Linshang Chemical
PRODUCTS
4-Chloro-N-(2-Chloro-4-Nitrophenyl)-3-(Trifluoromethyl)Benzeneslfonamide
Linshang Chemical
|
HS Code |
496683 |
| Chemical Formula | C13H6Cl2F3N2O4S |
| Molecular Weight | 417.16 g/mol |
| Appearance | Solid (usually powder) |
| Color | May vary, often off - white to yellowish |
| Odor | Typically has a characteristic chemical odor |
| Melting Point | Data may vary depending on purity, around [X] °C |
| Solubility In Water | Low solubility in water |
| Solubility In Organic Solvents | Soluble in some organic solvents like dichloromethane, chloroform |
| Pka | Data may be needed from relevant literature for accurate value |
| Stability | Stable under normal conditions, but may react with strong oxidizing or reducing agents |
| Hazard Class | May be classified as a hazardous chemical, details depend on regulations |
As an accredited 4-Chloro-N-(2-Chloro-4-Nitrophenyl)-3-(Trifluoromethyl)Benzeneslfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 4 - chloro - N - (2 - chloro - 4 - nitrophenyl)-3 - (trifluoromethyl)benzenesulfonamide in sealed container. |
| Storage | Store 4 - chloro - N - (2 - chloro - 4 - nitrophenyl)-3 - (trifluoromethyl)benzenesulfonamide in a cool, dry place away from direct sunlight. Keep it in a well - ventilated area, isolated from incompatible substances like strong oxidizers, acids, and bases. Use tightly - sealed containers to prevent moisture absorption and potential degradation. |
| Shipping | 4 - chloro - N - (2 - chloro - 4 - nitrophenyl)-3 - (trifluoromethyl)benzenesulfonamide is shipped in specialized, sealed containers to prevent leakage. It follows strict hazardous chemical shipping regulations, ensuring safe transit. |
Competitive 4-Chloro-N-(2-Chloro-4-Nitrophenyl)-3-(Trifluoromethyl)Benzeneslfonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Chloro-N-(2-Chloro-4-Nitrophenyl)-3-(Trifluoromethyl)Benzeneslfonamide in China?
As a trusted 4-Chloro-N-(2-Chloro-4-Nitrophenyl)-3-(Trifluoromethyl)Benzeneslfonamide manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Chloro-N-(2-Chloro-4-Nitrophenyl)-3-(Trifluoromethyl)Benzeneslfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 4-chloro-n- (2-chloro-4-nitrophenyl) -3- (trifluoromethyl) benzeneslfonamide
This is the chemical structure analysis of 4-chloro-N- (2-chloro-4-nitrophenyl) -3 - (trifluoromethyl) benzenesulfonamide. According to its name, this compound is derived from the main structure of benzenesulfonamide. In benzenesulfonamide, one end of the sulfonyl group (-SO -2 NH -) is attached to the benzene ring. At the interposition (3-position) of the benzene ring, there is trifluoromethyl (-CF ²). This group has strong electron absorption and can affect the electron cloud distribution and physicochemical properties of the molecule.
In the para-position of the benzene ring (4-position), there is a chlorine atom (-Cl). Furthermore, the phenyl group attached to the nitrogen atom (N) also has a chlorine atom at the 2-position, and a nitro group (-NO 2) at the 4-position. The nitro group also has a strong electron-absorbing effect, which can significantly affect the reactivity and electronic properties of this compound.
Overall, the interaction of the substituents in this chemical structure makes the compound have unique chemical properties. It is a chemical structure worthy of in-depth investigation in the fields of organic synthesis, pharmaceutical chemistry, etc.
In the para-position of the benzene ring (4-position), there is a chlorine atom (-Cl). Furthermore, the phenyl group attached to the nitrogen atom (N) also has a chlorine atom at the 2-position, and a nitro group (-NO 2) at the 4-position. The nitro group also has a strong electron-absorbing effect, which can significantly affect the reactivity and electronic properties of this compound.
Overall, the interaction of the substituents in this chemical structure makes the compound have unique chemical properties. It is a chemical structure worthy of in-depth investigation in the fields of organic synthesis, pharmaceutical chemistry, etc.
What are the physical properties of 4-chloro-n- (2-chloro-4-nitrophenyl) -3- (trifluoromethyl) benzeneslfonamide
4-Chloro-N- (2-chloro-4-nitrophenyl) -3 - (trifluoromethyl) benzenesulfonamide, this is an organic compound. Its physical properties are unique and of great significance for chemical research and industrial applications.
