4-Chlorobenzene-1,3-Diamine

Linshang Chemical

Specifications

HS Code

410954

Chemical Formula C6H7ClN2
Molar Mass 142.59 g/mol
Appearance Solid
Color White to off - white
Odor Characteristic amine - like odor
Melting Point 117 - 120 °C
Boiling Point 292 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in ethanol, ether
Flash Point 165 °C
Pka For the two amino groups, pKa values are in the range of typical aromatic amines (around 4 - 5 for the conjugate acid of the first amino group and slightly lower for the second)

As an accredited 4-Chlorobenzene-1,3-Diamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 4 - chlorobenzene - 1,3 - diamine packaged in air - tight plastic bags.
Storage 4 - chlorobenzene - 1,3 - diamine should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly closed container to prevent moisture and air exposure, which could lead to chemical reactions. Store it separately from oxidizing agents, acids, and other incompatible substances to avoid potential hazards.
Shipping 4 - Chlorobenzene - 1,3 - diamine is shipped in sealed, corrosion - resistant containers. Shipment follows strict hazardous chemical regulations, ensuring proper labeling, secure packaging to prevent leaks during transit.
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4-Chlorobenzene-1,3-Diamine 4-Chlorobenzene-1,3-Diamine
General Information
Where to Buy 4-Chlorobenzene-1,3-Diamine in China?
As a trusted 4-Chlorobenzene-1,3-Diamine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Chlorobenzene-1,3-Diamine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-chlorobenzene-1,3-diamine?
4-Chloroquine-1,3-diamine is a class of organic compounds with a unique chemical structure. Its main uses are quite extensive, and it plays a key role in the field of medicine, especially in the development of antimalarial drugs.
Malaria has always been a global disease that seriously threatens human health and poses a great challenge to human life safety. In the past, the rampage of malaria parasites has caused countless people to suffer from diseases. The special chemical properties of 4-chloroquine-1,3-diamine can effectively interfere with the metabolic process and reproduction path of malaria parasites in human red blood cells. It can specifically combine with certain key proteins or nucleic acids in the malaria parasite, thereby inhibiting the growth, development and reproduction of the malaria parasite, and ultimately achieving the purpose of fighting malaria.
With the continuous progress and development of medical science, researchers have conducted in-depth research on 4-chloroquine-1,3-diamine. In addition to antimalarial, they are also exploring its potential application value in the treatment of other diseases. Some studies have shown that it may have a certain immunomodulatory effect in the treatment of some autoimmune diseases, such as rheumatoid arthritis, which is expected to open up a new path for the treatment of such diseases. However, this is still in the exploratory stage of research, and more experimental and clinical validation is needed to determine its exact efficacy and safety.
What are the physical properties of 4-chlorobenzene-1,3-diamine?
4-Chloronaphthalene-1,3-diphenol is an organic compound with the following physical properties:
Viewed, it is often in a crystalline solid state, which is easy to store and manipulate. The color is almost white to light yellow, and the color is bright.
Smell, 4-chloronaphthalene-1,3-diphenol emits a unique odor. Although the odor intensity or concentration varies, it is characteristic and can be used as an important marker when identifying this substance.
When talking about the melting point, it is about [specific value] ℃. This property is useful for identification and purification. Its purity can be determined by melting point measurement.
In terms of solubility, it is slightly soluble in water, but easily soluble in many organic solvents, such as ethanol, ether, acetone, etc. This difference in solubility is due to the polar and non-polar parts of the molecular structure. During the chemical synthesis and separation process, an appropriate solvent can be selected according to this characteristic to achieve the purpose of dissolution, reaction or separation.
In addition, 4-chloronaphthalene-1,3-diphenol has a density of [specific value] g/cm ³, and the relative density is a specific value, so that it can be separated under specific conditions due to density differences in the mixture. And because it is a solid, compared with gases and liquids, the intermolecular arrangement is more closely ordered, which makes its physical properties unique and requires consideration in practical applications and research.
Is 4-chlorobenzene-1,3-diamine chemically stable?
The chemical properties of 4-bromo-1,3-diethylbenzene are still stable. In this compound, the benzene ring structure endows it with certain stability. Although the bromine atom has certain activity, it is conjugated with the benzene ring, and the electron cloud distribution is dispersed, making it difficult to break the carbon-bromine bond.
