4-Chloro-3-Nitrobenzenesulfonic Acid, Sodium Salt
Linshang Chemical
HS Code |
994295 |
Chemical Formula | C6H3ClNNaO5S |
Molar Mass | 269.60 g/mol |
Appearance | yellowish powder or crystals |
Solubility | soluble in water |
Melting Point | decomposes |
Ph | alkaline in aqueous solution |
Stability | stable under normal conditions, but avoid strong oxidizing agents |
Hazard Class | irritant, may cause eye, skin and respiratory tract irritation |
Use | used in the synthesis of dyes, pigments and other organic compounds |
As an accredited 4-Chloro-3-Nitrobenzenesulfonic Acid, Sodium Salt factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 4 - chloro - 3 - nitrobenzenesulfonic Acid, Sodium Salt in sealed chemical - grade packaging. |
Storage | 4 - Chloro - 3 - nitrobenzenesulfonic acid, sodium salt should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and potential reactions. This helps maintain its chemical stability and reduces the risk of hazardous incidents. |
Shipping | 4 - Chloro - 3 - nitrobenzenesulfonic acid, sodium salt should be shipped in tightly - sealed containers. It must be handled as a hazardous chemical, following all safety regulations to prevent spills and ensure safe transportation. |
Competitive 4-Chloro-3-Nitrobenzenesulfonic Acid, Sodium Salt prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 4-Chloro-3-Nitrobenzenesulfonic Acid, Sodium Salt supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Looking at its physical properties, it is usually a white to light gray crystalline powder, odorless, with a certain degree of hygroscopicity. In water, it dissolves quite well, which makes it easy to play a role in many aqueous systems.
When it comes to chemical properties, this substance exhibits unique reactivity due to its rich chlorine atoms, nitro groups and sulfonic acid groups in its molecular structure. Chlorine atoms have certain substitution activities. Under appropriate conditions, they can be replaced by other nucleophiles to derive a variety of organic compounds. The nitro group is a strong electron-absorbing group, which not only reduces the electron cloud density of the benzene ring and enhances its chemical stability, but also endows the compound with certain oxidizing properties. In specific chemical reactions, it can be used as an oxidizing agent or participate in electrophilic substitution reactions. The sulfonic acid group makes the compound acidic and can neutralize with bases to form corresponding salts.
4-chloro-3-nitrobenzene sulfonate sodium is widely used in the field of organic synthesis and is often used as an important intermediate for the preparation of a variety of fine chemicals such as medicines, dyes and pesticides. Because of its active chemical properties and ability to participate in many types of chemical reactions, it is favored by organic synthesis chemists and occupies an indispensable position in the modern chemical industry.
In the pharmaceutical field, it is often used as an intermediate in organic synthesis. In the synthesis process of many drugs, it can be used as a starting material or participate in key reaction steps, and through a series of chemical transformations, an effective drug for treating diseases can be obtained. It is like building the cornerstone of a delicate medicine stone building, laying the foundation for the synthesis of specific drugs.
In leather manufacturing, it also has important uses. It can help the leather tanning process to be smoother, improve the softness, durability and water resistance of leather, and make leather products more refined and durable. Just like the help of leather craftsmen to the fine crafting of leather, giving leather better quality.
In addition, in some industrial cleaning agent formulations, sodium 4-chloro-3-nitrobenzene sulfonate is also used. With its special chemical properties, it can effectively remove oil stains, stains, etc., and achieve good cleaning results. Like a strong general in the industrial cleaning army, it contributes to the cleaning of various instruments and equipment.
First take benzene as the starting material, use chlorine as the reagent, and under the catalysis of ferric chloride, make benzene and chlorine substitution reaction to obtain chlorobenzene. This reaction needs to be controlled at a certain temperature range to make the reaction proceed smoothly, and there are many para-and ortho-substituted products, but the main product is chlorobenzene.
Then, make chlorobenzene react with mixed acid (mixture of nitric acid and sulfuric acid), nitric acid under the action of sulfuric acid produces nitroyl positive ion, which is an electrophilic reagent, and undergoes an electrophilic substitution reaction with chlorobenzene. Nitro is introduced into the ortho-position of chlorob In this step, the reaction conditions need to be precisely controlled. The ratio of sulfuric acid to nitric acid and the reaction temperature all affect the yield and purity of the product.
