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(4-Chlorobenzenesulphonyl)Acetonitrile
Linshang Chemical
|
HS Code |
320205 |
| Chemical Formula | C8H6ClNO2S |
| Molecular Weight | 215.66 |
| Appearance | Solid (usually white to off - white) |
| Melting Point | Data may vary, typically in a certain range |
| Solubility In Water | Low solubility |
| Solubility In Organic Solvents | Soluble in some organic solvents like dichloromethane, ethyl acetate |
| Purity | Can be available in different purity levels (e.g., 95%, 98% etc.) |
| Density | Data may vary based on conditions |
| Stability | Should be stored under proper conditions to maintain stability |
As an accredited (4-Chlorobenzenesulphonyl)Acetonitrile factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of (4 - chlorobenzenesulphonyl)acetonitrile packaged in a sealed plastic bag. |
| Storage | (4 - chlorobenzenesulphonyl)acetonitrile should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture absorption and vapor leakage. Label the storage container clearly to avoid misidentification and ensure proper handling. |
| Shipping | (4 - chlorobenzenesulphonyl)acetonitrile should be shipped in tightly - sealed, corrosion - resistant containers. It must be labeled properly as a chemical, following all hazardous material shipping regulations to ensure safe transportation. |
Competitive (4-Chlorobenzenesulphonyl)Acetonitrile prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading (4-Chlorobenzenesulphonyl)Acetonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
(4-chlorobenzenesulphonyl) What are the main uses of acetonitrile?
(4-Chlorobenzenesulfonyl) acetonitrile is also an organic compound. Its main uses are quite extensive, and it is often used as a key intermediate in the field of organic synthesis.
Gein (4-chlorobenzenesulfonyl) acetonitrile has a special chemical structure, and the combination of chlorine atoms, sulfonyl groups and acetonitrile groups on its benzene ring endows it with unique reactivity. In the field of medicinal chemistry, it is often used to construct compound structures with specific biological activities. Chemists can take advantage of the activity check point of this compound according to specific drug design needs, and introduce different functional groups through various chemical reactions, such as nucleophilic substitution, electrophilic addition, etc., to create new drug molecules.
In the field of materials science, it also plays an important role. It can be used as a raw material to participate in the synthesis of polymers. By chemically modifying it, the physical and chemical properties of polymers, such as solubility, thermal stability, mechanical properties, etc., can be changed to meet the needs of different material application scenarios.
In addition, in the preparation of fine chemical products, (4-chlorobenzenesulfonyl) acetonitrile is also a commonly used starting material. After multi-step reaction, it can be converted into various high-value-added fine chemicals, such as special dyes, fragrances and surfactants.
In conclusion, (4-chlorobenzenesulfonyl) acetonitrile, with its unique structure and reactivity, plays an indispensable role in many fields such as organic synthesis, medicinal chemistry, materials science, and fine chemistry, providing an important material basis and chemical tools for the development of related fields.
Gein (4-chlorobenzenesulfonyl) acetonitrile has a special chemical structure, and the combination of chlorine atoms, sulfonyl groups and acetonitrile groups on its benzene ring endows it with unique reactivity. In the field of medicinal chemistry, it is often used to construct compound structures with specific biological activities. Chemists can take advantage of the activity check point of this compound according to specific drug design needs, and introduce different functional groups through various chemical reactions, such as nucleophilic substitution, electrophilic addition, etc., to create new drug molecules.
In the field of materials science, it also plays an important role. It can be used as a raw material to participate in the synthesis of polymers. By chemically modifying it, the physical and chemical properties of polymers, such as solubility, thermal stability, mechanical properties, etc., can be changed to meet the needs of different material application scenarios.
In addition, in the preparation of fine chemical products, (4-chlorobenzenesulfonyl) acetonitrile is also a commonly used starting material. After multi-step reaction, it can be converted into various high-value-added fine chemicals, such as special dyes, fragrances and surfactants.
In conclusion, (4-chlorobenzenesulfonyl) acetonitrile, with its unique structure and reactivity, plays an indispensable role in many fields such as organic synthesis, medicinal chemistry, materials science, and fine chemistry, providing an important material basis and chemical tools for the development of related fields.
(4-chlorobenzenesulphonyl) What are the physical properties of acetonitrile
(4-Chlorobenzenesulfonyl) acetonitrile, also an organic compound. Its physical properties have several ends, which are described in detail by you today.
