Linshang Chemical
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4-Chloro-2-Nitrobenzenesulfonyl Chloride
Linshang Chemical
|
HS Code |
775668 |
| Name | 4-Chloro-2-Nitrobenzenesulfonyl Chloride |
| Molecular Formula | C6H3Cl2NO4S |
| Molecular Weight | 256.06 |
| Appearance | Yellow to brown solid |
| Melting Point | 64 - 68 °C |
| Boiling Point | Decomposes |
| Solubility | Soluble in organic solvents like dichloromethane |
| Density | Approx. 1.75 g/cm³ |
| Purity | Typically high purity in commercial products |
| Stability | Stable under normal conditions but reacts with water, bases |
As an accredited 4-Chloro-2-Nitrobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - chloro - 2 - nitrobenzenesulfonyl chloride packaged in a sealed, corrosion - resistant bottle. |
| Storage | 4 - chloro - 2 - nitrobenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It must be kept in a tightly sealed container to prevent moisture absorption and contact with air. Store it separately from incompatible substances like oxidizing agents, bases, and reducing agents to avoid dangerous reactions. |
| Shipping | 4 - chloro - 2 - nitrobenzenesulfonyl chloride is a chemical. Ship it in well - sealed, corrosion - resistant containers. Follow strict hazardous material shipping regulations, ensuring proper labeling and handling to prevent spills and ensure safety during transit. |
Competitive 4-Chloro-2-Nitrobenzenesulfonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Chloro-2-Nitrobenzenesulfonyl Chloride in China?
As a trusted 4-Chloro-2-Nitrobenzenesulfonyl Chloride manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Chloro-2-Nitrobenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4-chloro-2-nitrobenzenesulfonyl Chloride?
4-Chloro-2-nitrobenzenesulfonyl chloride is an important chemical raw material in organic synthesis. It has a wide range of uses, first in the field of pharmaceutical synthesis. In this field, it is often a key starting material for the preparation of specific drug intermediates. For example, it can be introduced into the molecular structure of drugs through a series of chemical transformations, giving drugs unique activities and characteristics, which is very helpful for the development of antibacterial, antiviral and other drugs.
In the synthesis of pesticides, 4-chloro-2-nitrobenzenesulfonyl chloride is also indispensable. Through clever reactions, it can prepare efficient pesticide ingredients, or have the functions of insecticides, weeds, and sterilization, which can help agricultural production to increase yield and resist pest attacks.
Furthermore, in the field of dye synthesis, this compound can be used as an important cornerstone for the construction of special structural dyes. Through fine chemical reactions, dye molecules with bright colors and excellent fastness are constructed, which are widely used in textile printing and dyeing and other industries to add colorful colors to fabrics.
In addition, in the field of materials science, it may participate in the synthesis of polymer materials with special properties. After appropriate reaction, the structural units are introduced into the polymer chain, which can endow the material with good thermal stability, chemical stability or special optical properties, etc., to meet the diverse needs of material properties in different fields. Overall, 4-chloro-2-nitrobenzenesulfonyl chloride plays a crucial role in many chemical and related industries, promoting the development and progress of technologies in various fields.
In the synthesis of pesticides, 4-chloro-2-nitrobenzenesulfonyl chloride is also indispensable. Through clever reactions, it can prepare efficient pesticide ingredients, or have the functions of insecticides, weeds, and sterilization, which can help agricultural production to increase yield and resist pest attacks.
Furthermore, in the field of dye synthesis, this compound can be used as an important cornerstone for the construction of special structural dyes. Through fine chemical reactions, dye molecules with bright colors and excellent fastness are constructed, which are widely used in textile printing and dyeing and other industries to add colorful colors to fabrics.
In addition, in the field of materials science, it may participate in the synthesis of polymer materials with special properties. After appropriate reaction, the structural units are introduced into the polymer chain, which can endow the material with good thermal stability, chemical stability or special optical properties, etc., to meet the diverse needs of material properties in different fields. Overall, 4-chloro-2-nitrobenzenesulfonyl chloride plays a crucial role in many chemical and related industries, promoting the development and progress of technologies in various fields.
