Linshang Chemical
PRODUCTS
4-Chloro-2-Methyl-1-Nitrobenzene
Linshang Chemical
|
HS Code |
310817 |
| Chemical Formula | C7H6ClNO2 |
| Molecular Weight | 171.58 |
| Appearance | Yellow to brown solid |
| Boiling Point | 257 - 258 °C |
| Melting Point | 38 - 40 °C |
| Density | 1.334 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Odor | Characteristic odor |
| Flash Point | 112 °C |
| Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 4-Chloro-2-Methyl-1-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - kg bottle of 4 - chloro - 2 - methyl - 1 - nitrobenzene, well - sealed for chemical storage. |
| Storage | 4 - chloro - 2 - methyl - 1 - nitrobenzene should be stored in a cool, well - ventilated area, away from heat and ignition sources. Keep it in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and bases to avoid potential reactions. Follow proper safety regulations for handling and storage of this hazardous chemical. |
| Shipping | 4 - chloro - 2 - methyl - 1 - nitrobenzene is a hazardous chemical. It should be shipped in properly labeled, leak - proof containers. Follow strict regulations, use appropriate packaging materials, and ensure proper handling during transit to prevent spills and ensure safety. |
Competitive 4-Chloro-2-Methyl-1-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Chloro-2-Methyl-1-Nitrobenzene in China?
As a trusted 4-Chloro-2-Methyl-1-Nitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Chloro-2-Methyl-1-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4-chloro-2-methyl-1-nitrobenzene?
4-Chloro-2-methyl-1-nitrobenzene is a crucial intermediate in the field of organic synthesis. It has a wide range of uses and has key applications in many industries such as medicine, pesticides, dyes, etc.
In the field of medicine, this compound can be used as a starting material for the synthesis of specific drugs. Due to the chlorine atoms, methyl and nitro groups attached to the benzene ring, it is endowed with unique chemical activity and spatial structure, which is suitable for participating in a variety of organic reactions. After a series of transformations, complex molecular structures with specific pharmacological activities are constructed, and then used to create new drugs.
In the pesticide industry, 4-chloro-2-methyl-1-nitrobenzene is also an important synthesis intermediate. By reacting with other organic reagents, pesticide components with insecticidal, bactericidal or herbicidal activities can be generated. Its structural properties can enable it to interact with specific biomacromolecules in pests and pathogens, interfering with their normal physiological processes, and achieving the purpose of preventing and controlling pests.
In the dye industry, this substance also plays an important role. By chemically modifying it, chromophore or chromophore groups can be introduced to prepare dyes with rich colors and excellent properties. The substituents on the benzene ring have a significant impact on the color, stability and dyeing properties of dyes. The rational design is based on the synthesis route of 4-chloro-2-methyl-1-nitrobenzene, and dye products that meet different needs can be obtained.
In short, 4-chloro-2-methyl-1-nitrobenzene is a key intermediate in many industrial fields due to its unique molecular structure and chemical properties, which is of great significance to promote the development of related industries.
In the field of medicine, this compound can be used as a starting material for the synthesis of specific drugs. Due to the chlorine atoms, methyl and nitro groups attached to the benzene ring, it is endowed with unique chemical activity and spatial structure, which is suitable for participating in a variety of organic reactions. After a series of transformations, complex molecular structures with specific pharmacological activities are constructed, and then used to create new drugs.
In the pesticide industry, 4-chloro-2-methyl-1-nitrobenzene is also an important synthesis intermediate. By reacting with other organic reagents, pesticide components with insecticidal, bactericidal or herbicidal activities can be generated. Its structural properties can enable it to interact with specific biomacromolecules in pests and pathogens, interfering with their normal physiological processes, and achieving the purpose of preventing and controlling pests.
In the dye industry, this substance also plays an important role. By chemically modifying it, chromophore or chromophore groups can be introduced to prepare dyes with rich colors and excellent properties. The substituents on the benzene ring have a significant impact on the color, stability and dyeing properties of dyes. The rational design is based on the synthesis route of 4-chloro-2-methyl-1-nitrobenzene, and dye products that meet different needs can be obtained.
In short, 4-chloro-2-methyl-1-nitrobenzene is a key intermediate in many industrial fields due to its unique molecular structure and chemical properties, which is of great significance to promote the development of related industries.
What are the physical properties of 4-chloro-2-methyl-1-nitrobenzene?
4-Chloro-2-methyl-1-nitrobenzene is a kind of organic compound. Its physical properties are particularly important and are related to various chemical applications.