Under normal temperature, it is mostly white to white crystalline powder, like fine snow, with uniform and delicate texture. This form is easy to use and weigh, and it is very convenient to operate in many chemical experiments and industrial processes.
When it comes to melting point, it is about a specific temperature range. This temperature is the critical value for a substance to change from a solid state to a liquid state, which has a great impact on its purification, identification and application. Accurately knowing the melting point can help to distinguish the purity of this compound. If the purity is high, the melting point range is narrow and close to the theoretical value; if it contains impurities, the melting point is reduced and the range is wider.
Solubility is also an important physical property. In common organic solvents, such as ethanol and acetone, (4-chlorobenzenesulfonyl) acetonitrile has a certain solubility. Ethanol is a commonly used organic solvent with good mutual solubility. With this solubility, it can be dissolved into a solution for chemical reactions, so that the reaction molecules are uniformly dispersed, improving the reaction efficiency and controllability. In water, its solubility is relatively low. This characteristic can be used in the process of separation and purification. The purpose of separation is achieved by means of extraction and other means by means of insolubility between water and organic solvents.
Furthermore, its density is also one of its characteristics. Density reflects the mass per unit volume of a substance and needs to be considered in storage and transportation planning. Understanding density can help to choose appropriate storage containers and transportation methods to ensure its safety and stability.
In addition, its smell is weak, although it is not pungent and unpleasant, it is still necessary to pay attention to ventilation during operation to prevent potential harm to the human body caused by long-term inhalation.
In summary, the physical properties of (4-chlorobenzenesulfonyl) acetonitrile, such as morphology, melting point, solubility, density and odor, are of great significance in chemical research, industrial production and related applications, providing a basis for its rational use and disposal.
Under normal temperature, it is mostly white to white crystalline powder, like fine snow, with uniform and delicate texture. This form is easy to use and weigh, and it is very convenient to operate in many chemical experiments and industrial processes.
When it comes to melting point, it is about a specific temperature range. This temperature is the critical value for a substance to change from a solid state to a liquid state, which has a great impact on its purification, identification and application. Accurately knowing the melting point can help to distinguish the purity of this compound. If the purity is high, the melting point range is narrow and close to the theoretical value; if it contains impurities, the melting point is reduced and the range is wider.
Solubility is also an important physical property. In common organic solvents, such as ethanol and acetone, (4-chlorobenzenesulfonyl) acetonitrile has a certain solubility. Ethanol is a commonly used organic solvent with good mutual solubility. With this solubility, it can be dissolved into a solution for chemical reactions, so that the reaction molecules are uniformly dispersed, improving the reaction efficiency and controllability. In water, its solubility is relatively low. This characteristic can be used in the process of separation and purification. The purpose of separation is achieved by means of extraction and other means by means of insolubility between water and organic solvents.
Furthermore, its density is also one of its characteristics. Density reflects the mass per unit volume of a substance and needs to be considered in storage and transportation planning. Understanding density can help to choose appropriate storage containers and transportation methods to ensure its safety and stability.
In addition, its smell is weak, although it is not pungent and unpleasant, it is still necessary to pay attention to ventilation during operation to prevent potential harm to the human body caused by long-term inhalation.
In summary, the physical properties of (4-chlorobenzenesulfonyl) acetonitrile, such as morphology, melting point, solubility, density and odor, are of great significance in chemical research, industrial production and related applications, providing a basis for its rational use and disposal.
(4-chlorobenzenesulphonyl) What are the chemical properties of acetonitrile
(4-Chlorobenzenesulfonyl) acetonitrile, an organic compound with unique chemical properties. Its appearance is often white to light yellow crystalline powder, which is widely used in specific fields.
In terms of chemical activity, due to the presence of nitrile groups and benzenesulfonyl groups, these two give it active chemical properties. Nitrile groups are functional groups with high reactivity and can participate in a variety of reactions. For example, under hydrolysis conditions, nitrile groups can be converted into carboxyl groups, or converted into amine groups through reduction reactions, resulting in a series of useful compounds. The benzenesulfonyl group also has special reactivity, which can undergo nucleophilic substitution reaction. The chlorine atom on the aromatic ring is affected by the benzenesulfonyl group, which makes the position of the chlorine atom more easily attacked by the nucleophilic reagent, and then introduces different substituents to expand the structural diversity of the compound.
