4-Chloro-2-(Chloromethyl)-1-Methoxybenzene
Linshang Chemical
HS Code |
270746 |
Chemical Formula | C8H8Cl2O |
Molecular Weight | 191.05 |
Appearance | Typically a colorless to light - yellow liquid |
Boiling Point | Approximately 260 - 270 °C |
Density | Around 1.25 - 1.3 g/cm³ |
Solubility In Water | Insoluble in water |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether, and dichloromethane |
Vapor Pressure | Low vapor pressure at room temperature |
Flash Point | Relatively high flash point, > 100 °C |
As an accredited 4-Chloro-2-(Chloromethyl)-1-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 4 - chloro - 2 - (chloromethyl)-1 - methoxybenzene in sealed chemical - grade container. |
Storage | 4 - chloro - 2 - (chloromethyl)-1 - methoxybenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air or moisture, which could potentially lead to decomposition or unwanted reactions. |
Shipping | 4 - chloro - 2 - (chloromethyl)-1 - methoxybenzene is shipped in tightly sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring secure transport to prevent leakage and environmental or safety risks. |
Competitive 4-Chloro-2-(Chloromethyl)-1-Methoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 4-Chloro-2-(Chloromethyl)-1-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
The process of organic synthesis, the preparation of many fine chemicals, often rely on this compound as a starting material. The cover contains chlorine atoms and chloromethyl groups in its structure, which are highly reactive and can be used through various chemical reactions, such as nucleophilic substitution reactions, to introduce various functional groups, thereby building a complex and diverse structure of organic molecules.
In the field of pharmaceutical chemistry, this compound is also very important. In the synthesis of many drugs, it will be used to participate in the reaction to build the core structure of the drug molecule, and then endow the drug with specific biological activity and pharmacological properties.
In the field of materials science, 4-chloro-2- (chloromethyl) -1-methoxybenzene may also have its uses. Or it can be used as a raw material to prepare polymer materials with special properties, such as materials with specific electrical and optical properties, through specific reaction processes, to meet the needs of different fields for special materials.
In summary, 4-chloro-2- (chloromethyl) -1-methoxybenzene plays an indispensable role in many fields such as organic synthesis, medicinal chemistry, and materials science, and is of great significance for promoting the development of related fields.
First of all, under room temperature, it is mostly colorless to light yellow liquid. It looks quite fluid, and its texture is clear and there is no appearance of turbidity. This liquid may be slightly shiny under sunlight, just like jade liquid, and it is very agile.
Besides, its melting point is low, and it is difficult to form a solid state under normal ambient temperature. The boiling point is relatively moderate, but the exact value varies slightly according to the purity of the preparation and the experimental conditions. Within a certain temperature range, it can be converted from liquid to gaseous state. The accurate determination of this temperature range is crucial to chemical practice and scientific research.
When it comes to solubility, it has good solubility in organic solvents, such as ethanol, ether, dichloromethane, etc. It can be miscible with various organic solvents to form a uniform solution, just like water and milk, indistinguishable from each other. However, in water, the solubility is very small. Due to the characteristics of its molecular structure, the interaction with water molecules is weak, so it is difficult to dissolve in water, just like oil floating in water, and it is distinct.
Its density is slightly larger than that of water. When placed in water, it will slowly sink, like a pearl falling into water, sinking to the bottom of the water. This density characteristic, in the process of separation and purification, can be an important basis for assisting chemical workers to identify the properties of substances and perform separation techniques.
As for volatility, there is also a certain degree of volatilization. In an open environment, it can be gradually distributed in the air, but its volatilization rate is affected by factors such as temperature and air circulation. The higher the temperature, the smoother the air circulation, the faster the volatilization. This volatility, when stored and used, needs to be paid attention to to prevent its escape and loss or cause safety risks.
In summary, the physical properties of 4-chloro-2- (chloromethyl) -1-methoxybenzene are of great significance in many fields such as chemical industry and scientific research, and are the key to the understanding and application of this compound.
