Linshang Chemical
PRODUCTS
4-Chloro-3-Nitrobenzenesulfonamide
Linshang Chemical
|
HS Code |
961294 |
| Chemical Formula | C6H5ClN2O5S |
| Molecular Weight | 254.63 |
| Appearance | Solid (usually a powder) |
| Physical State At Room Temperature | Solid |
| Odor | Typically odorless or faint |
| Solubility In Water | Low solubility |
| Solubility In Organic Solvents | Moderate solubility in some organic solvents |
| Melting Point | Approximately 157 - 161 °C |
| Boiling Point | Decomposes before boiling |
| Ph | Neutral in solid form, but may react in solution to affect pH |
| Stability | Stable under normal conditions, but may react with strong oxidizing or reducing agents |
As an accredited 4-Chloro-3-Nitrobenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 4 - chloro - 3 - nitrobenzenesulfonamide in a sealed, labeled chemical - grade bag. |
| Storage | 4 - chloro - 3 - nitrobenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, ignition sources, and incompatible substances like strong oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and potential reactions. Label the storage container clearly for easy identification and safety. |
| Shipping | 4 - chloro - 3 - nitrobenzenesulfonamide is shipped in sealed, corrosion - resistant containers. It must comply with hazardous chemical shipping regulations, ensuring proper labeling, secure packaging to prevent spills during transit. |
Competitive 4-Chloro-3-Nitrobenzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Chloro-3-Nitrobenzenesulfonamide in China?
As a trusted 4-Chloro-3-Nitrobenzenesulfonamide manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Chloro-3-Nitrobenzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 4-chloro-3-nitrobenzenesulfonamide?
The chemical structure of 4-chloro-3-nitrobenzenesulfonamide is a category of organic compounds. This compound is based on a benzene ring, with a chlorine atom at No. 4 and a nitro group at No. 3 above the benzene ring, and a sulfonamide group connected to the benzene ring.
Its benzene ring is a six-membered carbon ring, which has a conjugated system, endowing the compound with certain stability. The chlorine atom at No. 4 is a halogen atom, and the electronegativity of chlorine is relatively large, which has an impact on the distribution of electron clouds in the benzene ring, which can cause changes in the density of electron clouds in the adjacent and para-sites of the benzene ring. In chemical The nitro group at position 3
is a strong electron-absorbing group. Its existence greatly reduces the electron cloud density of the benzene ring, and decreases the electrophilic substitution activity of the benzene ring. At the same time, the nitro group has a significant impact on the ortho and para-sites, which can change the chemical environment of the ortho and para-site hydrogen atoms.
The sulfonamide group is composed of a sulfonyl group (-SO2O -) connected to an amino group (-NH 2O). The sulfur atom in the sulfonyl group has a high oxidation state and has a certain electrophilicity, and the nitrogen atom of the amino group has a lone pair electron, which has a certain nucleophilicity and basicity. The sulfonamide group not only affects the physical properties of the compound, such as solubility, but also affects its chemical properties. It can participate in many reactions, such as reactions with acids and bases.
In summary, the chemical structure of 4-chloro-3-nitrobenzenesulfonamide is composed of benzene ring, chlorine atom, nitro group and sulfonamide group. The interaction of each part determines the unique physical and chemical properties of the compound.
Its benzene ring is a six-membered carbon ring, which has a conjugated system, endowing the compound with certain stability. The chlorine atom at No. 4 is a halogen atom, and the electronegativity of chlorine is relatively large, which has an impact on the distribution of electron clouds in the benzene ring, which can cause changes in the density of electron clouds in the adjacent and para-sites of the benzene ring. In chemical The nitro group at position 3
is a strong electron-absorbing group. Its existence greatly reduces the electron cloud density of the benzene ring, and decreases the electrophilic substitution activity of the benzene ring. At the same time, the nitro group has a significant impact on the ortho and para-sites, which can change the chemical environment of the ortho and para-site hydrogen atoms.
The sulfonamide group is composed of a sulfonyl group (-SO2O -) connected to an amino group (-NH 2O). The sulfur atom in the sulfonyl group has a high oxidation state and has a certain electrophilicity, and the nitrogen atom of the amino group has a lone pair electron, which has a certain nucleophilicity and basicity. The sulfonamide group not only affects the physical properties of the compound, such as solubility, but also affects its chemical properties. It can participate in many reactions, such as reactions with acids and bases.
