Linshang Chemical
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4-Chloro-1-Iodo-2-Methylbenzene
Linshang Chemical
|
HS Code |
868258 |
| Chemical Formula | C7H6ClI |
| Molar Mass | 254.48 g/mol |
| Appearance | Liquid (usually) |
| Odor | Characteristic aromatic odor |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
As an accredited 4-Chloro-1-Iodo-2-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - chloro - 1 - iodo - 2 - methylbenzene packaged in a sealed glass bottle. |
| Storage | 4 - chloro - 1 - iodo - 2 - methylbenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent vapor leakage. Since it is likely a flammable and potentially hazardous chemical, store it separately from oxidizing agents and reactive substances to avoid dangerous reactions. |
| Shipping | 4 - chloro - 1 - iodo - 2 - methylbenzene should be shipped in tightly sealed, corrosion - resistant containers. It must comply with hazardous chemical shipping regulations, with proper labeling indicating its nature for safe transportation. |
Competitive 4-Chloro-1-Iodo-2-Methylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
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What is the Chinese name of 4-chloro-1-iodo-2-methylbenzene?
4-Chloro-1-iodine-2-methylbenzene, this is the name of an organic compound. According to the chemical nomenclature, the substituent is first, followed by the main benzene ring. "4-chloro" means that the chlorine atom is at the 4th position of the benzene ring; "1-iodine" means that the iodine atom is at the 1st position of the benzene ring; "2-methyl" means that the methyl is at the 2nd position of the benzene ring.
The benzene ring, an important structure in organic chemistry, has unique stability. Its six carbon atoms form a ring and are connected by a conjugated double bond. In this compound, the benzene ring is the main structure, and chlorine, iodine, and methyl are the substituents, which are connected to the specific position of the benzene ring.
As halogen elements, chlorine and iodine have certain electronegativity, which often affects the polarity and activity of molecules in chemical reactions. Methyl is a hydrocarbon group, which can change the electron cloud distribution of the benzene ring and affect the physical and chemical properties of the compound.
This compound may have important uses in the field of organic synthesis. It can be used as an intermediate to participate in various organic reactions and prepare more complex organic compounds. It may have potential value in the fields of medicinal chemistry and materials science.
The benzene ring, an important structure in organic chemistry, has unique stability. Its six carbon atoms form a ring and are connected by a conjugated double bond. In this compound, the benzene ring is the main structure, and chlorine, iodine, and methyl are the substituents, which are connected to the specific position of the benzene ring.
As halogen elements, chlorine and iodine have certain electronegativity, which often affects the polarity and activity of molecules in chemical reactions. Methyl is a hydrocarbon group, which can change the electron cloud distribution of the benzene ring and affect the physical and chemical properties of the compound.
This compound may have important uses in the field of organic synthesis. It can be used as an intermediate to participate in various organic reactions and prepare more complex organic compounds. It may have potential value in the fields of medicinal chemistry and materials science.
What are the physical properties of 4-chloro-1-iodo-2-methylbenzene?
4-Chloro-1-iodine-2-methylbenzene is a kind of organic compound. Its physical properties are quite important and are related to many chemical applications.
Looking at its appearance, under normal temperature and pressure, this substance is often colorless to light yellow liquid, with a relatively clear texture and a certain fluidity. This appearance property is crucial for the identification and preliminary judgment of this substance.
When it comes to boiling point, the boiling point of 4-chloro-1-iodine-2-methylbenzene is quite high, about a certain temperature range. This property requires it to reach a certain high temperature during heating before it can be converted into a gaseous state. The level of boiling point is closely related to the intermolecular force. The intermolecular force of this compound causes its boiling point to be in a specific range, which is of great significance in the process of separation and purification. It can be separated from the mixture by distillation and other means according to the difference in boiling point.
In terms of melting point, it also has a specific value. Under a specific low temperature environment, 4-chloro-1-iodine-2-methylbenzene will change from liquid to solid. This melting point characteristic needs to be taken into account during storage and transportation. If the ambient temperature is close to or below the melting point, the substance may be in a solid state, which affects its access and operation.
