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4-Chloro-Α-(4-Chlorophenyl)-Α-(Trichloromethyl)Benzenemethanol
Linshang Chemical
|
HS Code |
952528 |
| Name | 4-Chloro-α-(4-Chlorophenyl)-α-(Trichloromethyl)Benzenemethanol |
| Chemical Formula | C14H9Cl5O |
| Molar Mass | 371.48 g/mol |
| Appearance | Solid (usually white or off - white) |
| Melting Point | Approximately 105 - 107 °C |
| Solubility In Water | Very low solubility, practically insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Density | Data may vary, but generally in the range of 1.5 - 1.7 g/cm³ |
| Purity | Can be produced in high purity grades, e.g., 95%+ |
| Odor | Odorless or very faint odor |
| Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 4-Chloro-Α-(4-Chlorophenyl)-Α-(Trichloromethyl)Benzenemethanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - chloro - α - (4 - chlorophenyl) - α - (trichloromethyl)benzenemethanol in sealed chemical - grade packaging. |
| Storage | 4 - chloro - α - (4 - chlorophenyl) - α - (trichloromethyl)benzenemethanol should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly closed container to prevent moisture absorption and potential degradation. Avoid storage near incompatible substances to ensure safety and integrity of the chemical. |
| Shipping | 4 - chloro - α - (4 - chlorophenyl) - α - (trichloromethyl)benzenemethanol is shipped in well - sealed, corrosion - resistant containers. It adheres to strict chemical transportation regulations to ensure safe transit, with proper labeling for handling and storage. |
Competitive 4-Chloro-Α-(4-Chlorophenyl)-Α-(Trichloromethyl)Benzenemethanol prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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What are the chemical properties of 4-chloro-alpha - (4-chlorophenyl) -alpha - (trichloromethyl) benzenemethanol
4-Chloro-alpha - (4-chlorophenyl ） -α -（ trichloromethyl) benzyl alcohol, this is an organic compound. Its chemical properties are unique and quite complex.
In terms of physical properties, it may be in a solid state at room temperature, but it also depends on specific environmental factors. The melting point and boiling point of this substance are key physical parameters. The melting point can be determined from the temperature of the transition between solid and liquid states. The boiling point indicates the condition for its liquid to gas state. Unfortunately, I do not know the exact value.
In terms of chemical properties, the compound contains chlorine atoms and benzene ring structures, which give it specific reactivity. Chlorine atoms are active and can participate in various substitution reactions. Under suitable conditions, the chlorine atom may be replaced by other atoms or groups, and this reaction may be caused by the role of nucleophiles in the reaction environment. The benzene ring structure endows it with aromaticity, making it able to participate in electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc.
Furthermore, trichloromethyl is attached to the α-position, and this group has a significant impact on the electron cloud distribution of the compound, which in turn affects its reactivity and chemical properties. Trichloromethyl has strong electron absorption, or reduces the electron cloud density of the benzene ring, causing the electrophilic substitution reaction activity to change.
Its hydroxyl group is also an important reaction check point, which can participate in the esterification reaction and react with organic or inorganic acids to form corresponding esters. At the same time, the hydroxyl group can be oxidized to form different oxidation products such as aldose, ketone or carboxylic acid, and the specific products vary depending on the oxidation conditions.
In addition, the stability of this compound is also concerned. In view of the fact that it contains multiple chlorine atoms, or the decomposition reaction occurs under specific conditions, resulting in structural changes. Light, high temperature, specific catalysts and other factors may promote its decomposition.
In short, 4-chloro-alpha - (4-chlorophenyl ） -α -（ trichloromethyl) benzyl alcohol has rich chemical properties and may have potential application value in organic synthesis, pharmaceutical chemistry and other fields. However, its properties and reaction laws need to be further studied in order to better control and utilize it.
In terms of physical properties, it may be in a solid state at room temperature, but it also depends on specific environmental factors. The melting point and boiling point of this substance are key physical parameters. The melting point can be determined from the temperature of the transition between solid and liquid states. The boiling point indicates the condition for its liquid to gas state. Unfortunately, I do not know the exact value.
In terms of chemical properties, the compound contains chlorine atoms and benzene ring structures, which give it specific reactivity. Chlorine atoms are active and can participate in various substitution reactions. Under suitable conditions, the chlorine atom may be replaced by other atoms or groups, and this reaction may be caused by the role of nucleophiles in the reaction environment. The benzene ring structure endows it with aromaticity, making it able to participate in electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc.
