Linshang Chemical
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4-Chloro-3,5-Dinitrotrifluoromethylbenzene
Linshang Chemical
|
HS Code |
439778 |
| Chemical Formula | C7H2ClF3N2O4 |
| Molar Mass | 272.55 g/mol |
| Appearance | Yellow to orange - red solid |
| Melting Point | 55 - 57 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Vapor Pressure | Low vapor pressure |
As an accredited 4-Chloro-3,5-Dinitrotrifluoromethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - chloro - 3,5 - dinitrotrifluoromethylbenzene in sealed, chemical - resistant packaging. |
| Storage | 4 - chloro - 3,5 - dinitrotrifluoromethylbenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat, flames, and oxidizing agents. Store in a tightly - sealed container to prevent leakage. Due to its potential hazards, ensure storage is in a dedicated chemical storage area, separate from incompatible substances, following strict safety regulations. |
| Shipping | 4 - chloro - 3,5 - dinitrotrifluoromethylbenzene is a chemical. It should be shipped in accordance with hazardous materials regulations, using proper packaging to prevent leakage and ensure safe transport during transit. |
Competitive 4-Chloro-3,5-Dinitrotrifluoromethylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Chloro-3,5-Dinitrotrifluoromethylbenzene in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Chloro-3,5-Dinitrotrifluoromethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
4-Chloro-3, what are the chemical properties of 5-dinitrotrifluoromethylbenzene
4-Chloro-3,5-dinitrotrifluoromethylbenzene is one of the organic compounds. Its chemical properties are unique and valuable for investigation.
In this compound, the presence of chlorine atoms, nitro groups and trifluoromethyl groups endows it with various chemical properties. Chlorine atoms have certain nucleophilic substitution activities. Due to their electronegativity differences, they can change the electron cloud density of the benzene ring, and are easily replaced by nucleophilic reagents under suitable conditions.
Nitro is a strong electron-absorbing group, which not only enhances the electrophilic substitution activity of the benzene ring, but also makes it more likely to react with electrophilic reagents, and has a significant impact on the redox properties of the compound. Nitro groups can participate in the reduction reaction and transform into other functional groups such as amino groups, which is widely used in the field of organic synthesis. The introduction of trifluoromethyl groups
greatly changes the physical and chemical properties of molecules. Due to its strong electron absorption and hydrophobicity, it improves the stability and lipid solubility of compounds, and has a profound impact on their absorption, distribution, and metabolism in vivo.
Furthermore, the chemical properties of 4-chloro-3,5-dinitrotrifluoromethylbenzene are influenced by the conjugation system of benzene ring. The conjugation structure of benzene ring allows the intracellular electron cloud to be delocalized, stabilizes the molecular structure, and also affects the interaction of various functional groups, resulting in complex changes in chemical reaction activity and selectivity.
In conclusion, the chemical properties of 4-chloro-3,5-dinitrotrifluoromethylbenzene exhibit rich and diverse characteristics due to the interaction of functional groups and benzene ring conjugation system, and have important application potential in many fields such as organic synthesis, medicinal chemistry, and materials science.
In this compound, the presence of chlorine atoms, nitro groups and trifluoromethyl groups endows it with various chemical properties. Chlorine atoms have certain nucleophilic substitution activities. Due to their electronegativity differences, they can change the electron cloud density of the benzene ring, and are easily replaced by nucleophilic reagents under suitable conditions.
Nitro is a strong electron-absorbing group, which not only enhances the electrophilic substitution activity of the benzene ring, but also makes it more likely to react with electrophilic reagents, and has a significant impact on the redox properties of the compound. Nitro groups can participate in the reduction reaction and transform into other functional groups such as amino groups, which is widely used in the field of organic synthesis. The introduction of trifluoromethyl groups
greatly changes the physical and chemical properties of molecules. Due to its strong electron absorption and hydrophobicity, it improves the stability and lipid solubility of compounds, and has a profound impact on their absorption, distribution, and metabolism in vivo.
Furthermore, the chemical properties of 4-chloro-3,5-dinitrotrifluoromethylbenzene are influenced by the conjugation system of benzene ring. The conjugation structure of benzene ring allows the intracellular electron cloud to be delocalized, stabilizes the molecular structure, and also affects the interaction of various functional groups, resulting in complex changes in chemical reaction activity and selectivity.