The density of 4-chloro-1-iodine-2-methylbenzene is greater than that of water. When mixed with water, it will sink to the bottom of the water. This density characteristic can be used in liquid-liquid separation operations to achieve separation from water and other liquids of different densities according to density differences.
Solubility is also an important physical property. It is insoluble in water, but soluble in some organic solvents, such as common ethanol, ether, etc. This solubility characteristic has a significant impact in chemical reactions. Choosing a suitable organic solvent as the reaction medium can promote the reaction. Due to the different solubility of different solvents to the reactants, the reaction rate and product distribution will be changed.
In addition, 4-chloro-1-iodine-2-methylbenzene is volatile and will gradually evaporate in the air. Although the volatilization rate is not extremely fast, long-term exposure will still cause material loss. When storing, it is necessary to pay attention to sealing to prevent loss and environmental pollution caused by volatilization. And because of its volatility, it is also necessary to pay attention to ventilation in the place of use to ensure environmental safety.
Looking at its appearance, under normal temperature and pressure, this substance is often colorless to light yellow liquid, with a relatively clear texture and a certain fluidity. This appearance property is crucial for the identification and preliminary judgment of this substance.
When it comes to boiling point, the boiling point of 4-chloro-1-iodine-2-methylbenzene is quite high, about a certain temperature range. This property requires it to reach a certain high temperature during heating before it can be converted into a gaseous state. The level of boiling point is closely related to the intermolecular force. The intermolecular force of this compound causes its boiling point to be in a specific range, which is of great significance in the process of separation and purification. It can be separated from the mixture by distillation and other means according to the difference in boiling point.
In terms of melting point, it also has a specific value. Under a specific low temperature environment, 4-chloro-1-iodine-2-methylbenzene will change from liquid to solid. This melting point characteristic needs to be taken into account during storage and transportation. If the ambient temperature is close to or below the melting point, the substance may be in a solid state, which affects its access and operation.
The density of 4-chloro-1-iodine-2-methylbenzene is greater than that of water. When mixed with water, it will sink to the bottom of the water. This density characteristic can be used in liquid-liquid separation operations to achieve separation from water and other liquids of different densities according to density differences.
Solubility is also an important physical property. It is insoluble in water, but soluble in some organic solvents, such as common ethanol, ether, etc. This solubility characteristic has a significant impact in chemical reactions. Choosing a suitable organic solvent as the reaction medium can promote the reaction. Due to the different solubility of different solvents to the reactants, the reaction rate and product distribution will be changed.
In addition, 4-chloro-1-iodine-2-methylbenzene is volatile and will gradually evaporate in the air. Although the volatilization rate is not extremely fast, long-term exposure will still cause material loss. When storing, it is necessary to pay attention to sealing to prevent loss and environmental pollution caused by volatilization. And because of its volatility, it is also necessary to pay attention to ventilation in the place of use to ensure environmental safety.
What are the chemical properties of 4-chloro-1-iodo-2-methylbenzene?
4-Chloro-1-iodine-2-methylbenzene is an organic compound with specific chemical properties.
Its chemical activity originates from the substituent group on the benzene ring. Chlorine and iodine atoms are electron-absorbing groups, and methyl groups are electron-donating groups. This structural property makes the compound exhibit a unique reaction tendency.
In the electrophilic substitution reaction, the electron-donating effect of methyl makes the electron cloud density of the ortho and para-sites of the benzene ring increase, and the electrophilic reagents are more likely to attack the ortho and para-sites. However, the electron-absorbing effect of chlorine and iodine disperses the electron cloud of the benzene ring to a certain extent and reduces the activity of the benzene
In the nature of halogenated hydrocarbons, chlorine and iodine atoms can participate in the substitution reaction. Under the action of nucleophiles, chlorine or iodine atoms can be replaced by other groups. For example, when reacted with sodium alcohol, corresponding ether compounds can be formed; when reacted with ammonia or amine, nitrogen-containing derivatives can be obtained.
