Linshang Chemical
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4-Chloro-N,N-Dimethyl-3-Nitrobenzenesulfonamide
Linshang Chemical
|
HS Code |
417745 |
| Chemical Formula | C8H9ClN2O5S |
| Molecular Weight | 280.69 |
| Appearance | Solid (usually) |
| Odor | Typical organic chemical odor |
| Melting Point | Data - specific value needed from literature |
| Boiling Point | Data - specific value needed from literature |
| Solubility In Water | Low (organic compound, generally hydrophobic) |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone |
| Density | Data - specific value needed from literature |
| Flash Point | Data - specific value needed from literature |
| Stability | Stable under normal conditions, but may react with strong oxidizing agents |
| Pka | Data - specific value needed from literature |
As an accredited 4-Chloro-N,N-Dimethyl-3-Nitrobenzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 4 - chloro - N,N - dimethyl - 3 - nitrobenzenesulfonamide in sealed chemical - grade bags. |
| Storage | 4 - chloro - N,N - dimethyl - 3 - nitrobenzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances such as strong oxidizers and reducing agents. Store in a tightly - sealed container to prevent moisture absorption and potential reactions. This helps maintain its chemical stability and safety. |
| Shipping | 4 - chloro - N,N - dimethyl - 3 - nitrobenzenesulfonamide is shipped in accordance with strict chemical regulations. Packaged securely in appropriate containers, transported by carriers compliant with hazardous material shipping rules to ensure safety during transit. |
Competitive 4-Chloro-N,N-Dimethyl-3-Nitrobenzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
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What are the chemical properties of 4-chloro-n, n-dimethyl-3-nitrobenzenesulfonamide
4-Chloro-N, N-dimethyl-3-nitrobenzenesulfonamide, this is an organic compound. Its unique properties and diverse chemical characteristics.
Looking at its structure, the substitution of chlorine atoms, nitro groups and dimethyl groups gives the substance a specific chemical activity. Nitro groups, strong electron-absorbing groups also reduce the electron cloud density of the benzene ring, weaken the electrophilic substitution reaction activity of the benzene ring, but make the electron cloud density of the ortho and para-site more uneven, affecting the selectivity of the reaction check point.
The chemical stability of the substance is acceptable, but it also reacts under specific conditions. For example, under the action of a strong reducing agent, the nitro group may be reduced to an amino group, which is often used in organic synthesis to produce amino-containing compounds.
Because of its sulfonamide structure, it has a certain hydrophilicity and can form hydrogen bonds with water molecules, which affects its solubility. In polar organic solvents, the solubility may be better than that of non-polar solvents.
Under acid-base conditions, the compound may exhibit different chemical behaviors. In an acidic environment, the sulfonamide group is relatively stable; under alkaline conditions, or hydrolysis, the structure changes and the corresponding sulfonic acid and amine products are formed.
In addition, its chlorine atom activity cannot be underestimated. In the presence of appropriate nucleophiles, nucleophilic substitution reactions can occur, and chlorine atoms are replaced by other groups, providing a structural modification pathway for organic synthesis.
In short, the chemical properties of 4-chloro-N, N-dimethyl-3-nitrobenzenesulfonamide are determined by the interaction of various groups in its structure, and have potential application value in the field of organic synthesis and chemistry research.
Looking at its structure, the substitution of chlorine atoms, nitro groups and dimethyl groups gives the substance a specific chemical activity. Nitro groups, strong electron-absorbing groups also reduce the electron cloud density of the benzene ring, weaken the electrophilic substitution reaction activity of the benzene ring, but make the electron cloud density of the ortho and para-site more uneven, affecting the selectivity of the reaction check point.
The chemical stability of the substance is acceptable, but it also reacts under specific conditions. For example, under the action of a strong reducing agent, the nitro group may be reduced to an amino group, which is often used in organic synthesis to produce amino-containing compounds.
Because of its sulfonamide structure, it has a certain hydrophilicity and can form hydrogen bonds with water molecules, which affects its solubility. In polar organic solvents, the solubility may be better than that of non-polar solvents.
Under acid-base conditions, the compound may exhibit different chemical behaviors. In an acidic environment, the sulfonamide group is relatively stable; under alkaline conditions, or hydrolysis, the structure changes and the corresponding sulfonic acid and amine products are formed.
