Linshang Chemical
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4-Chloro-2-Iodo-1-(Trifluoromethyl)Benzene
Linshang Chemical
|
HS Code |
920420 |
| Chemical Formula | C7H3ClF3I |
| Molecular Weight | 320.45 |
| Physical State | May be liquid or solid depending on temperature |
| Solubility In Water | Very low, as it is a non - polar organic compound |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform, etc. |
As an accredited 4-Chloro-2-Iodo-1-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - chloro - 2 - iodo - 1 - (trifluoromethyl)benzene packaged in a sealed glass bottle. |
| Storage | 4 - chloro - 2 - iodo - 1 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container to prevent leakage and vapor escape. Due to its potentially hazardous nature, store it in accordance with local regulations for chemical storage. |
| Shipping | 4 - chloro - 2 - iodo - 1 - (trifluoromethyl)benzene is shipped in specialized, leak - proof containers. Shipment adheres to strict chemical transportation regulations, ensuring safe transit to prevent any potential hazards. |
Competitive 4-Chloro-2-Iodo-1-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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What is the main use of 4-chloro-2-iodo-1- (trifluoromethyl) benzene?
4-Chloro-2-iodine-1- (trifluoromethyl) benzene, this is an organic compound. It has a wide range of uses and is a crucial intermediate in the field of organic synthesis.
First, in the field of pharmaceutical chemistry, it is often used as a key starting material. Due to the presence of chlorine, iodine and trifluoromethyl in the molecule, it is endowed with unique chemical properties and spatial structure. With this property, it can participate in many organic reactions, such as nucleophilic substitution reactions, to construct various biologically active compound structures, thereby assisting in the research and development of new drugs.
Second, in the field of materials science, it also shows unique value. Because of its special functional groups, it can be used to prepare materials with special properties. For example, when synthesizing some functional polymer materials, the introduction of this compound may endow the material with good solubility, thermal stability, or even special optical and electrical properties to meet the special needs of the material in different scenarios.
Third, it is also indispensable in pesticide chemistry. As an important intermediate in the synthesis of new pesticides, it can be transformed through specific reactions to create pesticide products with high insecticidal, bactericidal or herbicidal activities. Its special structure may enhance the specificity and affinity of pesticides and target biological interactions, enhance the efficacy of pesticides, and reduce adverse effects on the environment.
In conclusion, 4-chloro-2-iodine-1- (trifluoromethyl) benzene has important uses in many fields related to organic synthesis, and plays a pivotal role in promoting the development of drugs, materials, pesticides and other industries.
First, in the field of pharmaceutical chemistry, it is often used as a key starting material. Due to the presence of chlorine, iodine and trifluoromethyl in the molecule, it is endowed with unique chemical properties and spatial structure. With this property, it can participate in many organic reactions, such as nucleophilic substitution reactions, to construct various biologically active compound structures, thereby assisting in the research and development of new drugs.
Second, in the field of materials science, it also shows unique value. Because of its special functional groups, it can be used to prepare materials with special properties. For example, when synthesizing some functional polymer materials, the introduction of this compound may endow the material with good solubility, thermal stability, or even special optical and electrical properties to meet the special needs of the material in different scenarios.
Third, it is also indispensable in pesticide chemistry. As an important intermediate in the synthesis of new pesticides, it can be transformed through specific reactions to create pesticide products with high insecticidal, bactericidal or herbicidal activities. Its special structure may enhance the specificity and affinity of pesticides and target biological interactions, enhance the efficacy of pesticides, and reduce adverse effects on the environment.
In conclusion, 4-chloro-2-iodine-1- (trifluoromethyl) benzene has important uses in many fields related to organic synthesis, and plays a pivotal role in promoting the development of drugs, materials, pesticides and other industries.
What are the physical properties of 4-chloro-2-iodo-1- (trifluoromethyl) benzene
4-Chloro-2-iodine-1- (trifluoromethyl) benzene, this is an organic compound. Its physical properties are quite critical and are related to many practical applications.
First, its appearance is usually colorless to light yellow liquid or solid, and the specific shape varies according to temperature and environmental conditions. Under normal temperature and pressure, or in a liquid state, it has a certain fluidity, and it is clear and transparent in appearance; if the temperature decreases, or it condenses into a solid, the appearance is crystalline.