What are the physical properties of 4-chloro-2-nitrobenzenesulfonyl Chloride?
4-Chloro-2-nitrobenzenesulfonyl chloride is an important compound in organic chemistry. Its physical properties are particularly critical and are related to many practical applications.
Looking at its morphology, under normal temperature and pressure, 4-chloro-2-nitrobenzenesulfonyl chloride often takes the shape of a white-like to light yellow crystalline powder. This morphology is easy to identify, and in laboratory or industrial production, its physical state can be preliminarily identified based on this characteristic.
As for the melting point, the melting point of this compound is about 40-44 ° C. Melting point is an inherent property of a substance. Accurate determination of melting point not only verifies its purity, but also is crucial for grasping its state transition under different temperature conditions. For example, in the heating process, when approaching the melting point, the temperature should be carefully adjusted to prevent premature melting and affect the subsequent reaction process.
Boiling point is also one of its important physical properties. Although the specific boiling point data will vary slightly due to the measurement conditions, it is roughly within a certain range. Knowing the boiling point, you can set the appropriate temperature during distillation, separation and other operations to achieve effective separation from other substances.
Furthermore, the solubility cannot be ignored. 4-Chloro-2-nitrobenzenesulfonyl chloride has a certain solubility in some organic solvents, such as common acetone, dichloromethane, etc. This solubility property provides a basis for the selection of reaction media in organic synthesis. The selection of suitable solvents can fully contact the reactants, accelerate the reaction, and improve the reaction efficiency and yield.
The physical properties of 4-chloro-2-nitrobenzenesulfonyl chloride play a pivotal role in organic synthesis, chemical production and other fields, laying a solid foundation for the smooth development of many operations and reactions.
Looking at its morphology, under normal temperature and pressure, 4-chloro-2-nitrobenzenesulfonyl chloride often takes the shape of a white-like to light yellow crystalline powder. This morphology is easy to identify, and in laboratory or industrial production, its physical state can be preliminarily identified based on this characteristic.
As for the melting point, the melting point of this compound is about 40-44 ° C. Melting point is an inherent property of a substance. Accurate determination of melting point not only verifies its purity, but also is crucial for grasping its state transition under different temperature conditions. For example, in the heating process, when approaching the melting point, the temperature should be carefully adjusted to prevent premature melting and affect the subsequent reaction process.
Boiling point is also one of its important physical properties. Although the specific boiling point data will vary slightly due to the measurement conditions, it is roughly within a certain range. Knowing the boiling point, you can set the appropriate temperature during distillation, separation and other operations to achieve effective separation from other substances.
Furthermore, the solubility cannot be ignored. 4-Chloro-2-nitrobenzenesulfonyl chloride has a certain solubility in some organic solvents, such as common acetone, dichloromethane, etc. This solubility property provides a basis for the selection of reaction media in organic synthesis. The selection of suitable solvents can fully contact the reactants, accelerate the reaction, and improve the reaction efficiency and yield.
The physical properties of 4-chloro-2-nitrobenzenesulfonyl chloride play a pivotal role in organic synthesis, chemical production and other fields, laying a solid foundation for the smooth development of many operations and reactions.
4-chloro-2-nitrobenzenesulfonyl the chemistry of Chloride
4-Chloro-2-nitrobenzenesulfonyl chloride, this material is strong and active, and is often a key agent in various chemical reactions.
It is highly corrosive and touches the skin and mucous membranes, causing immediate damage, such as being burned by fire. In the air, it is easy to absorb moisture and hydrolyze, and gradually changes, so it must be tightly sealed to avoid interaction with water vapor.
