4-Chlorobenzenethiol

Linshang Chemical

Specifications

HS Code

991344

Chemical Formula C6H5ClS
Molar Mass 144.62 g/mol
Appearance Colorless to pale yellow liquid
Odor Pungent sulfur - like odor
Density 1.265 g/cm³ at 25 °C
Boiling Point 204 - 206 °C
Melting Point −15 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 87 °C
Vapor Pressure Low vapor pressure at room temperature
Acidity Weakly acidic due to the thiol group

As an accredited 4-Chlorobenzenethiol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 4 - chlorobenzenethiol packaged in a tightly - sealed, corrosion - resistant bottle.
Storage 4 - Chlorobenzenethiol should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly - sealed container to prevent vapor release. Due to its potential reactivity and toxicity, store it separately from oxidizing agents, acids, and bases. Ensure storage areas comply with safety regulations to avoid environmental and safety hazards.
Shipping 4 - Chlorobenzenethiol is shipped in sealed, corrosion - resistant containers. Special care is taken due to its chemical nature. Shipments follow strict regulations to ensure safe transport, avoiding exposure to heat, oxidants, and incompatible substances.
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4-Chlorobenzenethiol 4-Chlorobenzenethiol
General Information
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As a trusted 4-Chlorobenzenethiol manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Chlorobenzenethiol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-chlorobenzenethiol?
4-Chlorobenzenethiol (4-chlorobenzenethiol) is also an organic compound. It has a wide range of main uses and is useful in various fields.
First, it is often a key intermediate in the field of organic synthesis. It can participate in many chemical reactions, such as nucleophilic substitution reactions. With its activity of thiophenol groups, it can interact with a variety of halogenated hydrocarbons, acyl halides and other compounds to form new carbon-sulfur bonds or other functionalized structures. Through such reactions, a variety of organic compounds can be prepared, such as drugs, pesticides and fine chemicals.
Second, it also has important uses in materials science. It can be used as a modifier to regulate the surface properties of materials. For example, on the surface of some metal materials, 4-chlorothiophenol can self-assemble to form a monolayer due to the strong interaction between sulfur atoms and metals. This monolayer can improve the wettability and corrosion resistance of the material surface. In the field of nanomaterials, it can also be used to modify the surface of nanoparticles to regulate the dispersion, stability and interaction with the surrounding environment of nanoparticles.
Third, in the field of pharmaceutical research and development, compounds derived from 4-chlorothiophenol may have certain biological activities. Some compounds have been shown to have effects on specific biological targets and can be used as lead compounds for medical researchers to explore in depth to develop new drugs for the treatment of diseases.
In summary, 4-chlorothiophenol plays an important role in organic synthesis, materials science, pharmaceutical research and development, and has made significant contributions to the development of various related fields.
What are the physical properties of 4-chlorobenzenethiol?
4-Chlorothiophenol is an organic compound. It has many physical properties, which are described as follows:
Looking at its properties, under room temperature and pressure, 4-chlorothiophenol is a colorless to light yellow liquid, but it can be left for a long time or easily discolored when seen in light. This substance has a special odor, which is more pungent and uncomfortable to smell.
When it comes to the melting point, its melting point is about -15 ° C, and its boiling point is 235-237 ° C. The melting point is relatively low, so it is liquid at room temperature; the boiling point is quite high, indicating that a higher temperature is required to vaporize it.
In terms of solubility, 4-chlorothiophenol is slightly soluble in water, but soluble in organic solvents such as ethanol, ether, and benzene. This is because water is a polar solvent, while the polarity of 4-chlorothiophenol molecules is relatively weak. According to the principle of "similar miscibility", its solubility in water is poor, while it is well miscible with organic solvents with similar polarity.
In terms of density, it is about 1.32g/cm ³, which is higher than the density of water, so if mixed with water, it will sink to the bottom of the water.
In addition, 4-chlorothiophenol has a low vapor pressure and relatively small volatility. However, in a poorly heated or ventilated environment, a certain amount of steam will still evaporate into the air. Its steam and air can form explosive mixtures, causing combustion and explosion in case of open flames and high heat, so special attention should be paid to safety when using it.
What is the chemistry of 4-chlorobenzenethiol?
4-Chlorothiophenol is an organic compound. It is active and has unique chemical properties.
In this substance, the chlorine atom is connected to the benzene ring, giving it a specific electronic effect. The chlorine atom has electron absorption, which can affect the electron cloud density distribution of the benzene ring. On the benzene ring, the electron cloud density of the ortho and para-position is relatively reduced, resulting in a change in the electrophilic substitution reaction activity compared with benzene. When the electrophilic reagent attacks, the selectivity of the reaction check point is also affected by the positioning effect of the chlorine atom.
