Linshang Chemical
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4-Chloro-Benzenesulfonicacichloride
Linshang Chemical
|
HS Code |
881692 |
| Chemical Formula | C6H4Cl2O2S |
| Molar Mass | 211.065 g/mol |
| Appearance | Colorless to light - yellow liquid |
| Boiling Point | ~250 - 255 °C |
| Density | Approx. 1.48 - 1.52 g/cm³ |
| Solubility In Water | Reacts with water |
| Solubility In Organic Solvents | Soluble in many organic solvents like dichloromethane, toluene |
| Flash Point | High, relatively non - flammable |
| Irritancy | Corrosive and irritant to skin, eyes, and respiratory tract |
As an accredited 4-Chloro-Benzenesulfonicacichloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 4 - chloro - benzenesulfonic acid chloride packaged in a sealed chemical - resistant container. |
| Storage | 4 - Chloro - benzenesulfonic acid chloride should be stored in a cool, dry, well - ventilated area away from heat sources and ignition points. It should be kept in a tightly - sealed container to prevent contact with moisture, which can cause hydrolysis. Store it separately from incompatible substances like bases, water - reactive materials, and reducing agents to avoid potential chemical reactions. |
| Shipping | 4 - chloro - benzenesulfonic acid chloride should be shipped in tightly - sealed, corrosion - resistant containers. It must be transported under regulated conditions, following safety protocols due to its chemical nature, avoiding exposure to moisture and incompatible substances. |
Competitive 4-Chloro-Benzenesulfonicacichloride prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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What is the chemistry of 4-chloro-benzenesulfonicacichloride?
4-Chloro-benzenesulfonyl chloride has unique chemical properties and strong reactivity.
This substance contains chlorine atoms and sulfonyl chloride groups. The sulfonyl chloride base is active and easy to hydrolyze. It reacts with water to form 4-chloro-benzenesulfonate and hydrogen chloride. This hydrolysis reaction is violent and often releases heat. The chemical equation is as follows: $C_ {6} H_ {4} ClSO_ {2} Cl + H_ {2} O\ longrightarrow C_ {6} H_ {4} ClSO_ {3} H + HCl $.
4-chloro-benzenesulfonyl chloride also reacts easily with alcohols. After the substitution process, 4-chloro-benzenesulfonate and hydrogen chloride are formed. For example, by reacting with ethanol, 4-chloro-benzenesulfonate ethyl ester can be obtained. The reaction formula is: $C_ {6} H_ {4} ClSO_ {2} Cl + C_ {2} H_ {5} OH\ longrightarrow C_ {6} H_ {4} ClSO_ {3} C_ {2} H_ {5} + HCl $. When
reacts with amines, the chlorine atom in the sulfonyl chloride group is replaced by an amine group to form a sulfonamide compound. Taking the reaction with methylamine as an example, the product is N-methyl-4-chloro-benzenesulfonamide, and the reaction equation is: $C_ {6} H_ {4} ClSO_ {2} Cl + CH_ {3} NH_ {2}\ longrightarrow C_ {6} H_ {4} ClSO_ {2} NHCH_ {3} + HCl $.
In the field of organic synthesis, 4-chloro-benzenesulfonyl chloride is widely used. It can be used as an important intermediate for the preparation of a variety of drugs, dyes and pesticides. Due to its active chemical properties, the above reactions can be used to introduce sulfonyl groups and other functional groups to construct specific structures and properties for target compounds. For example, when synthesizing certain antimicrobial active drugs, it is used to react with amino-containing compounds to generate key sulfonamide structures, which endow the drugs with antibacterial properties.
This substance contains chlorine atoms and sulfonyl chloride groups. The sulfonyl chloride base is active and easy to hydrolyze. It reacts with water to form 4-chloro-benzenesulfonate and hydrogen chloride. This hydrolysis reaction is violent and often releases heat. The chemical equation is as follows: $C_ {6} H_ {4} ClSO_ {2} Cl + H_ {2} O\ longrightarrow C_ {6} H_ {4} ClSO_ {3} H + HCl $.
