Linshang Chemical
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4-Chloro-3-Nitro-N-Phenylbenzenesulphonamide
Linshang Chemical
|
HS Code |
875784 |
| Chemical Formula | C12H9ClN2O4S |
| Appearance | Typically a solid |
| Physical State At Room Temp | Solid |
| Solubility In Water | Low solubility in water |
| Solubility In Organic Solvents | Soluble in some organic solvents like ethanol, acetone |
| Melting Point | Varies, but generally in a specific range (data may be needed from literature) |
| Boiling Point | Data usually from literature, as it's difficult to predict without experimental values |
| Density | Specific density value can be found in relevant references |
| Pka | Value depends on the acidic/basic nature of relevant functional groups (literature - based) |
| Flash Point | Requires experimental determination or literature data |
| Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 4-Chloro-3-Nitro-N-Phenylbenzenesulphonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 4 - chloro - 3 - nitro - N - phenylbenzenesulphonamide in a sealed, labeled container. |
| Storage | 4 - chloro - 3 - nitro - N - phenylbenzenesulphonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, ignition sources, and incompatible substances like strong oxidizers and bases. Store in a tightly - sealed container to prevent moisture absorption and potential decomposition. Ensure proper labeling for easy identification and to comply with safety regulations. |
| Shipping | 4 - chloro - 3 - nitro - N - phenylbenzenesulphonamide is shipped in accordance with strict chemical regulations. Packed in sealed, corrosion - resistant containers, transported by specialized carriers to ensure safe and compliant delivery. |
Competitive 4-Chloro-3-Nitro-N-Phenylbenzenesulphonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 4-Chloro-3-Nitro-N-Phenylbenzenesulphonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemistry of 4-chloro-3-nitro-n-phenylbenzenesulphonamide?
4-Chloro-3-nitro-N-phenylbenzenesulfonamide, this is an organic compound with specific chemical properties.
Its appearance is often solid at room temperature, and the color is white or nearly white, powdery or crystalline. It is simple in appearance.
In terms of solubility, it may have a certain solubility in organic solvents, such as ethanol, acetone, etc. However, in water, the solubility may not be good. This is because the compound molecule contains benzene ring, sulfonamide group and other groups. The benzene ring is a hydrophobic structure, which makes it difficult to dissolve in water. The non-polar or weakly polar organic solvent is compatible with some groups of the compound, so it is soluble. In terms of chemical stability of
, the intramolecular chemical bond interactions are complicated. In the sulfonamide group, the sulfur-nitrogen bond has a certain stability, but the presence of chlorine atoms and nitro groups on the benzene ring, or the change of the electron cloud density of the benzene ring, make its chemical activity different. Nitro is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring and weaken the electrophilic substitution activity of the benzene ring. However, the electron cloud density of the ortho and para-site is relatively low, and the activity of the nucleophilic substitution reaction may change.
Whether its chemical properties are active or not depends on the specific reaction scene. In case of nucleophilic reagents, or nucleophilic substitution reactions occur at specific positions in the benzene ring, chlorine atoms may be In case of reducing agent, the nitro group may be reduced to amino group, which is due to the interaction of various groups in the compound, resulting in complex and multi-terminal chemical properties.
When heated, decomposition reactions may occur, and the decomposition products may be small molecule compounds containing chlorine and nitrogen, or other organic fragments may be formed. In summary, the chemical properties of 4-chloro-3-nitro-N-phenylbenzenesulfonamide are determined by its structure. Each group interacts and exhibits a variety of chemical behaviors under different conditions. It may have unique uses and reaction characteristics in the fields of organic synthesis, medicinal chemistry, etc.
Its appearance is often solid at room temperature, and the color is white or nearly white, powdery or crystalline. It is simple in appearance.
In terms of solubility, it may have a certain solubility in organic solvents, such as ethanol, acetone, etc. However, in water, the solubility may not be good. This is because the compound molecule contains benzene ring, sulfonamide group and other groups. The benzene ring is a hydrophobic structure, which makes it difficult to dissolve in water. The non-polar or weakly polar organic solvent is compatible with some groups of the compound, so it is soluble. In terms of chemical stability of
, the intramolecular chemical bond interactions are complicated. In the sulfonamide group, the sulfur-nitrogen bond has a certain stability, but the presence of chlorine atoms and nitro groups on the benzene ring, or the change of the electron cloud density of the benzene ring, make its chemical activity different. Nitro is a strong electron-absorbing group, which can reduce the electron cloud density of the benzene ring and weaken the electrophilic substitution activity of the benzene ring. However, the electron cloud density of the ortho and para-site is relatively low, and the activity of the nucleophilic substitution reaction may change.
