Linshang Chemical
PRODUCTS
4-Chloro-2,3-Difluoronitrobenzene
Linshang Chemical
|
HS Code |
310298 |
| Chemical Formula | C6H2ClF2NO2 |
| Appearance | Yellow to light brown solid |
| Boiling Point | Approx. 230 - 232 °C |
| Melting Point | 40 - 44 °C |
| Density | 1.56 g/cm³ (approx.) |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone |
| Flash Point | 100 °C (approx.) |
| Vapor Pressure | Low at room temperature |
As an accredited 4-Chloro-2,3-Difluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1kg of 4 - chloro - 2,3 - difluoronitrobenzene packaged in a sealed, corrosion - resistant container. |
| Storage | 4 - chloro - 2,3 - difluoronitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials, to prevent leakage. Avoid storing near incompatible substances to minimize the risk of chemical reactions. |
| Shipping | 4 - chloro - 2,3 - difluoronitrobenzene is shipped in sealed, corrosion - resistant containers. It's transported by specialized chemical carriers, adhering to strict safety regulations to prevent spills and ensure safe transit. |
Competitive 4-Chloro-2,3-Difluoronitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a trusted 4-Chloro-2,3-Difluoronitrobenzene manufacturer, we deliver:
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Chloro-2,3-Difluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 4-chloro-2, 3-difluoronitrobenzene
4-Chloro-2,3-difluoronitrobenzene is an organic compound with unique chemical properties. Its chemical activity is quite high, because there are chlorine, fluorine, nitro and other groups attached to the benzene ring.
Nitro is a strong electron-absorbing group, which reduces the electron cloud density of the benzene ring and makes the benzene ring more susceptible to attack by nucleophiles. This property makes 4-chloro-2,3-difluoronitrobenzene active in nucleophilic substitution reactions. For example, when reacting with nucleophiles such as sodium alcohol and amines, chlorine atoms or fluorine atoms can be replaced by nucleophiles to form corresponding substitution products.
Although chlorine and fluorine atoms belong to the same halogen atom, their reactivity varies due to differences in atomic radius and electronegativity. Fluorine atoms have high electronegativity and high carbon-fluorine bond energy. Compared with chlorine atoms, fluorine atom substitution reaction conditions are more demanding. However, under suitable conditions, both can participate in the reaction, providing the possibility for the construction of various organic compounds.
Its chemical stability is relatively poor, in case of high temperature, open flame or strong oxidant, or cause dangerous reactions. When storing and using, it is necessary to strictly follow safety procedures to prevent accidents.
In addition, the physical properties of 4-chloro-2,3-difluoronitrobenzene also affect its chemical reactions, such as solubility, melting point, boiling point, etc. Its solubility determines the feasibility and reaction rate of the reaction in a specific solvent. In conclusion, the chemical properties of 4-chloro-2,3-difluoronitrobenzene are determined by its structure, which makes it widely used in the field of organic synthesis. However, it is necessary to use it with caution and fully consider its reactivity and stability.
Nitro is a strong electron-absorbing group, which reduces the electron cloud density of the benzene ring and makes the benzene ring more susceptible to attack by nucleophiles. This property makes 4-chloro-2,3-difluoronitrobenzene active in nucleophilic substitution reactions. For example, when reacting with nucleophiles such as sodium alcohol and amines, chlorine atoms or fluorine atoms can be replaced by nucleophiles to form corresponding substitution products.
Although chlorine and fluorine atoms belong to the same halogen atom, their reactivity varies due to differences in atomic radius and electronegativity. Fluorine atoms have high electronegativity and high carbon-fluorine bond energy. Compared with chlorine atoms, fluorine atom substitution reaction conditions are more demanding. However, under suitable conditions, both can participate in the reaction, providing the possibility for the construction of various organic compounds.
Its chemical stability is relatively poor, in case of high temperature, open flame or strong oxidant, or cause dangerous reactions. When storing and using, it is necessary to strictly follow safety procedures to prevent accidents.