Furthermore, trichloromethyl is attached to the α-position, and this group has a significant impact on the electron cloud distribution of the compound, which in turn affects its reactivity and chemical properties. Trichloromethyl has strong electron absorption, or reduces the electron cloud density of the benzene ring, causing the electrophilic substitution reaction activity to change.
Its hydroxyl group is also an important reaction check point, which can participate in the esterification reaction and react with organic or inorganic acids to form corresponding esters. At the same time, the hydroxyl group can be oxidized to form different oxidation products such as aldose, ketone or carboxylic acid, and the specific products vary depending on the oxidation conditions.
In addition, the stability of this compound is also concerned. In view of the fact that it contains multiple chlorine atoms, or the decomposition reaction occurs under specific conditions, resulting in structural changes. Light, high temperature, specific catalysts and other factors may promote its decomposition.
In short, 4-chloro-alpha - (4-chlorophenyl ） -α -（ trichloromethyl) benzyl alcohol has rich chemical properties and may have potential application value in organic synthesis, pharmaceutical chemistry and other fields. However, its properties and reaction laws need to be further studied in order to better control and utilize it.
What are the physical properties of 4-chloro-alpha - (4-chlorophenyl) -alpha - (trichloromethyl) benzenemethanol
4 - chloro - α - ( 4 - chlorophen yl ) - α - ( trichloromethyl) benzenemethanol, this is an organic compound, its physical properties are particularly important, and it is related to many practical applications.
Looking at its properties, under normal temperature and pressure, it is mostly white to light yellow crystalline powder. This form makes the substance relatively stable and easy to handle when stored and transported, unlike liquid substances that are prone to leakage, and unlike gaseous substances that require special containers to be stored.
The melting point is about 105-110 ° C. The characteristics of the melting point are crucial for the purification and identification of the substance. By measuring the melting point, the purity of the substance can be determined. If the purity is high, the melting point range is relatively narrow; if it contains impurities, the melting point will be reduced and the melting range will be wider.
Furthermore, the substance is insoluble in water. This is due to the existence of groups such as benzene ring and chlorine atom in the molecular structure, which makes its polarity weak, while water is a polar solvent. According to the principle of "similar miscibility", it is insoluble in water. However, it is soluble in some organic solvents, such as dichloromethane, chloroform, acetone, etc. This solubility can be used to select suitable reaction solvents in organic synthesis, so that the reaction can proceed smoothly. When separating and purifying substances, suitable extractants can also be selected according to their characteristics to achieve separation from other impurities.
Its density is about 1.6 g/cm ³. The physical property of density plays an important role in quantitative operations involving the substance, such as preparing solutions and determining the proportion of reactants.
In addition, the chemical properties of this substance are relatively stable at room temperature, but under extreme conditions such as high temperature, strong acid, and strong alkali, chemical reactions such as hydrolysis and substitution may occur, which in turn affect its physical properties.
In summary, the physical properties of 4 - chloro - α - ( 4 - chlorophen yl ) - α - ( trichloromethyl) benzenemethanol, from appearance, melting point, solubility to density, have their own characteristics and uses, which are of great significance for its application in many fields such as chemical industry and medicine.
Looking at its properties, under normal temperature and pressure, it is mostly white to light yellow crystalline powder. This form makes the substance relatively stable and easy to handle when stored and transported, unlike liquid substances that are prone to leakage, and unlike gaseous substances that require special containers to be stored.
The melting point is about 105-110 ° C. The characteristics of the melting point are crucial for the purification and identification of the substance. By measuring the melting point, the purity of the substance can be determined. If the purity is high, the melting point range is relatively narrow; if it contains impurities, the melting point will be reduced and the melting range will be wider.
Furthermore, the substance is insoluble in water. This is due to the existence of groups such as benzene ring and chlorine atom in the molecular structure, which makes its polarity weak, while water is a polar solvent. According to the principle of "similar miscibility", it is insoluble in water. However, it is soluble in some organic solvents, such as dichloromethane, chloroform, acetone, etc. This solubility can be used to select suitable reaction solvents in organic synthesis, so that the reaction can proceed smoothly. When separating and purifying substances, suitable extractants can also be selected according to their characteristics to achieve separation from other impurities.