In terms of its chemical activity, sulfonyl chloride is very active, often involved in the reaction of nucleophilic substitution. It can react quickly with alcohols and amines to form esters and amides. And the chlorine atom and nitro group on the aromatic ring also affect the reaction direction. Nitro has strong electron-absorbing properties, causing the electron cloud density of aromatic rings to decrease, making the electrophilic substitution reaction difficult, while nucleophilic substitution is prone to occur. Chlorine atoms can be replaced by nucleophilic reagents under appropriate conditions, introducing different groups, which is a broad path for organic synthesis.
And because of the coexistence of multiple groups in its structure, under different reaction conditions, each group reacts in sequence or at the same time, resulting in complex and changeable reactions. Therefore, when using, it is necessary to carefully observe the reaction conditions, accurately control the temperature and speed, so that the reaction can be smooth and the expected product can be obtained, so as to avoid accidental side effects. During operation, protective equipment must be kept in a well-ventilated place to ensure safety.
It is highly corrosive and touches the skin and mucous membranes, causing immediate damage, such as being burned by fire. In the air, it is easy to absorb moisture and hydrolyze, and gradually changes, so it must be tightly sealed to avoid interaction with water vapor.
In terms of its chemical activity, sulfonyl chloride is very active, often involved in the reaction of nucleophilic substitution. It can react quickly with alcohols and amines to form esters and amides. And the chlorine atom and nitro group on the aromatic ring also affect the reaction direction. Nitro has strong electron-absorbing properties, causing the electron cloud density of aromatic rings to decrease, making the electrophilic substitution reaction difficult, while nucleophilic substitution is prone to occur. Chlorine atoms can be replaced by nucleophilic reagents under appropriate conditions, introducing different groups, which is a broad path for organic synthesis.
And because of the coexistence of multiple groups in its structure, under different reaction conditions, each group reacts in sequence or at the same time, resulting in complex and changeable reactions. Therefore, when using, it is necessary to carefully observe the reaction conditions, accurately control the temperature and speed, so that the reaction can be smooth and the expected product can be obtained, so as to avoid accidental side effects. During operation, protective equipment must be kept in a well-ventilated place to ensure safety.
What is the preparation method of 4-chloro-2-nitrobenzenesulfonyl Chloride?
The preparation method of 4-chloro-2-nitrobenzene sulfonyl chloride is an important topic in the field of organic synthesis. In the past, this compound was prepared by classical chemical synthesis.
One method is to use 4-chloro-2-nitrobenzene as the starting material. First, 4-chloro-2-nitrobenzene is co-heated with fuming sulfuric acid, and after a sulfonation reaction, 4-chloro-2-nitrobenzene sulfuric acid can be prepared. In this step of reaction, attention should be paid to the control of reaction temperature and time. If the temperature is too high or the time is too long, it is easy to cause side reactions to breed and affect the purity of the product.
After 4-chloro-2-nitrobenzenesulfonic acid is obtained, it is reacted with chlorination reagents such as phosphorus pentachloride or dichlorosulfoxide. Take phosphorus pentachloride as an example, the two are mixed in a suitable organic solvent, such as dichloromethane or chloroform, and heated to reflux. The chlorine atom in phosphorus pentachloride is highly active and can substitution and react with the hydroxyl group in the sulfonic acid group to eventually generate 4-chloro-2-nitrobenzenesulfonyl chloride. After the reaction is completed, the target product can be obtained through post-treatment steps such as distillation, extraction, and recrystallization.
There are those who use o-nit 4-Chloro-2-nitrobenzenesulfonyl chloride can also be obtained by sulfonation of o-nitrochlorobenzene first, followed by chlorination. This route also requires fine regulation of the reaction conditions at each step, such as the concentration and temperature of sulfuric acid during sulfonation, the amount of chlorination agent and the reaction environment during chlorination, etc., to improve the yield and purity of the product.
Preparation of 4-chloro-2-nitrobenzenesulfonyl chloride requires strict control of the reaction conditions at each step and fine operation to obtain high-quality products efficiently.
