Linshang Chemical
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4-Chlorobenzenecarbothioamide
Linshang Chemical
|
HS Code |
638971 |
| Name | 4-Chlorobenzenecarbothioamide |
| Molecular Formula | C7H6ClNS |
| Molar Mass | 171.65 g/mol |
| Appearance | Off - white to light yellow solid |
| Melting Point | 167 - 171 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone |
| Odor | Characteristic sulfur - containing odor |
| Chemical Class | Thioamide |
| Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 4-Chlorobenzenecarbothioamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - chlorobenzenecarbothioamide packaged in a sealed, chemical - resistant bag. |
| Storage | 4 - chlorobenzenecarbothioamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent moisture absorption and potential reactions. It's crucial to store it separately from incompatible substances to avoid dangerous chemical interactions. |
| Shipping | 4 - chlorobenzenecarbothioamide is shipped in well - sealed, corrosion - resistant containers. They are carefully packaged to prevent leakage during transit, following strict chemical shipping regulations to ensure safety. |
Competitive 4-Chlorobenzenecarbothioamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Chlorobenzenecarbothioamide in China?
As a trusted 4-Chlorobenzenecarbothioamide manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Chlorobenzenecarbothioamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4-chlorobenzenecarbothioamide?
4-Chlorobenzolamide, an organic compound, is useful in many fields.
First, in the field of medicinal chemistry, it is an important synthesis intermediate. Drug developers use this to build molecular structures with specific biological activities. Take some antidepressant drugs as an example. During the synthesis process, 4-chlorobenzolamide can undergo a series of chemical reactions and connect with other chemical groups to shape drug molecules that fit human targets, helping it modulate neurotransmitters and relieve depression symptoms.
Second, in the field of materials science, it may participate in the synthesis of functional materials. For example, when preparing some materials with special optical or electrical properties, 4-chlorobenzolamide can impart unique properties to the material due to its unique chemical structure. For example, a specific photoelectric conversion material, after adding this substance, it can optimize its light absorption and charge transport ability, and improve the photoelectric properties of the material.
Furthermore, in organic synthetic chemistry, it is a key building block. Chemists use its chemical activity to build complex organic molecular structures through various reactions, such as nucleophilic substitution and addition. After ingeniously designing the reaction route, 4-chlorobenzolamide can be used as the starting material to prepare organic compounds with diverse structures, which can contribute to the development of organic synthetic chemistry.
First, in the field of medicinal chemistry, it is an important synthesis intermediate. Drug developers use this to build molecular structures with specific biological activities. Take some antidepressant drugs as an example. During the synthesis process, 4-chlorobenzolamide can undergo a series of chemical reactions and connect with other chemical groups to shape drug molecules that fit human targets, helping it modulate neurotransmitters and relieve depression symptoms.
Second, in the field of materials science, it may participate in the synthesis of functional materials. For example, when preparing some materials with special optical or electrical properties, 4-chlorobenzolamide can impart unique properties to the material due to its unique chemical structure. For example, a specific photoelectric conversion material, after adding this substance, it can optimize its light absorption and charge transport ability, and improve the photoelectric properties of the material.
Furthermore, in organic synthetic chemistry, it is a key building block. Chemists use its chemical activity to build complex organic molecular structures through various reactions, such as nucleophilic substitution and addition. After ingeniously designing the reaction route, 4-chlorobenzolamide can be used as the starting material to prepare organic compounds with diverse structures, which can contribute to the development of organic synthetic chemistry.
What are the physical properties of 4-chlorobenzenecarbothioamide?
4-chlorobenzenecarbothioamide, that is, 4-chlorobenzolamide, is an organic compound. Its physical properties are as follows:
Looking at it, it is mostly solid at room temperature, and the color is white to light yellow crystalline powder. This appearance is easy to store and transport, and it is also easy to handle in chemical production operations.
Smell, has a special smell. Although this smell is not strong and pungent, it has a unique logo, which can help professionals to identify by smell in the experimental or production environment.