4-chloro-benzenesulfonyl chloride also reacts easily with alcohols. After the substitution process, 4-chloro-benzenesulfonate and hydrogen chloride are formed. For example, by reacting with ethanol, 4-chloro-benzenesulfonate ethyl ester can be obtained. The reaction formula is: $C_ {6} H_ {4} ClSO_ {2} Cl + C_ {2} H_ {5} OH\ longrightarrow C_ {6} H_ {4} ClSO_ {3} C_ {2} H_ {5} + HCl $. When
reacts with amines, the chlorine atom in the sulfonyl chloride group is replaced by an amine group to form a sulfonamide compound. Taking the reaction with methylamine as an example, the product is N-methyl-4-chloro-benzenesulfonamide, and the reaction equation is: $C_ {6} H_ {4} ClSO_ {2} Cl + CH_ {3} NH_ {2}\ longrightarrow C_ {6} H_ {4} ClSO_ {2} NHCH_ {3} + HCl $.
In the field of organic synthesis, 4-chloro-benzenesulfonyl chloride is widely used. It can be used as an important intermediate for the preparation of a variety of drugs, dyes and pesticides. Due to its active chemical properties, the above reactions can be used to introduce sulfonyl groups and other functional groups to construct specific structures and properties for target compounds. For example, when synthesizing certain antimicrobial active drugs, it is used to react with amino-containing compounds to generate key sulfonamide structures, which endow the drugs with antibacterial properties.
What are the common uses of 4-chloro-benzenesulfonicacichloride?
4-Chlorobenzenesulfonyl chloride is an important raw material for organic synthesis. It has a wide range of common uses and has important applications in many fields.
First, in the process of drug synthesis, 4-chlorobenzenesulfonyl chloride is often a key intermediate. For example, when preparing some antibacterial and anti-inflammatory drugs, with its special chemical structure, it can participate in multi-step reactions to build a specific structure of drug molecules and endow drugs with corresponding biological activities. The combination of phenyl ring, chlorine atom and sulfonyl chloride group makes the compound have unique reactivity and selectivity, and can precisely connect to the reaction check point required for drug synthesis.
Second, in the dye industry, 4-chlorobenzenesulfonyl chloride is also indispensable. It can be used to react with various aromatic amines or phenolic compounds to produce dyes with bright color and good stability. The introduced sulfonyl chloride group can enhance the binding force of dyes and fibers and other substrates, making the dyeing effect firmer and longer lasting.
Furthermore, in the field of pesticide synthesis, 4-chlorobenzenesulfonyl chloride is often an important starting material for the creation of new pesticides. By chemically modifying it and introducing different substituents, pesticide products with high insecticidal, bactericidal or herbicidal activities can be prepared. The modifiability of its structure provides a broad space for the design and optimization of pesticide molecules.
In addition, in the field of materials science, 4-chlorobenzenesulfonyl chloride can participate in the synthesis of polymers. It reacts with monomers containing active hydrogen to form polymer materials with special properties, such as improving the heat resistance and chemical corrosion resistance of materials, so as to meet the specific requirements of different industrial scenarios for material properties.
In summary, 4-chlorobenzenesulfonyl chloride plays a crucial role in many industrial fields such as medicine, dyes, pesticides and materials due to its unique chemical properties, providing an indispensable material basis for the development of various industries.
First, in the process of drug synthesis, 4-chlorobenzenesulfonyl chloride is often a key intermediate. For example, when preparing some antibacterial and anti-inflammatory drugs, with its special chemical structure, it can participate in multi-step reactions to build a specific structure of drug molecules and endow drugs with corresponding biological activities. The combination of phenyl ring, chlorine atom and sulfonyl chloride group makes the compound have unique reactivity and selectivity, and can precisely connect to the reaction check point required for drug synthesis.
Second, in the dye industry, 4-chlorobenzenesulfonyl chloride is also indispensable. It can be used to react with various aromatic amines or phenolic compounds to produce dyes with bright color and good stability. The introduced sulfonyl chloride group can enhance the binding force of dyes and fibers and other substrates, making the dyeing effect firmer and longer lasting.