Its density is about 1.6 g/cm ³. The physical property of density plays an important role in quantitative operations involving the substance, such as preparing solutions and determining the proportion of reactants.
In addition, the chemical properties of this substance are relatively stable at room temperature, but under extreme conditions such as high temperature, strong acid, and strong alkali, chemical reactions such as hydrolysis and substitution may occur, which in turn affect its physical properties.
In summary, the physical properties of 4 - chloro - α - ( 4 - chlorophen yl ) - α - ( trichloromethyl) benzenemethanol, from appearance, melting point, solubility to density, have their own characteristics and uses, which are of great significance for its application in many fields such as chemical industry and medicine.
What is the main use of 4-chloro-alpha - (4-chlorophenyl) -alpha - (trichloromethyl) benzenemethanol
4 - chloro - α - ( 4 - chlorophen yl ) - α - ( trichloromethyl) benzenemethanol is an organic compound with a wide range of main uses. In the field of pesticides, this compound has significant effects. Because of its specific chemical structure and properties, it can be used as a key intermediate in the synthesis of a variety of high-efficiency pesticides. By precisely interfering with the physiological functions of pests, it can achieve the effect of efficient pest killing, thus effectively protecting the growth of crops, reducing the damage of pests to crops, and improving crop yield and quality.
It also has potential application value in the field of pharmaceutical research and development. After in-depth exploration and modification of its chemical structure, researchers hope to develop drugs with unique pharmacological activities. In addition, in the field of organic synthetic chemistry, 4-chloro - α - ( 4-chlorophen yl ) - α - ( trichloromethyl) benzenemethanol is often used as an important starting material or reaction intermediate. Because of its complex and unique structure, it can participate in many complex organic reactions, enabling chemists to construct various novel and complex organic compounds, injecting new impetus into the development of organic synthetic chemistry, and promoting the continuous expansion of this field.
It also has potential application value in the field of pharmaceutical research and development. After in-depth exploration and modification of its chemical structure, researchers hope to develop drugs with unique pharmacological activities. In addition, in the field of organic synthetic chemistry, 4-chloro - α - ( 4-chlorophen yl ) - α - ( trichloromethyl) benzenemethanol is often used as an important starting material or reaction intermediate. Because of its complex and unique structure, it can participate in many complex organic reactions, enabling chemists to construct various novel and complex organic compounds, injecting new impetus into the development of organic synthetic chemistry, and promoting the continuous expansion of this field.
What is the synthesis method of 4-chloro-alpha - (4-chlorophenyl) -alpha - (trichloromethyl) benzenemethanol
To prepare 4-chloro-alpha - (4-chlorophenyl ） -α -（ trichloromethyl) benzyl alcohol, the method is as follows:
First take the appropriate raw materials, starting with 4-chlorobenzaldehyde and trichloromethane. In a clean reactor, add an appropriate amount of catalyst, such as alkali substances, such as potassium hydroxide or sodium hydroxide alcohol solution. The reactor is closed, the temperature is controlled within a certain range, and the temperature is slowly warmed to a suitable temperature, usually between 40 and 60 degrees Celsius, so that 4-chlorobenzaldehyde and trichloromethane undergo nucleophilic addition reaction. During this reaction, the carbon anion of trichloromethane conducts a nucleophilic attack on the carbonyl carbon of 4-chlorobenzaldehyde to form an intermediate product.
After the reaction is completed, the reaction mixture is extracted with an appropriate organic solvent, such as ether or dichloromethane, to separate the organic phase. The organic phase is then washed with water several times to remove the salts and unreacted bases, and then washed with saturated saline water to reduce the water content in the organic phase.
After washing, the organic phase is dried. Anhydrous sodium sulfate or anhydrous magnesium sulfate can be selected and left to stand for a period of time to allow the desiccant to absorb the water. Then the desiccant is filtered to remove the desiccant to obtain a dry organic phase.
Finally, the organic solvent is removed by vacuum distillation to obtain the crude product. Then the crude product is recrystallized, a suitable solvent is selected, such as a mixed solvent of ethanol and water, the temperature is properly controlled and the proportion of the solvent is adjusted. After multiple crystallization, filtration and drying, the pure 4-chloro-α - (4-chlorophenyl ） -α -（ trichloromethyl) benzyl alcohol is finally obtained. In this way, it is a common way to synthesize this compound.
