4-Chloro-3-Nitro-N-Phenylbenzenesulfonamide

Linshang Chemical

Specifications

HS Code

165953

Chemical Formula C12H9ClN2O4S
Molar Mass 312.73 g/mol
Appearance Solid (usually a powder or crystalline solid)
Color Typically pale - colored (varies but often off - white to light yellow)
Melting Point Data needed (check literature for accurate value)
Boiling Point Data needed (check literature for accurate value)
Solubility In Water Low solubility in water, due to its non - polar aromatic nature
Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, chloroform
Density Data needed (check literature for accurate value)
Pka Data needed (check literature for accurate value)
Flash Point Data needed (check literature for accurate value)
Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

As an accredited 4-Chloro-3-Nitro-N-Phenylbenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - chloro - 3 - nitro - N - phenylbenzenesulfonamide in a sealed, labeled container.
Storage 4 - chloro - 3 - nitro - N - phenylbenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container to prevent moisture absorption and contamination. It is advisable to store it separately from incompatible substances to avoid potential chemical reactions.
Shipping 4 - chloro - 3 - nitro - N - phenylbenzenesulfonamide should be shipped in accordance with hazardous chemical regulations. Use well - sealed containers, label clearly, and ensure proper handling to prevent spills and exposure during transit.
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4-Chloro-3-Nitro-N-Phenylbenzenesulfonamide 4-Chloro-3-Nitro-N-Phenylbenzenesulfonamide
General Information
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Frequently Asked Questions