In conclusion, the chemical properties of 4-chloro-3,5-dinitrotrifluoromethylbenzene exhibit rich and diverse characteristics due to the interaction of functional groups and benzene ring conjugation system, and have important application potential in many fields such as organic synthesis, medicinal chemistry, and materials science.
What are the main uses of 4-chloro-3, 5-dinitrotrifluoromethylbenzene
4-Chloro-3,5-dinitrotrifluoromethylbenzene has a wide range of uses. In the field of medicine, it is often used as a key intermediate. The chlorine atoms, nitro groups and trifluoromethyl groups attached to the benzene ring give it unique chemical activity. It can introduce other functional groups through various chemical reactions, and then build complex drug molecules. For example, in the synthesis process of some antibacterial and anti-inflammatory drugs, this material can be used as a starting material to effectively synthesize target drugs through nucleophilic substitution, reduction and other reaction steps, making great contributions to human health.
In the field of pesticides, it also plays an important role. Due to its special structure, compounds with high insecticidal, bactericidal or herbicidal activities can be derived. By adjusting the type, position and quantity of substituents on the benzene ring, its biological activity and selectivity can be precisely regulated to meet the needs of different crops and control objects, which is of great significance for ensuring agricultural harvests and reducing the ravages of pests and diseases.
Furthermore, in the field of materials science, this compound can be used to prepare special functional materials. Because it contains strong electron-absorbing nitro groups and trifluoromethyl groups, it can make the material have unique electrical, optical or thermal properties. For example, it can be used to make high-performance liquid crystal materials, which can optimize the arrangement and phase transition temperature of liquid crystal molecules and improve the display effect; it can also be used to synthesize organic semiconductor materials with special electrical conductivity, contributing to the development of electronic devices.
In addition, in the study of organic synthesis chemistry, 4-chloro-3,5-dinitrotrifluoromethylbenzene is often used as a model compound. With the help of in-depth exploration of its chemical reaction mechanism, researchers can provide theoretical basis and practical experience for the development of new organic synthesis methods, promote the continuous development of organic synthesis chemistry, and expand the cognitive boundaries of human beings on the construction and transformation of organic compounds.
In the field of pesticides, it also plays an important role. Due to its special structure, compounds with high insecticidal, bactericidal or herbicidal activities can be derived. By adjusting the type, position and quantity of substituents on the benzene ring, its biological activity and selectivity can be precisely regulated to meet the needs of different crops and control objects, which is of great significance for ensuring agricultural harvests and reducing the ravages of pests and diseases.
Furthermore, in the field of materials science, this compound can be used to prepare special functional materials. Because it contains strong electron-absorbing nitro groups and trifluoromethyl groups, it can make the material have unique electrical, optical or thermal properties. For example, it can be used to make high-performance liquid crystal materials, which can optimize the arrangement and phase transition temperature of liquid crystal molecules and improve the display effect; it can also be used to synthesize organic semiconductor materials with special electrical conductivity, contributing to the development of electronic devices.
In addition, in the study of organic synthesis chemistry, 4-chloro-3,5-dinitrotrifluoromethylbenzene is often used as a model compound. With the help of in-depth exploration of its chemical reaction mechanism, researchers can provide theoretical basis and practical experience for the development of new organic synthesis methods, promote the continuous development of organic synthesis chemistry, and expand the cognitive boundaries of human beings on the construction and transformation of organic compounds.
What is the preparation method of 4-chloro-3, 5-dinitrotrifluoromethylbenzene
The preparation method of 4-chloro-3,5-dinitrotrifluoromethylbenzene is an important topic in the field of chemical synthesis. There are several common methods for its preparation.
First, trifluoromethylbenzene can be started. First, chlorination is used to introduce chlorine atoms into the benzene ring. Usually chlorine is used as a chlorination agent, and under the catalysis of suitable catalysts such as iron or its salts, trifluoromethylbenzene is reacted with chlorine to obtain chlorotrifluoromethylbenzene. This reaction should be paid attention to the reaction temperature and the rate of chlorine gas introduction to prevent excessive chlorination.
Then, chlorotrifluoromethylbenzene is nitrified. The mixture of concentrated nitric acid and concentrated sulfuric acid is used as the nitrifying reagent, and the ratio of the two, reaction temperature and reaction time are all key factors. Under suitable conditions, nitrate ions attack the benzene ring as an electrophilic reagent, preferentially substituting at the ortho and para positions of chlorine atoms. After precise regulation, nitro groups can be mainly introduced into the 3,5 positions to prepare 4-chloro-3,5-dinitrotrifluoromethylbenzene.