Furthermore, in the field of pesticide synthesis, 4-chlorobenzenesulfonyl chloride is often an important starting material for the creation of new pesticides. By chemically modifying it and introducing different substituents, pesticide products with high insecticidal, bactericidal or herbicidal activities can be prepared. The modifiability of its structure provides a broad space for the design and optimization of pesticide molecules.
In addition, in the field of materials science, 4-chlorobenzenesulfonyl chloride can participate in the synthesis of polymers. It reacts with monomers containing active hydrogen to form polymer materials with special properties, such as improving the heat resistance and chemical corrosion resistance of materials, so as to meet the specific requirements of different industrial scenarios for material properties.
In summary, 4-chlorobenzenesulfonyl chloride plays a crucial role in many industrial fields such as medicine, dyes, pesticides and materials due to its unique chemical properties, providing an indispensable material basis for the development of various industries.
What is the preparation method of 4-chloro-benzenesulfonicacichloride?
There is an ancient way to prepare 4-chlorobenzenesulfonyl chloride. In the past, to make this substance, first take chlorobenzene as the starting material, pour it slowly into the kettle containing fuming sulfuric acid. At this time, the temperature needs to be carefully controlled so that the temperature in the kettle is stable in a suitable environment, probably in a certain temperature range, to prevent side reactions from clumping. When chlorobenzene meets fuming sulfuric acid, it is sulfonated into 4-chlorobenzenesulfonic acid.
When 4-chlorobenzenesulfonic acid is obtained, then take it, put it into another kettle, and add sulfoxide chloride. The two meet and respond. Sulfoxide chloride, in this case, is a chlorination agent, which can convert the sulfonic acid group of 4-chlorobenzenesulfonic acid into a sulfonyl chloride group. When appropriate, it is also necessary to pay attention to temperature control and stirring to ensure that it should be uniform and fast. After the completion of the kettle, by distillation, fractional distillation, etc. to remove its impurities, pure 4-chlorobenzenesulfonyl chloride can be obtained.
Another method is to use benzene as the initial material and chlorinate it to obtain chlorobenzene. As before, 4-chlorobenzenesulfonic acid is obtained by combining chlorobenzene with nicotinic sulfuric acid, and 4-chlorobenzenesulfonic acid is mixed with thion All these methods require workers to abide by the procedures and strictly control the factors such as oil temperature and material ratio in order to obtain good 4-chlorobenzenesulfonyl chloride.
When 4-chlorobenzenesulfonic acid is obtained, then take it, put it into another kettle, and add sulfoxide chloride. The two meet and respond. Sulfoxide chloride, in this case, is a chlorination agent, which can convert the sulfonic acid group of 4-chlorobenzenesulfonic acid into a sulfonyl chloride group. When appropriate, it is also necessary to pay attention to temperature control and stirring to ensure that it should be uniform and fast. After the completion of the kettle, by distillation, fractional distillation, etc. to remove its impurities, pure 4-chlorobenzenesulfonyl chloride can be obtained.
Another method is to use benzene as the initial material and chlorinate it to obtain chlorobenzene. As before, 4-chlorobenzenesulfonic acid is obtained by combining chlorobenzene with nicotinic sulfuric acid, and 4-chlorobenzenesulfonic acid is mixed with thion All these methods require workers to abide by the procedures and strictly control the factors such as oil temperature and material ratio in order to obtain good 4-chlorobenzenesulfonyl chloride.
What are the precautions in storage and transportation of 4-chloro-benzenesulfonicacichloride?
4-Chlorobenzenesulfonyl chloride is a chemical substance, and many things should be paid attention to when storing and transporting.
The first priority is safety, because it is highly corrosive and irritating, and can cause burns when touching the human body. Therefore, when handling, be sure to wear complete protective equipment, such as protective clothing, protective gloves, protective glasses and gas masks, to prevent inadvertent contact.