In addition, the physical properties of 4-chloro-2,3-difluoronitrobenzene also affect its chemical reactions, such as solubility, melting point, boiling point, etc. Its solubility determines the feasibility and reaction rate of the reaction in a specific solvent. In conclusion, the chemical properties of 4-chloro-2,3-difluoronitrobenzene are determined by its structure, which makes it widely used in the field of organic synthesis. However, it is necessary to use it with caution and fully consider its reactivity and stability.
What are the main uses of 4-chloro-2, 3-difluoronitrobenzene
4-Chloro-2,3-difluoronitrobenzene is also an organic compound. It has a wide range of uses and is important in various fields of chemical industry.
First, it can be used to create new pesticides. At present, agriculture has an increasing demand for high-efficiency, low-toxicity and high-selectivity pesticides. 4-Chloro-2,3-difluoronitrobenzene can be transformed into compounds with unique insecticidal, bactericidal or herbicidal properties through specific chemical reactions. By precisely attacking pests and reducing the impact on beneficial organisms and the environment, this compound has made great contributions to agricultural harvest and ecological harmony.
Second, it also has extraordinary performance in the field of pharmaceutical synthesis. In the synthesis of many drugs, this compound is a key intermediate. Its special chemical structure can introduce specific functional groups to help build complex drug molecular structures, so as to develop specific drugs for various diseases, such as cardiovascular diseases, nervous system diseases, etc.
Furthermore, in the field of materials science, 4-chloro-2,3-difluoronitrobenzene can be used as a raw material for the synthesis of special polymer materials. The resulting materials have excellent heat resistance, corrosion resistance, or unique optical and electrical properties, and are widely used in high-end fields such as aerospace and electronic information.
In addition, it also has a place in dye synthesis. Through ingenious reaction design, dyes with bright colors and excellent fastness can be generated to meet the needs of high-quality dyes in textile, printing and dyeing industries.
In short, 4-chloro-2,3-difluoronitrobenzene plays an indispensable role in many fields such as pesticides, medicine, materials, dyes, etc., and promotes the development and progress of various industries.
First, it can be used to create new pesticides. At present, agriculture has an increasing demand for high-efficiency, low-toxicity and high-selectivity pesticides. 4-Chloro-2,3-difluoronitrobenzene can be transformed into compounds with unique insecticidal, bactericidal or herbicidal properties through specific chemical reactions. By precisely attacking pests and reducing the impact on beneficial organisms and the environment, this compound has made great contributions to agricultural harvest and ecological harmony.
Second, it also has extraordinary performance in the field of pharmaceutical synthesis. In the synthesis of many drugs, this compound is a key intermediate. Its special chemical structure can introduce specific functional groups to help build complex drug molecular structures, so as to develop specific drugs for various diseases, such as cardiovascular diseases, nervous system diseases, etc.
Furthermore, in the field of materials science, 4-chloro-2,3-difluoronitrobenzene can be used as a raw material for the synthesis of special polymer materials. The resulting materials have excellent heat resistance, corrosion resistance, or unique optical and electrical properties, and are widely used in high-end fields such as aerospace and electronic information.
In addition, it also has a place in dye synthesis. Through ingenious reaction design, dyes with bright colors and excellent fastness can be generated to meet the needs of high-quality dyes in textile, printing and dyeing industries.
In short, 4-chloro-2,3-difluoronitrobenzene plays an indispensable role in many fields such as pesticides, medicine, materials, dyes, etc., and promotes the development and progress of various industries.
What are the preparation methods of 4-chloro-2, 3-difluoronitrobenzene
There are several ways to prepare 4-chloro-2,3-difluoronitrobenzene. One method is to use 2,3-difluorochlorobenzene as the starting material, so that it can be nitrified with mixed acids (a mixture of nitric acid and sulfuric acid). During the reaction, temperature control is very important, usually at a lower temperature, such as slowly adding mixed acids between 0-10 ° C. If the cap temperature is too high, side reactions will easily occur, resulting in impure products. In this reaction process, the nitric acid of the mixed acid provides nitro positive ions, which attack the benzene ring of 2,3-difluorochlorobenzene and are electrophilically substituted to obtain 4-chloro-2,3-difluoronitrobenzene. After the reaction is completed, the product can be separated by appropriate methods, such as extraction, distillation, etc., to obtain a pure product.
