Linshang Chemical
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4-Chloro-3-Nitro-N,N-Dimethylbenzenesulfonamide
Linshang Chemical
|
HS Code |
888388 |
| Chemical Formula | C8H9ClN2O4S |
| Molecular Weight | 264.69 |
| Appearance | Solid (usually a powder) |
| Physical State At Room Temp | Solid |
| Odor | Typically odorless or faint odor |
| Melting Point | Varies, specific data needed from literature |
| Boiling Point | Varies, specific data needed from literature |
| Solubility In Water | Low solubility |
| Solubility In Organic Solvents | Soluble in some organic solvents like dichloromethane |
| Density | Specific density data needed from literature |
| Stability | Stable under normal conditions but may react with strong oxidizing agents |
| Hazard Class | Potentially harmful if swallowed, inhaled or in contact with skin, classified as a hazardous chemical |
As an accredited 4-Chloro-3-Nitro-N,N-Dimethylbenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - chloro - 3 - nitro - N,N - dimethylbenzenesulfonamide in sealed chemical - grade bags. |
| Storage | 4 - chloro - 3 - nitro - N,N - dimethylbenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and potential reactions. Label the storage container clearly to avoid misidentification. |
| Shipping | 4 - chloro - 3 - nitro - N,N - dimethylbenzenesulfonamide is shipped in sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling and safe transportation to prevent spills and environmental risks. |
Competitive 4-Chloro-3-Nitro-N,N-Dimethylbenzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
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Tel: +8615365006308
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As a leading 4-Chloro-3-Nitro-N,N-Dimethylbenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide
4-Chloro-3-nitro-N, N-dimethylbenzenesulfonamide, this is an organic compound. Its physical properties, at room temperature or as a solid, have a specific melting point, boiling point, insoluble or slightly soluble in water, but soluble in organic solvents such as ethanol, ether, etc.
Looking at its chemical properties, the chlorine atom above the benzene ring has a significant impact on the nitro group. The chlorine atom is an electron-withdrawing group, which can reduce the electron cloud density of the benzene ring and reduce the electrophilic substitution reaction activity; the nitro group is a strong electron-withdrawing group, which can further reduce the electron cloud density of the benzene ring, making it more difficult for the benzene ring to undergo electrophilic substitution reaction. At the same time, the presence of the The sulfonamide group in the
molecule is quite active, and the lone pair of electrons on the nitrogen atom can participate in the reaction. When it encounters acid, it can bind to protons, causing its properties to change; when it encounters alkali, or hydrolysis occurs, the sulfonamide bond breaks, and the corresponding sulfonic acid and amine are formed.
In addition, the compound can undergo oxidation-reduction reactions under certain conditions because it contains elements such as chlorine, nitrogen, and sulfur. Chlorine atoms, nitro groups, and sulfonamide groups can all participate in such reactions, or be oxidized or reduced, depending on the reaction conditions and the reagents used.
It is rich in chemical properties and may be an important intermediate in the field of organic synthesis. It can be used to prepare organic compounds with more complex structures through various reactions. However, due to the presence of nitro and chlorine atoms, attention should be paid to its reactivity and safety during operation.
Looking at its chemical properties, the chlorine atom above the benzene ring has a significant impact on the nitro group. The chlorine atom is an electron-withdrawing group, which can reduce the electron cloud density of the benzene ring and reduce the electrophilic substitution reaction activity; the nitro group is a strong electron-withdrawing group, which can further reduce the electron cloud density of the benzene ring, making it more difficult for the benzene ring to undergo electrophilic substitution reaction. At the same time, the presence of the The sulfonamide group in the
molecule is quite active, and the lone pair of electrons on the nitrogen atom can participate in the reaction. When it encounters acid, it can bind to protons, causing its properties to change; when it encounters alkali, or hydrolysis occurs, the sulfonamide bond breaks, and the corresponding sulfonic acid and amine are formed.
