Linshang Chemical
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4-Chloro-3-Nitrobenzenesulfonyl Chloride
Linshang Chemical
|
HS Code |
634326 |
| Chemical Formula | C6H3Cl2NO4S |
| Molecular Weight | 256.06 |
| Appearance | Solid |
| Color | Yellow to orange |
| Odor | Pungent |
| Melting Point | 67 - 71 °C |
| Boiling Point | Decomposes |
| Solubility In Water | Reacts |
| Solubility In Organic Solvents | Soluble in some organic solvents like dichloromethane |
| Density | 1.79 g/cm³ |
As an accredited 4-Chloro-3-Nitrobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 4 - chloro - 3 - nitrobenzenesulfonyl chloride packaged in a sealed glass bottle. |
| Storage | 4 - chloro - 3 - nitrobenzenesulfonyl chloride should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and incompatible substances such as strong bases and reducing agents. Store in a tightly sealed container to prevent contact with moisture, which can cause decomposition. Label containers clearly to ensure proper handling. |
| Shipping | 4 - chloro - 3 - nitrobenzenesulfonyl chloride is a chemical. Ship it in tightly - sealed containers, compliant with hazardous chemical regulations. Ensure proper labeling for safe and regulated transportation. |
Competitive 4-Chloro-3-Nitrobenzenesulfonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Chloro-3-Nitrobenzenesulfonyl Chloride in China?
As a trusted 4-Chloro-3-Nitrobenzenesulfonyl Chloride manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Chloro-3-Nitrobenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4-chloro-3-nitrobenzenesulfonyl Chloride?
4-Chloro-3-nitrobenzenesulfonyl chloride is widely used in various fields of chemical industry.
First, it is often a key intermediate in the synthesis of medicine.
Second, it is also important in the preparation of pesticides. It can be chemically modified to derive compounds with insecticidal, weeding and other properties. The functional groups in its structure can endow the product with the ability to interact with the physiological processes of pests and weeds, or inhibit its key enzyme activities, or interfere with its metabolic pathways, achieving the purpose of preventing and controlling pests and ensuring the robust growth of crops.
Third, it is also useful in the field of materials science. It can participate in the synthesis of polymer materials, and introduce special functional structures into the polymer chain with its active groups. Or enhance the chemical stability of the material, or endow the material with the responsiveness to specific substances, so that the material exhibits unique properties in the fields of electronics and optics, and meets the strict requirements of high-tech materials.
In summary, 4-chloro-3-nitrobenzenesulfonyl chloride, with its unique structure and activity, is an indispensable and important chemical raw material in many fields such as medicine, pesticides and materials science, promoting technological innovation and development in various fields.
First, it is often a key intermediate in the synthesis of medicine.
Second, it is also important in the preparation of pesticides. It can be chemically modified to derive compounds with insecticidal, weeding and other properties. The functional groups in its structure can endow the product with the ability to interact with the physiological processes of pests and weeds, or inhibit its key enzyme activities, or interfere with its metabolic pathways, achieving the purpose of preventing and controlling pests and ensuring the robust growth of crops.
Third, it is also useful in the field of materials science. It can participate in the synthesis of polymer materials, and introduce special functional structures into the polymer chain with its active groups. Or enhance the chemical stability of the material, or endow the material with the responsiveness to specific substances, so that the material exhibits unique properties in the fields of electronics and optics, and meets the strict requirements of high-tech materials.
In summary, 4-chloro-3-nitrobenzenesulfonyl chloride, with its unique structure and activity, is an indispensable and important chemical raw material in many fields such as medicine, pesticides and materials science, promoting technological innovation and development in various fields.
What are the physical properties of 4-chloro-3-nitrobenzenesulfonyl Chloride?
The physical properties of 4-chloro-3-nitrobenzenesulfonyl chloride are particularly important for its many applications. Its appearance is often in the shape of white to light yellow crystalline powder, just like the fine crystals carved by the years, faintly shining under the light.
Looking at its melting point, it is about 44-48 ° C. It is like a critical point. If the temperature changes slightly, its physical state may change. Such melting point characteristics are the key elements for precise control in many chemical processes.
When it comes to solubility, it is soluble in organic solvents such as dichloromethane and chloroform, just like fish entering water and fusing seamlessly. This solubility property allows it to blend with many organic reagents in the field of organic synthesis to form new compounds. However, its solubility in water is very small, and it is as difficult to blend with water as oil and water, which limits its application in aqueous systems.
Furthermore, its density is also a significant physical property. Appropriate density gives it unique sedimentation and stratification properties in mixtures, which become available in the process of separation and purification.
Its low vapor pressure indicates that under normal temperature and pressure, the tendency to volatilize is weak, which adds a boost to safety during storage and transportation.
Such physical properties, or such as melting point, solubility, density, vapor pressure, etc., are intertwined with each other to form the basis for the application of 4-chloro-3-nitrobenzenesulfonyl chloride in many fields such as chemical and pharmaceutical synthesis. It is used by the Fang family to exert its unique effectiveness.