When it comes to appearance, this compound is often in a solid state, mostly white or off-white powdery substance, with fine particles and a relatively uniform feel. This form is conducive to storage and transportation. In many chemical operations, the powder is also easy to accurately weigh and mix.
Its melting point characteristics are remarkable. After rigorous measurement, the melting point is in a specific temperature range. Melting point is a key physical property of a compound, which can help to identify its purity. If impurities are mixed in, the melting point often changes, or decreases, or the melting range becomes wider. The melting point of this compound is stable, reflecting its high purity and relatively stable structure.
In terms of solubility, it shows different solubility characteristics in common organic solvents. In some organic solvents, such as dichloromethane and chloroform, it has good solubility and can quickly dissolve to form a uniform solution. In water, the solubility is extremely low. This difference in solubility is crucial for the separation, purification and solvent selection of compounds. Taking advantage of the difference in solubility in different solvents, an effective separation scheme can be designed to precisely obtain the target product from the reaction mixture.
Furthermore, its density is also an important physical parameter. Although the specific value needs to be determined by accurate experiments, the density characteristics determine its position and distribution in the mixed system. When it comes to operations such as stratification and extraction, the density data provides a key basis for the selection of operating conditions.
In addition, the stability of this compound is worthy of attention. Under conventional conditions, its properties are relatively stable and it is not easy to react with oxygen and moisture in the air. However, under specific conditions, such as high temperature, strong acid and alkali environment, the stability may be affected, and the structure changes, triggering chemical reactions. Therefore, when storing and using, environmental factors need to be considered to ensure that its physical and chemical properties are stable, so as to achieve the expected use effect. The physical properties of 4-chloro-N- (2-chloro-4-nitrophenyl) -3 - (trifluoromethyl) benzenesulfonamide are rich and unique, and they are related to each other. They play a key role in many fields of chemical research and industrial production.
When it comes to appearance, this compound is often in a solid state, mostly white or off-white powdery substance, with fine particles and a relatively uniform feel. This form is conducive to storage and transportation. In many chemical operations, the powder is also easy to accurately weigh and mix.
Its melting point characteristics are remarkable. After rigorous measurement, the melting point is in a specific temperature range. Melting point is a key physical property of a compound, which can help to identify its purity. If impurities are mixed in, the melting point often changes, or decreases, or the melting range becomes wider. The melting point of this compound is stable, reflecting its high purity and relatively stable structure.
In terms of solubility, it shows different solubility characteristics in common organic solvents. In some organic solvents, such as dichloromethane and chloroform, it has good solubility and can quickly dissolve to form a uniform solution. In water, the solubility is extremely low. This difference in solubility is crucial for the separation, purification and solvent selection of compounds. Taking advantage of the difference in solubility in different solvents, an effective separation scheme can be designed to precisely obtain the target product from the reaction mixture.
Furthermore, its density is also an important physical parameter. Although the specific value needs to be determined by accurate experiments, the density characteristics determine its position and distribution in the mixed system. When it comes to operations such as stratification and extraction, the density data provides a key basis for the selection of operating conditions.
In addition, the stability of this compound is worthy of attention. Under conventional conditions, its properties are relatively stable and it is not easy to react with oxygen and moisture in the air. However, under specific conditions, such as high temperature, strong acid and alkali environment, the stability may be affected, and the structure changes, triggering chemical reactions. Therefore, when storing and using, environmental factors need to be considered to ensure that its physical and chemical properties are stable, so as to achieve the expected use effect. The physical properties of 4-chloro-N- (2-chloro-4-nitrophenyl) -3 - (trifluoromethyl) benzenesulfonamide are rich and unique, and they are related to each other. They play a key role in many fields of chemical research and industrial production.
What is the main use of 4-chloro-n- (2-chloro-4-nitrophenyl) -3- (trifluoromethyl) benzeneslfonamide
4-Chloro-N- (2-chloro-4-nitrophenyl) -3 - (trifluoromethyl) benzenesulfonamide has a wide range of main uses. In the field of medicine, it is often a key raw material for the development of new antibacterial and anti-inflammatory drugs. Due to its unique chemical structure and activity, it can effectively interfere with the biochemical reaction process between bacteria and inflammation, and help to develop innovative drugs with high efficiency and low toxicity.
In the field of agriculture, it may be an important component in the preparation of special pesticides. It can target specific pests or diseases and achieve control through precise action mechanisms. Compared with traditional pesticides, it may be more environmentally friendly and reduce the negative impact on the ecological environment.
In the field of materials science, it can be used as a special functional additive. Added to some polymer materials, it may endow materials with excellent properties such as corrosion resistance and wear resistance, broaden material application scenarios, and improve material performance and quality.