Looking at its properties, at room temperature, it is mostly in a light yellow to brown crystalline shape, just like the accumulation of delicate sand grains, and like a carved crystal block, with a unique appearance. The melting point of this substance is about 32-35 ° C. When the temperature rises to this range, the original solid state of 4-chloro-2-methyl-1-nitrobenzene will gradually melt into a flowing liquid like ice in warm spring, showing the wonderful change of matter from solid to liquid.
As for the boiling point, it is about 246 ° C. When the temperature reaches this height, the substance in the liquid state will be like evaporated water vapor and dissipate into a gaseous state. The characteristics of this boiling point are quite instructive in the process of separation and purification.
Furthermore, the density of 4-chloro-2-methyl-1-nitrobenzene is about 1.32 g/cm3. Taking water as a reference, the density of water is 1 g/cm3, so its density is higher than that of water. If it is placed in a container with water, it will sink to the bottom like a stone and settle under the water layer.
In terms of solubility, it is slightly soluble in water, just like a shy guest. It is only dispersed in a small amount in water, and it is difficult to blend with water. However, in organic solvents such as ethanol, ether, and acetone, they can be closely related to each other and dissolve into one. This difference in solubility can be used as a key basis for the extraction and separation of substances in chemical production.
In addition, 4-chloro-2-methyl-1-nitrobenzene has a certain volatility. In the air, it will slowly emit its molecules. Although it is not easily detectable, it can be perceived under long-term exposure. And its smell is unique, although it is difficult to describe accurately, it can give people a distinct olfactory impression.
All these physical properties are indispensable references in many fields such as organic synthesis, pharmaceutical manufacturing, dye preparation, etc. They are crucial to the process of reaction and the quality of products.
Looking at its properties, at room temperature, it is mostly in a light yellow to brown crystalline shape, just like the accumulation of delicate sand grains, and like a carved crystal block, with a unique appearance. The melting point of this substance is about 32-35 ° C. When the temperature rises to this range, the original solid state of 4-chloro-2-methyl-1-nitrobenzene will gradually melt into a flowing liquid like ice in warm spring, showing the wonderful change of matter from solid to liquid.
As for the boiling point, it is about 246 ° C. When the temperature reaches this height, the substance in the liquid state will be like evaporated water vapor and dissipate into a gaseous state. The characteristics of this boiling point are quite instructive in the process of separation and purification.
Furthermore, the density of 4-chloro-2-methyl-1-nitrobenzene is about 1.32 g/cm3. Taking water as a reference, the density of water is 1 g/cm3, so its density is higher than that of water. If it is placed in a container with water, it will sink to the bottom like a stone and settle under the water layer.
In terms of solubility, it is slightly soluble in water, just like a shy guest. It is only dispersed in a small amount in water, and it is difficult to blend with water. However, in organic solvents such as ethanol, ether, and acetone, they can be closely related to each other and dissolve into one. This difference in solubility can be used as a key basis for the extraction and separation of substances in chemical production.
In addition, 4-chloro-2-methyl-1-nitrobenzene has a certain volatility. In the air, it will slowly emit its molecules. Although it is not easily detectable, it can be perceived under long-term exposure. And its smell is unique, although it is difficult to describe accurately, it can give people a distinct olfactory impression.
All these physical properties are indispensable references in many fields such as organic synthesis, pharmaceutical manufacturing, dye preparation, etc. They are crucial to the process of reaction and the quality of products.
What is the chemistry of 4-chloro-2-methyl-1-nitrobenzene?
4-Chloro-2-methyl-1-nitrobenzene, this is an organic compound. Its chemical properties are unique, with the characteristics of halogenated aromatics and nitro compounds.
Looking at its structure, both chlorine atoms and methyl groups are connected to the benzene ring, and the nitro group is also at a specific position. The presence of chlorine atoms changes the electron cloud density of the benzene ring, making it unique in nucleophilic substitution reactions. In this reaction, the chlorine atom can be replaced by other nucleophilic reagents. In case of a strong nucleophilic reagent, the halogen atom leaves and the nucleophilic reagent takes its place.
methyl is attached to the benzene ring, which is the power supply group, which can increase the density of the electron cloud in the ortho-para of the benzene ring. In the electrophilic substitution reaction, it has a significant impact on the reaction check point and activity. Due to its power supply effect, the electrophilic substitution reaction is prone to occur in the methyl ortho-para.