Whether its chemical properties are active or not depends on the specific reaction scene. In case of nucleophilic reagents, or nucleophilic substitution reactions occur at specific positions in the benzene ring, chlorine atoms may be In case of reducing agent, the nitro group may be reduced to amino group, which is due to the interaction of various groups in the compound, resulting in complex and multi-terminal chemical properties.
When heated, decomposition reactions may occur, and the decomposition products may be small molecule compounds containing chlorine and nitrogen, or other organic fragments may be formed. In summary, the chemical properties of 4-chloro-3-nitro-N-phenylbenzenesulfonamide are determined by its structure. Each group interacts and exhibits a variety of chemical behaviors under different conditions. It may have unique uses and reaction characteristics in the fields of organic synthesis, medicinal chemistry, etc.
What are the uses of 4-chloro-3-nitro-n-phenylbenzenesulphonamide?
4-Chloro-3-nitro-N-phenylbenzenesulfonamide is an organic compound. It has a wide range of uses and has important effects in many fields.
In the field of medicine, it can be used as a pharmaceutical intermediate. Due to the special structure of this compound, it can provide a key basis for the synthesis of specific drugs. By subsequent modification and transformation of its structure, drugs with unique pharmacological activities can be prepared, or used to treat specific diseases, or to help develop new drug therapies.
In the field of pesticides, 4-chloro-3-nitro-N-phenylbenzenesulfonamide also has important value. It can be used as an important raw material for pesticide synthesis to prepare pesticide products with insecticidal, bactericidal or weeding effects. Its structural characteristics endow the pesticide synthesized with specific biological activities, which can effectively target various crop pests, pathogens or weeds, thereby ensuring the healthy growth of crops and improving crop yield and quality.
In the field of materials science, this compound may contribute to the research and development of new materials. With its unique chemical properties, or can participate in the modification process of materials, it endows materials with special properties such as better stability and corrosion resistance, thereby expanding the application range of materials and meeting the special needs of different fields for material properties.
Furthermore, in the study of organic synthesis chemistry, 4-chloro-3-nitro-N-phenylbenzenesulfonamide is often used as an important starting material or intermediate. Chemists can build more complex and diverse organic molecular structures through various organic reactions based on this compound, so as to explore the synthesis methods and properties of new organic compounds, and promote the development of organic synthesis chemistry. In short, 4-chloro-3-nitro-N-phenylbenzenesulfonamide plays an indispensable role in many fields.
In the field of medicine, it can be used as a pharmaceutical intermediate. Due to the special structure of this compound, it can provide a key basis for the synthesis of specific drugs. By subsequent modification and transformation of its structure, drugs with unique pharmacological activities can be prepared, or used to treat specific diseases, or to help develop new drug therapies.
In the field of pesticides, 4-chloro-3-nitro-N-phenylbenzenesulfonamide also has important value. It can be used as an important raw material for pesticide synthesis to prepare pesticide products with insecticidal, bactericidal or weeding effects. Its structural characteristics endow the pesticide synthesized with specific biological activities, which can effectively target various crop pests, pathogens or weeds, thereby ensuring the healthy growth of crops and improving crop yield and quality.
In the field of materials science, this compound may contribute to the research and development of new materials. With its unique chemical properties, or can participate in the modification process of materials, it endows materials with special properties such as better stability and corrosion resistance, thereby expanding the application range of materials and meeting the special needs of different fields for material properties.
Furthermore, in the study of organic synthesis chemistry, 4-chloro-3-nitro-N-phenylbenzenesulfonamide is often used as an important starting material or intermediate. Chemists can build more complex and diverse organic molecular structures through various organic reactions based on this compound, so as to explore the synthesis methods and properties of new organic compounds, and promote the development of organic synthesis chemistry. In short, 4-chloro-3-nitro-N-phenylbenzenesulfonamide plays an indispensable role in many fields.
What is 4-chloro-3-nitro-n-phenylbenzenesulphonamide synthesis method?
The synthesis of 4-chloro-3-nitro-N-phenylbenzenesulfonamide requires several delicate steps. The starting materials should be benzenesulfonyl chloride and aniline. When the two meet, N-phenylbenzenesulfonamide can be produced.
The first step is to take an appropriate amount of benzenesulfonyl chloride and place it in a clean reaction vessel. Aniline is slowly dripped in, and the reaction temperature should be paid attention to, and it should be controlled in an ice-water bath so that it does not overheat. Because the reaction between the two is violent, if the temperature is too high, side reactions may occur. During this process, stirring must be uniform and continuous, so that the two are fully contacted and the reaction is more complete. After the reaction is completed, the crude product of N-phenylbenzenesulfonamide is obtained by conventional separation methods, such as extraction and filtration. After recrystallization, a pure product is obtained.