One method is to use 4-chloro-2-nitrobenzene as the starting material. First, 4-chloro-2-nitrobenzene is co-heated with fuming sulfuric acid, and after a sulfonation reaction, 4-chloro-2-nitrobenzene sulfuric acid can be prepared. In this step of reaction, attention should be paid to the control of reaction temperature and time. If the temperature is too high or the time is too long, it is easy to cause side reactions to breed and affect the purity of the product.
After 4-chloro-2-nitrobenzenesulfonic acid is obtained, it is reacted with chlorination reagents such as phosphorus pentachloride or dichlorosulfoxide. Take phosphorus pentachloride as an example, the two are mixed in a suitable organic solvent, such as dichloromethane or chloroform, and heated to reflux. The chlorine atom in phosphorus pentachloride is highly active and can substitution and react with the hydroxyl group in the sulfonic acid group to eventually generate 4-chloro-2-nitrobenzenesulfonyl chloride. After the reaction is completed, the target product can be obtained through post-treatment steps such as distillation, extraction, and recrystallization.
There are those who use o-nit 4-Chloro-2-nitrobenzenesulfonyl chloride can also be obtained by sulfonation of o-nitrochlorobenzene first, followed by chlorination. This route also requires fine regulation of the reaction conditions at each step, such as the concentration and temperature of sulfuric acid during sulfonation, the amount of chlorination agent and the reaction environment during chlorination, etc., to improve the yield and purity of the product.
Preparation of 4-chloro-2-nitrobenzenesulfonyl chloride requires strict control of the reaction conditions at each step and fine operation to obtain high-quality products efficiently.
What are the precautions for 4-chloro-2-nitrobenzenesulfonyl Chloride in storage and transportation?
4-Chloro-2-nitrobenzenesulfonyl chloride is a chemical substance. During storage and transportation, many matters cannot be ignored.
First words storage. This material is very active and easy to react with other things, so it should be placed in a cool, dry and well-ventilated place. Do not be near fire or heat to prevent it from changing due to high temperature or causing danger. And it must be stored separately from alkalis, alcohols, etc., because it is easy to neutralize with alkalis, and it may react differently with alcohols or alcohols to cause qualitative changes. The storage device should be corrosion-resistant, glass or specific plastic containers are preferred to prevent it from being damaged by the wall.
As for transportation, it must be carried out in accordance with relevant laws and regulations. Packaging must be tight to prevent leakage. When handling, the operator should be in front of suitable protective equipment, such as gloves, goggles, protective clothing, etc., to prevent it from touching the body and causing damage to the skin and eyes. During transportation, avoid shocks and collisions, and drive slowly to ensure its stability. If the transportation is in high temperatures, pay more attention to cooling, so as not to be disturbed by heat.
In short, the storage and transportation of 4-chloro-2-nitrobenzenesulfonyl chloride should be handled with caution. According to the law, it can be safe and avoid disasters.
First words storage. This material is very active and easy to react with other things, so it should be placed in a cool, dry and well-ventilated place. Do not be near fire or heat to prevent it from changing due to high temperature or causing danger. And it must be stored separately from alkalis, alcohols, etc., because it is easy to neutralize with alkalis, and it may react differently with alcohols or alcohols to cause qualitative changes. The storage device should be corrosion-resistant, glass or specific plastic containers are preferred to prevent it from being damaged by the wall.
As for transportation, it must be carried out in accordance with relevant laws and regulations. Packaging must be tight to prevent leakage. When handling, the operator should be in front of suitable protective equipment, such as gloves, goggles, protective clothing, etc., to prevent it from touching the body and causing damage to the skin and eyes. During transportation, avoid shocks and collisions, and drive slowly to ensure its stability. If the transportation is in high temperatures, pay more attention to cooling, so as not to be disturbed by heat.
In short, the storage and transportation of 4-chloro-2-nitrobenzenesulfonyl chloride should be handled with caution. According to the law, it can be safe and avoid disasters.
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