Linshang Chemical
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4-Chlorobutanesulfonyl P-Benzenesulfonamide
Linshang Chemical
|
HS Code |
572415 |
| Chemical Formula | C10H14ClNO4S2 |
| Molecular Weight | 311.81 |
| Appearance | Solid (usually white or off - white) |
| Melting Point | Data may vary, typically in a specific range |
| Solubility In Water | Limited solubility |
| Solubility In Organic Solvents | Soluble in some common organic solvents |
| Purity | Varies depending on production, often high - purity grades available |
| Density | Characteristic density value |
| Odor | May have a faint, characteristic odor |
| Stability | Stable under normal storage conditions |
As an accredited 4-Chlorobutanesulfonyl P-Benzenesulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 4 - chlorobutanesulfonyl P - benzenesulfonamide in sealed plastic bags. |
| Storage | 4 - chlorobutanesulfonyl P - benzenesulfonamide should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly closed container to prevent moisture absorption and contamination. This helps maintain its chemical integrity and reduces the risk of decomposition or unwanted reactions. |
| Shipping | 4 - chlorobutanesulfonyl P - benzenesulfonamide should be shipped in well - sealed, corrosion - resistant containers. Ensure compliance with chemical shipping regulations, and handle with care to prevent leakage during transit. |
Competitive 4-Chlorobutanesulfonyl P-Benzenesulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Chlorobutanesulfonyl P-Benzenesulfonamide in China?
As a trusted 4-Chlorobutanesulfonyl P-Benzenesulfonamide manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Chlorobutanesulfonyl P-Benzenesulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 4-chlorobutanesulfonyl P-benzenesulfonamide?
The chemical structure of 4-chlorobutanesulfonyl-p-benzenesulfonamide needs to be analyzed in detail. This compound contains a sulfonamide group, that is, the sulfonyl group is connected to the amino group, and the p-benzenesulfonamide part is one of the benzene rings connected to the sulfonamide group, and there are other substitutions at the para-site. The 4-chlorobutanesulfonyl group is a chlorine atom substituted at the 4-position of the butane chain, and the sulfonyl group is attached at one end.
Looking at its overall structure, the p-benzenesulfonamide is used as the core, and one end of the sulfonyl group is connected to the sulfonyl group of the 4-chlorobutanesul The carbon chain of 4-chlorobutane may give this compound a specific spatial conformation and physicochemical properties. The presence of chlorine atoms, due to their electronegativity, or affecting molecular polarity, can lead to reactions such as nucleophilic substitution in chemical reactions, or become active check points.
The benzene ring of p-benzenesulfonamide has aromatic properties, which can participate in electron delocalization and affect molecular stability and reactivity. In the sulfonamide group, the hydrogen on the nitrogen atom may have a certain acidity, which can participate in acid-base related reactions. Overall, the chemical structure of 4-chlorobutanesulfonyl-p-benzenesulfonamide integrates the characteristics of various chemical groups, and its unique structure determines its potential use in organic synthesis, medicinal chemistry, and other fields.
Looking at its overall structure, the p-benzenesulfonamide is used as the core, and one end of the sulfonyl group is connected to the sulfonyl group of the 4-chlorobutanesul The carbon chain of 4-chlorobutane may give this compound a specific spatial conformation and physicochemical properties. The presence of chlorine atoms, due to their electronegativity, or affecting molecular polarity, can lead to reactions such as nucleophilic substitution in chemical reactions, or become active check points.
The benzene ring of p-benzenesulfonamide has aromatic properties, which can participate in electron delocalization and affect molecular stability and reactivity. In the sulfonamide group, the hydrogen on the nitrogen atom may have a certain acidity, which can participate in acid-base related reactions. Overall, the chemical structure of 4-chlorobutanesulfonyl-p-benzenesulfonamide integrates the characteristics of various chemical groups, and its unique structure determines its potential use in organic synthesis, medicinal chemistry, and other fields.
What are the main uses of 4-chlorobutanesulfonyl P-benzenesulfonamide?
4-Chlorobutanesulfonyl p-benzenesulfonamide is widely used. In the field of medicine, it is often used as a key intermediate to assist in the development and synthesis of medicine, or involved in antibacterial and anti-inflammatory drugs. With its special chemical structure, it endows drugs with specific activities and efficacy, and precisely acts with targets in the body to achieve the purpose of treating diseases.
In the field of materials science, it can participate in the preparation of special materials. For example, chemically modified, combined with polymer materials, to improve material properties, such as improving material stability, enhancing its corrosion resistance, etc., to make materials more durable and reliable in specific environments.