In the next step, the obtained N-phenylbenzenesulfonamide is transferred to another reaction vessel, and the chlorine source and nitro source are introduced. Chlorine gas or chlorine-containing reagents are often selected for the chlorine source, and the nitro source is a mixed acid of concentrated nitric acid and concentrated sulfuric acid. At the beginning of the reaction, the mixed acid must be added slowly, and the temperature should be strictly controlled. Nitric acid is strongly oxidizing, and sulfuric acid can help it ionize nitroyl positive ions. The synergistic effect of the two makes the benzene ring electrophilic substitution. The introduction location of chlorine atoms and nitro groups depends The structure of 4-chloro-3-nitro-N-phenylbenzenesulfonamide determines that the chlorine atom should be at the 4th position and the nitro group at the 3rd position.
After the reaction is completed, the product is treated by neutralization, washing with water, drying and other steps. During neutralization, an appropriate amount of alkali solution is used to adjust the system to neutral. Washing with water can remove impurities, and drying makes the product pure and moisture-free. Finally, high-purity 4-chloro-3-nitro-N-phenylbenzenesulfonamide is obtained by column chromatography or recrystallization. The whole synthesis process requires fine operation and strict control of conditions to achieve good yield and purity.
The first step is to take an appropriate amount of benzenesulfonyl chloride and place it in a clean reaction vessel. Aniline is slowly dripped in, and the reaction temperature should be paid attention to, and it should be controlled in an ice-water bath so that it does not overheat. Because the reaction between the two is violent, if the temperature is too high, side reactions may occur. During this process, stirring must be uniform and continuous, so that the two are fully contacted and the reaction is more complete. After the reaction is completed, the crude product of N-phenylbenzenesulfonamide is obtained by conventional separation methods, such as extraction and filtration. After recrystallization, a pure product is obtained.
In the next step, the obtained N-phenylbenzenesulfonamide is transferred to another reaction vessel, and the chlorine source and nitro source are introduced. Chlorine gas or chlorine-containing reagents are often selected for the chlorine source, and the nitro source is a mixed acid of concentrated nitric acid and concentrated sulfuric acid. At the beginning of the reaction, the mixed acid must be added slowly, and the temperature should be strictly controlled. Nitric acid is strongly oxidizing, and sulfuric acid can help it ionize nitroyl positive ions. The synergistic effect of the two makes the benzene ring electrophilic substitution. The introduction location of chlorine atoms and nitro groups depends The structure of 4-chloro-3-nitro-N-phenylbenzenesulfonamide determines that the chlorine atom should be at the 4th position and the nitro group at the 3rd position.
After the reaction is completed, the product is treated by neutralization, washing with water, drying and other steps. During neutralization, an appropriate amount of alkali solution is used to adjust the system to neutral. Washing with water can remove impurities, and drying makes the product pure and moisture-free. Finally, high-purity 4-chloro-3-nitro-N-phenylbenzenesulfonamide is obtained by column chromatography or recrystallization. The whole synthesis process requires fine operation and strict control of conditions to achieve good yield and purity.
What are the physical properties of 4-chloro-3-nitro-n-phenylbenzenesulphonamide?
4-Chloro-3-nitro-N-phenylbenzenesulfonamide, this is a kind of organic compound. Its physical properties are quite important and are related to many practical applications.
First of all, its appearance is usually in the shape of a crystalline powder, which is easy to store and use. In many chemical reaction systems, the powdered substance can be more fully contacted with other reactants to promote the progress of the reaction.
As for the color, it is mostly white to light yellow. The appearance of this color is due to the electron cloud distribution and electron transition characteristics of each atom in its molecular structure, which affect its visual recognition in different environments.
Melting point is also one of the key physical properties. Its melting point is within a certain range. This characteristic determines the temperature conditions required for the substance to change from solid to liquid. In the process of material processing and purification, melting point data can help determine the purity of the substance and select the appropriate treatment temperature. If the melting point deviates from the normal range, or indicates that the substance contains impurities, further purification is required.
In terms of solubility, 4-chloro-3-nitro-N-phenylbenzenesulfonamide has a certain solubility in common organic solvents such as ethanol and acetone, but it has poor solubility in water. This property is closely related to the polarity of the molecule. Its molecular structure contains both polar groups and large non-polar benzene ring structures, resulting in different dissolution behaviors in different polar solvents. In organic synthesis, according to this difference in solubility, suitable solvents can be selected for reaction, separation and purification operations.
In addition, its density also has specific values, although it is not a very prominent property. However, in operations involving accurate measurement and mixing ratios, density data is indispensable, which can help determine the quality of the substance in a specific volume and ensure the accuracy of the experiment and production process.
In summary, the physical properties of 4-chloro-3-nitro-N-phenylbenzenesulfonamide are of great significance in the fields of organic synthesis and materials science, and provide key basic data for related processes and research.