In summary, the chemical structure of 4-chloro-3-nitrobenzenesulfonamide is composed of benzene ring, chlorine atom, nitro group and sulfonamide group. The interaction of each part determines the unique physical and chemical properties of the compound.
What are the main uses of 4-chloro-3-nitrobenzenesulfonamide?
4-Chloro-3-nitrobenzenesulfonamide is one of the organic compounds. It has a wide range of uses and has important functions in many fields such as medicine, pesticides and material science.
In the field of medicine, this compound is often used as a key intermediate for the synthesis of various drugs. Due to its special chemical structure, it can interact with specific targets in organisms and exhibit pharmacological activities such as antibacterial and anti-inflammatory. Or it can be modified by specific chemical reactions to meet the needs of drug design and develop new therapeutic drugs.
In the field of pesticides, 4-chloro-3-nitrobenzenesulfonamide also plays an important role. It can be used as a raw material for the synthesis of highly efficient pesticides. With its special mechanism of action against certain pests or pathogens, it can help to develop highly targeted and effective pesticide products to ensure the growth and yield of crops.
In the field of materials science, this compound can participate in material synthesis. Through its chemical properties, it reacts with other substances and imparts specific properties to the material, such as improving the stability and optical properties of the material, so it can be used in the preparation of many advanced materials.
In summary, 4-chloro-3-nitrobenzenesulfonamide is an indispensable substance in the fields of medicine, pesticides and materials science, and plays an important role in promoting the development of various fields.
In the field of medicine, this compound is often used as a key intermediate for the synthesis of various drugs. Due to its special chemical structure, it can interact with specific targets in organisms and exhibit pharmacological activities such as antibacterial and anti-inflammatory. Or it can be modified by specific chemical reactions to meet the needs of drug design and develop new therapeutic drugs.
In the field of pesticides, 4-chloro-3-nitrobenzenesulfonamide also plays an important role. It can be used as a raw material for the synthesis of highly efficient pesticides. With its special mechanism of action against certain pests or pathogens, it can help to develop highly targeted and effective pesticide products to ensure the growth and yield of crops.
In the field of materials science, this compound can participate in material synthesis. Through its chemical properties, it reacts with other substances and imparts specific properties to the material, such as improving the stability and optical properties of the material, so it can be used in the preparation of many advanced materials.
In summary, 4-chloro-3-nitrobenzenesulfonamide is an indispensable substance in the fields of medicine, pesticides and materials science, and plays an important role in promoting the development of various fields.
What are the physical properties of 4-chloro-3-nitrobenzenesulfonamide?
4-Chloro-3-nitrobenzenesulfonamide is one of the organic compounds. Its physical properties are particularly important and are listed as follows:
First appearance, under room temperature and pressure, 4-chloro-3-nitrobenzenesulfonamide is mostly white to light yellow crystalline powder. This color feature is quite critical in identifying this substance. It can be preliminarily judged by observing its color and state.
times and melting point, after fine determination, its melting point is about 170-174 ° C. The melting point is the inherent physical constant of the substance, which plays a significant role in identifying the compound and measuring its purity. If the melting point of the sample is in line with the stated range and the melting range is very narrow, it is sufficient to prove that its purity is high; conversely, if the melting point deviates from this range or the melting range is too wide, it indicates that the sample may contain impurities.
The other is solubility. This substance has different solubility in common organic solvents. In water, its solubility is very small, because the molecular polarity of the compound is quite different from that of water, it is difficult to form an effective interaction. However, in some polar organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), it exhibits good solubility. This property is of great significance in the fields of organic synthesis, drug development, etc. Researchers can choose suitable solvents according to their solubility to promote the reaction process or carry out related experiments.
In terms of density, although its exact value varies depending on the measurement conditions, it is generally within a certain range. The value of density is related to its distribution in the mixed system, and is an indispensable consideration in chemical production, separation and purification.
In addition, the stability of 4-chloro-3-nitrobenzenesulfonamide also belongs to the category of physical properties. In a dry and dark environment at room temperature, its properties are relatively stable, but if exposed to high temperature, humidity or strong light, or chemical changes such as decomposition occur, its physical properties will also change. In summary, the physical properties of 4-chloro-3-nitrobenzenesulfonamide, including its appearance, melting point, solubility, density, and stability, have a profound impact on its research, application, and treatment methods. Researchers and practitioners must be well informed in order to make good use of this substance.