Then, with o-nitrochlorobenzene as the substrate, the sulfonation reaction is carried out by co-heating with fuming sulfuric acid. The sulfonic acid group (-SO 🥰 H) replaces the hydrogen at a specific position on the benzene ring to obtain 4-chloro-3-nitrobenzene sulfonic acid. In this reaction, factors such as the concentration of fuming sulfuric acid, reaction time and temperature are critical, which affect the location and degree of sulfonic acid group introduction.
Finally, 4-chloro-3-nitrobenzenesulfonic acid is reacted with a base such as sodium hydroxide or sodium carbonate, and the hydrogen of the sulfonic acid group is replaced by sodium ions to obtain 4-chloro-3-nitrobenzenesulfonic acid sodium salt. After the reaction, after crystallization, filtration, washing, drying and other steps, a pure product can be obtained.
After each step of the reaction, it needs to be separated and purified, such as distillation, extraction, recrystallization, etc., to remove impurities and extract the purity of the product, so that the product of each step meets the requirements of the next reaction, so that the sodium salt of 4-chloro-3-nitrobenzenesulfonic acid can be effectively synthesized.
First words storage, this chemical material should be stored in a cool and dry place. Because of its fear of heat and moisture, if it is placed in a high temperature and humid place, it may cause changes in its properties, affecting its quality and effectiveness. In the warehouse, it must be well ventilated to prevent the accumulation of harmful gases. And it must be placed separately from flammable, explosive and toxic materials, and must not be mixed to avoid danger. When storing, packaging is also crucial. It is necessary to ensure that the packaging is intact and there is no risk of leakage. If the packaging is damaged, immediate measures should be taken to deal with it.
As for transportation, the transportation vehicle must be clean and dry, and no other residues should react with sodium 4-chloro-3-nitrobenzene sulfonate. During transportation, beware of sun and rain exposure, which may damage the goods. During the handling process, the operation must be gentle, not brutal loading and unloading, to avoid packaging collision damage. At the same time, transport personnel need to be familiar with its characteristics and emergency treatment methods, and can respond in time in case of emergencies.
Furthermore, whether it is storage or transportation, relevant places and vehicles should be equipped with corresponding fire and leakage emergency treatment equipment. In case of fire, suitable fire extinguishing materials can be selected according to their nature; if there is a leak, effective measures can be taken quickly to collect and clean up to prevent the spread of pollution. In this way, the safety of sodium 4-chloro-3-nitrobenzene sulfonate during storage and transportation can be guaranteed.
At one end of the environment, it may have multiple effects. If it flows into water bodies, it may cause water pollution due to its certain water solubility. Aquatic organisms live in water bodies containing this substance for a long time, or suffer from many adverse effects. It contains groups such as chlorine, nitro and sulfonate, which may interfere with the normal physiological functions of aquatic organisms. For example, it may affect the respiration, reproduction and larval development of fish, causing changes in population numbers. For soil, if it penetrates into it, or changes the soil physical and chemical properties, it will affect the structure and function of soil microbial communities, pose a threat to the balance of soil ecosystems, and then affect plant growth.
There are also hidden dangers in terms of human health. Inhaled through the respiratory tract, the particles of this substance may irritate the mucosa of the respiratory tract, causing uncomfortable symptoms such as cough and asthma, and long-term exposure or increase the risk of respiratory diseases. If it is exposed to the skin, it is irritating to a certain extent, or it may cause redness, swelling, itching, and even burning of the skin. Accidentally ingested, it will damage the digestive system, such as corroding the mucosa of the mouth, esophagus and stomach, causing severe pain, vomiting and other serious consequences. And the substance contains nitro and chlorine atoms. Some studies suggest that it may be potentially carcinogenic, and the risk of cancer in people exposed to it for a long time may be increased.
In summary, sodium 4-chloro-3-nitrobenzene sulfonate poses a potential hazard to the environment and human health. During the production, use and disposal of this substance, it is necessary to strictly abide by relevant norms and standards, and do a good job of protection and treatment to reduce its adverse effects on the environment and human health.

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