydrocarbons, and chloromethyl is introduced into the phenolic hydroxyl ortho-position. The choice of halogenated hydrocarbons must meet the conditions and requirements of the reaction. After many steps, the target product can be obtained.
Second, halogenated aromatics are used as the starting materials. Select the appropriate halogenated benzene, the type and position of the halogen atoms on it are related to the process of the reaction and the structure of the product. First, a specific substitution reaction is carried out on the halogenated benzene to introduce fluorine atoms, and then chloromethylation is carried out to connect chloromethyl to the benzene ring. This chloromethylation reaction often requires a suitable catalyst and reaction environment to make the reaction proceed smoothly and achieve the expected yield.
Third, or by the electrophilic substitution reaction of the benzene ring. Using benzene as the starting material, the halogenation reaction first introduces chlorine atoms and fluorine atoms in turn to obtain a specific halogenated benzene. Subsequently, the chloromethylation reaction is carried out by using electrophilic reagents. During this process, the temperature of the reaction, the ratio of reagents and other conditions need to be carefully adjusted to prevent side reactions and ensure the purity and yield of the product.
The process of synthesis has its own advantages and disadvantages. The selection of starting materials, the control of reaction conditions, and the avoidance of side reactions are all the keys to the synthesis. To obtain 4-chloro-1 - (chloromethyl) -2-fluorobenzene with high purity and high yield, it is necessary to carefully consider each reaction step and operate with caution.
First, it can be started from the corresponding phenols. First, phenols containing chlorine and fluorine are prepared by using phenols as raw materials. After halogenation, chlorine atoms and fluorine atoms are introduced into the benzene ring. Then, the phenols are reacted with halogenated hydrocarbons, and chloromethyl is introduced into the phenolic hydroxyl ortho-position. The choice of halogenated hydrocarbons must meet the conditions and requirements of the reaction. After many steps, the target product can be obtained.
Second, halogenated aromatics are used as the starting materials. Select the appropriate halogenated benzene, the type and position of the halogen atoms on it are related to the process of the reaction and the structure of the product. First, a specific substitution reaction is carried out on the halogenated benzene to introduce fluorine atoms, and then chloromethylation is carried out to connect chloromethyl to the benzene ring. This chloromethylation reaction often requires a suitable catalyst and reaction environment to make the reaction proceed smoothly and achieve the expected yield.
Third, or by the electrophilic substitution reaction of the benzene ring. Using benzene as the starting material, the halogenation reaction first introduces chlorine atoms and fluorine atoms in turn to obtain a specific halogenated benzene. Subsequently, the chloromethylation reaction is carried out by using electrophilic reagents. During this process, the temperature of the reaction, the ratio of reagents and other conditions need to be carefully adjusted to prevent side reactions and ensure the purity and yield of the product.
The process of synthesis has its own advantages and disadvantages. The selection of starting materials, the control of reaction conditions, and the avoidance of side reactions are all the keys to the synthesis. To obtain 4-chloro-1 - (chloromethyl) -2-fluorobenzene with high purity and high yield, it is necessary to carefully consider each reaction step and operate with caution.
What to pay attention to when storing and transporting 4-chloro-1- (chloromethyl) -2-fluorobenzene
4-Chloro-1- (chloromethyl) -2-fluorobenzene is also an organic compound. When storing and transporting, pay attention to many matters.
First words storage. This substance should be placed in a cool, dry and well-ventilated place. Because of its certain chemical activity, high temperature and humid environment, it is easy to cause it to deteriorate. If it is exposed to high temperature, or causes molecular structure changes, it will cause chemical reactions and damage its quality. Therefore, choose a cool and dry place to keep its chemical properties stable. Furthermore, it must be stored separately from oxidants, alkalis and other substances. Cover 4 - chloro - 1 - (chloromethyl) - 2 - fluorobenzene meets the oxidant, or causes a violent oxidation reaction, there is a risk of explosion; contact with alkalis may also trigger a chemical reaction and change its chemical composition. And the storage place should be equipped with suitable materials to contain leaks in case of leakage, which can be dealt with in time to avoid greater harm.
