Linshang Chemical
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4-Chlorobenzenecarboximidamide
Linshang Chemical
|
HS Code |
953976 |
| Chemical Formula | C7H7ClN2 |
| Molecular Weight | 154.597 g/mol |
| Appearance | Solid (usually white to off - white) |
| Odor | Typical organic chemical odor |
| Melting Point | 147 - 150 °C |
| Solubility In Water | Slightly soluble |
| Solubility In Organic Solvents | Soluble in polar organic solvents like ethanol, acetone |
| Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 4-Chlorobenzenecarboximidamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4 - chlorobenzenecarboximidamide in sealed chemical - grade plastic bags. |
| Storage | 4 - chlorobenzenecarboximidamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and incompatible substances such as strong acids and bases. Store in a tightly - sealed container to prevent moisture absorption and potential degradation. Label the storage container clearly to avoid mix - ups. |
| Shipping | 4 - chlorobenzenecarboximidamide, a chemical, is shipped in accordance with strict hazardous materials regulations. It's carefully packaged in corrosion - resistant containers, labeled clearly, and transported by approved carriers to ensure safety during transit. |
Competitive 4-Chlorobenzenecarboximidamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 4-Chlorobenzenecarboximidamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 4-chlorobenzenecarboximidamide?
4-chlorobenzenecarboximidamide, one of the organic compounds. To clarify its chemical structure, it should be analyzed from its name. "4-chloro-" shows that the fourth position of the benzene ring has a chlorine atom substituted. "Benzenecarbox-" shows that this compound is related to benzoyl group, and "imidamide" refers to its imidamide-containing functional group.
Its structure is based on the benzene ring. The benzene ring is a six-membered carbon ring with a conjugated double bond system, which gives it special stability and chemical properties. At the fourth position of the benzene ring, the chlorine atom is covalently bonded to the carbon atom. One end of the benzene ring is connected to the imidamide group derived from the carboxyl group through imidization. In this iminamide group, carbon and nitrogen are connected by double bonds, and there are amino groups next to the nitrogen atoms.
Specifically, the carbon atoms of the iminamide part are bonded with the carbon of the benzene ring to build the basic structure of the molecule. Its structural characteristics determine its chemical activity. For example, due to the electronegativity of the chlorine atom, the electron cloud density distribution of the benzene ring changes, which affects the reactivity such as electrophilic substitution. The nitrogen and oxygen atoms of the iminamide functional group can participate in various reactions, such as reacting with electrophilic reagents, or participating in intermolecular interactions as hydrogen bond donors or receptors. In summary, the chemical structure of 4-chlorobenzenecarboximidamide is cleverly combined with benzene ring, chlorine atom and iminamide group, resulting in its unique chemical behavior and properties.
Its structure is based on the benzene ring. The benzene ring is a six-membered carbon ring with a conjugated double bond system, which gives it special stability and chemical properties. At the fourth position of the benzene ring, the chlorine atom is covalently bonded to the carbon atom. One end of the benzene ring is connected to the imidamide group derived from the carboxyl group through imidization. In this iminamide group, carbon and nitrogen are connected by double bonds, and there are amino groups next to the nitrogen atoms.
Specifically, the carbon atoms of the iminamide part are bonded with the carbon of the benzene ring to build the basic structure of the molecule. Its structural characteristics determine its chemical activity. For example, due to the electronegativity of the chlorine atom, the electron cloud density distribution of the benzene ring changes, which affects the reactivity such as electrophilic substitution. The nitrogen and oxygen atoms of the iminamide functional group can participate in various reactions, such as reacting with electrophilic reagents, or participating in intermolecular interactions as hydrogen bond donors or receptors. In summary, the chemical structure of 4-chlorobenzenecarboximidamide is cleverly combined with benzene ring, chlorine atom and iminamide group, resulting in its unique chemical behavior and properties.
What are the main uses of 4-chlorobenzenecarboximidamide?
4-Chlorobenzamidine has a wide range of main uses. In the field of organic synthesis, it can be called a key intermediate. With its unique chemical structure, it can participate in many chemical reactions to build various complex organic compounds. For example, when synthesizing specific drug molecules, it can be used as an important starting material to build a molecular framework with specific pharmacological activities through ingenious reaction steps.