First take the appropriate raw materials, starting with 4-chlorobenzaldehyde and trichloromethane. In a clean reactor, add an appropriate amount of catalyst, such as alkali substances, such as potassium hydroxide or sodium hydroxide alcohol solution. The reactor is closed, the temperature is controlled within a certain range, and the temperature is slowly warmed to a suitable temperature, usually between 40 and 60 degrees Celsius, so that 4-chlorobenzaldehyde and trichloromethane undergo nucleophilic addition reaction. During this reaction, the carbon anion of trichloromethane conducts a nucleophilic attack on the carbonyl carbon of 4-chlorobenzaldehyde to form an intermediate product.
After the reaction is completed, the reaction mixture is extracted with an appropriate organic solvent, such as ether or dichloromethane, to separate the organic phase. The organic phase is then washed with water several times to remove the salts and unreacted bases, and then washed with saturated saline water to reduce the water content in the organic phase.
After washing, the organic phase is dried. Anhydrous sodium sulfate or anhydrous magnesium sulfate can be selected and left to stand for a period of time to allow the desiccant to absorb the water. Then the desiccant is filtered to remove the desiccant to obtain a dry organic phase.
Finally, the organic solvent is removed by vacuum distillation to obtain the crude product. Then the crude product is recrystallized, a suitable solvent is selected, such as a mixed solvent of ethanol and water, the temperature is properly controlled and the proportion of the solvent is adjusted. After multiple crystallization, filtration and drying, the pure 4-chloro-α - (4-chlorophenyl ） -α -（ trichloromethyl) benzyl alcohol is finally obtained. In this way, it is a common way to synthesize this compound.
What are the precautions for the use of 4-chloro-alpha - (4-chlorophenyl) -alpha - (trichloromethyl) benzenemethanol
4-Chloro - α -（ 4-chlorophenyl ） - α -（ trichloromethyl) benzyl alcohol, when used, many matters cannot be ignored.
First, this substance is toxic and must not be ignored. Users should strictly follow safety procedures, such as when handling, must wear protective equipment, gloves, masks, protective clothing, etc., all of which are indispensable to prevent it from contact with the skin and eyes. If you accidentally touch it, rinse it with plenty of water quickly, and seek medical attention urgently.
Second, this substance also has an impact on the environment. Waste after use cannot be disposed of at will, and must be properly disposed of in accordance with relevant regulations to avoid polluting the environment. Because it may persist in the environment for a long time, it is tired of water, soil, harm and organisms.
Third, be careful when storing. It should be placed in a cool, dry and ventilated place, protected from fire and heat, and separated from oxidants, acids and other substances to prevent reactions and cause danger. The storage place should be clearly marked to show its characteristics and hazards.
Fourth, when using, the dosage should be precisely controlled. According to the needs of experiment or production, according to scientific methods, accurately measure, do not overdose, to avoid adverse consequences. And when using, pay close attention to the reaction situation, if there is any abnormality, take measures quickly.
Fifth, the relevant operators must undergo professional training and be familiar with the nature, use, harm and countermeasures of this object. Untrained people are not allowed to operate without authorization to avoid disasters.
First, this substance is toxic and must not be ignored. Users should strictly follow safety procedures, such as when handling, must wear protective equipment, gloves, masks, protective clothing, etc., all of which are indispensable to prevent it from contact with the skin and eyes. If you accidentally touch it, rinse it with plenty of water quickly, and seek medical attention urgently.
Second, this substance also has an impact on the environment. Waste after use cannot be disposed of at will, and must be properly disposed of in accordance with relevant regulations to avoid polluting the environment. Because it may persist in the environment for a long time, it is tired of water, soil, harm and organisms.
Third, be careful when storing. It should be placed in a cool, dry and ventilated place, protected from fire and heat, and separated from oxidants, acids and other substances to prevent reactions and cause danger. The storage place should be clearly marked to show its characteristics and hazards.
Fourth, when using, the dosage should be precisely controlled. According to the needs of experiment or production, according to scientific methods, accurately measure, do not overdose, to avoid adverse consequences. And when using, pay close attention to the reaction situation, if there is any abnormality, take measures quickly.
Fifth, the relevant operators must undergo professional training and be familiar with the nature, use, harm and countermeasures of this object. Untrained people are not allowed to operate without authorization to avoid disasters.
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