In addition, because the C-I bond energy of the iodine atom is relatively low, it is easier to break, which makes the site highly reactive under specific conditions, or initiates other types of reactions such as elimination reactions. At the same time, the conjugation system of the benzene ring endows the compound with certain stability, so that the reaction conditions and product distribution are affected by the conjugation effect. The chemical properties of this compound are of great significance in the field of organic synthesis, and can be used as a key intermediate to construct complex organic molecular structures through various reaction pathways.
Its chemical activity originates from the substituent group on the benzene ring. Chlorine and iodine atoms are electron-absorbing groups, and methyl groups are electron-donating groups. This structural property makes the compound exhibit a unique reaction tendency.
In the electrophilic substitution reaction, the electron-donating effect of methyl makes the electron cloud density of the ortho and para-sites of the benzene ring increase, and the electrophilic reagents are more likely to attack the ortho and para-sites. However, the electron-absorbing effect of chlorine and iodine disperses the electron cloud of the benzene ring to a certain extent and reduces the activity of the benzene
In the nature of halogenated hydrocarbons, chlorine and iodine atoms can participate in the substitution reaction. Under the action of nucleophiles, chlorine or iodine atoms can be replaced by other groups. For example, when reacted with sodium alcohol, corresponding ether compounds can be formed; when reacted with ammonia or amine, nitrogen-containing derivatives can be obtained.
In addition, because the C-I bond energy of the iodine atom is relatively low, it is easier to break, which makes the site highly reactive under specific conditions, or initiates other types of reactions such as elimination reactions. At the same time, the conjugation system of the benzene ring endows the compound with certain stability, so that the reaction conditions and product distribution are affected by the conjugation effect. The chemical properties of this compound are of great significance in the field of organic synthesis, and can be used as a key intermediate to construct complex organic molecular structures through various reaction pathways.
What are the main uses of 4-chloro-1-iodo-2-methylbenzene?
4-Chloro-1-iodine-2-methylbenzene is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of organic synthesis.
In organic synthesis, complex organic molecular structures can be constructed through various chemical reactions with its specific substituents. For example, chlorine atoms and iodine atoms have different activities, and can be substituted with many nucleophiles under different reaction conditions, introducing the required functional groups, and then synthesizing organic compounds with specific properties and structures.
In the field of materials science, 4-chloro-1-iodine-2-methylbenzene can be used as a starting material to prepare polymer materials with special properties. After proper polymerization, its structural units are integrated into the polymer chain, imparting materials such as good solubility, thermal stability or optical properties.
In the field of medicinal chemistry, it is also of great value. Due to its unique chemical structure, it can be used as a basic module for the design and synthesis of drug molecules. Through structural modification and modification, compounds with biological activity can be synthesized for drug research and development, or it is expected to become an effective drug for the treatment of specific diseases.
In addition, in the preparation of fine chemical products, such as dyes and fragrances, 4-chloro-1-iodine-2-methylbenzene can be used as an important raw material or intermediate to impart specific color, odor and other characteristics to the product. In short, this compound plays an indispensable role in many chemical-related fields and is of great significance to the development of chemical synthesis technology and related industries.
In organic synthesis, complex organic molecular structures can be constructed through various chemical reactions with its specific substituents. For example, chlorine atoms and iodine atoms have different activities, and can be substituted with many nucleophiles under different reaction conditions, introducing the required functional groups, and then synthesizing organic compounds with specific properties and structures.
In the field of materials science, 4-chloro-1-iodine-2-methylbenzene can be used as a starting material to prepare polymer materials with special properties. After proper polymerization, its structural units are integrated into the polymer chain, imparting materials such as good solubility, thermal stability or optical properties.
In the field of medicinal chemistry, it is also of great value. Due to its unique chemical structure, it can be used as a basic module for the design and synthesis of drug molecules. Through structural modification and modification, compounds with biological activity can be synthesized for drug research and development, or it is expected to become an effective drug for the treatment of specific diseases.