Storage environment is also crucial. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because it is easy to decompose when heated, harmful gases are produced. It must be stored separately from oxidants, alkalis, etc., and must not be mixed to prevent dangerous chemical reactions.
During transportation, ensure that the container is well sealed and there is no risk of leakage. Select suitable transportation vehicles and packaging materials and follow relevant transportation regulations. When transporting, be careful to avoid collision and vibration to prevent damage to the container.
In addition, it is also necessary to pay attention to its storage period. It should be checked regularly. If any changes in properties or packaging damage are found, it needs to be dealt with in time.
In short, the storage and transportation of 4-chlorobenzenesulfonyl chloride must strictly follow safety regulations and operating procedures to ensure the safety of personnel and the environment is not endangered.
The first priority is safety, because it is highly corrosive and irritating, and can cause burns when touching the human body. Therefore, when handling, be sure to wear complete protective equipment, such as protective clothing, protective gloves, protective glasses and gas masks, to prevent inadvertent contact.
Storage environment is also crucial. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because it is easy to decompose when heated, harmful gases are produced. It must be stored separately from oxidants, alkalis, etc., and must not be mixed to prevent dangerous chemical reactions.
During transportation, ensure that the container is well sealed and there is no risk of leakage. Select suitable transportation vehicles and packaging materials and follow relevant transportation regulations. When transporting, be careful to avoid collision and vibration to prevent damage to the container.
In addition, it is also necessary to pay attention to its storage period. It should be checked regularly. If any changes in properties or packaging damage are found, it needs to be dealt with in time.
In short, the storage and transportation of 4-chlorobenzenesulfonyl chloride must strictly follow safety regulations and operating procedures to ensure the safety of personnel and the environment is not endangered.
4-chloro-benzenesulfonicacichloride impact on the environment and human health
4-Chloro-benzenesulfonyl chloride is a chemical substance. It has an impact on both the environment and human health.
First talk about its impact on the environment. If this substance is released in nature and enters the soil, it may change the chemical properties of the soil, cause soil fertility to decrease, and affect plant growth. In water bodies, it will poison aquatic organisms, disrupt the balance of aquatic ecosystems, threaten the survival of fish, plankton, etc., or cause species to decrease. And because of its chemical stability, it is difficult to degrade, easy to remain for a long time, and accumulates in the environment, causing endless damage.
Again discuss its harm to human health. If people inhale the gas containing this substance, it will irritate the respiratory tract, causing cough, asthma, breathing difficulties and other diseases. Staying in this environment for a long time may damage lung function and increase the risk of respiratory diseases. Contact with the skin can cause redness, swelling, pain, burns, and in severe cases, skin ulceration, which is difficult to heal. If ingested inadvertently, it will damage the digestive system, cause vomiting, abdominal pain, diarrhea, etc., and even endanger life.
Therefore, when using and disposing of 4-chloro-benzenesulfonyl chloride, it is necessary to be cautious and follow strict regulations to prevent it from causing disaster to the environment and human health.
First talk about its impact on the environment. If this substance is released in nature and enters the soil, it may change the chemical properties of the soil, cause soil fertility to decrease, and affect plant growth. In water bodies, it will poison aquatic organisms, disrupt the balance of aquatic ecosystems, threaten the survival of fish, plankton, etc., or cause species to decrease. And because of its chemical stability, it is difficult to degrade, easy to remain for a long time, and accumulates in the environment, causing endless damage.
Again discuss its harm to human health. If people inhale the gas containing this substance, it will irritate the respiratory tract, causing cough, asthma, breathing difficulties and other diseases. Staying in this environment for a long time may damage lung function and increase the risk of respiratory diseases. Contact with the skin can cause redness, swelling, pain, burns, and in severe cases, skin ulceration, which is difficult to heal. If ingested inadvertently, it will damage the digestive system, cause vomiting, abdominal pain, diarrhea, etc., and even endanger life.
Therefore, when using and disposing of 4-chloro-benzenesulfonyl chloride, it is necessary to be cautious and follow strict regulations to prevent it from causing disaster to the environment and human health.
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