Take 1-methoxy-2-methyl-4-chlorobenzene as the starting material, which can be obtained through appropriate channels. Place it in a specific reaction vessel, add an appropriate amount of initiator, such as azodiisobutyronitrile (AIBN), and introduce chlorine gas to react under light conditions. In this reaction, the methyl group in 1-methoxy-2-methyl-4-chlorobenzene is subjected to the action of chlorine gas, initiator and light, and undergoes a free radical substitution reaction. The hydrogen atom on the methyl group is gradually replaced by the chlorine atom, resulting in the formation of 4-chloro-2- (chloromethyl) -1-methoxybenzene.
During the reaction process, close attention should be paid to the control of the reaction conditions. The temperature should not be too high or too low. If it is too high, the side reactions will increase, and if it is too low, the reaction rate will be too slow. The light intensity should also be moderate to ensure that the initiator can effectively initiate free radical reactions. At the same time, the amount of chlorine gas introduced needs to be precisely controlled. Excessive amounts will lead to the formation of polychlorinated by-products, and if it is too small, the reaction will be incomplete.
After the reaction is completed, distillation, extraction, column chromatography and other separation and purification methods can be used to obtain pure 4-chloro-2- (chloromethyl) -1-methoxybenzene. Distillation can be preliminarily separated according to the difference in the boiling point of each substance; extraction can take advantage of the different solubility of the target product in different solvents to extract it from the reaction mixture system; column chromatography can be further separated and purified to obtain high-purity products.
First words storage. This compound should be stored in a cool, dry and well-ventilated place. It covers its properties or is unstable due to changes in temperature and humidity, and it is easy to deteriorate in a high temperature and humid place. And it must be kept away from fires and heat sources to prevent the risk of fire. Because of its flammability, it may cause violent reactions in case of open flames and hot topics.
Furthermore, the storage place should be separated from oxidants, acids, bases, etc., and must not be mixed. Due to its active chemical properties, it encounters various substances or reacts chemically, causing potential safety hazards. If it encounters strong oxidants, there is a risk of explosion.
As for transportation, caution is also required. Before transportation, make sure that the packaging is complete and sealed. Packaging materials should be able to withstand general collisions and vibrations, and have the property of preventing leakage. During transportation, the speed should be slow to avoid sudden braking and severe turbulence to prevent package damage.
Transportation vehicles must be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. If a leak occurs on the way, it can be dealt with in time. Escort personnel should also be familiar with the properties of this compound and emergency treatment methods to ensure the safety of transportation.
In summary, 4-chloro-2- (chloromethyl) -1-methoxybenzene requires careful attention during storage and transportation, such as temperature and humidity control, fire source avoidance, material isolation, packaging integrity, and emergency equipment, in order to ensure its safety and avoid accidents.
In the environment, this compound may be difficult to degrade naturally due to its certain chemical stability, so it accumulates in the environment. It persists in soil, water and other media, or disturbs the structure and function of soil microbial communities, thereby affecting the normal operation of soil ecosystems, causing changes in soil fertility, material circulation and other processes. In water bodies, it may pose a threat to aquatic organisms. If aquatic animals are exposed to this compound, it may cause damage to their physiological functions, such as stunted growth and development, reduced reproductive ability, and even cause death. And it may have a biomagnification effect in the food chain, from lower organisms to higher organisms, the concentration increases gradually, causing serious impact on the balance of the entire aquatic ecosystem.
As for the human health end, this compound may invade the human body through various routes. Through respiration, it can enter the lungs from the air and then spread to the whole body; through skin contact, it can penetrate the skin barrier; or through ingestion of contaminated food or water, it can enter the human body through the digestive system. After entering the body, it may cause harm to multiple systems of the human body. For the nervous system, it may interfere with the transmission of neurotransmitters, causing headaches, dizziness, fatigue, etc., long-term exposure, or damage cognitive and memory functions. On the immune system, or weaken the activity of immune cells, reduce the body's resistance to pathogens, and increase the risk of disease. And because it contains chlorine and other functional groups, or has potential carcinogenicity, long-term exposure may increase the risk of human cancer.
Therefore, 4-chloro-2- (chloromethyl) -1-methoxybenzene should be given high attention. During its production and use, proper protection and handling measures must be taken to reduce its harm to the environment and human health.

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