In addition, the compound can undergo oxidation-reduction reactions under certain conditions because it contains elements such as chlorine, nitrogen, and sulfur. Chlorine atoms, nitro groups, and sulfonamide groups can all participate in such reactions, or be oxidized or reduced, depending on the reaction conditions and the reagents used.
It is rich in chemical properties and may be an important intermediate in the field of organic synthesis. It can be used to prepare organic compounds with more complex structures through various reactions. However, due to the presence of nitro and chlorine atoms, attention should be paid to its reactivity and safety during operation.
What are the main uses of 4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide
4-Chloro-3-nitro-N, N-dimethylbenzenesulfonamide, this is an organic compound. It has a wide range of uses and is used in many fields.
In the field of medicine, it may be used as an intermediate in drug synthesis. As the old saying goes, this compound is like the "cornerstone" of pharmaceutical synthesis. The creation of many drugs relies on it as a starting material and goes through a series of delicate chemical reactions to obtain medicines. For example, for some drugs with specific therapeutic effects, 4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide may be a key step in the synthesis path. After modification and transformation, it can endow the drug with precise pharmacological activity to treat diseases and remove diseases.
In the field of pesticides, it also has important uses. It can be used as a key component in the creation of pesticides, just like adding wings to the "guard" of crops. After rational design and synthesis, the pesticides made based on this compound may have efficient insecticidal, bactericidal or herbicidal properties, which can effectively protect crops from pests and weeds, and ensure the harvest of grain and the hard work of farmers.
In the field of materials science, its use should not be underestimated. Or contribute to the synthesis of new materials, such as participating in the preparation of special polymer materials. In this process, its unique chemical structure can endow materials with special properties, such as enhancing the stability of materials, improving their electrical or optical properties, etc., which is like adding bricks to the improvement of material properties and assisting the development of materials science to meet the needs of different fields for special performance materials.
In the field of medicine, it may be used as an intermediate in drug synthesis. As the old saying goes, this compound is like the "cornerstone" of pharmaceutical synthesis. The creation of many drugs relies on it as a starting material and goes through a series of delicate chemical reactions to obtain medicines. For example, for some drugs with specific therapeutic effects, 4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide may be a key step in the synthesis path. After modification and transformation, it can endow the drug with precise pharmacological activity to treat diseases and remove diseases.
In the field of pesticides, it also has important uses. It can be used as a key component in the creation of pesticides, just like adding wings to the "guard" of crops. After rational design and synthesis, the pesticides made based on this compound may have efficient insecticidal, bactericidal or herbicidal properties, which can effectively protect crops from pests and weeds, and ensure the harvest of grain and the hard work of farmers.
In the field of materials science, its use should not be underestimated. Or contribute to the synthesis of new materials, such as participating in the preparation of special polymer materials. In this process, its unique chemical structure can endow materials with special properties, such as enhancing the stability of materials, improving their electrical or optical properties, etc., which is like adding bricks to the improvement of material properties and assisting the development of materials science to meet the needs of different fields for special performance materials.
What is the synthesis method of 4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide
The synthesis of 4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide is quite complicated and requires careful steps.
The first benzenesulfonyl chloride is taken as the starting material, and it is slowly reacted with dimethylamine in a suitable solvent, such as dichloromethane and other inert solvents. This reaction needs to be carried out in a low temperature environment, about 0 to 5 degrees Celsius, and the temperature is carefully controlled. Due to the high activity of dimethylamine, slightly higher temperatures can easily cause a cluster of side reactions. During the reaction, dimethylamine is added dropwise to the solution of benzenesulfonyl chloride, and stirred evenly at the same time, so that the reaction can be carried out When the two are fully reacted, N, N-dimethylbenzenesulfonamide can be obtained.
Then N, N-dimethylbenzenesulfonamide is nitrified. The compound is dissolved into the mixed acid system of concentrated sulfuric acid and concentrated nitric acid. The mixed acid ratio needs to be precisely prepared. Generally, the volume ratio of concentrated sulfuric acid to concentrated nitric acid is about 3:1. The reaction temperature also needs to be strictly controlled, first at low temperature, about 5 to 10 degrees Celsius, for a period of time, so that the nitro group is initially introduced into the benzene ring, and then gradually heated to room temperature, and the reaction continues until the reaction is complete. In this process, the nitro group is preferentially substituted over the specific position of the benzene ring, that is, the 3-position, resulting in 3-nitro-N, N-dimethylbenzenesulfonamide.