In the pharmaceutical industry, 4-chlorobenzamidine also plays an important role. It can also be used as a key component in the synthesis of some antibacterial and anti-inflammatory drugs. With its chemical properties, it works synergistically with other compounds to give drugs unique therapeutic effects and contribute to human health.
In the field of agriculture, it also has a place. Or it can be used as an important raw material for synthetic pesticides. The synthesized pesticides have control effects on specific pests, which helps to ensure the robust growth of crops, increase food production, and safeguard the stability of agricultural production.
Furthermore, in the field of materials science, 4-chlorobenzamidine also shows potential uses. Or it can participate in the preparation of some functional materials, giving materials special properties, such as improving the stability and conductivity of materials, so as to expand the application range of materials and promote the progress of materials science.
In short, 4-chlorobenzamidine has important uses in many fields and plays a key role in promoting the development of various fields.
In the pharmaceutical industry, 4-chlorobenzamidine also plays an important role. It can also be used as a key component in the synthesis of some antibacterial and anti-inflammatory drugs. With its chemical properties, it works synergistically with other compounds to give drugs unique therapeutic effects and contribute to human health.
In the field of agriculture, it also has a place. Or it can be used as an important raw material for synthetic pesticides. The synthesized pesticides have control effects on specific pests, which helps to ensure the robust growth of crops, increase food production, and safeguard the stability of agricultural production.
Furthermore, in the field of materials science, 4-chlorobenzamidine also shows potential uses. Or it can participate in the preparation of some functional materials, giving materials special properties, such as improving the stability and conductivity of materials, so as to expand the application range of materials and promote the progress of materials science.
In short, 4-chlorobenzamidine has important uses in many fields and plays a key role in promoting the development of various fields.
What are the physical properties of 4-chlorobenzenecarboximidamide?
4-chlorobenzenecarboximidamide, or 4-chlorobenzamidine, is a genus of organic compounds. Its physical properties are quite important, and it is related to many properties and applications of this substance.
First, the appearance is usually white to light yellow crystalline powder. This color state characterization is convenient for identification and preliminary judgment. At the time of substance identification, this is an intuitive feature.
Then again, solubility, 4-chlorobenzamidine is slightly soluble in water. This property affects its behavior in aqueous systems. In reactions or applications involving the aqueous phase, the solubility limits its dispersion and participation in the reaction. However, it is relatively more soluble in organic solvents such as ethanol and acetone. Good solubility in organic solvents facilitates its operation in organic synthesis, extraction and separation, etc., because it can be effectively separated from the mixture or promoted to participate in the organic phase reaction by virtue of suitable organic solvents.
In terms of melting point, 4-chlorobenzamidine has a specific melting point range. Accurate melting point data is of great significance for purity determination. If the purity of the material is high, the melting point should be close to the theoretical value, and the melting range should be narrow; if it contains impurities, the melting point is often reduced and the melting range is also widened. By measuring the melting point, its purity can be quickly evaluated, which is a key step in quality control.
The density of 4-chlorobenzamidine is also an important physical property. The density value reflects the quality of the substance in a unit volume. In storage, transportation and other links, the density affects its packaging, measurement and other operations, which is of great significance to industrial production and application planning.
The physical properties of 4-chlorobenzamidine, from appearance, solubility, melting point to density, are the basis for understanding and application of this substance, and have a profound impact on its properties, preparation and application in many fields such as organic synthesis, medicinal chemistry, and materials science.
First, the appearance is usually white to light yellow crystalline powder. This color state characterization is convenient for identification and preliminary judgment. At the time of substance identification, this is an intuitive feature.
Then again, solubility, 4-chlorobenzamidine is slightly soluble in water. This property affects its behavior in aqueous systems. In reactions or applications involving the aqueous phase, the solubility limits its dispersion and participation in the reaction. However, it is relatively more soluble in organic solvents such as ethanol and acetone. Good solubility in organic solvents facilitates its operation in organic synthesis, extraction and separation, etc., because it can be effectively separated from the mixture or promoted to participate in the organic phase reaction by virtue of suitable organic solvents.