From the perspective of physical properties, the substance has a certain melting point and boiling point, and its melting point and boiling point are restricted by the intermolecular force. The intermolecular force is closely related to the molecular structure. For example, the presence of the benzene ring increases the rigidity of the molecule, resulting in enhanced intermolecular interaction, which affects the melting point and boiling point. In terms of solubility, (4-chlorobenzenesulfonyl) acetonitrile has a certain solubility in common organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc., but it is difficult to dissolve in water. This difference in solubility is due to the fact that its molecular structure contains hydrophobic benzene ring and polar nitrile group and sulfonyl group. As a whole, hydrophobic effect is dominant, so the solubility in water is low.
In terms of stability, (4-chlorobenzenesulfonyl) acetonitrile is relatively stable under conventional conditions, but it may react when it encounters strong oxidants, strong acids or strong bases. In case of strong bases, nitrile groups are easy to hydrolyze; in case of strong oxidants, the oxidation state of sulfur atoms may be changed
In terms of chemical activity, due to the presence of nitrile groups and benzenesulfonyl groups, these two give it active chemical properties. Nitrile groups are functional groups with high reactivity and can participate in a variety of reactions. For example, under hydrolysis conditions, nitrile groups can be converted into carboxyl groups, or converted into amine groups through reduction reactions, resulting in a series of useful compounds. The benzenesulfonyl group also has special reactivity, which can undergo nucleophilic substitution reaction. The chlorine atom on the aromatic ring is affected by the benzenesulfonyl group, which makes the position of the chlorine atom more easily attacked by the nucleophilic reagent, and then introduces different substituents to expand the structural diversity of the compound.
From the perspective of physical properties, the substance has a certain melting point and boiling point, and its melting point and boiling point are restricted by the intermolecular force. The intermolecular force is closely related to the molecular structure. For example, the presence of the benzene ring increases the rigidity of the molecule, resulting in enhanced intermolecular interaction, which affects the melting point and boiling point. In terms of solubility, (4-chlorobenzenesulfonyl) acetonitrile has a certain solubility in common organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc., but it is difficult to dissolve in water. This difference in solubility is due to the fact that its molecular structure contains hydrophobic benzene ring and polar nitrile group and sulfonyl group. As a whole, hydrophobic effect is dominant, so the solubility in water is low.
In terms of stability, (4-chlorobenzenesulfonyl) acetonitrile is relatively stable under conventional conditions, but it may react when it encounters strong oxidants, strong acids or strong bases. In case of strong bases, nitrile groups are easy to hydrolyze; in case of strong oxidants, the oxidation state of sulfur atoms may be changed
(4-chlorobenzenesulphonyl) What are the synthesis methods of acetonitrile
There are many ways to synthesize (4-chlorobenzenesulfonyl) acetonitrile. Ancient chemists often follow the following methods to make this substance.
First, use 4-chlorobenzenesulfonyl chloride and acetonitrile as the base material. First take an appropriate amount of 4-chlorobenzenesulfonyl chloride, place it in a clean reactor, slowly drop into acetonitrile, and add an appropriate amount of acid binding agent, such as triethylamine. The reaction needs to be carried out at a low temperature and stirred, and the temperature should be controlled at 0-5 ° C. The ability of the acid binding agent is to capture the acid generated by the reaction and make the reaction go smoothly to the right. After the reaction is completed, the product can be purified by conventional separation methods, such as extraction, distillation, etc., to obtain (4-chlorobenzenesulfonyl) acetonitrile.
Second, 4-chlorothiophenol is used as the starting material. First, 4-chlorothiophenol is oxidized to 4-chlorobenzenesulfonic acid. The oxidizing agent used can be hydrogen peroxide or potassium permanganate. After obtaining 4-chlorobenzenesulfonic acid, it interacts with thionyl chloride to form 4-chlorobenzenesulfonyl chloride. The subsequent step is the same as the previous method, reacts with acetonitrile in the presence of acid binding agent, and is separated and purified to obtain the target product.
Third, 4-chloroaniline is used as the starting Sodium 4-chlorobenzenesulfonate is obtained by diazotization of 4-chloroaniline and then reacting with sodium sulfite. After acidification, 4-chlorobenzenesulfonate is obtained, and then 4-chlorobenzenesulfonyl chloride is formed according to the above, and finally reacts with acetonitrile to form (4-chlorobenzenesulfonyl) acetonitrile.
All these synthesis methods have their own advantages and disadvantages. Fang Jiadang chose carefully according to the purity of the raw materials, equipment and products.
