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4-Chloro-2,5-Dimethybenzene-1-Sulfonyl Chloride
Linshang Chemical
|
HS Code |
877825 |
| Name | 4-Chloro-2,5-Dimethylbenzene-1-Sulfonyl Chloride |
| Chemical Formula | C8H8Cl2O2S |
| Molar Mass | 239.12 g/mol |
| Appearance | Typically a solid |
| Physical State At Room Temp | Solid |
| Solubility | Soluble in some organic solvents |
| Purity | Can vary by source, typically specified as a percentage |
| Hazard Class | Corrosive (due to sulfonyl chloride group) |
As an accredited 4-Chloro-2,5-Dimethybenzene-1-Sulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - chloro - 2,5 - dimethylbenzene - 1 - sulfonyl chloride in a sealed, corrosion - resistant container. |
| Storage | 4 - chloro - 2,5 - dimethylbenzene - 1 - sulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contact with air. Store it separately from incompatible substances like bases, amines, and reducing agents to avoid potential reactions. |
| Shipping | 4 - chloro - 2,5 - dimethylbenzene - 1 - sulfonyl chloride is shipped in well - sealed, corrosion - resistant containers. It's transported with strict adherence to chemical shipping regulations to prevent spills and ensure safety during transit. |
Competitive 4-Chloro-2,5-Dimethybenzene-1-Sulfonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 4-Chloro-2,5-Dimethybenzene-1-Sulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4-chloro-2, 5-dimethybenzene-1-sulfonyl Chloride?
4-Chloro-2,5-dimethylbenzene-1-sulfonyl chloride is an organic compound. It has a wide range of uses and plays a significant role in the field of organic synthesis.
First, it is often used to prepare various sulfonamides. Sulfonamides have many applications in the field of medicine, like some sulfonamides, they have antibacterial effects. By reacting 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride with corresponding amines, sulfonamides with different structures can be prepared, providing key intermediates for the development of new drugs.
Second, it is also used in materials science. It can be used to synthesize polymer materials with specific properties. For example, by reacting with polymer monomers containing reactive groups, a sulfonyl chloride group is introduced into the main chain or side chain of the polymer, thereby changing the solubility, thermal stability and surface properties of the polymer, so that the material can meet the needs of different fields such as electronic devices and coatings.
Furthermore, it can also be used as an important sulfonation agent. Sulfonation reactions are carried out on some organic compounds, introducing sulfonyl groups, thereby changing the physical and chemical properties of substrates. For example, enhancing the hydrophilicity of certain compounds makes it easier to react or apply in the aqueous phase. In the dye industry, sulfonation reactions can improve the solubility and dyeing properties of dyes, and improve the quality and application effect of dyes.
In summary, 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride plays an important role in many fields such as organic synthesis, medicine, materials and dyes, and is of great significance to the development of related industries.
First, it is often used to prepare various sulfonamides. Sulfonamides have many applications in the field of medicine, like some sulfonamides, they have antibacterial effects. By reacting 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride with corresponding amines, sulfonamides with different structures can be prepared, providing key intermediates for the development of new drugs.
Second, it is also used in materials science. It can be used to synthesize polymer materials with specific properties. For example, by reacting with polymer monomers containing reactive groups, a sulfonyl chloride group is introduced into the main chain or side chain of the polymer, thereby changing the solubility, thermal stability and surface properties of the polymer, so that the material can meet the needs of different fields such as electronic devices and coatings.
Furthermore, it can also be used as an important sulfonation agent. Sulfonation reactions are carried out on some organic compounds, introducing sulfonyl groups, thereby changing the physical and chemical properties of substrates. For example, enhancing the hydrophilicity of certain compounds makes it easier to react or apply in the aqueous phase. In the dye industry, sulfonation reactions can improve the solubility and dyeing properties of dyes, and improve the quality and application effect of dyes.
In summary, 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride plays an important role in many fields such as organic synthesis, medicine, materials and dyes, and is of great significance to the development of related industries.
What are the physical properties of 4-chloro-2, 5-dimethybenzene-1-sulfonyl Chloride
4-Chloro-2,5-dimethylbenzene-1-sulfonyl chloride, an organic compound, is very important in the chemical industry. Its physical properties are unique, let me tell them one by one.