In terms of melting point, 4-chlorobenzamidine has a specific melting point range. Accurate melting point data is of great significance for purity determination. If the purity of the material is high, the melting point should be close to the theoretical value, and the melting range should be narrow; if it contains impurities, the melting point is often reduced and the melting range is also widened. By measuring the melting point, its purity can be quickly evaluated, which is a key step in quality control.
The density of 4-chlorobenzamidine is also an important physical property. The density value reflects the quality of the substance in a unit volume. In storage, transportation and other links, the density affects its packaging, measurement and other operations, which is of great significance to industrial production and application planning.
The physical properties of 4-chlorobenzamidine, from appearance, solubility, melting point to density, are the basis for understanding and application of this substance, and have a profound impact on its properties, preparation and application in many fields such as organic synthesis, medicinal chemistry, and materials science.
What are the preparation methods of 4-chlorobenzenecarboximidamide?
4-chlorobenzenecarboximidamide is 4-chlorobenzamidine, and its preparation method is as follows:
First, 4-chlorobenzonitrile can be started from 4-chlorobenzonitrile. Place 4-chlorobenzonitrile in a suitable reaction vessel, add an alcohol solvent such as methanol or ethanol, and then add an appropriate amount of strong acid, such as an alcohol solution of hydrogen chloride. Under the condition of heating and reflux, the nitrile group will react with the alcohol and acid to form a salt of the imide ester first, and then after the aminolysis step, it is treated with ammonia or ammonia alcohol solution, and the salt of the imide ester is converted into 4-chlorobenzamidine. In this process, heat reflux promotes the reaction, and strict control of the reaction temperature and time is critical. If the temperature is too high or the time is too long, it is easy to cause side reactions and affect the purity and yield of the product.
Second, 4-chlorobenzoic acid is used as the starting material. 4-chlorobenzoic acid is first reacted with dichlorosulfoxide, and the carboxyl group is converted into an acyl chloride, that is, 4-chlorobenzoyl chloride. The reaction needs to be in an anhydrous environment, and an appropriate amount of catalysts such as N, N-dimethylformamide can be added to the reaction system to accelerate the reaction. The resulting 4-chlorobenzoyl chloride is reacted with cyanamide under alkaline conditions. Common bases such as sodium carbonate or potassium carbonate need to control the pH during the reaction process, and 4-chlorobenzamidine is finally obtained through a series of reactions. This route involves two steps of acylation and subsequent cyanamide reaction, and the precise regulation of the reaction conditions in each step is essential for product acquisition.
Third, start with 4-chlorobromobenzene. 4-chlorobromobenzene reacts with magnesium chips in anhydrous ethyl ether to form a Grignard reagent, that is, 4-chlorobenzamidine bromide. The Grignard reagent reacts with cyanonitrile and then hydrolyzes to obtain 4-chlorobenzamidine. When preparing Grignard reagent, the reaction system must be anhydrous and oxygen-free, otherwise Grignard reagent is easy to decompose. Subsequent hydrolysis steps also need to control conditions to obtain the target product.
First, 4-chlorobenzonitrile can be started from 4-chlorobenzonitrile. Place 4-chlorobenzonitrile in a suitable reaction vessel, add an alcohol solvent such as methanol or ethanol, and then add an appropriate amount of strong acid, such as an alcohol solution of hydrogen chloride. Under the condition of heating and reflux, the nitrile group will react with the alcohol and acid to form a salt of the imide ester first, and then after the aminolysis step, it is treated with ammonia or ammonia alcohol solution, and the salt of the imide ester is converted into 4-chlorobenzamidine. In this process, heat reflux promotes the reaction, and strict control of the reaction temperature and time is critical. If the temperature is too high or the time is too long, it is easy to cause side reactions and affect the purity and yield of the product.