As for transportation, it should not be taken lightly. Make sure that the packaging is complete and sealed before transportation. If the packaging is damaged and the substance leaks, it will not only pollute the environment, but also pose a threat to the safety of transporters. During transportation, the speed of the vehicle should be stable to avoid bumps and vibrations. Violent vibration or damage to the packaging, causing leakage. Transport vehicles should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. In case of emergency situations such as leakage on the way, measures can be taken quickly to deal with it. At the same time, transport personnel must be professionally trained and familiar with the nature of the substance and emergency treatment methods before they can act. In this way, 4-chloro-1 - (chloromethyl) - 2 - fluorobenzene can be guaranteed to be safe during storage and transportation to avoid accidents.
First words storage. This substance should be placed in a cool, dry and well-ventilated place. Because of its certain chemical activity, high temperature and humid environment, it is easy to cause it to deteriorate. If it is exposed to high temperature, or causes molecular structure changes, it will cause chemical reactions and damage its quality. Therefore, choose a cool and dry place to keep its chemical properties stable. Furthermore, it must be stored separately from oxidants, alkalis and other substances. Cover 4 - chloro - 1 - (chloromethyl) - 2 - fluorobenzene meets the oxidant, or causes a violent oxidation reaction, there is a risk of explosion; contact with alkalis may also trigger a chemical reaction and change its chemical composition. And the storage place should be equipped with suitable materials to contain leaks in case of leakage, which can be dealt with in time to avoid greater harm.
As for transportation, it should not be taken lightly. Make sure that the packaging is complete and sealed before transportation. If the packaging is damaged and the substance leaks, it will not only pollute the environment, but also pose a threat to the safety of transporters. During transportation, the speed of the vehicle should be stable to avoid bumps and vibrations. Violent vibration or damage to the packaging, causing leakage. Transport vehicles should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. In case of emergency situations such as leakage on the way, measures can be taken quickly to deal with it. At the same time, transport personnel must be professionally trained and familiar with the nature of the substance and emergency treatment methods before they can act. In this way, 4-chloro-1 - (chloromethyl) - 2 - fluorobenzene can be guaranteed to be safe during storage and transportation to avoid accidents.
What are the environmental effects of 4-chloro-1- (chloromethyl) -2-fluorobenzene?
4-Chloro-1- (chloromethyl) -2-fluorobenzene is one of the organic compounds. Its impact on the environment needs to be carefully reviewed.
If this substance is released in the atmosphere, it is volatile to a certain extent, or it can migrate and diffuse in the air. However, its chemical stability may make it more difficult to degrade quickly through atmospheric photochemical reactions. It is diffuse in the air, or can cause changes in air quality. If inhaled, it may damage the respiratory tract and lungs, causing cough, asthma and other diseases.
If it flows in water, it can be adsorbed on suspended particles due to its hydrophobicity or insolubility in water, and migrate with the water flow. This compound may be toxic to aquatic organisms, damage their physiological functions, cause growth, reproduction, and even death. And may be enriched through the food chain, endangering high-rise organisms.
As for the soil, it may be retained due to adsorption, affecting the activity and community structure of soil microorganisms, disturbing the balance of soil ecosystems, and then unfavorable to plant growth, or causing plants to absorb this substance, causing agricultural products to be contaminated and endangering food safety.
In summary, 4-chloro-1- (chloromethyl) -2-fluorobenzene can be affected in various media in the environment, which is related to ecological balance and human health. It is necessary to treat it with caution and strictly control its discharge and use to reduce its harm to the environment.
If this substance is released in the atmosphere, it is volatile to a certain extent, or it can migrate and diffuse in the air. However, its chemical stability may make it more difficult to degrade quickly through atmospheric photochemical reactions. It is diffuse in the air, or can cause changes in air quality. If inhaled, it may damage the respiratory tract and lungs, causing cough, asthma and other diseases.
If it flows in water, it can be adsorbed on suspended particles due to its hydrophobicity or insolubility in water, and migrate with the water flow. This compound may be toxic to aquatic organisms, damage their physiological functions, cause growth, reproduction, and even death. And may be enriched through the food chain, endangering high-rise organisms.
As for the soil, it may be retained due to adsorption, affecting the activity and community structure of soil microorganisms, disturbing the balance of soil ecosystems, and then unfavorable to plant growth, or causing plants to absorb this substance, causing agricultural products to be contaminated and endangering food safety.
In summary, 4-chloro-1- (chloromethyl) -2-fluorobenzene can be affected in various media in the environment, which is related to ecological balance and human health. It is necessary to treat it with caution and strictly control its discharge and use to reduce its harm to the environment.
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