In addition, its chlorine atom activity cannot be underestimated. In the presence of appropriate nucleophiles, nucleophilic substitution reactions can occur, and chlorine atoms are replaced by other groups, providing a structural modification pathway for organic synthesis.
In short, the chemical properties of 4-chloro-N, N-dimethyl-3-nitrobenzenesulfonamide are determined by the interaction of various groups in its structure, and have potential application value in the field of organic synthesis and chemistry research.
What are the main uses of 4-chloro-n, n-dimethyl-3-nitrobenzenesulfonamide
4-Chloro-N, N-dimethyl-3-nitrobenzenesulfonamide, this is an organic compound. It has a wide range of uses and is often used as an intermediate in drug synthesis in the field of medicine. Due to the special chemical structure of this compound, it can introduce specific functional groups to drug molecules, and drugs with specific pharmacological activities can be constructed by chemical synthesis.
It also has important functions in the creation of pesticides. It can derive pesticide ingredients with insecticidal, bactericidal or herbicidal activities, contributing to agricultural pest control and weed control. Its structure can be modified and modified to adapt to different pest control needs and improve the pertinence and effect of pesticides.
also has potential applications in the field of materials science. Or can participate in the synthesis of special materials, giving materials such as special electrical, optical or mechanical properties. For example, or can be used to synthesize functional materials with specific electrical conductivity or optical response to expand the application field of materials.
Because of its active chemical properties, it is often used as a reaction substrate in the field of organic synthetic chemistry, participating in many organic reactions, such as nucleophilic substitution, reduction reactions, etc., to synthesize more complex organic compounds and promote the development of organic synthetic chemistry.
It also has important functions in the creation of pesticides. It can derive pesticide ingredients with insecticidal, bactericidal or herbicidal activities, contributing to agricultural pest control and weed control. Its structure can be modified and modified to adapt to different pest control needs and improve the pertinence and effect of pesticides.
also has potential applications in the field of materials science. Or can participate in the synthesis of special materials, giving materials such as special electrical, optical or mechanical properties. For example, or can be used to synthesize functional materials with specific electrical conductivity or optical response to expand the application field of materials.
Because of its active chemical properties, it is often used as a reaction substrate in the field of organic synthetic chemistry, participating in many organic reactions, such as nucleophilic substitution, reduction reactions, etc., to synthesize more complex organic compounds and promote the development of organic synthetic chemistry.
What is the synthesis method of 4-chloro-n, n-dimethyl-3-nitrobenzenesulfonamide
To prepare 4-chloro-N, N-dimethyl-3-nitrobenzenesulfonamide, the method is as follows:
First take an appropriate amount of 3-nitro-4-chlorobenzenesulfonyl chloride as the starting material. This compound is highly active and is often a key starting material in organic synthesis reactions. Place it in a clean and dry reaction vessel with a good seal and stirring device to ensure that the reaction proceeds uniformly.
Add dimethylamine slowly. The amount of dimethylamine must be accurately calculated, generally slightly more than 3-nitro-4-chlorobenzenesulfonyl chloride, to promote the reaction to move in the direction of generating the target product. When adding dimethylamine, it is necessary to pay close attention to the reaction temperature. Because the reaction is an exothermic reaction, the temperature is easy to rise suddenly. If it is not properly controlled, it may cause side reactions to occur, which will affect the purity and yield of the product. Therefore, a low temperature bath is often used to maintain the temperature of the reaction system in a suitable range, generally between 0 ° C and 10 ° C. During the
reaction, the sulfonyl chloride group of 3-nitro-4-chlorobenzenesulfonyl chloride and the amino group of dimethylamine undergo nucleophilic substitution. The nitrogen atom of dimethylamine is rich in electrons and has strong nucleophilicity. It attacks the sulfur atom of the sulfonyl chloride group. The chlorine atom leaves, and then forms a C-N bond to obtain 4-chloro-N, N-dimethyl-3-nitrobenzenesulfonamide.
After the reaction is completed, the product mixture may contain unreacted raw materials, by-products and solvents. A series of separation and purification steps are required. First, the product is extracted with a suitable organic solvent, and the product is transferred to the organic phase to separate from the aqueous impurities. Then the organic phase is washed with a dilute acid and a dilute alkali solution to remove the remaining alkaline or acidic impurities. Then the organic phase is dried with a desiccant such as anhydrous sodium sulfate Finally, the organic solvent is removed by reduced pressure distillation to obtain the crude product.