Finally, 3-nitro-N, N-dimethylbenzenesulfonamide is chlorinated. Chlorine gas is used as a chlorination agent and reacts in an organic solvent such as carbon tetrachloride in the presence of a suitable catalyst such as iron powder or ferric chloride. The reaction temperature is controlled in a moderate range, about 50 to 60 degrees Celsius, chlorine gas slowly enters the reaction system, and chlorine atoms replace hydrogen atoms at a specific position on the benzene ring, that is, 4-position, and finally obtain 4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide. After each step of the reaction, it needs to go through separation and purification steps, such as extraction, distillation, recrystallization, etc., to obtain high-purity products to ensure the success of the overall synthesis.
The first benzenesulfonyl chloride is taken as the starting material, and it is slowly reacted with dimethylamine in a suitable solvent, such as dichloromethane and other inert solvents. This reaction needs to be carried out in a low temperature environment, about 0 to 5 degrees Celsius, and the temperature is carefully controlled. Due to the high activity of dimethylamine, slightly higher temperatures can easily cause a cluster of side reactions. During the reaction, dimethylamine is added dropwise to the solution of benzenesulfonyl chloride, and stirred evenly at the same time, so that the reaction can be carried out When the two are fully reacted, N, N-dimethylbenzenesulfonamide can be obtained.
Then N, N-dimethylbenzenesulfonamide is nitrified. The compound is dissolved into the mixed acid system of concentrated sulfuric acid and concentrated nitric acid. The mixed acid ratio needs to be precisely prepared. Generally, the volume ratio of concentrated sulfuric acid to concentrated nitric acid is about 3:1. The reaction temperature also needs to be strictly controlled, first at low temperature, about 5 to 10 degrees Celsius, for a period of time, so that the nitro group is initially introduced into the benzene ring, and then gradually heated to room temperature, and the reaction continues until the reaction is complete. In this process, the nitro group is preferentially substituted over the specific position of the benzene ring, that is, the 3-position, resulting in 3-nitro-N, N-dimethylbenzenesulfonamide.
Finally, 3-nitro-N, N-dimethylbenzenesulfonamide is chlorinated. Chlorine gas is used as a chlorination agent and reacts in an organic solvent such as carbon tetrachloride in the presence of a suitable catalyst such as iron powder or ferric chloride. The reaction temperature is controlled in a moderate range, about 50 to 60 degrees Celsius, chlorine gas slowly enters the reaction system, and chlorine atoms replace hydrogen atoms at a specific position on the benzene ring, that is, 4-position, and finally obtain 4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide. After each step of the reaction, it needs to go through separation and purification steps, such as extraction, distillation, recrystallization, etc., to obtain high-purity products to ensure the success of the overall synthesis.
4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide What are the precautions in storage and transportation?
4-Chloro-3-nitro-N, N-dimethylbenzenesulfonamide is a chemical substance, and many points need to be paid attention to during storage and transportation.
Bear the brunt, when storing, must choose a cool, dry and well-ventilated place. Because it may be more sensitive to heat, high temperature can easily cause chemical changes, and even cause dangerous reactions, so it is necessary to keep away from fire and heat sources to prevent accidents. In addition, this substance may be corrosive to a certain extent, and it must be stored separately from corrosive materials, and the storage container used should have good corrosion resistance, such as glass bottles or plastic bottles of specific materials, to prevent the container from being corroded and causing material leakage.
During transportation, the packaging must be sturdy and reliable to ensure that it will not be damaged during handling. Transport personnel should also be professionally trained to be familiar with the characteristics of the substance and emergency treatment methods. During transportation, pay close attention to changes in temperature and humidity to avoid exposure to bad weather or extreme environments. If there is a leak during transportation, do not panic, and deal with it immediately according to the established emergency plan. Evacuate surrounding personnel to prevent the spread of pollution.
