4-Chlorobenzenesulphonamide

Linshang Chemical

Specifications

HS Code

225564

Chemical Formula C6H6ClNO2S
Molar Mass 191.63 g/mol
Appearance White to off - white crystalline powder
Odor Odorless
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in ethanol, acetone
Melting Point 149 - 151 °C
Density 1.49 g/cm³
Ph Neutral in aqueous solution
Stability Stable under normal conditions

As an accredited 4-Chlorobenzenesulphonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1 kg of 4 - chlorobenzenesulphonamide packaged in a sealed plastic - lined bag.
Storage 4 - chlorobenzenesulphonamide should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly closed container to prevent moisture absorption and contact with air. Store separately from oxidizing agents, acids, and bases to avoid potential chemical reactions. Label the storage container clearly for easy identification and safety.
Shipping 4 - Chlorobenzenesulphonamide is shipped in sealed, corrosion - resistant containers. It must comply with chemical transportation regulations, ensuring proper labeling, secure packaging to prevent leakage during transit.
Free Quote

Competitive 4-Chlorobenzenesulphonamide prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365006308

Email: info@alchemist-chem.com

4-Chlorobenzenesulphonamide 4-Chlorobenzenesulphonamide
General Information
Where to Buy 4-Chlorobenzenesulphonamide in China?
As a trusted 4-Chlorobenzenesulphonamide manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Chlorobenzenesulphonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of 4-chlorobenzenesulphonamide?
4-Chlorobenzenesulfonamide has a unique chemical structure. Looking at it, it is based on a benzene ring, which is a common aromatic ring structure in organic chemistry. Above the benzene ring, a chlorine atom (Cl) occupies one place, and the chlorine atom has a certain electronegativity, which can affect the electron cloud distribution and reactivity of the molecule.
There is also a sulfonamide group (-SO _ NH _ 2) connected to the benzene ring. In the sulfonamide group, the sulfur atom (S) forms a double bond with two oxygen atoms (O), and the electron cloud of the sulfur atom is offset due to the strong electronegativity of oxygen, so that the sulfonyl group has a certain And the nitrogen atom in the -NH2O group has a lone pair of electrons, which can participate in the formation of hydrogen bonds, which has a great impact on the physical and chemical properties of the molecule.
From the overall structure, the benzene ring of 4-chlorobenzenesulfonamide gives it certain stability and hydrophobicity, and the presence of chlorine atoms and sulfonamide groups adds its reaction characteristics and polarity. This structural characteristic makes it unique in the fields of pharmaceutical chemistry and organic synthesis. It can participate in various chemical reactions with its structural characteristics according to different needs, and derive various compounds with specific functions.
What are the main uses of 4-chlorobenzenesulphonamide?
4-Chlorobenzenesulfonamide is one of the organic compounds. It has a wide range of uses and is important in many fields.
In the field of medicine, 4-chlorobenzenesulfonamide is often the key raw material for the synthesis of drugs. For example, the preparation of some antibacterial drugs relies on its participation in the reaction to form a molecular structure with antibacterial activity, which helps the drug to resist bacteria and heal diseases.
In the field of pesticides, this compound also has an important position. It can be used as an intermediate for synthetic pesticides. It can be converted into pesticide products with insecticidal, bactericidal or weeding effects through a series of chemical reactions, protecting crops from pests and diseases, ensuring their thriving growth, and increasing agricultural yield and quality.
In the field of materials science, 4-chlorobenzenesulfonamide can be used to prepare materials with special properties. Its structural properties can endow materials with specific physical or chemical properties, such as improving the stability and solubility of materials, to meet the diverse needs of material properties in different application scenarios.
In addition, in scientific research, 4-chlorobenzenesulfonamide is an important chemical reagent for researchers to explore new chemical reactions, synthesize new compounds, and promote the development of organic chemistry, medicinal chemistry and other disciplines. Due to the unique chemical activity of chlorine atoms and sulfonamide groups in its structure, it can trigger various specific reactions, providing rich research materials and possibilities for scientific research.
What are the physical properties of 4-chlorobenzenesulphonamide?
4-Chlorobenzenesulfonamide is an organic compound. It has specific physical properties, which are described below.
Looking at its properties, under room temperature and pressure, 4-chlorobenzenesulfonamide is mostly in the state of white crystalline powder. This shape is easy to observe and process, and the white powder shape suggests that it is relatively pure and has high particle uniformity.
When it comes to the melting point, it is about 146-148 ° C. The melting point is an important physical characteristic of the substance. At this temperature, 4-chlorobenzenesulfonamide gradually melts from a solid state to a liquid state. This melting point range is relatively clear and stable, which can be used as an important basis for identifying the substance. It is of great significance in experimental operations such as material purification and identification.