When it comes to melting point, it is about 150 - 155 ° C. The melting point is the inherent property of the substance. At this temperature, the solid 4-chlorobenzolamide is endothermally converted into a liquid state. This property is crucial in the purification and identification of compounds, and its purity can be judged by melting point measurement.
In terms of solubility, it is slightly soluble in water. Water is a common solvent, and its slight solubility in water means that the interaction with water molecules is weak. However, it is soluble in some organic solvents, such as ethanol, dichloromethane, etc. This property makes it possible to choose a suitable organic solvent to dissolve in the organic synthesis reaction and promote the reaction.
In addition, the density of 4-chlorobenzolamide is about 1.4 g/cm ³, and the density reflects the mass per unit volume of the substance. This parameter is quite important when designing packaging for storage and transportation, considering its space occupation and weight distribution.
The above physical properties are of great significance for the synthesis, separation, storage and application of 4-chlorobenzolamide, and provide a basic basis for related work in the fields of chemical industry and medicine.
Looking at it, it is mostly solid at room temperature, and the color is white to light yellow crystalline powder. This appearance is easy to store and transport, and it is also easy to handle in chemical production operations.
Smell, has a special smell. Although this smell is not strong and pungent, it has a unique logo, which can help professionals to identify by smell in the experimental or production environment.
When it comes to melting point, it is about 150 - 155 ° C. The melting point is the inherent property of the substance. At this temperature, the solid 4-chlorobenzolamide is endothermally converted into a liquid state. This property is crucial in the purification and identification of compounds, and its purity can be judged by melting point measurement.
In terms of solubility, it is slightly soluble in water. Water is a common solvent, and its slight solubility in water means that the interaction with water molecules is weak. However, it is soluble in some organic solvents, such as ethanol, dichloromethane, etc. This property makes it possible to choose a suitable organic solvent to dissolve in the organic synthesis reaction and promote the reaction.
In addition, the density of 4-chlorobenzolamide is about 1.4 g/cm ³, and the density reflects the mass per unit volume of the substance. This parameter is quite important when designing packaging for storage and transportation, considering its space occupation and weight distribution.
The above physical properties are of great significance for the synthesis, separation, storage and application of 4-chlorobenzolamide, and provide a basic basis for related work in the fields of chemical industry and medicine.
What are the chemical properties of 4-chlorobenzenecarbothioamide?
4-chlorobenzenecarbothioamide, Chinese name 4-chlorobenzolamide, is a member of the family of organic compounds. Its physical and chemical properties are unique and play an important role in many chemical processes and related fields.
In terms of physical properties, 4-chlorobenzolamide is often in solid form. The color of this compound is usually white to off-white crystalline powder, which is fine and uniform, and has a pure appearance, which facilitates its application in many experimental and industrial processes. Its melting point is also a key physical parameter. Generally, it is in a specific temperature range, about 170-175 ° C. The melting point characteristic is of great significance in the separation, purification and identification of compounds. In addition, its solubility characteristics are also worthy of attention. In common organic solvents, such as ethanol and acetone, it exhibits a certain solubility and can be moderately dissolved to form a homogeneous solution; in water, its solubility is poor and only slightly soluble. This property is closely related to the hydrophobicity of sulfur atoms and benzene rings in the molecular structure.
As for chemical properties, the chemical activity of 4-chlorobenzylsulfamide is derived from the functional groups in its molecular structure. The amide group is connected to the sulfur atom, giving the molecule unique chemical activity. In the amide group, the nitrogen atom has a lone pair of electrons, making it alkaline and can react with acids to form corresponding salts. The sulfur atom also has high reactivity and is easy to participate in the redox reaction. For example, under the action of appropriate oxidants, sulfur atoms can be oxidized to higher valence states, such as sulfoxide or sulfone. In addition, chlorine atoms on the benzene ring are also reactive. In nucleophilic substitution reactions, chlorine atoms can be replaced by other nucleophilic reagents, such as hydroxyl groups, amino groups, etc. This reaction usually requires specific reaction conditions, such as appropriate catalysts and solvents, to proceed smoothly. This property makes 4-chlorobenzothiamide an important intermediate in organic synthesis. Through nucleophilic substitution reactions, more complex organic compounds can be constructed, which are widely used in the synthesis of fine chemicals such as pharmaceuticals and pesticides.