First, use 4-chlorobenzenesulfonyl chloride and acetonitrile as the base material. First take an appropriate amount of 4-chlorobenzenesulfonyl chloride, place it in a clean reactor, slowly drop into acetonitrile, and add an appropriate amount of acid binding agent, such as triethylamine. The reaction needs to be carried out at a low temperature and stirred, and the temperature should be controlled at 0-5 ° C. The ability of the acid binding agent is to capture the acid generated by the reaction and make the reaction go smoothly to the right. After the reaction is completed, the product can be purified by conventional separation methods, such as extraction, distillation, etc., to obtain (4-chlorobenzenesulfonyl) acetonitrile.
Second, 4-chlorothiophenol is used as the starting material. First, 4-chlorothiophenol is oxidized to 4-chlorobenzenesulfonic acid. The oxidizing agent used can be hydrogen peroxide or potassium permanganate. After obtaining 4-chlorobenzenesulfonic acid, it interacts with thionyl chloride to form 4-chlorobenzenesulfonyl chloride. The subsequent step is the same as the previous method, reacts with acetonitrile in the presence of acid binding agent, and is separated and purified to obtain the target product.
Third, 4-chloroaniline is used as the starting Sodium 4-chlorobenzenesulfonate is obtained by diazotization of 4-chloroaniline and then reacting with sodium sulfite. After acidification, 4-chlorobenzenesulfonate is obtained, and then 4-chlorobenzenesulfonyl chloride is formed according to the above, and finally reacts with acetonitrile to form (4-chlorobenzenesulfonyl) acetonitrile.
All these synthesis methods have their own advantages and disadvantages. Fang Jiadang chose carefully according to the purity of the raw materials, equipment and products.
(4-chlorobenzenesulphonyl) What are the precautions for acetonitrile during use
(4-Chlorobenzenesulfonyl) acetonitrile is also commonly used in chemical drugs. When it is used, many matters cannot be ignored.
The first thing to pay attention to is that this thing is poisonous, and it is very harmful when it touches the skin and eyes. Therefore, when handling, protective gear must be used on the body. Gloves, masks, eyepieces, etc. are all indispensable to resist its poison and prevent damage to the body and skin.
Second, this thing is strong in nature, and it is very easy to respond to fire and heat, or even explode. To store and use it, keep it away from fire and heat, and keep it in a cool and ventilated place. And it should not be stored or transported with strong oxygen agents, strong acids, and strong bases to prevent their formation and transformation.
Furthermore, when using it, the exact amount should be carefully controlled. Excessive use of it may cause side effects to occur frequently and damage the efficacy. And in the process of responding, the temperature and the length of time are all important factors. When in accordance with the regulations of the party, we should carefully check and control it to promote the smooth response and obtain the best effect.
Also, after use, the residue and waste should not be discarded. When in accordance with environmental protection regulations, properly dispose of it. Or dispose of it, or collect it to prevent it from polluting the ground, dyeing water, and harming the environment.
Those who handle (4-chlorobenzenesulfonyl) acetonitrile must be cautious, observe all matters, and abide by the rules in order to keep themselves safe, smooth, and harmless to the environment.
The first thing to pay attention to is that this thing is poisonous, and it is very harmful when it touches the skin and eyes. Therefore, when handling, protective gear must be used on the body. Gloves, masks, eyepieces, etc. are all indispensable to resist its poison and prevent damage to the body and skin.
Second, this thing is strong in nature, and it is very easy to respond to fire and heat, or even explode. To store and use it, keep it away from fire and heat, and keep it in a cool and ventilated place. And it should not be stored or transported with strong oxygen agents, strong acids, and strong bases to prevent their formation and transformation.
Furthermore, when using it, the exact amount should be carefully controlled. Excessive use of it may cause side effects to occur frequently and damage the efficacy. And in the process of responding, the temperature and the length of time are all important factors. When in accordance with the regulations of the party, we should carefully check and control it to promote the smooth response and obtain the best effect.
Also, after use, the residue and waste should not be discarded. When in accordance with environmental protection regulations, properly dispose of it. Or dispose of it, or collect it to prevent it from polluting the ground, dyeing water, and harming the environment.
Those who handle (4-chlorobenzenesulfonyl) acetonitrile must be cautious, observe all matters, and abide by the rules in order to keep themselves safe, smooth, and harmless to the environment.
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