In terms of solubility, 4-chlorobenzenesulfonamide has limited solubility in water. Water is a common solvent, and its dissolution in water is poor, indicating that the interaction between the substance and water molecules is weak, and the molecular polarity is quite different from that of water molecules. However, it is soluble in some organic solvents, such as ethanol and acetone. The molecular structure and polarity of organic solvents such as ethanol and acetone are more suitable for 4-chlorobenzenesulfonamide, and can form a good interaction with it to achieve dissolution. This solubility characteristic plays a key guiding role in the selection of suitable solvents to achieve specific reaction or separation purposes in chemical operations such as organic synthesis, separation and purification.
In addition, the density of 4-chlorobenzenesulfonamide is also an important physical property. Although the specific value varies slightly depending on the precise measurement conditions, its density makes the substance occupy a specific space and position in the system when participating in various reactions or mixed systems, which affects the contact and reaction process between substances.
In summary, the physical properties of 4-chlorobenzenesulfonamide, such as its white crystalline powder properties, specific melting point, unique solubility and density, are interrelated and affect each other, jointly determining its many applications and reaction characteristics in the chemical field, providing an important reference for chemical research and industrial production.
What is the preparation method of 4-chlorobenzenesulphonamide?
The preparation method of 4-chlorobenzenesulfonamide has its own unique process. First, 4-chlorobenzenesulfonic acid is used as the starting material, which is the key starting material. In a suitable reaction vessel, 4-chlorobenzenesulfonic acid is mixed with an appropriate amount of ammonia or ammonia compounds. This mixing step must be done carefully to ensure uniform contact with the material.
During the reaction, the reaction conditions need to be precisely regulated. The control of temperature is very important. Generally, it is maintained at a specific temperature range. If it is too low, the reaction will be slow, and if it is too high, it will cause side reactions to breed. Usually under mild heating, the reaction is promoted gradually. During the reaction process, closely observe the reaction phenomena, such as the color change of the system, whether there is gas escape, etc.
After the reaction is completed, the product is still mixed with impurities, and needs to be separated and purified. Commonly used methods, such as recrystallization. Select a suitable solvent, which needs to have good solubility to the product, and the solubility varies significantly when the temperature changes. The reaction product is dissolved in a hot solvent, and after cooling, 4-chlorobenzenesulfonamide is precipitated in a crystalline state. After filtration, washing, drying, etc., pure 4-chlorobenzenesulfonamide can be obtained.
Or those prepared by other paths, such as using benzene as the starting material, chlorination reaction, first to obtain chlorobenzene, then sulfonation reaction, and then ammonolysis, can also obtain the target product. However, there are many steps in this path, and the reaction of each step needs to be carefully controlled to ensure the yield and purity of each step, so that 4-chlorobenzenesulfonamide can be successfully prepared. The preparation process requires strict adherence to the operating procedures and attention to details to obtain high-quality products.
4-chlorobenzenesulphonamide safety precautions
4-Chlorobenzenesulfonamide is an organic compound, and its safety precautions are described as follows:
** First, toxicity prevention **: 4-Chlorobenzenesulfonamide is toxic and can be harmful through mouth, inhalation or skin contact. When handling this substance, be sure to wear appropriate protective equipment, such as gas masks, protective gloves and protective clothing, to avoid contact and inhalation. If you come into contact inadvertently, rinse with plenty of water immediately. If you feel unwell, seek medical attention immediately.
** Second, fire hazard **: Although it is not flammable in itself, it can decompose and produce toxic gases in case of hot topics or open flames. Therefore, it needs to be stored away from fire and heat sources, and the workplace should be equipped with suitable fire extinguishing equipment, just in case.
** Third, storage requirements **: It should be stored in a cool and well-ventilated warehouse, away from fire and heat sources. It needs to be stored separately from oxidants, acids, alkalis, etc., and should not be mixed. The storage area should be equipped with suitable materials to contain leaks to prevent environmental pollution and safety accidents caused by leaks.
** Fourth, operating specifications **: The operation process needs to be carried out in a fume hood to ensure air circulation and reduce the concentration of harmful gases. Care should be taken during operation to avoid leakage. In the event of a leak, personnel from the contaminated area of the leak should be quickly evacuated to a safe area and quarantined to strictly limit access. Emergency responders need to wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Do not let leaks come into contact with flammable substances, cut off the source of leaks as much as possible, and prevent entry into restricted spaces such as sewers and drainage ditches. In the event of a small leak, a clean shovel can be collected in a dry, clean, covered container; in the event of a large leak, build a dike or dig a pit for containment, cover it with foam to reduce steam disasters, and then transfer it to a tanker or a special collector for recycling or transportation to a waste treatment site for disposal.
** Fifth, environmental considerations **: If 4-chlorobenzenesulfonamide flows into the environment, or causes pollution to water bodies, soil, etc. It is necessary to pay attention to prevent leakage during operation and storage. If there is leakage, effective measures should be taken in time to avoid adverse effects on the surrounding environment. Waste 4-chlorobenzenesulfonamide should not be discarded at will, and should be disposed of in accordance with relevant regulations to ensure environmental safety.