In terms of physical properties, 4-chlorobenzolamide is often in solid form. The color of this compound is usually white to off-white crystalline powder, which is fine and uniform, and has a pure appearance, which facilitates its application in many experimental and industrial processes. Its melting point is also a key physical parameter. Generally, it is in a specific temperature range, about 170-175 ° C. The melting point characteristic is of great significance in the separation, purification and identification of compounds. In addition, its solubility characteristics are also worthy of attention. In common organic solvents, such as ethanol and acetone, it exhibits a certain solubility and can be moderately dissolved to form a homogeneous solution; in water, its solubility is poor and only slightly soluble. This property is closely related to the hydrophobicity of sulfur atoms and benzene rings in the molecular structure.
As for chemical properties, the chemical activity of 4-chlorobenzylsulfamide is derived from the functional groups in its molecular structure. The amide group is connected to the sulfur atom, giving the molecule unique chemical activity. In the amide group, the nitrogen atom has a lone pair of electrons, making it alkaline and can react with acids to form corresponding salts. The sulfur atom also has high reactivity and is easy to participate in the redox reaction. For example, under the action of appropriate oxidants, sulfur atoms can be oxidized to higher valence states, such as sulfoxide or sulfone. In addition, chlorine atoms on the benzene ring are also reactive. In nucleophilic substitution reactions, chlorine atoms can be replaced by other nucleophilic reagents, such as hydroxyl groups, amino groups, etc. This reaction usually requires specific reaction conditions, such as appropriate catalysts and solvents, to proceed smoothly. This property makes 4-chlorobenzothiamide an important intermediate in organic synthesis. Through nucleophilic substitution reactions, more complex organic compounds can be constructed, which are widely used in the synthesis of fine chemicals such as pharmaceuticals and pesticides.
What is 4-chlorobenzenecarbothioamide synthesis method?
The synthesis of 4-chlorobenzothiamide, an ancient recipe, is also used today. The method is roughly as follows:
First, 4-chlorobenzoic acid is used as the starting material, which is the basis for synthesis. First, 4-chlorobenzoic acid and thionyl chloride are co-placed in a kettle, applied to a moderate temperature, and stirred. When the two are heated, the carboxyl group of 4-chlorobenzoic acid reacts with thionyl chloride to form 4-chlorobenzoyl chloride. The key to this step is to control the temperature properly and not to be too strong to prevent side reactions from clumping.
4-chlorobenzoyl chloride is obtained, and then mixed with ammonium thiocyanate. In a suitable solvent, such as ethanol, the two interact. If necessary, continue to stir in the meantime to make it fully blend. This step aims to make the chlorine atom replaced by thiocyanate, and gradually produce 4-chlorobenzyl thiocyanate.
Then, 4-chlorobenzyl thiocyanate reacts with the ammonia source. Liquid ammonia can be used, or ammonia gas can be introduced into the reaction system. Ammonia meets 4-chlorobenzyl thiocyanate, and nucleophilic substitution occurs. The thiocyanate group is attacked by ammonia, and finally 4-chlorobenzyl thiamide is obtained. This step should pay attention to the amount of ammonia, too much or too little can cause changes in yield.
The process of synthesis requires fineness, and the temperature control, proportion of materials used, and reaction time at each step are all crucial to success or failure. Only with careful care can pure 4-chlorobenzolamide be obtained to meet all requirements.
First, 4-chlorobenzoic acid is used as the starting material, which is the basis for synthesis. First, 4-chlorobenzoic acid and thionyl chloride are co-placed in a kettle, applied to a moderate temperature, and stirred. When the two are heated, the carboxyl group of 4-chlorobenzoic acid reacts with thionyl chloride to form 4-chlorobenzoyl chloride. The key to this step is to control the temperature properly and not to be too strong to prevent side reactions from clumping.