In the field of organic synthesis, it is an important synthetic building block, providing convenience for the construction of complex organic molecules. With unique functional groups, organic compounds with diverse structures and functions can be derived through various organic reactions and splicing with other compounds, expanding the possibility of organic synthesis and laying the foundation for the development of new organic materials and compounds. In short, 4-chlorobutanesulfonyl p-benzenesulfonamide is of great significance in many fields and plays a key role in promoting the development of various fields.
In the field of materials science, it can participate in the preparation of special materials. For example, chemically modified, combined with polymer materials, to improve material properties, such as improving material stability, enhancing its corrosion resistance, etc., to make materials more durable and reliable in specific environments.
In the field of organic synthesis, it is an important synthetic building block, providing convenience for the construction of complex organic molecules. With unique functional groups, organic compounds with diverse structures and functions can be derived through various organic reactions and splicing with other compounds, expanding the possibility of organic synthesis and laying the foundation for the development of new organic materials and compounds. In short, 4-chlorobutanesulfonyl p-benzenesulfonamide is of great significance in many fields and plays a key role in promoting the development of various fields.
What is the preparation method of 4-chlorobutanesulfonyl P-benzenesulfonamide?
The preparation of 4-chlorobutanesulfonyl p-benzenesulfonamide is an important matter for fine chemical synthesis. In this step, p-benzenesulfonamide is first taken as the starting material, which lays the foundation like a cornerstone in the reaction system.
Next, 4-chlorobutanesulfonyl is introduced. 4-chlorobutanesulfonyl chloride is often used as a reagent, because the chlorine atom is active, and it is easy to undergo nucleophilic substitution reaction with the nitrogen atom of p-benzenesulfonamide. The reaction environment is quite critical, and it is mostly selected in organic solvents, such as dichloromethane and chloroform. Such solvents can not only dissolve the reactants well, but also help the reaction to progress smoothly.
In order to make the reaction smooth, the choice of catalyst cannot be ignored. Base catalysts, such as triethylamine, pyridine, etc., can effectively promote the reaction. Its function is to capture the protons on the nitrogen atom of p-benzenesulfonamide, enhance the nucleophilicity of the nitrogen atom, and accelerate the nucleophilic substitution step.
During the reaction, temperature control is extremely important. Generally speaking, the reaction rate is slow at low temperatures, and high temperatures may cause side reactions to breed. Therefore, the temperature is usually maintained in a moderate range, about 0 ° C to room temperature, and the specific needs to be flexibly adjusted according to the reaction process and actual conditions.
After the reaction is completed, the separation and purification of the product are also key. The product can be extracted by extraction with a suitable organic solvent, and then preliminarily purified by washing, drying and other steps. Then it is further purified by column chromatography or recrystallization to obtain a pure 4-chlorobutanesulfonyl p-benzenesulfonamide product. This whole process requires fine operation, and each link is closely linked to obtain high-quality products.
Next, 4-chlorobutanesulfonyl is introduced. 4-chlorobutanesulfonyl chloride is often used as a reagent, because the chlorine atom is active, and it is easy to undergo nucleophilic substitution reaction with the nitrogen atom of p-benzenesulfonamide. The reaction environment is quite critical, and it is mostly selected in organic solvents, such as dichloromethane and chloroform. Such solvents can not only dissolve the reactants well, but also help the reaction to progress smoothly.
In order to make the reaction smooth, the choice of catalyst cannot be ignored. Base catalysts, such as triethylamine, pyridine, etc., can effectively promote the reaction. Its function is to capture the protons on the nitrogen atom of p-benzenesulfonamide, enhance the nucleophilicity of the nitrogen atom, and accelerate the nucleophilic substitution step.
During the reaction, temperature control is extremely important. Generally speaking, the reaction rate is slow at low temperatures, and high temperatures may cause side reactions to breed. Therefore, the temperature is usually maintained in a moderate range, about 0 ° C to room temperature, and the specific needs to be flexibly adjusted according to the reaction process and actual conditions.
After the reaction is completed, the separation and purification of the product are also key. The product can be extracted by extraction with a suitable organic solvent, and then preliminarily purified by washing, drying and other steps. Then it is further purified by column chromatography or recrystallization to obtain a pure 4-chlorobutanesulfonyl p-benzenesulfonamide product. This whole process requires fine operation, and each link is closely linked to obtain high-quality products.