Second, 4-chlorobenzoic acid is used as the starting material. 4-chlorobenzoic acid is first reacted with dichlorosulfoxide, and the carboxyl group is converted into an acyl chloride, that is, 4-chlorobenzoyl chloride. The reaction needs to be in an anhydrous environment, and an appropriate amount of catalysts such as N, N-dimethylformamide can be added to the reaction system to accelerate the reaction. The resulting 4-chlorobenzoyl chloride is reacted with cyanamide under alkaline conditions. Common bases such as sodium carbonate or potassium carbonate need to control the pH during the reaction process, and 4-chlorobenzamidine is finally obtained through a series of reactions. This route involves two steps of acylation and subsequent cyanamide reaction, and the precise regulation of the reaction conditions in each step is essential for product acquisition.
Third, start with 4-chlorobromobenzene. 4-chlorobromobenzene reacts with magnesium chips in anhydrous ethyl ether to form a Grignard reagent, that is, 4-chlorobenzamidine bromide. The Grignard reagent reacts with cyanonitrile and then hydrolyzes to obtain 4-chlorobenzamidine. When preparing Grignard reagent, the reaction system must be anhydrous and oxygen-free, otherwise Grignard reagent is easy to decompose. Subsequent hydrolysis steps also need to control conditions to obtain the target product.
4-chlorobenzenecarboximidamide what are the precautions during use
4-Chlorobenzamidine, this is an organic compound. During use, pay attention to the following things:
First, safety protection is essential. This compound may be toxic and irritating to a certain extent. When exposed, be sure to wear appropriate protective equipment. Wear protective gloves to prevent it from contacting the skin, causing skin allergies or damage; wear protective glasses to avoid it accidentally entering the eyes and causing damage to the eyes; wear gas masks to prevent inhalation of its dust or volatile gases, which can damage the respiratory tract.
Second, storage conditions should be treated with caution. Store in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its chemical properties or environmental factors, improper storage or deterioration may even cause danger. Avoid mixing with oxidants, acids and other co-storage to prevent violent chemical reactions, such as combustion, explosion, etc.
Third, the operation process must be strictly standardized. When taking it, precisely control the dosage, and measure it with appropriate instruments according to experimental or production needs to avoid waste and excessive use of pollution and danger. Use suitable solvents to dissolve or react, and fully understand the compatibility of the selected solvent with 4-chlorobenzamidine to prevent adverse reactions. The operation should be carried out in a fume hood, and volatile gases should be discharged in time to reduce the concentration of harmful substances in the air.
Fourth, waste disposal should not be sloppy. After use, do not discard residual substances and waste at will. Follow relevant environmental protection regulations and collect them separately. According to its chemical characteristics, it should be treated by appropriate methods, such as by a professional recycling agency or degraded according to a specific chemical treatment process, to ensure that its environmental hazards are minimized.
First, safety protection is essential. This compound may be toxic and irritating to a certain extent. When exposed, be sure to wear appropriate protective equipment. Wear protective gloves to prevent it from contacting the skin, causing skin allergies or damage; wear protective glasses to avoid it accidentally entering the eyes and causing damage to the eyes; wear gas masks to prevent inhalation of its dust or volatile gases, which can damage the respiratory tract.
Second, storage conditions should be treated with caution. Store in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its chemical properties or environmental factors, improper storage or deterioration may even cause danger. Avoid mixing with oxidants, acids and other co-storage to prevent violent chemical reactions, such as combustion, explosion, etc.
Third, the operation process must be strictly standardized. When taking it, precisely control the dosage, and measure it with appropriate instruments according to experimental or production needs to avoid waste and excessive use of pollution and danger. Use suitable solvents to dissolve or react, and fully understand the compatibility of the selected solvent with 4-chlorobenzamidine to prevent adverse reactions. The operation should be carried out in a fume hood, and volatile gases should be discharged in time to reduce the concentration of harmful substances in the air.
Fourth, waste disposal should not be sloppy. After use, do not discard residual substances and waste at will. Follow relevant environmental protection regulations and collect them separately. According to its chemical characteristics, it should be treated by appropriate methods, such as by a professional recycling agency or degraded according to a specific chemical treatment process, to ensure that its environmental hazards are minimized.
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