Looking at its appearance, under room temperature and pressure, it is mostly white to light yellow crystalline powder. This state is convenient for storage and transportation, and is also conducive to subsequent chemical operations.
As for the melting point, it is about a specific temperature range. The characteristics of the melting point can help chemical workers determine the purity of this product by means of the melting point. Those with high purity have stable and accurate melting points; when the purity is low, the melting point may be deviated, and the melting distance will also change.
In terms of solubility, this compound has good solubility in some organic solvents, such as dichloromethane, chloroform, etc. This property makes it easy to mix with other organic reagents in organic synthesis reactions, which in turn promotes the smooth progress of the reaction. However, in water, its solubility is not good. This point is of great significance for product separation and purification in chemical production. The immiscibility of water and organic solvents can be used for liquid-liquid extraction to achieve the purpose of separation and purification.
Its boiling point also has a specific value. The level of boiling point is closely related to the intermolecular force. High boiling points indicate that the intermolecular force is strong. During the heating process, more energy is required to convert it from liquid to gaseous state. This is particularly critical in separation operations such as distillation. Chemical practitioners can separate it from the mixture by distillation according to the difference in boiling point.
In addition, the density of 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride is also an important physical property. Its density is different from that of water and common organic solvents. This difference can be used as an important basis in the process of liquid-liquid separation. Depending on the density difference, different liquids are stratified to achieve separation.
To sum up, the physical properties of 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride, such as appearance, melting point, solubility, boiling point and density, play an indispensable role in chemical production, organic synthesis, product separation and purification. Only those who are familiar with the physical properties of this substance can be handy in actual operation and achieve the expected chemical production and synthesis purposes.
Looking at its appearance, under room temperature and pressure, it is mostly white to light yellow crystalline powder. This state is convenient for storage and transportation, and is also conducive to subsequent chemical operations.
As for the melting point, it is about a specific temperature range. The characteristics of the melting point can help chemical workers determine the purity of this product by means of the melting point. Those with high purity have stable and accurate melting points; when the purity is low, the melting point may be deviated, and the melting distance will also change.
In terms of solubility, this compound has good solubility in some organic solvents, such as dichloromethane, chloroform, etc. This property makes it easy to mix with other organic reagents in organic synthesis reactions, which in turn promotes the smooth progress of the reaction. However, in water, its solubility is not good. This point is of great significance for product separation and purification in chemical production. The immiscibility of water and organic solvents can be used for liquid-liquid extraction to achieve the purpose of separation and purification.
Its boiling point also has a specific value. The level of boiling point is closely related to the intermolecular force. High boiling points indicate that the intermolecular force is strong. During the heating process, more energy is required to convert it from liquid to gaseous state. This is particularly critical in separation operations such as distillation. Chemical practitioners can separate it from the mixture by distillation according to the difference in boiling point.
In addition, the density of 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride is also an important physical property. Its density is different from that of water and common organic solvents. This difference can be used as an important basis in the process of liquid-liquid separation. Depending on the density difference, different liquids are stratified to achieve separation.
To sum up, the physical properties of 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride, such as appearance, melting point, solubility, boiling point and density, play an indispensable role in chemical production, organic synthesis, product separation and purification. Only those who are familiar with the physical properties of this substance can be handy in actual operation and achieve the expected chemical production and synthesis purposes.
What are the chemical properties of 4-chloro-2, 5-dimethybenzene-1-sulfonyl Chloride
4-Chloro-2,5-dimethylbenzene-1-sulfonyl chloride, which has unique properties and is both chlorine and sulfonyl chloride. Its chlorine atom is active and can participate in the reaction of nucleophilic substitution. Nucleophilic reagents such as alcohols and amines can interact with them, and chlorine atoms are replaced by nucleophilic groups. In the case of alcohols, under the catalysis of bases, chlorine is replaced by alkoxy groups to form corresponding sulfonates. This reaction is commonly used in the synthesis of organic esters.
Sulfonyl chloride groups also have high reactivity. When hydrolyzed, it is converted into sulfonic acid in contact with water. This process can occur under mild conditions, generating 4-chloro-2,5-dimethylbenzenesulfonic acid, which can be used to prepare various sulfonic acid derivatives. When reacted with ammonia or amines, sulfonamides can be formed. This is an important way to prepare sulfonamide-containing structural compounds and is widely used in the fields of medicinal chemistry and materials science.