The alkyl side chain of 1,3-diethylbenzene is also difficult to react under normal conditions. The capped alkyl group is relatively stable and requires specific reaction conditions, such as high temperature, light or the presence of a specific catalyst.
Furthermore, the bond energy distribution between the atoms in the molecule of this compound is relatively balanced, and there is no activity check point that is extremely vulnerable to attack. In order to make it react, more severe conditions are often required, such as strong oxidizing agents, strong acids or strong bases, and the reaction can only occur under suitable temperature and pressure.
Overall, 4-bromo-1,3-diethylbenzene is chemically stable at room temperature and pressure and in conventional environments, and it is not easy to spontaneously produce significant chemical changes. However, under specific conditions in chemical production and laboratories, it can still participate in various organic synthesis reactions under suitable reaction conditions to prepare the required compounds.
What are the precautions for 4-chlorobenzene-1,3-diamine in the production process?
There are many precautions in the production process of 4-bromo-1,3-dibenzene.
First, the selection of raw materials must be cautious. The purity of bromine needs to reach a high standard, if impurities exist, or cause reaction deviation, it will affect the purity and yield of the product. 1,3-dibenzene should also be strictly screened to ensure quality, otherwise the reaction will be complicated and the amount of impurities produced will increase.
Second, precise control of the reaction conditions is extremely critical. In terms of temperature, this reaction is extremely sensitive to temperature. If the temperature is too high, side reactions will occur frequently, and the selectivity of the product will decrease. If the temperature is too low, the reaction rate will be slow and time-consuming. The pressure cannot be ignored. The appropriate pressure can help the reaction to proceed forward and ensure the reaction efficiency and product quality. The use of catalysts also needs to be accurate. An appropriate amount of catalysts can greatly increase the reaction rate. However, improper dosage may cause the reaction to go out of control.
Third, the reaction equipment needs to be adapted. The material should be able to resist the corrosion of chemicals such as bromine, otherwise the equipment will be damaged, which will not only shorten the life, but also may cause safety accidents. And the equipment must be well sealed. Bromine is volatile and toxic, and leakage will endanger the safety of personnel and the environment.
Fourth, safety protection measures are essential. Operators must be fully armed. Protective clothing, gloves, and protective masks are readily available to avoid contact and inhalation of bromine and related chemicals with the body. The ventilation facilities in the workshop should be improved to discharge harmful gases in time. At the same time, the reaction waste should be properly disposed of and should not be discarded at will
Fifth, quality monitoring runs through the whole process. Real-time monitoring during the reaction can detect abnormalities in time and adjust reaction parameters. After the product is generated, strictly test the purity and other indicators. If it does not meet the standard, it is strictly forbidden to flow into the next link.
What is the market price range for 4-chlorobenzene-1,3-diamine?
4-Deuterated naphthalene-1,3-dialdehyde is an important intermediate commonly used in organic synthesis. Its market price range varies depending on changes in quality, purity and market supply and demand.
Generally speaking, if it is ordinary purity, the price per gram may be around a few hundred yuan in market transactions. However, if the purity is extremely high, reaching the scientific research level, and the impurity content is strictly controlled, the price will rise sharply, or more than 1,000 yuan per gram.
The reason for this is that because the preparation of high-purity products requires more complicated and delicate processes, the requirements for production equipment and technicians are also higher, and the purification process loses a lot, so the cost increases sharply, and the price is also high. For ordinary purity, the preparation process is relatively simple, the cost is controllable, and the price is relatively close to the people.
In the chemical raw material market, many production enterprises and scientific research institutions have a lot of demand for this material, but the market supply is also relatively sufficient. Therefore, its price is roughly within the above range, but it will still fluctuate slightly with the economic situation, fluctuations in raw material prices and other factors.