Furthermore, thiophenol (-SH) is another key functional group of 4-chlorothiophenol. The sulfur atom of thiophenol has a solitary pair of electrons and is alkaline to a certain extent, but its basicity is weaker than that of alcohol hydroxyl groups. At the same time, the S-H bond energy in -SH is relatively small, and the sulfur-hydrogen bond is easy to break, so that 4-chlorothiophenol exhibits a certain acidity and can react with bases to form corresponding salts.
The sulfur atom of 4-chlorothiophenol has rich valence electrons and is easily oxidized. In case of suitable oxidants, it can be oxidized to sulfoxides or sulfones. In addition, its thiophenol groups can participate in a variety of organic reactions, such as nucleophilic substitution reactions. Under appropriate conditions, thiophenol-based sulfur atoms can be used as nucleophiles to attack halogenated hydrocarbons and other electrophilic reagents, form new carbon-sulfur bonds, and construct more complex organic molecular structures.
It has a wide range of uses in the field of organic synthesis and can be used as intermediates to participate in the preparation of drugs, pesticides and functional materials. However, when using it, pay attention to its toxicity and irritation, and take protective measures.
What are the precautions 4-chlorobenzenethiol in the production process?
4-Chlorothiophenol must be kept in mind during production.
The first safety protection. This substance is toxic and irritating, and operators should strictly wear protective equipment, such as gas masks, protective gloves, protective glasses, etc., to avoid contact with the skin, eyes, and respiratory tract. It is necessary to work in a well-ventilated environment. If it is in a closed space, effective ventilation facilities must be set up to disperse harmful gases in time, reduce their concentration in the air, and reduce the risk of poisoning.
Furthermore, storage should also be cautious. It should be stored in a cool and ventilated warehouse, away from fire and heat sources. It should be stored separately from oxidants and acids, and should not be mixed. The storage area should be equipped with suitable containment materials to prevent leakage accidents.
During the production process, accurate temperature control, pressure control and reaction time are required. The reactions in which this substance participates are often harsh on conditions, deviations in conditions, or cause abnormal reactions, impure products, or even cause safety accidents. And stirring should be uniform to ensure that the reactants are fully contacted and the reaction is smooth.
And the maintenance and inspection of equipment should not be underestimated. Regularly check the sealing of equipment to prevent leakage; check pipes, valves and other components to ensure that they are not blocked, damaged, and operate normally.
Waste disposal is also key. Waste containing 4-chlorothiophenol should be properly disposed of in accordance with relevant environmental regulations and should not be discharged at will. Chemical treatment, incineration and other methods can be used to degrade its toxicity and meet environmental protection standards.
In short, the production process of 4-chlorothiophenol, safety, storage, operation, equipment and waste disposal, are all related to the smooth production, personnel safety and environmental protection.
What is the market price range for 4-chlorobenzenethiol?
4-Chlorothiophenol is one of the organic compounds and is widely used in chemical, pharmaceutical, materials and other fields. As for its market price range, it is difficult to say exactly, because it is affected by many factors.
The first to bear the brunt is the cost of raw materials. The preparation of 4-chlorothiophenol often uses chlorobenzene, sodium hydrosulfide, etc. as raw materials. If the price of these raw materials fluctuates due to changes in market supply and demand, origin, season, etc., the cost of 4-chlorothiophenol will be affected, which will cause its market price to change.
Furthermore, the difficulty of the preparation process is also the key. The process of preparing 4-chlorothiophenol is complex, requiring fine operation and professional equipment, and strict control of reaction conditions. The higher the difficulty of the process, the higher the production cost, and the higher the price.
The market supply and demand situation should not be underestimated. If the market has strong demand for 4-chlorothiophenol and limited supply, its price will rise; conversely, if the supply exceeds demand, the price will inevitably fall.
In addition, the brand, scale and sales channels of the manufacturer all affect the price. The quality of the products produced by well-known large factories may be better, and the price may be slightly higher; while the prices of small factories may be competitive.
As far as I know, the current market price of 4-chlorothiophenol ranges from a few hundred to several thousand yuan per kilogram. However, this is only a rough estimate. The actual price needs to be consulted with relevant suppliers or on the chemical product trading platform to obtain an accurate figure. After all, the price of chemical products is changeable and is often adjusted at any time according to market conditions.