First appearance, under room temperature and pressure, 4-chloro-3-nitrobenzenesulfonamide is mostly white to light yellow crystalline powder. This color feature is quite critical in identifying this substance. It can be preliminarily judged by observing its color and state.
times and melting point, after fine determination, its melting point is about 170-174 ° C. The melting point is the inherent physical constant of the substance, which plays a significant role in identifying the compound and measuring its purity. If the melting point of the sample is in line with the stated range and the melting range is very narrow, it is sufficient to prove that its purity is high; conversely, if the melting point deviates from this range or the melting range is too wide, it indicates that the sample may contain impurities.
The other is solubility. This substance has different solubility in common organic solvents. In water, its solubility is very small, because the molecular polarity of the compound is quite different from that of water, it is difficult to form an effective interaction. However, in some polar organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), it exhibits good solubility. This property is of great significance in the fields of organic synthesis, drug development, etc. Researchers can choose suitable solvents according to their solubility to promote the reaction process or carry out related experiments.
In terms of density, although its exact value varies depending on the measurement conditions, it is generally within a certain range. The value of density is related to its distribution in the mixed system, and is an indispensable consideration in chemical production, separation and purification.
In addition, the stability of 4-chloro-3-nitrobenzenesulfonamide also belongs to the category of physical properties. In a dry and dark environment at room temperature, its properties are relatively stable, but if exposed to high temperature, humidity or strong light, or chemical changes such as decomposition occur, its physical properties will also change. In summary, the physical properties of 4-chloro-3-nitrobenzenesulfonamide, including its appearance, melting point, solubility, density, and stability, have a profound impact on its research, application, and treatment methods. Researchers and practitioners must be well informed in order to make good use of this substance.
What is 4-chloro-3-nitrobenzenesulfonamide synthesis method?
The synthesis of 4-chloro-3-nitrobenzenesulfonamide is an important topic in the field of organic synthesis. Its synthesis often follows the following steps.
The starting material is mostly benzenesulfonamide, which can be used as a reaction basis because its structure contains sulfonamide groups. To introduce chlorine and nitro groups at specific positions in the benzene ring, a suitable chemical reaction is required.
The chlorination reaction is often achieved by chlorination reagents. For example, chlorine gas reacts with benzenesulfonamide in the presence of a specific catalyst, such as iron or ferric chloride. This reaction can introduce chlorine atoms into the benzene ring. The reaction conditions are very critical, and the temperature, reaction time and reagent dosage need to be precisely controlled. Usually, the appropriate temperature is within a certain range. If the temperature is too high, the side reactions will increase, and if it is too low, the reaction rate will be too slow.
Nitrification reaction, mixed acid (a mixture of nitric acid and sulfuric acid) is often used as a nitrification reagent. The effect of sulfuric acid, one is to enhance the activity of nitric acid, and the other is to promote the right shift of the reaction equilibrium. The chlorinated product is reacted with mixed acid, and the nitro group can be introduced into the benzene ring. Similarly, the reaction temperature, time and concentration of mixed acid need to be strictly controlled. If the temperature is too high, it is easy to cause the formation of polynitrification products; if the time is too short, the reaction is incomplete.
After the chlorination and nitrification are completed, the separation and purification Recrystallization takes advantage of differences in solubility in different solvents and crystallizes multiple times in suitable solvents for purification purposes. Column chromatography uses the difference in adsorption and partition coefficients of different substances between stationary and mobile phases to achieve separation.
Synthesis of 4-chloro-3-nitrobenzenesulfonamide, each step is closely linked, the precise regulation of reaction conditions and the effective separation and purification of the product are the keys to obtain high-purity target products.
The starting material is mostly benzenesulfonamide, which can be used as a reaction basis because its structure contains sulfonamide groups. To introduce chlorine and nitro groups at specific positions in the benzene ring, a suitable chemical reaction is required.