Because of its chlorine atoms and sulfonyl chloride groups, it is corrosive and irritating to the skin, eyes and respiratory tract. When operating, careful protection is required, and it should be carried out in a well-ventilated environment to avoid direct contact with the human body. The compound is relatively active and should be stored in a dry and cool place to avoid heat and moisture to prevent it from deteriorating or causing dangerous reactions. In the field of organic synthesis, due to its unique chemical properties, it provides important raw materials and means for the synthesis of various and complex organic compounds.
Sulfonyl chloride groups also have high reactivity. When hydrolyzed, it is converted into sulfonic acid in contact with water. This process can occur under mild conditions, generating 4-chloro-2,5-dimethylbenzenesulfonic acid, which can be used to prepare various sulfonic acid derivatives. When reacted with ammonia or amines, sulfonamides can be formed. This is an important way to prepare sulfonamide-containing structural compounds and is widely used in the fields of medicinal chemistry and materials science.
Because of its chlorine atoms and sulfonyl chloride groups, it is corrosive and irritating to the skin, eyes and respiratory tract. When operating, careful protection is required, and it should be carried out in a well-ventilated environment to avoid direct contact with the human body. The compound is relatively active and should be stored in a dry and cool place to avoid heat and moisture to prevent it from deteriorating or causing dangerous reactions. In the field of organic synthesis, due to its unique chemical properties, it provides important raw materials and means for the synthesis of various and complex organic compounds.
What is the synthesis method of 4-chloro-2, 5-dimethybenzene-1-sulfonyl Chloride
The synthesis of 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride is a key issue in the field of organic synthesis. The way of its synthesis is the conventional number method.
First, it can start from 2,5-dimethylbenzene-1-sulfonyl chloride and introduce chlorine atoms through a halogenation reaction. The halogenation method is mostly reacted with chlorine gas or chlorine-containing reagents under suitable conditions. Among them, temperature, catalyst and the proportion of reactants are all important factors affecting the reaction. If the temperature is too high, it may cause side reactions to breed, and the yield is low; if the ratio is not appropriate, it is difficult to achieve the desired effect. The halogenation reagents used, such as N-chlorosuccinimide (NCS), can be selectively halogenated in the presence of specific solvents and catalysts to improve the purity of the target product.
Second, using 4-chloro-2,5-dimethylbenzene as the raw material, the sulfonyl group is first introduced through a sulfonation reaction, and then chlorinated to form a sulfonyl chloride. During sulfonation, concentrated sulfuric acid or fuming sulfuric acid are commonly used. At a specific temperature and reaction time, the sulfonic acid group can be precisely positioned and introduced into the benzene ring. Subsequent chlorination, reagents such as dichlorosulfoxide can be used to convert the sulfonic acid group into sulfonyl chloride. In this process, the choice of solvent is quite important, and its effect on the reaction activity and sel For example, some polar solvents can promote the reaction, but may affect the stability of the product.
Furthermore, other benzene-containing compounds can be used to gradually construct the target molecular structure through multi-step reactions. Although such methods are complicated, under specific conditions, they can effectively avoid some side reactions and improve the yield and purity of the product. Each step of the reaction requires strict control of conditions, such as reaction time, temperature, pH, etc., and fine separation and purification of intermediate products to prevent impurities from accumulating and affecting the quality of the final product.
In conclusion, the synthesis of 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride requires comprehensive consideration of various reaction factors, and the optimal synthesis path is selected according to actual needs and conditions, in order to achieve the purpose of high-efficiency and high-purity synthesis.
First, it can start from 2,5-dimethylbenzene-1-sulfonyl chloride and introduce chlorine atoms through a halogenation reaction. The halogenation method is mostly reacted with chlorine gas or chlorine-containing reagents under suitable conditions. Among them, temperature, catalyst and the proportion of reactants are all important factors affecting the reaction. If the temperature is too high, it may cause side reactions to breed, and the yield is low; if the ratio is not appropriate, it is difficult to achieve the desired effect. The halogenation reagents used, such as N-chlorosuccinimide (NCS), can be selectively halogenated in the presence of specific solvents and catalysts to improve the purity of the target product.