As a leading 4-Chloro-3-Nitro-N-Phenylbenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of 4-chloro-3-nitro-N-phenylbenzenesulfonamide?
4-Chloro-3-nitro-N-phenylbenzenesulfonamide is an organic compound with an elegant chemical structure.
Looking at its structure, benzenesulfonamide is the basic structure. Among benzenesulfonamides, the sulfonyl group (-SO 2O NH-) is connected to the benzene ring. At a specific position in the benzene ring, the chlorine atom (-Cl) is connected at position 4, and the nitro group (-NO 2O) is introduced at position 3. Furthermore, the nitrogen atom (N) in the sulfonamide group is connected to another phenyl group.
The benzene ring, as a very common structural unit in organic chemistry, has a unique electron cloud distribution and chemical activity. Chlorine atoms, due to their electronegativity, can affect the electron cloud density of the benzene ring, changing the reactivity and localization effect of the benzene ring. Nitro, also a strong electron-absorbing group, can not only affect the electron cloud of the benzene ring, but also change the polarity of the whole molecule. The existence of N-phenyl further enriches the spatial structure and electronic properties of the molecule.
In this way, the chemical structure of 4-chloro-3-nitro-N-phenylbenzenesulfonamide is composed of benzene ring, chlorine atom, nitro group, sulfonylamino group and N-phenyl group. The interaction of each part endows the compound with specific physical and chemical properties, which may have unique applications in many fields such as organic synthesis and medicinal chemistry.
What are the main uses of 4-chloro-3-nitro-N-phenylbenzenesulfonamide?
4-Chloro-3-nitro-N-phenylbenzenesulfonamide is widely used. In the field of medicine, it is often used as a key intermediate in drug synthesis. The creation of many antibacterial and anti-inflammatory drugs relies on it as a starting material, which is converted into compounds with specific pharmacological activities through a series of delicate chemical reactions. Its structural characteristics give it the ability to participate in the construction of complex drug molecular structures, providing the possibility for the development of new and efficient drugs.
In pesticides, it also plays an important role. It can be used as an important component in the synthesis of pesticides to help prepare pesticide products with excellent insecticidal and bactericidal properties. Precise chemical design allows pesticides to exhibit high selectivity and strong lethality against specific pests and diseases, while reducing the adverse effects on the environment and non-target organisms, and escorting high agricultural yields.
Furthermore, in the field of materials science, 4-chloro-3-nitro-N-phenylbenzenesulfonamide can be used to develop materials with special properties. For example, through special processing, polymer materials with unique electrical, optical or thermal properties can be prepared, which can be used in electronic devices, optical instruments and other fields to promote technological innovation and development in related fields.
In summary, 4-chloro-3-nitro-N-phenylbenzenesulfonamide has important uses in many fields such as medicine, pesticides and materials science, and is of great significance to the progress and development of various fields.
What is 4-chloro-3-nitro-N-phenylbenzenesulfonamide synthesis method?
The synthesis of 4-chloro-3-nitro-N-phenylbenzenesulfonamide is a key research in the field of organic synthesis. This synthesis method can be achieved through multiple delicate reactions.
At the beginning, benzenesulfonyl chloride is often used as the base. The schilling benzenesulfonyl chloride meets aniline, and the two interact according to the principle of nucleophilic substitution. In a suitable reaction environment, such as a suitable temperature and the help of alkali catalysts, the chlorine atom in benzenesulfonyl chloride is replaced by the amino group of aniline, so N-phenylbenzenesulfonamide is obtained.
Then, N-phenylbenzenesulfonamide is modified. Nitro groups are introduced, and this step is mostly due to nitrification. Using a mixed strong acid of concentrated nitric acid and concentrated sulfuric acid as a medium, at a suitable temperature range, nitro groups are ingeniously connected to the benzene ring to form 3-nitro-N-phenylbenzenesulfonamide. In this process, temperature control is extremely important. If it is too high, it is easy to cause side reactions of polynitrification. If it is too low, the reaction is slow and the efficiency is not good.
Finally, to add chlorine atoms, chlorination reagents can be selected, such as chlorine-containing active compounds. Under the catalyst and specific conditions, chlorine atoms successfully replace hydrogen atoms at specific positions in the benzene ring, and finally 4-chloro-3-nitro-N-phenylbenzenesulfonamide This chlorination step also requires precise regulation of reaction conditions, such as reaction time and reagent dosage, to ensure the purity and yield of the product.
The whole process of synthesizing this compound, the fine control of the reaction conditions at each step, and the proper separation and purification of the intermediate products are all key to obtaining high purity 4-chloro-3-nitro-N-phenylbenzenesulfonamide.
What are the physical properties of 4-chloro-3-nitro-N-phenylbenzenesulfonamide?
4-Chloro-3-nitro-N-phenylbenzenesulfonamide, this is an organic compound. Its physical properties are crucial and related to many practical applications.
Looking at its appearance, it is often in a crystalline state, with a white and pure color, just like the whiteness of snow. The crystalline form is regular and orderly, the particles are delicate, and it shimmers under light, which is quite ornamental.
When it comes to the melting point, the melting point of this compound is within a certain range, about [specific melting point range]. The characteristics of the melting point are of great significance in the identification and purification of this substance. When heated to this temperature range, it gradually melts from a solid state to a liquid state, just like ice disappearing under the warm sun. This process is precise and controllable, providing convenience for chemical operations.
In terms of boiling point, there is also a specific value, which is about [specific boiling point range]. The level of boiling point affects the existence form of the substance under different temperature conditions. When the temperature rises to the boiling point, it will change from a liquid state to a gaseous state, just like water vapor evaporation. This property plays an important role in distillation separation and other processes.
Solubility is also one of its important physical properties. In organic solvents, such as ethanol and acetone, it has a certain solubility. In ethanol, just like fish getting water, some molecules are evenly dispersed to form a uniform and stable solution; in acetone, it can also dissolve well and show good affinity. However, in water, its solubility is very small, just like sand and gravel entering water, it is difficult to melt and difficult to melt, and most of them sink to the bottom. This difference in solubility provides an effective way for separation and purification.
In terms of density, there is also a corresponding value, which is about [specific density value]. Density represents the mass of its unit volume, and in practical applications, it is of great significance for the measurement and mixing ratio control of materials. The unique physical properties of 4-chloro-3-nitro-N-phenylbenzenesulfonamide are interrelated and have important uses in many fields such as chemical production and drug development, which is the key to research and application.
What are the safety precautions for 4-chloro-3-nitro-N-phenylbenzenesulfonamide?
4-Chloro-3-nitro-N-phenylbenzenesulfonamide is an organic compound. Regarding the safety precautions of this substance, the following numbers should be carefully examined:
First, this substance is toxic. Or it can invade the human body by inhalation, ingestion, skin contact, etc., harming health. When operating, be sure to wear protective clothing, gloves and goggles and other protective equipment, and work in a well-ventilated place to prevent inhalation of its dust or vapor. In case of accidental contact, rinse with plenty of water immediately. In serious cases, seek medical attention immediately.
Second, this substance is irritating. It is irritating to the eyes, skin, and respiratory tract. If it splashes into the eyes, the eyelids should be immediately opened, rinsed with flowing water or normal saline for several minutes, and then sent to the doctor. If it comes into contact with the skin, the contaminated clothes should be removed as soon as possible, and thoroughly washed with soap and water. If inhaling its steam or dust causes respiratory discomfort, it should leave the scene immediately and go to a fresh air place. If necessary, artificial respiration should be performed and sent to the doctor.
Third, its chemical properties are lively. When storing, it should be separated from oxidants, acids, alkalis, etc., and placed in a cool, dry, well-ventilated place, away from fire and heat sources to prevent dangerous chemical reactions. Handle with care during handling to avoid damage to the packaging.
Fourth, in view of the fact that this substance is an organic synthesis product, the waste generated during the synthesis and use process must not be discarded at will, and must be properly handled in accordance with relevant environmental regulations to prevent environmental pollution.
In short, when operating 4-chloro-3-nitro-N-phenylbenzenesulfonamide, it is necessary to strictly follow safety procedures and take comprehensive protection to ensure personal safety and the environment are not endangered.