The chlorination reaction is often achieved by chlorination reagents. For example, chlorine gas reacts with benzenesulfonamide in the presence of a specific catalyst, such as iron or ferric chloride. This reaction can introduce chlorine atoms into the benzene ring. The reaction conditions are very critical, and the temperature, reaction time and reagent dosage need to be precisely controlled. Usually, the appropriate temperature is within a certain range. If the temperature is too high, the side reactions will increase, and if it is too low, the reaction rate will be too slow.
Nitrification reaction, mixed acid (a mixture of nitric acid and sulfuric acid) is often used as a nitrification reagent. The effect of sulfuric acid, one is to enhance the activity of nitric acid, and the other is to promote the right shift of the reaction equilibrium. The chlorinated product is reacted with mixed acid, and the nitro group can be introduced into the benzene ring. Similarly, the reaction temperature, time and concentration of mixed acid need to be strictly controlled. If the temperature is too high, it is easy to cause the formation of polynitrification products; if the time is too short, the reaction is incomplete.
After the chlorination and nitrification are completed, the separation and purification Recrystallization takes advantage of differences in solubility in different solvents and crystallizes multiple times in suitable solvents for purification purposes. Column chromatography uses the difference in adsorption and partition coefficients of different substances between stationary and mobile phases to achieve separation.
Synthesis of 4-chloro-3-nitrobenzenesulfonamide, each step is closely linked, the precise regulation of reaction conditions and the effective separation and purification of the product are the keys to obtain high-purity target products.
4-chloro-3-nitrobenzenesulfonamide what are the precautions during use
4-Chloro-3-nitrobenzenesulfonamide is also a chemical substance. When using, many things must not be ignored.
First safety protection. This substance is dangerous to a certain extent, or irritates the skin, eyes and respiratory tract. Therefore, the user must wear appropriate protective equipment, such as gloves, protective glasses and masks. If it accidentally touches the skin or eyes, rinse with plenty of water as soon as possible and seek medical attention in time.
Furthermore, it is related to storage. It should be stored in a cool, dry and well-ventilated place, away from fire sources, heat sources and oxidants. Due to its active chemical properties, improper storage may cause dangerous accidents.
When using, operate with precision and must not be ignored. Strictly follow the experimental procedures or production requirements, and control the dosage and reaction conditions. This substance may participate in a specific chemical reaction, and the conditions are slightly deviated, which may affect the quality of the product and even cause safety problems.
In addition, properly dispose of waste. After use, the remaining 4-chloro-3-nitrobenzenesulfonamide and related waste cannot be discarded at will. It needs to be sorted, collected and disposed of in accordance with relevant environmental regulations to avoid polluting the environment.
In addition, it is also important to be familiar with its chemical properties and emergency treatment methods. Users must understand its reaction characteristics under different conditions, and in case of emergencies, such as leakage, fire, etc., they can respond quickly and correctly to reduce the harm.
In short, with 4-chloro-3-nitrobenzenesulfonamide, caution is essential, safety first, and standardized operation can ensure smooth operation.
First safety protection. This substance is dangerous to a certain extent, or irritates the skin, eyes and respiratory tract. Therefore, the user must wear appropriate protective equipment, such as gloves, protective glasses and masks. If it accidentally touches the skin or eyes, rinse with plenty of water as soon as possible and seek medical attention in time.
Furthermore, it is related to storage. It should be stored in a cool, dry and well-ventilated place, away from fire sources, heat sources and oxidants. Due to its active chemical properties, improper storage may cause dangerous accidents.
When using, operate with precision and must not be ignored. Strictly follow the experimental procedures or production requirements, and control the dosage and reaction conditions. This substance may participate in a specific chemical reaction, and the conditions are slightly deviated, which may affect the quality of the product and even cause safety problems.
In addition, properly dispose of waste. After use, the remaining 4-chloro-3-nitrobenzenesulfonamide and related waste cannot be discarded at will. It needs to be sorted, collected and disposed of in accordance with relevant environmental regulations to avoid polluting the environment.
In addition, it is also important to be familiar with its chemical properties and emergency treatment methods. Users must understand its reaction characteristics under different conditions, and in case of emergencies, such as leakage, fire, etc., they can respond quickly and correctly to reduce the harm.
In short, with 4-chloro-3-nitrobenzenesulfonamide, caution is essential, safety first, and standardized operation can ensure smooth operation.
Scan to WhatsApp