Second, it can also be prepared from other suitable raw materials by multi-step reaction. For example, a specific halogenated aromatic hydrocarbon is used as the starting material, and a trifluoromethyl group is first introduced. In this step, metal-organic reagents can be used to couple with halogenated aromatic hydrocarbons. Then chlorination and nitrification are carried out in sequence, and the purpose of preparing the target product can be achieved by optimizing the reaction conditions of each step. During the preparation process, the products of each step need to be separated and purified. Common methods include distillation, recrystallization, column chromatography, etc., to ensure the purity and yield of the final product.
First, trifluoromethylbenzene can be started. First, chlorination is used to introduce chlorine atoms into the benzene ring. Usually chlorine is used as a chlorination agent, and under the catalysis of suitable catalysts such as iron or its salts, trifluoromethylbenzene is reacted with chlorine to obtain chlorotrifluoromethylbenzene. This reaction should be paid attention to the reaction temperature and the rate of chlorine gas introduction to prevent excessive chlorination.
Then, chlorotrifluoromethylbenzene is nitrified. The mixture of concentrated nitric acid and concentrated sulfuric acid is used as the nitrifying reagent, and the ratio of the two, reaction temperature and reaction time are all key factors. Under suitable conditions, nitrate ions attack the benzene ring as an electrophilic reagent, preferentially substituting at the ortho and para positions of chlorine atoms. After precise regulation, nitro groups can be mainly introduced into the 3,5 positions to prepare 4-chloro-3,5-dinitrotrifluoromethylbenzene.
Second, it can also be prepared from other suitable raw materials by multi-step reaction. For example, a specific halogenated aromatic hydrocarbon is used as the starting material, and a trifluoromethyl group is first introduced. In this step, metal-organic reagents can be used to couple with halogenated aromatic hydrocarbons. Then chlorination and nitrification are carried out in sequence, and the purpose of preparing the target product can be achieved by optimizing the reaction conditions of each step. During the preparation process, the products of each step need to be separated and purified. Common methods include distillation, recrystallization, column chromatography, etc., to ensure the purity and yield of the final product.
What are the precautions for 4-chloro-3, 5-dinitrotrifluoromethylbenzene during storage and transportation?
4-Chloro-3,5-dinitrotrifluoromethylbenzene is also an organic compound. When storing and transporting it, many matters need to be paid attention to.
When storing, the first choice of environment. It should be placed in a cool, dry and well-ventilated place. This is dangerous because of its lively nature, high temperature, humid environment, or deterioration. For example, in hot summer and heat, if it exists in a warm place, it may cause chemical reactions, causing it to decompose or explode. And it needs to be kept away from fire and heat sources. Because of its flammability and explosive nature, it is easy to cause accidents in case of open flames and hot topics, such as firecrackers exploding in case of fire.
Furthermore, it should be stored separately from oxidants and alkalis. This is due to its chemical properties. When mixed with oxidants, it is easy to cause oxidation reactions; when coexisted with alkalis, neutralization and other reactions may occur, which will endanger safety, just like water and fire are incompatible.
Storage containers also need to be carefully selected. Corrosion-resistant materials must be used. The cover is corrosive because it contains chlorine, nitro, trifluoromethyl and other groups, which can erode containers made of ordinary materials. If the container is damaged and the material leaks, it will be extremely harmful. If the dam breaks, the flood will come.
When transporting, make sure that the container is well sealed and stable without shaking. Protect from sun exposure, rain, and high temperature on the way. If the vehicle is on the road, if it is exposed to the hot sun, or initialized in a rainstorm, or is in a high temperature area, it may damage the material and cause danger.
Transportation personnel should also be familiar with the characteristics of this object and emergency treatment methods. In case of leakage and other situations, it can be disposed of in time to avoid major disasters. If there is a leak, quickly isolate the scene, evacuate the crowd, and clean up according to the standard process. Do not spread the hazard. Just like a fire, quickly fight it to prevent it from starting a prairie fire.
In short, when storing and transporting 4-chloro-3,5-dinitrotrifluoromethylbenzene, many details are related to safety and must be treated with caution and not sloppy at all.