The crude product needs to be further purified, and recrystallization is often used. Select a suitable solvent, which needs to have a high solubility of the product at high temperature and a low solubility at low temperature. After recrystallization operation, high purity 4-chloro-N, N-dimethyl-3-nitrobenzenesulfonamide can be obtained. In this way, a pure target product can be obtained.
First take an appropriate amount of 3-nitro-4-chlorobenzenesulfonyl chloride as the starting material. This compound is highly active and is often a key starting material in organic synthesis reactions. Place it in a clean and dry reaction vessel with a good seal and stirring device to ensure that the reaction proceeds uniformly.
Add dimethylamine slowly. The amount of dimethylamine must be accurately calculated, generally slightly more than 3-nitro-4-chlorobenzenesulfonyl chloride, to promote the reaction to move in the direction of generating the target product. When adding dimethylamine, it is necessary to pay close attention to the reaction temperature. Because the reaction is an exothermic reaction, the temperature is easy to rise suddenly. If it is not properly controlled, it may cause side reactions to occur, which will affect the purity and yield of the product. Therefore, a low temperature bath is often used to maintain the temperature of the reaction system in a suitable range, generally between 0 ° C and 10 ° C. During the
reaction, the sulfonyl chloride group of 3-nitro-4-chlorobenzenesulfonyl chloride and the amino group of dimethylamine undergo nucleophilic substitution. The nitrogen atom of dimethylamine is rich in electrons and has strong nucleophilicity. It attacks the sulfur atom of the sulfonyl chloride group. The chlorine atom leaves, and then forms a C-N bond to obtain 4-chloro-N, N-dimethyl-3-nitrobenzenesulfonamide.
After the reaction is completed, the product mixture may contain unreacted raw materials, by-products and solvents. A series of separation and purification steps are required. First, the product is extracted with a suitable organic solvent, and the product is transferred to the organic phase to separate from the aqueous impurities. Then the organic phase is washed with a dilute acid and a dilute alkali solution to remove the remaining alkaline or acidic impurities. Then the organic phase is dried with a desiccant such as anhydrous sodium sulfate Finally, the organic solvent is removed by reduced pressure distillation to obtain the crude product.
The crude product needs to be further purified, and recrystallization is often used. Select a suitable solvent, which needs to have a high solubility of the product at high temperature and a low solubility at low temperature. After recrystallization operation, high purity 4-chloro-N, N-dimethyl-3-nitrobenzenesulfonamide can be obtained. In this way, a pure target product can be obtained.
What are the physical properties of 4-chloro-n, n-dimethyl-3-nitrobenzenesulfonamide
4-Chloro-N, N-dimethyl-3-nitrobenzenesulfonamide is one of the organic compounds. Its physical properties are crucial and related to many practical applications.
First of all, its appearance is often white to light yellow crystalline powder, which is easy to observe and handle. The appearance is delicate, and the touch is also characteristic. It is gently twisted in the hand, like fine particles.
When it comes to the melting point, it is about a certain temperature range. This melting point is an important basis for determining its purity and stability. If the purity is high, the melting point is relatively stable and accurate; if it contains impurities, the melting point may be deviated.
The solubility cannot be ignored. In common organic solvents, such as ethanol, acetone, etc., there is a certain solubility. In ethanol, after stirring, it is partially soluble to form a slightly cloudy or clear solution. However, in water, the solubility is poor, and it mostly exists in the form of precipitation at the bottom of the water. This difference in solubility has a great impact on the separation, purification and selection of chemical reaction solvents.
Furthermore, its density is also fixed. Although the value is not often concerned by everyone, in chemical production, when it involves material ratio, container carrying capacity calculation and other links, density is an indispensable parameter.
In addition, in terms of odor, it has a weak special odor, non-pungent and unpleasant smell, but it may be detectable when exposed to it for a long time in a confined space.
In summary, the physical properties of 4-chloro-N, N-dimethyl-3-nitrobenzenesulfonamide are all factors that need to be carefully considered in the R & D and production processes of chemical and pharmaceutical fields, and play a crucial role in their related applications.
First of all, its appearance is often white to light yellow crystalline powder, which is easy to observe and handle. The appearance is delicate, and the touch is also characteristic. It is gently twisted in the hand, like fine particles.