Besides the melting point and boiling point, the melting point varies depending on the precise measurement conditions and is roughly in a specific low temperature range. The intermolecular forces and structural characteristics of this compound cause its melting point to have a certain value. The boiling point also depends on the molecular structure. Due to the existence of trifluoromethyl groups, the polarity of molecules changes and intermolecular interactions are affected, so the boiling point is in the corresponding temperature range. At this temperature, the compound changes from liquid to gaseous state.
Its density may be different from that of common organic solvents. Due to the presence of chlorine, iodine and trifluoromethyl groups, the molecular weight increases, and the density is generally greater than that of water. It is placed in water or sinks to the bottom.
In terms of solubility, the compound has good solubility in organic solvents, such as common ether, dichloromethane, etc. Due to the principle of similarity and phase dissolution, its organic structure is similar to that of organic solvents, so it can be well miscible; however, its solubility in water is poor, because its molecular polarity is quite different from that of water molecules, it is difficult to form a good interaction with water.
In addition, the volatility of the compound is relatively moderate, neither extremely volatile nor extremely difficult to volatilize. At a certain level, it will slowly evaporate into the air in an open environment.
The physical properties of this compound are of great significance in the fields of organic synthesis and materials science. Researchers need to be familiar with these properties in order to use them reasonably in experiments and production.
First, its appearance is usually colorless to light yellow liquid or solid, and the specific shape varies according to temperature and environmental conditions. Under normal temperature and pressure, or in a liquid state, it has a certain fluidity, and it is clear and transparent in appearance; if the temperature decreases, or it condenses into a solid, the appearance is crystalline.
Besides the melting point and boiling point, the melting point varies depending on the precise measurement conditions and is roughly in a specific low temperature range. The intermolecular forces and structural characteristics of this compound cause its melting point to have a certain value. The boiling point also depends on the molecular structure. Due to the existence of trifluoromethyl groups, the polarity of molecules changes and intermolecular interactions are affected, so the boiling point is in the corresponding temperature range. At this temperature, the compound changes from liquid to gaseous state.
Its density may be different from that of common organic solvents. Due to the presence of chlorine, iodine and trifluoromethyl groups, the molecular weight increases, and the density is generally greater than that of water. It is placed in water or sinks to the bottom.
In terms of solubility, the compound has good solubility in organic solvents, such as common ether, dichloromethane, etc. Due to the principle of similarity and phase dissolution, its organic structure is similar to that of organic solvents, so it can be well miscible; however, its solubility in water is poor, because its molecular polarity is quite different from that of water molecules, it is difficult to form a good interaction with water.
In addition, the volatility of the compound is relatively moderate, neither extremely volatile nor extremely difficult to volatilize. At a certain level, it will slowly evaporate into the air in an open environment.
The physical properties of this compound are of great significance in the fields of organic synthesis and materials science. Researchers need to be familiar with these properties in order to use them reasonably in experiments and production.
What are the synthesis methods of 4-chloro-2-iodo-1- (trifluoromethyl) benzene
The synthesis of 4-chloro-2-iodine-1- (trifluoromethyl) benzene is a subject of considerable interest in organic synthetic chemistry. There are several common synthetic routes.
One of them can be started from benzene derivatives containing trifluoromethyl. First, chlorine atoms are introduced at specific positions on the benzene ring with suitable halogenating reagents, such as chlorine-containing halogenating agents, under specific reaction conditions. This process requires careful control of reaction temperature, time and reagent dosage to ensure that chlorine atoms are accurately replaced at the target position. Then, a suitable iodization reagent is selected, and in an appropriate reaction system, the iodine atom is substituted to a predetermined position, so as to obtain the target product 4-chloro-2-iodine-1- (trifluoromethyl) benzene.
Second, the strategy of gradually constructing the benzene ring can also be adopted. First prepare an intermediate containing trifluoromethyl, which may be a chain organic compound. Through a series of organic reactions, such as nucleophilic substitution and addition, the benzene ring structure is gradually constructed. In the process of constructing the benzene ring, chlorine atoms and iodine atoms are introduced in sequence. Although this method is more complicated, it has many advantages for precisely controlling the position and reaction selectivity of the substituents.
Furthermore, the catalytic reaction path is also one of the methods for synthesizing this compound. Specific catalysts, such as metal catalysts, are selected to guide the reactant molecules to react according to a specific reaction mechanism. Under the action of the catalyst, the reactants containing chlorine, iodine and trifluoromethyl are coupled to directly generate 4-chloro-2-iodine-1 - (trifluoromethyl) benzene. This path usually requires fine optimization of the type, dosage and reaction conditions of the catalyst to improve the reaction efficiency and product yield.