In addition, in the field of chemical synthesis, as a key intermediate, through various chemical reactions, many organic compounds with complex structures and specific functions can be derived, laying the foundation for the diversified development of chemical products and promoting continuous innovation and progress in the chemical industry.
In the field of agriculture, it may be an important component in the preparation of special pesticides. It can target specific pests or diseases and achieve control through precise action mechanisms. Compared with traditional pesticides, it may be more environmentally friendly and reduce the negative impact on the ecological environment.
In the field of materials science, it can be used as a special functional additive. Added to some polymer materials, it may endow materials with excellent properties such as corrosion resistance and wear resistance, broaden material application scenarios, and improve material performance and quality.
In addition, in the field of chemical synthesis, as a key intermediate, through various chemical reactions, many organic compounds with complex structures and specific functions can be derived, laying the foundation for the diversified development of chemical products and promoting continuous innovation and progress in the chemical industry.
What is the synthesis method of 4-chloro-n- (2-chloro-4-nitrophenyl) -3- (trifluoromethyl) benzeneslfonamide
The synthesis of 4-chloro-N- (2-chloro-4-nitrophenyl) -3 - (trifluoromethyl) benzenesulfonamide is an important topic in organic synthetic chemistry. The synthesis of this compound often follows a specific organic reaction path and strategy.
The initial step is often to use a suitable benzene derivative as the starting material. For example, the selection of benzene containing a specific substituent can be precisely introduced into the chlorine atom through halogenation reaction. Under suitable reaction conditions, such as the selection of suitable halogenating reagents, such as chlorine gas, sulfoxide chloride, etc., under the catalysis of catalysts such as iron salts or Lewis acids, the specific position of the benzene ring is halogenated to obtain chlorine-containing benzene derivatives.
Then, for the introduction of nitro groups, the nitration reaction is mostly used. The mixed acid system of nitric acid and sulfuric acid is used as the nitration reagent, and the parameters such as reaction temperature, time and ratio of reactants are regulated to precisely locate the nitro group to the desired position of the benzene ring, and the benzene derivative containing chlorine and nitro is obtained. In this step, the control of the reaction conditions is extremely critical. Excessive temperature can easily lead to the formation of polynitrate products, which affects the purity and yield of the target product.
Furthermore, the introduction of trifluoromethyl generally uses specific trifluoromethylating reagents, such as trifluoromethyl halides and trifluoromethylsulfonates. With the help of metal catalysis or nucleophilic substitution and other reaction mechanisms, trifluoromethylates are successfully integrated into the benzene ring. This process requires the selection of suitable catalysts and reaction solvents to ensure the high efficiency and selectivity of the reaction.
Finally, the sulfonamide structure is constructed. First, through the sulfonation reaction, the sulfonic acid group is introduced into the benzene ring. The commonly used sulfonation reagents include concentrated sulfuric acid, fuming sulfuric acid, etc. Then, the resulting sulfonic acid and the amino-containing compound, namely 2-chloro-4-nitroaniline, are amidated by a condensing agent such as dicyclohexyl carbodiimide (DCC), and finally 4-chloro-N - (2-chloro-4-nitrophenyl) -3- (trifluoromethyl) benzenesulfonamide is synthesized. After each step of the reaction, separation and purification methods such as column chromatography and recrystallization are required to ensure the purity of the intermediate product and the final product, thereby improving the efficiency and quality of the entire synthesis process.
The initial step is often to use a suitable benzene derivative as the starting material. For example, the selection of benzene containing a specific substituent can be precisely introduced into the chlorine atom through halogenation reaction. Under suitable reaction conditions, such as the selection of suitable halogenating reagents, such as chlorine gas, sulfoxide chloride, etc., under the catalysis of catalysts such as iron salts or Lewis acids, the specific position of the benzene ring is halogenated to obtain chlorine-containing benzene derivatives.
Then, for the introduction of nitro groups, the nitration reaction is mostly used. The mixed acid system of nitric acid and sulfuric acid is used as the nitration reagent, and the parameters such as reaction temperature, time and ratio of reactants are regulated to precisely locate the nitro group to the desired position of the benzene ring, and the benzene derivative containing chlorine and nitro is obtained. In this step, the control of the reaction conditions is extremely critical. Excessive temperature can easily lead to the formation of polynitrate products, which affects the purity and yield of the target product.