Nitro is a strong electron-absorbing group, which not only reduces the electron cloud density of the benzene ring significantly, weakens the activity of the electrophilic substitution reaction of the benzene ring, but also enhances the molecular polarity. In the reduction reaction, the nitro group can be gradually converted into other groups such as amino groups, showing rich
In addition, 4-chloro-2-methyl-1-nitrophenyl groups interact with each other in the structure, and the chemical stability has a certain range. Under extreme conditions such as high temperature and strong acid and alkali, the molecular structure may change, triggering various chemical reactions, showing a variety of chemical behaviors, and is widely used in the field of organic synthesis.
Looking at its structure, both chlorine atoms and methyl groups are connected to the benzene ring, and the nitro group is also at a specific position. The presence of chlorine atoms changes the electron cloud density of the benzene ring, making it unique in nucleophilic substitution reactions. In this reaction, the chlorine atom can be replaced by other nucleophilic reagents. In case of a strong nucleophilic reagent, the halogen atom leaves and the nucleophilic reagent takes its place.
methyl is attached to the benzene ring, which is the power supply group, which can increase the density of the electron cloud in the ortho-para of the benzene ring. In the electrophilic substitution reaction, it has a significant impact on the reaction check point and activity. Due to its power supply effect, the electrophilic substitution reaction is prone to occur in the methyl ortho-para.
Nitro is a strong electron-absorbing group, which not only reduces the electron cloud density of the benzene ring significantly, weakens the activity of the electrophilic substitution reaction of the benzene ring, but also enhances the molecular polarity. In the reduction reaction, the nitro group can be gradually converted into other groups such as amino groups, showing rich
In addition, 4-chloro-2-methyl-1-nitrophenyl groups interact with each other in the structure, and the chemical stability has a certain range. Under extreme conditions such as high temperature and strong acid and alkali, the molecular structure may change, triggering various chemical reactions, showing a variety of chemical behaviors, and is widely used in the field of organic synthesis.
What is the preparation method of 4-chloro-2-methyl-1-nitrobenzene?
4-Chloro-2-methyl-1-nitrobenzene is an organic compound. Its preparation method often follows various organic synthesis methods.
One method can start with 2-methyl-1-nitrobenzene. First, 2-methyl-1-nitrobenzene is chlorinated with a chlorine source, such as chlorine ($Cl_2 $), in the presence of a suitable catalyst. The catalyst is often iron powder ($Fe $) or anhydrous ferric trichloride ($FeCl_3 $). During the reaction, chlorine gas undergoes an electrophilic substitution reaction with the phenyl ring in 2-methyl-1-nitrobenzene. Due to the fact that nitro is an meta-locator and methyl is an ortho-para-locator, the two work together to make the chlorine atom mainly replace the ortho-site of methyl to obtain 4-chloro-2-methyl-1-nitrobenzene. The chemical equation of the reaction is roughly as follows: $C_7H_7NO_2 + Cl_2\ xrightarrow [] {Fe or FeCl_3} C_7H_6ClNO_2 + HCl $.
Another method, or 4-chloro-2-methylbenzene can be used as the raw material. Let it be nitrified with nitrate sources, such as mixed acids of concentrated nitric acid ($HNO_3 $) and concentrated sulfuric acid ($H_2SO_4 $). In the reaction of concentrated sulfuric acid, one is used as a dehydrating agent, and the other is to protonate nitric acid and enhance its electrophilic ability. During the reaction, the nitro positive ion attacks the benzene ring. Due to the positioning effect of the methyl group, the nitro group mainly enters the ortho-position of the methyl group, so 4-chloro-2-methyl-1-nitrobenzene is obtained. The chemical equation of the reaction is probably: $C_7H_7Cl + HNO_3\ xrightarrow [] {H_2SO_4} C_7H_6ClNO_2 + H_2O $. When preparing
, pay attention to the conditions of the reaction. The temperature depends on the rate of reaction and the selectivity of the product. In the chlorination reaction, the temperature is too high, which may cause the formation of polychlorinated substitutes; in the nitrification reaction, the temperature is inappropriate, or by-products are produced. And the solvent of the reaction also needs to be carefully selected, which affects the solubility and reaction mechanism of the reactants. At the end of the reaction, the product often needs to be separated and purified, such as distillation, recrystallization, column chromatography, etc., to obtain pure 4-chloro-2-methyl-1-nitrobenzene.