4-chlorobenzoyl chloride is obtained, and then mixed with ammonium thiocyanate. In a suitable solvent, such as ethanol, the two interact. If necessary, continue to stir in the meantime to make it fully blend. This step aims to make the chlorine atom replaced by thiocyanate, and gradually produce 4-chlorobenzyl thiocyanate.
Then, 4-chlorobenzyl thiocyanate reacts with the ammonia source. Liquid ammonia can be used, or ammonia gas can be introduced into the reaction system. Ammonia meets 4-chlorobenzyl thiocyanate, and nucleophilic substitution occurs. The thiocyanate group is attacked by ammonia, and finally 4-chlorobenzyl thiamide is obtained. This step should pay attention to the amount of ammonia, too much or too little can cause changes in yield.
The process of synthesis requires fineness, and the temperature control, proportion of materials used, and reaction time at each step are all crucial to success or failure. Only with careful care can pure 4-chlorobenzolamide be obtained to meet all requirements.
4-chlorobenzenecarbothioamide what are the precautions during use
4-Chlorobenzolamide is a special chemical substance, and many points need to be paid attention to during use.
First of all, it is about safety protection. Because of its chemical activity, do not be careless when coming into contact with it. Be sure to wear appropriate protective equipment, such as gloves, goggles and protective clothing. This is to prevent the substance from coming into direct contact with the skin and eyes, so as not to cause irritation or even more serious injury. If you contact it inadvertently, you should immediately rinse it with plenty of water and seek medical attention quickly according to the specific situation.
Second, storage should not be ignored. Store it in a dry, cool and well-ventilated place, away from fire and heat sources. Due to its flammability or easily decomposed by heat, improper storage is prone to danger. At the same time, it should be stored separately from oxidants, acids and other substances to prevent chemical reactions and accidents.
Furthermore, the operating specifications during use are extremely critical. It is necessary to strictly follow the established operating procedures to precisely control the usage and reaction conditions. Whether it is used for experimental research or industrial production, a slight deviation may cause the reaction to go out of control, affect the quality of the product, and even endanger the safety of personnel and the environment. The operation site should be equipped with perfect ventilation equipment to discharge harmful gases that may be generated in a timely manner.
In addition, the waste of this substance must not be discarded at will. Relevant environmental regulations must be followed and properly disposed of. Because it may cause pollution to the environment, reasonable disposal can minimize the harm to the ecological environment. In short, when using 4-chlorobenzolamide, many aspects such as safety, storage, operation and waste disposal need to be treated with caution, and no sloppiness should be tolerated.
First of all, it is about safety protection. Because of its chemical activity, do not be careless when coming into contact with it. Be sure to wear appropriate protective equipment, such as gloves, goggles and protective clothing. This is to prevent the substance from coming into direct contact with the skin and eyes, so as not to cause irritation or even more serious injury. If you contact it inadvertently, you should immediately rinse it with plenty of water and seek medical attention quickly according to the specific situation.
Second, storage should not be ignored. Store it in a dry, cool and well-ventilated place, away from fire and heat sources. Due to its flammability or easily decomposed by heat, improper storage is prone to danger. At the same time, it should be stored separately from oxidants, acids and other substances to prevent chemical reactions and accidents.
Furthermore, the operating specifications during use are extremely critical. It is necessary to strictly follow the established operating procedures to precisely control the usage and reaction conditions. Whether it is used for experimental research or industrial production, a slight deviation may cause the reaction to go out of control, affect the quality of the product, and even endanger the safety of personnel and the environment. The operation site should be equipped with perfect ventilation equipment to discharge harmful gases that may be generated in a timely manner.
In addition, the waste of this substance must not be discarded at will. Relevant environmental regulations must be followed and properly disposed of. Because it may cause pollution to the environment, reasonable disposal can minimize the harm to the ecological environment. In short, when using 4-chlorobenzolamide, many aspects such as safety, storage, operation and waste disposal need to be treated with caution, and no sloppiness should be tolerated.
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