Another method can first make 2,3-difluoronitrobenzene and an appropriate chlorinating agent, such as chlorine gas or chlorine-containing reagents, chlorination reaction in the presence of a catalyst. The catalyst can often be used metal halide, such as iron chloride. During the reaction, attention should also be paid to the regulation of temperature and reaction time. The chlorine atom of the chlorinating agent replaces the hydrogen atom at a specific position on the benzene ring. After this reaction, 4-chloro-2,3-difluoronitrobenzene can also be obtained. After the reaction is completed, the same steps of separation and purification are required to obtain a high-purity target product. These two methods are common methods for preparing 4-chloro-2,3-difluoronitrobenzene, each with its own advantages and disadvantages. The appropriate method should be selected according to the actual situation, such as the availability of raw materials, the level of cost, and the requirements for product purity.
Another method can first make 2,3-difluoronitrobenzene and an appropriate chlorinating agent, such as chlorine gas or chlorine-containing reagents, chlorination reaction in the presence of a catalyst. The catalyst can often be used metal halide, such as iron chloride. During the reaction, attention should also be paid to the regulation of temperature and reaction time. The chlorine atom of the chlorinating agent replaces the hydrogen atom at a specific position on the benzene ring. After this reaction, 4-chloro-2,3-difluoronitrobenzene can also be obtained. After the reaction is completed, the same steps of separation and purification are required to obtain a high-purity target product. These two methods are common methods for preparing 4-chloro-2,3-difluoronitrobenzene, each with its own advantages and disadvantages. The appropriate method should be selected according to the actual situation, such as the availability of raw materials, the level of cost, and the requirements for product purity.
4-Chloro-2, 3-difluoronitrobenzene what are the precautions in storage and transportation
4-Chloro-2,3-difluoronitrobenzene is a commonly used raw material for organic synthesis. When storing and transporting, care should be taken to ensure its safety and everything goes well.
First words storage, this substance should be placed in a cool and well ventilated place. It is easy to cause its chemical properties to be unstable or cause unexpected changes due to heat. And it should be kept away from fires and heat sources to prevent disasters caused by fire candles. The warehouse temperature should not exceed 30 ° C, and the humidity should be controlled in a suitable environment to avoid moisture deterioration.
Furthermore, this product should be stored separately from oxidants, reducing agents, alkalis, etc., and must not be mixed. Due to its strong chemical activity, it comes into contact with various substances or reacts violently, endangering safety. The storage place also needs to be equipped with suitable materials to contain the leakage, just in case.
As for transportation, qualified transportation enterprises and vehicles must be selected. Before transportation, check whether the packaging is in good condition and whether the seal is tight to prevent leakage during transportation. During transportation, it is necessary to ensure that the container is not tipped, leaked or damaged. Driving routes should be avoided in densely populated areas and traffic arteries to prevent accidents. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment.
When loading and unloading, operators must wear protective equipment, pack lightly and unload lightly, and must not operate brutally, resulting in package damage. In case of leakage, quickly evacuate the personnel from the contaminated area to a safe place and isolate them, strictly restricting access. Emergency personnel need to wear self-contained positive pressure breathing apparatus and anti-toxic clothing, and do not let the leakage come into contact with combustible substances. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be built embankment or excavated for containment, and transferred to a tanker or a special collector for recycling or transportation to a waste treatment site for disposal.
The storage and transportation of 4-chloro-2,3-difluoronitrobenzene is related to safety and production. It must not be slack at all. It must be done in accordance with regulations to ensure safety.