Furthermore, the introduction of trifluoromethyl generally uses specific trifluoromethylating reagents, such as trifluoromethyl halides and trifluoromethylsulfonates. With the help of metal catalysis or nucleophilic substitution and other reaction mechanisms, trifluoromethylates are successfully integrated into the benzene ring. This process requires the selection of suitable catalysts and reaction solvents to ensure the high efficiency and selectivity of the reaction.
Finally, the sulfonamide structure is constructed. First, through the sulfonation reaction, the sulfonic acid group is introduced into the benzene ring. The commonly used sulfonation reagents include concentrated sulfuric acid, fuming sulfuric acid, etc. Then, the resulting sulfonic acid and the amino-containing compound, namely 2-chloro-4-nitroaniline, are amidated by a condensing agent such as dicyclohexyl carbodiimide (DCC), and finally 4-chloro-N - (2-chloro-4-nitrophenyl) -3- (trifluoromethyl) benzenesulfonamide is synthesized. After each step of the reaction, separation and purification methods such as column chromatography and recrystallization are required to ensure the purity of the intermediate product and the final product, thereby improving the efficiency and quality of the entire synthesis process.
What are the precautions for 4-chloro-n- (2-chloro-4-nitrophenyl) -3- (trifluoromethyl) benzeneslfonamide during use?
4-Chloro-N - (2-chloro-4-nitrophenyl) - 3 - (trifluoromethyl) benzenesulfonamide, this is a fine chemical, and many matters need to be paid attention to during use.
Bear the brunt, and safety protection must be comprehensive. Because of its certain toxicity and irritation, protective equipment is indispensable during contact. When operating, wear protective clothing to ensure that the body is not exposed; wear protective gloves to prevent skin contact, because it may be absorbed through the skin, endangering health; goggles are also essential to avoid splashing into the eyes and causing damage to the eyes. In case of inadvertent contact, rinse with plenty of water immediately, and seek medical attention as soon as possible in severe cases.
Furthermore, storage conditions are crucial. Store in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its heat or exposure to open flames, there may be a risk of combustion or explosion. At the same time, it should be stored separately from oxidants, acids, alkalis, etc. to prevent chemical reactions from occurring, resulting in deterioration or danger.
During use, precise control of the dosage is the key. The dosage should be strictly controlled according to specific needs and reaction conditions. Excessive use will not only cause waste, increase costs, but also cause side reactions and affect product quality. When operating, it should be carried out in the fume hood to ensure that the harmful gases generated are discharged in time and reduce the harm to the operator.
In addition, after use, properly dispose of the remaining products and waste should not be underestimated. It must not be discarded at will. It should follow the relevant regulations and carry out harmless treatment to prevent environmental pollution. For the container containing the chemical, it should also be properly disposed of to ensure that no residual chemicals flow out, causing environmental pollution or safety hazards.
In conclusion, when using 4-chloro-N- (2-chloro-4-nitrophenyl) -3- (trifluoromethyl) benzenesulfonamide, safety protection, storage conditions, dosage control, and waste disposal should not be ignored, so as to ensure safe operation and avoid accidents.
Bear the brunt, and safety protection must be comprehensive. Because of its certain toxicity and irritation, protective equipment is indispensable during contact. When operating, wear protective clothing to ensure that the body is not exposed; wear protective gloves to prevent skin contact, because it may be absorbed through the skin, endangering health; goggles are also essential to avoid splashing into the eyes and causing damage to the eyes. In case of inadvertent contact, rinse with plenty of water immediately, and seek medical attention as soon as possible in severe cases.
Furthermore, storage conditions are crucial. Store in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its heat or exposure to open flames, there may be a risk of combustion or explosion. At the same time, it should be stored separately from oxidants, acids, alkalis, etc. to prevent chemical reactions from occurring, resulting in deterioration or danger.
During use, precise control of the dosage is the key. The dosage should be strictly controlled according to specific needs and reaction conditions. Excessive use will not only cause waste, increase costs, but also cause side reactions and affect product quality. When operating, it should be carried out in the fume hood to ensure that the harmful gases generated are discharged in time and reduce the harm to the operator.
In addition, after use, properly dispose of the remaining products and waste should not be underestimated. It must not be discarded at will. It should follow the relevant regulations and carry out harmless treatment to prevent environmental pollution. For the container containing the chemical, it should also be properly disposed of to ensure that no residual chemicals flow out, causing environmental pollution or safety hazards.
In conclusion, when using 4-chloro-N- (2-chloro-4-nitrophenyl) -3- (trifluoromethyl) benzenesulfonamide, safety protection, storage conditions, dosage control, and waste disposal should not be ignored, so as to ensure safe operation and avoid accidents.
Scan to WhatsApp