All the above synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to weigh and choose the most suitable synthesis path according to many factors such as the availability of reactants, reaction cost, and purity requirements of target products.
One of them can be started from benzene derivatives containing trifluoromethyl. First, chlorine atoms are introduced at specific positions on the benzene ring with suitable halogenating reagents, such as chlorine-containing halogenating agents, under specific reaction conditions. This process requires careful control of reaction temperature, time and reagent dosage to ensure that chlorine atoms are accurately replaced at the target position. Then, a suitable iodization reagent is selected, and in an appropriate reaction system, the iodine atom is substituted to a predetermined position, so as to obtain the target product 4-chloro-2-iodine-1- (trifluoromethyl) benzene.
Second, the strategy of gradually constructing the benzene ring can also be adopted. First prepare an intermediate containing trifluoromethyl, which may be a chain organic compound. Through a series of organic reactions, such as nucleophilic substitution and addition, the benzene ring structure is gradually constructed. In the process of constructing the benzene ring, chlorine atoms and iodine atoms are introduced in sequence. Although this method is more complicated, it has many advantages for precisely controlling the position and reaction selectivity of the substituents.
Furthermore, the catalytic reaction path is also one of the methods for synthesizing this compound. Specific catalysts, such as metal catalysts, are selected to guide the reactant molecules to react according to a specific reaction mechanism. Under the action of the catalyst, the reactants containing chlorine, iodine and trifluoromethyl are coupled to directly generate 4-chloro-2-iodine-1 - (trifluoromethyl) benzene. This path usually requires fine optimization of the type, dosage and reaction conditions of the catalyst to improve the reaction efficiency and product yield.
All the above synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to weigh and choose the most suitable synthesis path according to many factors such as the availability of reactants, reaction cost, and purity requirements of target products.
What should be paid attention to when storing 4-chloro-2-iodo-1- (trifluoromethyl) benzene?
4-Chloro-2-iodine-1- (trifluoromethyl) benzene, when stored, many matters must not be ignored.
This material is lively and very sensitive to temperature and humidity. If the temperature is high, its properties are volatile and the quality is damaged. Therefore, if stored in a cool place, the room temperature should be controlled between 15 and 25 degrees Celsius. If the temperature is too high, the molecular movement will be dramatic, or chemical reactions will be induced, which will damage its purity. Humidity is also critical. If it is wet, it can cause deliquescence or react with water vapor. It should be stored in a dry place, and the humidity should be controlled at 40% to 60%.
And this substance is toxic and corrosive to a certain extent, and it needs to be prevented from leaking when stored. The container should be made of corrosion-resistant materials, such as special glass or specific plastics, and should be tightly sealed to prevent escape. The label should state its name, nature and hazard to make it clear to people at a glance.
It is also an organic halide, which is easy to react with other substances. Therefore, it cannot be co-stored with strong oxidants and strong bases. When the oxidant encounters it, it may cause severe oxidation reactions; when the alkali encounters it, it may also cause chemical reactions, which can be dangerous. When placed separately, each has its own place.
When handling, be careful. Handle with care to avoid impact and vibration, and prevent the container from being damaged and causing material leakage. In addition, the storage of 4-chloro-2-iodine-1- (trifluoromethyl) benzene, temperature and humidity, containers, compatibility, handling and ventilation should be paid attention to to to ensure its safety and quality.
This material is lively and very sensitive to temperature and humidity. If the temperature is high, its properties are volatile and the quality is damaged. Therefore, if stored in a cool place, the room temperature should be controlled between 15 and 25 degrees Celsius. If the temperature is too high, the molecular movement will be dramatic, or chemical reactions will be induced, which will damage its purity. Humidity is also critical. If it is wet, it can cause deliquescence or react with water vapor. It should be stored in a dry place, and the humidity should be controlled at 40% to 60%.
And this substance is toxic and corrosive to a certain extent, and it needs to be prevented from leaking when stored. The container should be made of corrosion-resistant materials, such as special glass or specific plastics, and should be tightly sealed to prevent escape. The label should state its name, nature and hazard to make it clear to people at a glance.