When storing, the first choice of environment. It should be placed in a cool, dry and well-ventilated place. This is dangerous because of its lively nature, high temperature, humid environment, or deterioration. For example, in hot summer and heat, if it exists in a warm place, it may cause chemical reactions, causing it to decompose or explode. And it needs to be kept away from fire and heat sources. Because of its flammability and explosive nature, it is easy to cause accidents in case of open flames and hot topics, such as firecrackers exploding in case of fire.
Furthermore, it should be stored separately from oxidants and alkalis. This is due to its chemical properties. When mixed with oxidants, it is easy to cause oxidation reactions; when coexisted with alkalis, neutralization and other reactions may occur, which will endanger safety, just like water and fire are incompatible.
Storage containers also need to be carefully selected. Corrosion-resistant materials must be used. The cover is corrosive because it contains chlorine, nitro, trifluoromethyl and other groups, which can erode containers made of ordinary materials. If the container is damaged and the material leaks, it will be extremely harmful. If the dam breaks, the flood will come.
When transporting, make sure that the container is well sealed and stable without shaking. Protect from sun exposure, rain, and high temperature on the way. If the vehicle is on the road, if it is exposed to the hot sun, or initialized in a rainstorm, or is in a high temperature area, it may damage the material and cause danger.
Transportation personnel should also be familiar with the characteristics of this object and emergency treatment methods. In case of leakage and other situations, it can be disposed of in time to avoid major disasters. If there is a leak, quickly isolate the scene, evacuate the crowd, and clean up according to the standard process. Do not spread the hazard. Just like a fire, quickly fight it to prevent it from starting a prairie fire.
In short, when storing and transporting 4-chloro-3,5-dinitrotrifluoromethylbenzene, many details are related to safety and must be treated with caution and not sloppy at all.
What are the effects of 4-chloro-3, 5-dinitrotrifluoromethylbenzene on the environment and human body?
4-Chloro-3,5-dinitrotrifluoromethylbenzene is also an organic compound. It has an impact on the environment and human body.
Discussing the impact on the environment, if this compound is released in nature, it may be difficult to degrade. Its chlorine, fluorine and nitro groups, in the soil, or cause gradual changes in soil properties, prevent plant roots from ingesting nutrients, and then affect plant growth. In water bodies, or with water flow migration, causing water pollution and endangering aquatic organisms. Because of toxicity, or causing physiological dysfunction of aquatic organisms, population loss, destroying the balance of aquatic ecology.
As for the effects on the human body, if people ingest this compound through breathing, skin contact or diet, it is quite harmful. It may irritate the respiratory tract, cause cough, asthma, breathing difficulties and other diseases, long-term exposure, and even cause lung diseases. Contact with the skin can cause skin redness, swelling, itching, burning, and damage the skin barrier function. If ingested inadvertently, it may cause digestive system disorders, nausea, vomiting, abdominal pain, diarrhea, etc., and this compound may be potentially carcinogenic, teratogenic, and mutagenic. Long-term exposure will increase the risk of cancer in the human body, affect genetic material, and endanger the health of future generations.
In conclusion, 4-chloro-3,5-dinitrotrifluoromethylbenzene poses many potential hazards to the environment and the human body. When manufacturing, using, and handling, care should be taken to prevent it from causing adverse effects on the environment and the human body.
Discussing the impact on the environment, if this compound is released in nature, it may be difficult to degrade. Its chlorine, fluorine and nitro groups, in the soil, or cause gradual changes in soil properties, prevent plant roots from ingesting nutrients, and then affect plant growth. In water bodies, or with water flow migration, causing water pollution and endangering aquatic organisms. Because of toxicity, or causing physiological dysfunction of aquatic organisms, population loss, destroying the balance of aquatic ecology.
As for the effects on the human body, if people ingest this compound through breathing, skin contact or diet, it is quite harmful. It may irritate the respiratory tract, cause cough, asthma, breathing difficulties and other diseases, long-term exposure, and even cause lung diseases. Contact with the skin can cause skin redness, swelling, itching, burning, and damage the skin barrier function. If ingested inadvertently, it may cause digestive system disorders, nausea, vomiting, abdominal pain, diarrhea, etc., and this compound may be potentially carcinogenic, teratogenic, and mutagenic. Long-term exposure will increase the risk of cancer in the human body, affect genetic material, and endanger the health of future generations.
In conclusion, 4-chloro-3,5-dinitrotrifluoromethylbenzene poses many potential hazards to the environment and the human body. When manufacturing, using, and handling, care should be taken to prevent it from causing adverse effects on the environment and the human body.
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