Second, using 4-chloro-2,5-dimethylbenzene as the raw material, the sulfonyl group is first introduced through a sulfonation reaction, and then chlorinated to form a sulfonyl chloride. During sulfonation, concentrated sulfuric acid or fuming sulfuric acid are commonly used. At a specific temperature and reaction time, the sulfonic acid group can be precisely positioned and introduced into the benzene ring. Subsequent chlorination, reagents such as dichlorosulfoxide can be used to convert the sulfonic acid group into sulfonyl chloride. In this process, the choice of solvent is quite important, and its effect on the reaction activity and sel For example, some polar solvents can promote the reaction, but may affect the stability of the product.
Furthermore, other benzene-containing compounds can be used to gradually construct the target molecular structure through multi-step reactions. Although such methods are complicated, under specific conditions, they can effectively avoid some side reactions and improve the yield and purity of the product. Each step of the reaction requires strict control of conditions, such as reaction time, temperature, pH, etc., and fine separation and purification of intermediate products to prevent impurities from accumulating and affecting the quality of the final product.
In conclusion, the synthesis of 4-chloro-2,5-dimethylbenzene-1-sulfonyl chloride requires comprehensive consideration of various reaction factors, and the optimal synthesis path is selected according to actual needs and conditions, in order to achieve the purpose of high-efficiency and high-purity synthesis.
What are the precautions for 4-chloro-2, 5-dimethybenzene-1-sulfonyl Chloride in storage and transportation?
4-Chloro-2,5-dimethylbenzene-1-sulfonyl chloride is a chemical substance, and many matters must be paid attention to during storage and transportation.
First words storage. This chemical is active in nature or should be stored in a cool, dry and well-ventilated place. Because of the cool environment, it can reduce the risk of aggravation of the reaction due to high temperature; dry place, it can avoid contact with water vapor to prevent adverse reactions such as hydrolysis; good ventilation can disperse harmful gases that may escape in time to ensure the safety of the storage environment. And be sure to keep away from fire and heat sources. Open flames and hot topics can easily cause danger, which is an important rule for safety. At the same time, it should be stored separately from oxidizers and alkalis, because the chemical properties of the substance and their substances are contrary, and the co-storage is prone to chemical reactions, resulting in safety accidents. Furthermore, the storage area should be equipped with suitable materials to contain leaks, just in case there is a leak, it can be dealt with in time to avoid pollution expansion.
As for transportation, it should not be ignored. Make sure that the packaging is complete and sealed before transportation. If the packaging is damaged, the chemical is easy to leak, which not only pollutes the environment, but also poses a threat to the transportation personnel. During transportation, it is necessary to drive at a steady speed to avoid bumps and shocks, so as to prevent material leakage caused by damaged packaging. And transport vehicles should be equipped with the appropriate variety and quantity of fire equipment and leakage emergency treatment equipment, if there is an accident on the way, can quickly respond. In addition, transport personnel should be familiar with the dangerous characteristics of the chemical and emergency treatment methods, so that in case of emergencies can be handled calmly and properly to ensure the safety of transportation.
First words storage. This chemical is active in nature or should be stored in a cool, dry and well-ventilated place. Because of the cool environment, it can reduce the risk of aggravation of the reaction due to high temperature; dry place, it can avoid contact with water vapor to prevent adverse reactions such as hydrolysis; good ventilation can disperse harmful gases that may escape in time to ensure the safety of the storage environment. And be sure to keep away from fire and heat sources. Open flames and hot topics can easily cause danger, which is an important rule for safety. At the same time, it should be stored separately from oxidizers and alkalis, because the chemical properties of the substance and their substances are contrary, and the co-storage is prone to chemical reactions, resulting in safety accidents. Furthermore, the storage area should be equipped with suitable materials to contain leaks, just in case there is a leak, it can be dealt with in time to avoid pollution expansion.
As for transportation, it should not be ignored. Make sure that the packaging is complete and sealed before transportation. If the packaging is damaged, the chemical is easy to leak, which not only pollutes the environment, but also poses a threat to the transportation personnel. During transportation, it is necessary to drive at a steady speed to avoid bumps and shocks, so as to prevent material leakage caused by damaged packaging. And transport vehicles should be equipped with the appropriate variety and quantity of fire equipment and leakage emergency treatment equipment, if there is an accident on the way, can quickly respond. In addition, transport personnel should be familiar with the dangerous characteristics of the chemical and emergency treatment methods, so that in case of emergencies can be handled calmly and properly to ensure the safety of transportation.
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