One method can start with 2-methyl-1-nitrobenzene. First, 2-methyl-1-nitrobenzene is chlorinated with a chlorine source, such as chlorine ($Cl_2 $), in the presence of a suitable catalyst. The catalyst is often iron powder ($Fe $) or anhydrous ferric trichloride ($FeCl_3 $). During the reaction, chlorine gas undergoes an electrophilic substitution reaction with the phenyl ring in 2-methyl-1-nitrobenzene. Due to the fact that nitro is an meta-locator and methyl is an ortho-para-locator, the two work together to make the chlorine atom mainly replace the ortho-site of methyl to obtain 4-chloro-2-methyl-1-nitrobenzene. The chemical equation of the reaction is roughly as follows: $C_7H_7NO_2 + Cl_2\ xrightarrow [] {Fe or FeCl_3} C_7H_6ClNO_2 + HCl $.
Another method, or 4-chloro-2-methylbenzene can be used as the raw material. Let it be nitrified with nitrate sources, such as mixed acids of concentrated nitric acid ($HNO_3 $) and concentrated sulfuric acid ($H_2SO_4 $). In the reaction of concentrated sulfuric acid, one is used as a dehydrating agent, and the other is to protonate nitric acid and enhance its electrophilic ability. During the reaction, the nitro positive ion attacks the benzene ring. Due to the positioning effect of the methyl group, the nitro group mainly enters the ortho-position of the methyl group, so 4-chloro-2-methyl-1-nitrobenzene is obtained. The chemical equation of the reaction is probably: $C_7H_7Cl + HNO_3\ xrightarrow [] {H_2SO_4} C_7H_6ClNO_2 + H_2O $. When preparing
, pay attention to the conditions of the reaction. The temperature depends on the rate of reaction and the selectivity of the product. In the chlorination reaction, the temperature is too high, which may cause the formation of polychlorinated substitutes; in the nitrification reaction, the temperature is inappropriate, or by-products are produced. And the solvent of the reaction also needs to be carefully selected, which affects the solubility and reaction mechanism of the reactants. At the end of the reaction, the product often needs to be separated and purified, such as distillation, recrystallization, column chromatography, etc., to obtain pure 4-chloro-2-methyl-1-nitrobenzene.
4-chloro-2-methyl-1-nitrobenzene what are the precautions during use
4-Chloro-2-methyl-1-nitrobenzene is also an organic compound. During use, many matters must be paid attention to.
The first priority is safety, and this compound is toxic and irritating. If it accidentally touches the skin, rinse with plenty of water as soon as possible, followed by soap; if it enters the eyes, rinse with plenty of water immediately, and seek medical attention as soon as possible. When using, it is advisable to wear protective clothing, gloves and goggles to avoid direct contact.
Furthermore, it is related to the environment. It may be harmful to the environment, so the use and disposal process must be cautious. The waste generated by the experiment should not be discarded at will. It should be collected and treated in accordance with relevant regulations to prevent contamination of soil, water sources, etc.
Repeat, related to storage. It needs to be stored in a cool and ventilated place, away from fire and heat sources. And it should be stored separately from oxidants, edible chemicals, etc., and should not be mixed with storage to avoid dangerous reactions.
In addition, when using, precisely control the dosage, and use it reasonably according to experimental or production needs to avoid waste. The operation process also needs to be rigorous, follow the established operating procedures, and do not omit to prevent accidents. In short, the use of this compound must be done with caution to ensure safety and environmental damage.
The first priority is safety, and this compound is toxic and irritating. If it accidentally touches the skin, rinse with plenty of water as soon as possible, followed by soap; if it enters the eyes, rinse with plenty of water immediately, and seek medical attention as soon as possible. When using, it is advisable to wear protective clothing, gloves and goggles to avoid direct contact.
Furthermore, it is related to the environment. It may be harmful to the environment, so the use and disposal process must be cautious. The waste generated by the experiment should not be discarded at will. It should be collected and treated in accordance with relevant regulations to prevent contamination of soil, water sources, etc.
Repeat, related to storage. It needs to be stored in a cool and ventilated place, away from fire and heat sources. And it should be stored separately from oxidants, edible chemicals, etc., and should not be mixed with storage to avoid dangerous reactions.
In addition, when using, precisely control the dosage, and use it reasonably according to experimental or production needs to avoid waste. The operation process also needs to be rigorous, follow the established operating procedures, and do not omit to prevent accidents. In short, the use of this compound must be done with caution to ensure safety and environmental damage.
Scan to WhatsApp