In addition, in the preparation of fine chemical products, such as dyes and fragrances, 4-chloro-1-iodine-2-methylbenzene can be used as an important raw material or intermediate to impart specific color, odor and other characteristics to the product. In short, this compound plays an indispensable role in many chemical-related fields and is of great significance to the development of chemical synthesis technology and related industries.
What are 4-chloro-1-iodo-2-methylbenzene synthesis methods?
The common methods for synthesizing 4-chloro-1-iodine-2-methylbenzene are as follows.
First, o-methyl chlorobenzene is used as the starting material. Under specific conditions, o-methyl chlorobenzene undergoes an electrophilic substitution reaction with iodine. This reaction requires careful selection of suitable catalysts and reaction environments. For example, under appropriate Lewis acid catalysis, iodine can selectively replace hydrogen atoms at specific positions on the benzene ring to obtain 4-chloro-1-iodine-2-methylbenzene. During this period, many factors such as the type and dosage of catalysts, reaction temperature and time have significant effects on the yield and selectivity of the reaction.
Second, it can be started from o-methyl iodobenzene. Let o-methyl iodobenzene react with chlorine in a suitable reaction system. Usually chlorine gas or chlorine-containing compounds can be selected as the chlorine source. Under suitable reaction conditions, such as specific solvents, temperatures and catalysts, chlorine atoms replace hydrogen on the benzene ring to achieve the synthesis of 4-chloro-1-iodine-2-methyl benzene. In this process, the polarity of the solvent and the temperature of the reaction will affect the process of the reaction and the purity of the product.
Furthermore, 2-methylbenzoic acid can also be used as the starting material. First, 2-methylbenzoic acid is converted into the corresponding acid chloride, and then chlorine and iodine atoms are introduced through a series of reactions, such as the Fu-Ke reaction. This path step is relatively complicated, but if the reaction conditions of each step are properly controlled, the target product can also be obtained. Attention should be paid to the optimization of the reaction conditions at each step in the reaction process to improve the yield and quality of the product.
Synthesis of 4-chloro-1-iodine-2-methylbenzene has its own advantages and disadvantages. In practical application, the appropriate synthesis path should be carefully selected according to the specific situation, such as the availability of raw materials, cost, and requirements for product purity.
First, o-methyl chlorobenzene is used as the starting material. Under specific conditions, o-methyl chlorobenzene undergoes an electrophilic substitution reaction with iodine. This reaction requires careful selection of suitable catalysts and reaction environments. For example, under appropriate Lewis acid catalysis, iodine can selectively replace hydrogen atoms at specific positions on the benzene ring to obtain 4-chloro-1-iodine-2-methylbenzene. During this period, many factors such as the type and dosage of catalysts, reaction temperature and time have significant effects on the yield and selectivity of the reaction.
Second, it can be started from o-methyl iodobenzene. Let o-methyl iodobenzene react with chlorine in a suitable reaction system. Usually chlorine gas or chlorine-containing compounds can be selected as the chlorine source. Under suitable reaction conditions, such as specific solvents, temperatures and catalysts, chlorine atoms replace hydrogen on the benzene ring to achieve the synthesis of 4-chloro-1-iodine-2-methyl benzene. In this process, the polarity of the solvent and the temperature of the reaction will affect the process of the reaction and the purity of the product.
Furthermore, 2-methylbenzoic acid can also be used as the starting material. First, 2-methylbenzoic acid is converted into the corresponding acid chloride, and then chlorine and iodine atoms are introduced through a series of reactions, such as the Fu-Ke reaction. This path step is relatively complicated, but if the reaction conditions of each step are properly controlled, the target product can also be obtained. Attention should be paid to the optimization of the reaction conditions at each step in the reaction process to improve the yield and quality of the product.
Synthesis of 4-chloro-1-iodine-2-methylbenzene has its own advantages and disadvantages. In practical application, the appropriate synthesis path should be carefully selected according to the specific situation, such as the availability of raw materials, cost, and requirements for product purity.
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