Looking at its melting point, it is about 44-48 ° C. It is like a critical point. If the temperature changes slightly, its physical state may change. Such melting point characteristics are the key elements for precise control in many chemical processes.
When it comes to solubility, it is soluble in organic solvents such as dichloromethane and chloroform, just like fish entering water and fusing seamlessly. This solubility property allows it to blend with many organic reagents in the field of organic synthesis to form new compounds. However, its solubility in water is very small, and it is as difficult to blend with water as oil and water, which limits its application in aqueous systems.
Furthermore, its density is also a significant physical property. Appropriate density gives it unique sedimentation and stratification properties in mixtures, which become available in the process of separation and purification.
Its low vapor pressure indicates that under normal temperature and pressure, the tendency to volatilize is weak, which adds a boost to safety during storage and transportation.
Such physical properties, or such as melting point, solubility, density, vapor pressure, etc., are intertwined with each other to form the basis for the application of 4-chloro-3-nitrobenzenesulfonyl chloride in many fields such as chemical and pharmaceutical synthesis. It is used by the Fang family to exert its unique effectiveness.
What is the chemical synthesis method of 4-chloro-3-nitrobenzenesulfonyl Chloride?
The chemical synthesis of 4-chloro-3-nitrobenzenesulfonyl chloride is a key issue in the field of organic synthesis. Its synthesis route often follows the classical organic reaction mechanism and is transformed through multiple steps.
The first step is often to use benzene as the initial raw material. Benzene is chemically active and can be synthesized by electrophilic substitution reaction. First, benzene and chlorine are substituted to form chlorobenzene. This reaction requires a suitable catalyst, such as ferric chloride, to promote the electrophilic attack of chlorine atoms on the benzene ring to obtain chlorobenzene products.
The second step is to introduce nitro groups on the basis of chlorobenzene. A mixed acid (a mixture of nitric acid and sulfuric acid) can be used, and a nitrification reaction can occur at appropriate temperature and conditions. The introduction of nitro groups requires careful control of the reaction conditions, because the strong electron-withdrawing properties of nitro groups will affect the subsequent reactivity. This step results in 4-chloro-3-nitrobenzene.
Furthermore, the conversion of 4-chloro-3-nitrobenzene to 4-chloro-3-nitrobenzene sulfonyl chloride lies in the sulfonylation reaction. Fuming sulfuric acid or chlorosulfonic acid is generally used as a sulfonation reagent to introduce a sulfonyl group into the benzene ring. After that, the sulfonyl group is converted into sulfonyl chloride by chlorination reagents such as sulfoxide chloride, and the final result is 4-chloro-3-nitrobenzene sulfonyl chloride.
During the synthesis process, each step of the reaction requires precise control of the reaction conditions, such as temperature, reaction time, and proportion of reactants, and attention needs to be paid to the separation and purification of intermediates to ensure the purity and yield of the target product. In this way, 4-chloro-3-nitrobenzenesulfonyl chloride can be effectively synthesized.
The first step is often to use benzene as the initial raw material. Benzene is chemically active and can be synthesized by electrophilic substitution reaction. First, benzene and chlorine are substituted to form chlorobenzene. This reaction requires a suitable catalyst, such as ferric chloride, to promote the electrophilic attack of chlorine atoms on the benzene ring to obtain chlorobenzene products.
The second step is to introduce nitro groups on the basis of chlorobenzene. A mixed acid (a mixture of nitric acid and sulfuric acid) can be used, and a nitrification reaction can occur at appropriate temperature and conditions. The introduction of nitro groups requires careful control of the reaction conditions, because the strong electron-withdrawing properties of nitro groups will affect the subsequent reactivity. This step results in 4-chloro-3-nitrobenzene.
Furthermore, the conversion of 4-chloro-3-nitrobenzene to 4-chloro-3-nitrobenzene sulfonyl chloride lies in the sulfonylation reaction. Fuming sulfuric acid or chlorosulfonic acid is generally used as a sulfonation reagent to introduce a sulfonyl group into the benzene ring. After that, the sulfonyl group is converted into sulfonyl chloride by chlorination reagents such as sulfoxide chloride, and the final result is 4-chloro-3-nitrobenzene sulfonyl chloride.
During the synthesis process, each step of the reaction requires precise control of the reaction conditions, such as temperature, reaction time, and proportion of reactants, and attention needs to be paid to the separation and purification of intermediates to ensure the purity and yield of the target product. In this way, 4-chloro-3-nitrobenzenesulfonyl chloride can be effectively synthesized.
What are the precautions for 4-chloro-3-nitrobenzenesulfonyl Chloride during storage and transportation?
4-Chloro-3-nitrobenzenesulfonyl chloride is also a chemical substance. During storage and transportation, many matters need to be paid attention to.
It is active and easily hydrolyzed in contact with water, so when storing, be sure to ensure that the environment is dry, avoid shady places, away from water sources, moisture and rain. And it must be stored separately from oxidants, alkalis and other substances, and must not be mixed to prevent violent chemical reactions from occurring and causing danger.