In summary, the storage and transportation of 4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide must be strictly in accordance with relevant norms and requirements, and must not be taken lightly to ensure the safety of personnel and the environment.
Bear the brunt, when storing, must choose a cool, dry and well-ventilated place. Because it may be more sensitive to heat, high temperature can easily cause chemical changes, and even cause dangerous reactions, so it is necessary to keep away from fire and heat sources to prevent accidents. In addition, this substance may be corrosive to a certain extent, and it must be stored separately from corrosive materials, and the storage container used should have good corrosion resistance, such as glass bottles or plastic bottles of specific materials, to prevent the container from being corroded and causing material leakage.
During transportation, the packaging must be sturdy and reliable to ensure that it will not be damaged during handling. Transport personnel should also be professionally trained to be familiar with the characteristics of the substance and emergency treatment methods. During transportation, pay close attention to changes in temperature and humidity to avoid exposure to bad weather or extreme environments. If there is a leak during transportation, do not panic, and deal with it immediately according to the established emergency plan. Evacuate surrounding personnel to prevent the spread of pollution.
In summary, the storage and transportation of 4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide must be strictly in accordance with relevant norms and requirements, and must not be taken lightly to ensure the safety of personnel and the environment.
What are the effects of 4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide on the environment and human body?
4-Chloro-3-nitro-N, N-dimethylbenzenesulfonamide is also an organic compound. Its impact on the environment and human body is of great concern to the world.
At the environmental end, if this substance is released into nature, it may have many effects. Its chemical properties are relatively stable, and it may be difficult to degrade in soil and water bodies, resulting in long-term residues. In soil, it may interfere with the normal metabolism and ecological balance of soil microorganisms, which in turn affects the absorption of nutrients by plant roots and hinders plant growth. In water bodies, it may cause water quality to deteriorate, posing a threat to aquatic organisms. Because of its bioaccumulation, it is transmitted and enriched through the food chain layer by layer, and ultimately endangers the organisms at the high end of the food chain.
As for the personal impact, it should not be underestimated. It can enter the human body through respiratory inhalation, skin contact or accidental ingestion. After entering the human body, it may interfere with the normal physiological functions of the human body. Or damage the important organs of the human body such as the liver and kidneys, because it contains chlorine, nitro and other groups or is toxic, affecting the metabolism and detoxification functions of the organs. And this substance may be allergenic, and some people may experience allergic symptoms such as redness, swelling and itching after contact with it. Long-term exposure may even increase the risk of cancer, because nitro compounds may be potential carcinogens. Therefore, the production, use and discharge of 4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide should be carefully controlled to reduce its harm to the environment and people.
At the environmental end, if this substance is released into nature, it may have many effects. Its chemical properties are relatively stable, and it may be difficult to degrade in soil and water bodies, resulting in long-term residues. In soil, it may interfere with the normal metabolism and ecological balance of soil microorganisms, which in turn affects the absorption of nutrients by plant roots and hinders plant growth. In water bodies, it may cause water quality to deteriorate, posing a threat to aquatic organisms. Because of its bioaccumulation, it is transmitted and enriched through the food chain layer by layer, and ultimately endangers the organisms at the high end of the food chain.
As for the personal impact, it should not be underestimated. It can enter the human body through respiratory inhalation, skin contact or accidental ingestion. After entering the human body, it may interfere with the normal physiological functions of the human body. Or damage the important organs of the human body such as the liver and kidneys, because it contains chlorine, nitro and other groups or is toxic, affecting the metabolism and detoxification functions of the organs. And this substance may be allergenic, and some people may experience allergic symptoms such as redness, swelling and itching after contact with it. Long-term exposure may even increase the risk of cancer, because nitro compounds may be potential carcinogens. Therefore, the production, use and discharge of 4-chloro-3-nitro-N, N-dimethylbenzenesulfonamide should be carefully controlled to reduce its harm to the environment and people.
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