First of all, its appearance is usually in the shape of a crystalline powder, which is easy to store and use. In many chemical reaction systems, the powdered substance can be more fully contacted with other reactants to promote the progress of the reaction.
As for the color, it is mostly white to light yellow. The appearance of this color is due to the electron cloud distribution and electron transition characteristics of each atom in its molecular structure, which affect its visual recognition in different environments.
Melting point is also one of the key physical properties. Its melting point is within a certain range. This characteristic determines the temperature conditions required for the substance to change from solid to liquid. In the process of material processing and purification, melting point data can help determine the purity of the substance and select the appropriate treatment temperature. If the melting point deviates from the normal range, or indicates that the substance contains impurities, further purification is required.
In terms of solubility, 4-chloro-3-nitro-N-phenylbenzenesulfonamide has a certain solubility in common organic solvents such as ethanol and acetone, but it has poor solubility in water. This property is closely related to the polarity of the molecule. Its molecular structure contains both polar groups and large non-polar benzene ring structures, resulting in different dissolution behaviors in different polar solvents. In organic synthesis, according to this difference in solubility, suitable solvents can be selected for reaction, separation and purification operations.
In addition, its density also has specific values, although it is not a very prominent property. However, in operations involving accurate measurement and mixing ratios, density data is indispensable, which can help determine the quality of the substance in a specific volume and ensure the accuracy of the experiment and production process.
In summary, the physical properties of 4-chloro-3-nitro-N-phenylbenzenesulfonamide are of great significance in the fields of organic synthesis and materials science, and provide key basic data for related processes and research.
What is the price range of 4-chloro-3-nitro-n-phenylbenzenesulphonamide in the market?
4-Chloro-3-nitro-N-phenylbenzenesulfonamide, the market price is not easy to determine. This is a chemical in the field of fine chemicals, and its price involves many factors and is complex.
The first to bear the brunt is the price of raw materials. If the price of chlorobenzene, nitrobenzene, aniline and other raw materials used in the synthesis of this amide fluctuates due to the trend of supply and demand, the distance of origin, and the difficulty of production, the price of 4-chloro-3-nitro-N-phenylbenzenesulfonamide will also change. If the raw materials are abundant and the price is flat, the cost of production will drop, and the price will be close to the people at the market price. On the contrary, if the raw materials are scarce and expensive, the price will also rise.
Furthermore, the production process is related to the cost. Fine craftsmanship requires sophisticated equipment, high technology, and may require multiple purification and refining processes, and energy consumption is also large, which all increases the production cost, resulting in high prices in the market. And the process is simple, although the cost may drop, the quality is difficult to predict, and the price will also be affected.
In addition, the supply and demand of the market determines the price. If this amide is in high demand in the pharmaceutical, pesticide and other industries, but the supply is limited, the price will rise; if the supply exceeds the demand, the manufacturer will sell its goods or reduce the price.
Also, the price varies depending on the quality. High purity and high quality are suitable for high-end fields, and the price is not cheap; those with inferior quality may have a slightly lower price.
And the price varies depending on the region. In prosperous cities, due to high logistics, warehousing, and labor costs, the price may be higher than in remote places.
Overall, the market price of 4-chloro-3-nitro-N-phenylbenzenesulfonamide ranges from tens of yuan to hundreds of yuan per kilogram, but this is only an approximation. The actual price must be determined according to the time and market.
The first to bear the brunt is the price of raw materials. If the price of chlorobenzene, nitrobenzene, aniline and other raw materials used in the synthesis of this amide fluctuates due to the trend of supply and demand, the distance of origin, and the difficulty of production, the price of 4-chloro-3-nitro-N-phenylbenzenesulfonamide will also change. If the raw materials are abundant and the price is flat, the cost of production will drop, and the price will be close to the people at the market price. On the contrary, if the raw materials are scarce and expensive, the price will also rise.
Furthermore, the production process is related to the cost. Fine craftsmanship requires sophisticated equipment, high technology, and may require multiple purification and refining processes, and energy consumption is also large, which all increases the production cost, resulting in high prices in the market. And the process is simple, although the cost may drop, the quality is difficult to predict, and the price will also be affected.
In addition, the supply and demand of the market determines the price. If this amide is in high demand in the pharmaceutical, pesticide and other industries, but the supply is limited, the price will rise; if the supply exceeds the demand, the manufacturer will sell its goods or reduce the price.
Also, the price varies depending on the quality. High purity and high quality are suitable for high-end fields, and the price is not cheap; those with inferior quality may have a slightly lower price.
And the price varies depending on the region. In prosperous cities, due to high logistics, warehousing, and labor costs, the price may be higher than in remote places.
Overall, the market price of 4-chloro-3-nitro-N-phenylbenzenesulfonamide ranges from tens of yuan to hundreds of yuan per kilogram, but this is only an approximation. The actual price must be determined according to the time and market.
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