During transportation, the packaging must be tight and firm to prevent leakage. The means of transportation must also be clean and dry, and no moisture or other substances that may react with it should be left. Escort personnel should be familiar with its physical and chemical properties and emergency response methods, and guard carefully along the way.
Furthermore, this substance is toxic and corrosive, and is harmful to both the human body and the environment. Whether it is a storage site or a transportation vehicle, it should be equipped with corresponding emergency treatment equipment and protective equipment, such as adsorption materials, neutralizers, protective clothing, gas masks, etc. In the unfortunate event of a leak, emergency measures must be taken immediately, evacuate the surrounding personnel, seal the scene, and properly handle the leak in a professional manner. Do not slack off, so as not to cause personal injury and environmental pollution. Only through thorough preparation and careful operation can the safety of storage and transportation be guaranteed.
It is active and easily hydrolyzed in contact with water, so when storing, be sure to ensure that the environment is dry, avoid shady places, away from water sources, moisture and rain. And it must be stored separately from oxidants, alkalis and other substances, and must not be mixed to prevent violent chemical reactions from occurring and causing danger.
During transportation, the packaging must be tight and firm to prevent leakage. The means of transportation must also be clean and dry, and no moisture or other substances that may react with it should be left. Escort personnel should be familiar with its physical and chemical properties and emergency response methods, and guard carefully along the way.
Furthermore, this substance is toxic and corrosive, and is harmful to both the human body and the environment. Whether it is a storage site or a transportation vehicle, it should be equipped with corresponding emergency treatment equipment and protective equipment, such as adsorption materials, neutralizers, protective clothing, gas masks, etc. In the unfortunate event of a leak, emergency measures must be taken immediately, evacuate the surrounding personnel, seal the scene, and properly handle the leak in a professional manner. Do not slack off, so as not to cause personal injury and environmental pollution. Only through thorough preparation and careful operation can the safety of storage and transportation be guaranteed.
4-chloro-3-nitrobenzenesulfonyl Chloride Effects on the Environment and Human Health
4-Chloro-3-nitrobenzenesulfonyl chloride has a great impact on the environment and human health.
First talk about its harm to the environment. If this substance flows into natural water bodies, it will cause water quality to deteriorate. Because of its chemical toxicity, organisms in the water, from plankton to fish and shrimp aquariums, will be harmed by it. Or disrupt its physiological function, causing its growth and reproduction to be blocked, and even die in large numbers, disrupting the ecological balance of the water body. And because of its stable chemical properties, it is difficult to degrade naturally, and will persist in the environment for a long time, accumulate continuously, and then harm the surrounding soil. Decrease soil fertility, affect plant root uptake of nutrients, cause plant growth and damage terrestrial ecosystems.
As for the impact on human health, it should not be underestimated. If people breathe in the air containing this substance, or come into contact with the skin, it will cause many health problems. It has strong irritation to the skin and mucous membranes. When the skin touches it, it can cause redness, swelling, itching, burning, and even rashes, blisters, and in severe cases, skin ulceration. In the eyes, it can damage the eye tissue, affect vision, and even cause blindness. If inhaled, it will irritate the respiratory tract, causing coughing, asthma, breathing difficulties, etc. Long-term exposure to this environment may increase the risk of respiratory diseases, such as bronchitis, emphysema, etc. Even more terrifying, this substance may be potentially carcinogenic, and long-term exposure will increase the risk of cancer in the human body, endangering life.
Therefore, p-4-chloro-3-nitrobenzenesulfonyl chloride should be handled with caution and its production, use and emissions should be strictly controlled to protect the environment and human health.
First talk about its harm to the environment. If this substance flows into natural water bodies, it will cause water quality to deteriorate. Because of its chemical toxicity, organisms in the water, from plankton to fish and shrimp aquariums, will be harmed by it. Or disrupt its physiological function, causing its growth and reproduction to be blocked, and even die in large numbers, disrupting the ecological balance of the water body. And because of its stable chemical properties, it is difficult to degrade naturally, and will persist in the environment for a long time, accumulate continuously, and then harm the surrounding soil. Decrease soil fertility, affect plant root uptake of nutrients, cause plant growth and damage terrestrial ecosystems.
As for the impact on human health, it should not be underestimated. If people breathe in the air containing this substance, or come into contact with the skin, it will cause many health problems. It has strong irritation to the skin and mucous membranes. When the skin touches it, it can cause redness, swelling, itching, burning, and even rashes, blisters, and in severe cases, skin ulceration. In the eyes, it can damage the eye tissue, affect vision, and even cause blindness. If inhaled, it will irritate the respiratory tract, causing coughing, asthma, breathing difficulties, etc. Long-term exposure to this environment may increase the risk of respiratory diseases, such as bronchitis, emphysema, etc. Even more terrifying, this substance may be potentially carcinogenic, and long-term exposure will increase the risk of cancer in the human body, endangering life.
Therefore, p-4-chloro-3-nitrobenzenesulfonyl chloride should be handled with caution and its production, use and emissions should be strictly controlled to protect the environment and human health.
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