First words storage, this substance should be placed in a cool and well ventilated place. It is easy to cause its chemical properties to be unstable or cause unexpected changes due to heat. And it should be kept away from fires and heat sources to prevent disasters caused by fire candles. The warehouse temperature should not exceed 30 ° C, and the humidity should be controlled in a suitable environment to avoid moisture deterioration.
Furthermore, this product should be stored separately from oxidants, reducing agents, alkalis, etc., and must not be mixed. Due to its strong chemical activity, it comes into contact with various substances or reacts violently, endangering safety. The storage place also needs to be equipped with suitable materials to contain the leakage, just in case.
As for transportation, qualified transportation enterprises and vehicles must be selected. Before transportation, check whether the packaging is in good condition and whether the seal is tight to prevent leakage during transportation. During transportation, it is necessary to ensure that the container is not tipped, leaked or damaged. Driving routes should be avoided in densely populated areas and traffic arteries to prevent accidents. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment.
When loading and unloading, operators must wear protective equipment, pack lightly and unload lightly, and must not operate brutally, resulting in package damage. In case of leakage, quickly evacuate the personnel from the contaminated area to a safe place and isolate them, strictly restricting access. Emergency personnel need to wear self-contained positive pressure breathing apparatus and anti-toxic clothing, and do not let the leakage come into contact with combustible substances. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be built embankment or excavated for containment, and transferred to a tanker or a special collector for recycling or transportation to a waste treatment site for disposal.
The storage and transportation of 4-chloro-2,3-difluoronitrobenzene is related to safety and production. It must not be slack at all. It must be done in accordance with regulations to ensure safety.
What are the effects of 4-chloro-2, 3-difluoronitrobenzene on the environment and human health?
4-Chloro-2,3-difluoronitrobenzene is also an organic compound. It may be used in industrial synthesis and other fields, but it has an impact on the environment and human health.
At the environmental end, if this compound is released in nature, it is easy to remain in the environment because of its stable chemical structure and difficult to be degraded by microorganisms. It may diffuse through water, soil and other media, causing disturbance to the surrounding ecology. And it is highly toxic to aquatic organisms, which can damage the ecological balance of water bodies, hinder the survival and reproduction of fish and plankton, and affect the stability of the food chain.
As for human health, 4-chloro-2,3-difluoronitrobenzene is irritating. If people inhale through the respiratory tract, skin contact or take it by mistake, it can cause discomfort. When entering the body through the respiratory tract, it can stab the mucosa of the respiratory tract, causing cough, asthma, breathing difficulties and other diseases; skin contact, or cause skin redness, swelling, itching, burning; if taken by mistake, it can damage the digestive tract, causing nausea, vomiting, abdominal pain, etc. Long-term exposure to this compound may cause mutation and carcinogenesis, because it may affect the normal metabolism and gene expression of human cells, endangering human health.
Therefore, when using and disposing of 4-chloro-2,3-difluoronitrobenzene, be careful and follow strict safety procedures to reduce its harm to the environment and human health.
At the environmental end, if this compound is released in nature, it is easy to remain in the environment because of its stable chemical structure and difficult to be degraded by microorganisms. It may diffuse through water, soil and other media, causing disturbance to the surrounding ecology. And it is highly toxic to aquatic organisms, which can damage the ecological balance of water bodies, hinder the survival and reproduction of fish and plankton, and affect the stability of the food chain.
As for human health, 4-chloro-2,3-difluoronitrobenzene is irritating. If people inhale through the respiratory tract, skin contact or take it by mistake, it can cause discomfort. When entering the body through the respiratory tract, it can stab the mucosa of the respiratory tract, causing cough, asthma, breathing difficulties and other diseases; skin contact, or cause skin redness, swelling, itching, burning; if taken by mistake, it can damage the digestive tract, causing nausea, vomiting, abdominal pain, etc. Long-term exposure to this compound may cause mutation and carcinogenesis, because it may affect the normal metabolism and gene expression of human cells, endangering human health.
Therefore, when using and disposing of 4-chloro-2,3-difluoronitrobenzene, be careful and follow strict safety procedures to reduce its harm to the environment and human health.
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