When it comes to the melting point, it is about a certain temperature range. This melting point is an important basis for determining its purity and stability. If the purity is high, the melting point is relatively stable and accurate; if it contains impurities, the melting point may be deviated.
The solubility cannot be ignored. In common organic solvents, such as ethanol, acetone, etc., there is a certain solubility. In ethanol, after stirring, it is partially soluble to form a slightly cloudy or clear solution. However, in water, the solubility is poor, and it mostly exists in the form of precipitation at the bottom of the water. This difference in solubility has a great impact on the separation, purification and selection of chemical reaction solvents.
Furthermore, its density is also fixed. Although the value is not often concerned by everyone, in chemical production, when it involves material ratio, container carrying capacity calculation and other links, density is an indispensable parameter.
In addition, in terms of odor, it has a weak special odor, non-pungent and unpleasant smell, but it may be detectable when exposed to it for a long time in a confined space.
In summary, the physical properties of 4-chloro-N, N-dimethyl-3-nitrobenzenesulfonamide are all factors that need to be carefully considered in the R & D and production processes of chemical and pharmaceutical fields, and play a crucial role in their related applications.
4-Chloro-n, n-dimethyl-3-nitrobenzenesulfonamide what are the precautions during use
4-Chloro-N, N-dimethyl-3-nitrobenzenesulfonamide, when used, many matters must not be ignored.
The first priority is safety. This material may be toxic and irritating, and can be harmful if it touches the skin, enters the eyes or inhales its dust and vapor. When operating, it is necessary to wear suitable protective equipment, such as gloves, goggles, gas masks, etc., and use it in a well-ventilated place to prevent the accumulation of harmful substances and endanger the person.
The second is storage. When stored in a cool, dry and ventilated place, away from fire and heat sources, it should also be stored separately from oxidants, alkalis, etc., and must not be mixed with storage, otherwise it may cause chemical reactions and cause danger.
Furthermore, when taking it, accurate measurement is the key. According to the required dosage, take it with an appropriate measuring tool to avoid waste, and prevent improper dosage from causing subsequent reactions to fail to meet expectations. And the operation should be slow, handle it with care to prevent it from spilling. If there is any spilling, clean it immediately according to the specifications to prevent environmental pollution.
During use, the reaction conditions need to be strictly controlled. Factors such as temperature, pH, reaction time, etc. can all affect the reaction process and products. Therefore, before the experiment or production, it is advisable to study the relevant data in detail, predict the test conditions, and closely observe the reaction phenomenon during operation, and adjust it at any time.
At the end, after use, properly dispose of the residue and waste. It should not be dumped at will. It should be collected and treated in accordance with relevant regulations and environmental protection requirements to ensure that it does not cause pollution to the environment.
In short, with 4-chloro-N, N-dimethyl-3-nitrobenzenesulfonamide, everything must be treated with caution to ensure safety and promote effect.
The first priority is safety. This material may be toxic and irritating, and can be harmful if it touches the skin, enters the eyes or inhales its dust and vapor. When operating, it is necessary to wear suitable protective equipment, such as gloves, goggles, gas masks, etc., and use it in a well-ventilated place to prevent the accumulation of harmful substances and endanger the person.
The second is storage. When stored in a cool, dry and ventilated place, away from fire and heat sources, it should also be stored separately from oxidants, alkalis, etc., and must not be mixed with storage, otherwise it may cause chemical reactions and cause danger.
Furthermore, when taking it, accurate measurement is the key. According to the required dosage, take it with an appropriate measuring tool to avoid waste, and prevent improper dosage from causing subsequent reactions to fail to meet expectations. And the operation should be slow, handle it with care to prevent it from spilling. If there is any spilling, clean it immediately according to the specifications to prevent environmental pollution.
During use, the reaction conditions need to be strictly controlled. Factors such as temperature, pH, reaction time, etc. can all affect the reaction process and products. Therefore, before the experiment or production, it is advisable to study the relevant data in detail, predict the test conditions, and closely observe the reaction phenomenon during operation, and adjust it at any time.
At the end, after use, properly dispose of the residue and waste. It should not be dumped at will. It should be collected and treated in accordance with relevant regulations and environmental protection requirements to ensure that it does not cause pollution to the environment.
In short, with 4-chloro-N, N-dimethyl-3-nitrobenzenesulfonamide, everything must be treated with caution to ensure safety and promote effect.
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