It is also an organic halide, which is easy to react with other substances. Therefore, it cannot be co-stored with strong oxidants and strong bases. When the oxidant encounters it, it may cause severe oxidation reactions; when the alkali encounters it, it may also cause chemical reactions, which can be dangerous. When placed separately, each has its own place.
When handling, be careful. Handle with care to avoid impact and vibration, and prevent the container from being damaged and causing material leakage. In addition, the storage of 4-chloro-2-iodine-1- (trifluoromethyl) benzene, temperature and humidity, containers, compatibility, handling and ventilation should be paid attention to to to ensure its safety and quality.
What are the environmental effects of 4-chloro-2-iodo-1- (trifluoromethyl) benzene?
4-Chloro-2-iodine-1- (trifluoromethyl) benzene, its impact on the environment cannot be ignored. This compound contains groups such as chlorine, iodine and trifluoromethyl, which have different properties and complex behaviors in the environment.
Chlorine atoms are active. When 4-chloro-2-iodine-1- (trifluoromethyl) benzene is released into the environment, the chlorine atoms may be separated by chemical reactions and combined with surrounding substances. This process may change the composition of surrounding chemicals, causing changes in the chemical balance of the environment. For example, it may combine with metal ions in water to form new compounds, which affect the migration and transformation of substances in the water body.
Iodine also has its characteristics. Iodine is essential for organisms in ecosystems, but the form of iodine in this compound is special. Its entry into the environment may interfere with the normal uptake and metabolism of iodine by organisms. For aquatic organisms, it may cause disorders of physiological processes related to iodine metabolism such as the thyroid gland, which in turn affect individual growth, development and reproduction.
As for trifluoromethyl, it contains fluoride and is highly stable and hydrophobic. This makes the compound difficult to degrade in the environment and easy to persist. And the existence of trifluoromethyl may change the physical and chemical properties of the compound, such as solubility, volatility, etc. Due to its hydrophobicity, it is easy to adsorb on the surface of soil particles or organic substances, reduce the diffusion in water bodies, and accumulate in specific environmental areas, posing a potential threat to local ecology.
In addition, 4-chloro-2-iodine-1 - (trifluoromethyl) benzene is toxic to organisms as a whole. Its entry into organisms or interaction with biological macromolecules such as proteins and nucleic acids can interfere with normal biochemical reactions in organisms, damage cell functions, and endanger biological survival. In the food chain, its concentration may increase due to biological enrichment, causing greater harm to high-trophic organisms.
In conclusion, 4-chloro-2-iodine-1- (trifluoromethyl) benzene has a wide and complex impact on the environment, which is related to chemical balance, biological metabolism and ecological security. It should be treated with caution and studied in detail to identify its harm and seek countermeasures.
Chlorine atoms are active. When 4-chloro-2-iodine-1- (trifluoromethyl) benzene is released into the environment, the chlorine atoms may be separated by chemical reactions and combined with surrounding substances. This process may change the composition of surrounding chemicals, causing changes in the chemical balance of the environment. For example, it may combine with metal ions in water to form new compounds, which affect the migration and transformation of substances in the water body.
Iodine also has its characteristics. Iodine is essential for organisms in ecosystems, but the form of iodine in this compound is special. Its entry into the environment may interfere with the normal uptake and metabolism of iodine by organisms. For aquatic organisms, it may cause disorders of physiological processes related to iodine metabolism such as the thyroid gland, which in turn affect individual growth, development and reproduction.
As for trifluoromethyl, it contains fluoride and is highly stable and hydrophobic. This makes the compound difficult to degrade in the environment and easy to persist. And the existence of trifluoromethyl may change the physical and chemical properties of the compound, such as solubility, volatility, etc. Due to its hydrophobicity, it is easy to adsorb on the surface of soil particles or organic substances, reduce the diffusion in water bodies, and accumulate in specific environmental areas, posing a potential threat to local ecology.
In addition, 4-chloro-2-iodine-1 - (trifluoromethyl) benzene is toxic to organisms as a whole. Its entry into organisms or interaction with biological macromolecules such as proteins and nucleic acids can interfere with normal biochemical reactions in organisms, damage cell functions, and endanger biological survival. In the food chain, its concentration may increase due to biological enrichment, causing greater harm to high-trophic organisms.
In conclusion, 4-chloro-2-iodine-1- (trifluoromethyl) benzene has a wide and complex impact on the environment, which is related to chemical balance, biological metabolism and ecological security. It should be treated with caution and studied in detail to identify its harm and seek countermeasures.
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