What are the physical properties of 4-chlorobutanesulfonyl P-benzenesulfonamide?
4-Chlorobutanesulfonyl p-benzenesulfonamide, this is an organic compound. Its physical properties are crucial and related to applications in many fields.
First of all, the appearance of this compound is usually white to off-white crystalline powder, with a fine appearance and uniform texture. This appearance feature is not only easy to identify, but also in some chemical processes that require precise control, because it is easy to distinguish, it is conducive to controlling the reaction process.
Besides solubility, it shows good solubility in common organic solvents such as dichloromethane and chloroform, and can be evenly dispersed in it, just like fish swimming in water, natural fusion. However, in water, its solubility is not good, and it is difficult to blend with water affinity. This property is of great significance in the separation, purification and construction of specific reaction systems. For example, if you want to separate this substance from a mixture, you can choose a suitable solvent according to the difference in its solubility in different solvents to achieve effective separation.
Melting point is also an important physical property. It has a certain melting point range, at which temperature the solid will gradually melt into a liquid state. This melting point temperature is stable and measurable, like a specific threshold, providing a key basis for the identification of this compound. In the quality control process, the purity can be judged by measuring the melting point. If the measured melting point matches or is similar to the standard value, it indicates that the purity is high; if the deviation is large, the purity is questionable.
In addition, the density of 4-chlorobutanesulfonyl p-benzenesulfonamide is also a specific value. This density characteristic is crucial in storage and transportation. Knowing its density can reasonably plan the storage container capacity and transportation load, ensure the process is safe and efficient, and avoid conditions such as container overload or improper transportation arrangements due to insufficient density awareness.
First of all, the appearance of this compound is usually white to off-white crystalline powder, with a fine appearance and uniform texture. This appearance feature is not only easy to identify, but also in some chemical processes that require precise control, because it is easy to distinguish, it is conducive to controlling the reaction process.
Besides solubility, it shows good solubility in common organic solvents such as dichloromethane and chloroform, and can be evenly dispersed in it, just like fish swimming in water, natural fusion. However, in water, its solubility is not good, and it is difficult to blend with water affinity. This property is of great significance in the separation, purification and construction of specific reaction systems. For example, if you want to separate this substance from a mixture, you can choose a suitable solvent according to the difference in its solubility in different solvents to achieve effective separation.
Melting point is also an important physical property. It has a certain melting point range, at which temperature the solid will gradually melt into a liquid state. This melting point temperature is stable and measurable, like a specific threshold, providing a key basis for the identification of this compound. In the quality control process, the purity can be judged by measuring the melting point. If the measured melting point matches or is similar to the standard value, it indicates that the purity is high; if the deviation is large, the purity is questionable.
In addition, the density of 4-chlorobutanesulfonyl p-benzenesulfonamide is also a specific value. This density characteristic is crucial in storage and transportation. Knowing its density can reasonably plan the storage container capacity and transportation load, ensure the process is safe and efficient, and avoid conditions such as container overload or improper transportation arrangements due to insufficient density awareness.
4-chlorobutanesulfonyl P-benzenesulfonamide safety precautions
4-Chlorobutanesulfonyl-p-benzenesulfonamide is a chemical substance, and its use and operation require special attention to many safety matters to ensure the safety of personnel and the smooth progress of experiments and production.
First, it is related to toxicity and health hazards. This substance may be toxic to a certain extent, and it is necessary to wear appropriate protective equipment during operation, such as laboratory clothes, gloves, goggles, and gas masks. If it comes into contact with the skin inadvertently, or causes skin irritation, allergies and other symptoms, if it is exposed, it should be rinsed with plenty of water immediately and seek medical attention as appropriate. If it is not accidentally entered into the eyes, it is necessary to rinse the eyes with plenty of water immediately for a few minutes, and then seek medical attention as soon as possible. If inhaling its dust or volatiles, or affecting the respiratory tract, causing cough, asthma and other discomfort, the operation should be carried out in a well-ventilated environment, preferably in a fume hood.
Second, about the risk of ignition and explosion. It is necessary to clarify the explosive characteristics of this substance, keep away from fire and heat sources, and avoid the formation of explosive dust or vapor clouds. When storing, it should be placed in a cool, dry and well-ventilated place, away from flammable and combustible materials to prevent fire and explosion accidents.
Third, the operation process is also exquisite. The operation should strictly follow the standard procedures and specifications, and do not change the operating conditions at will. Weighing, transfer and other operations should be careful to prevent substances from spilling. After the experiment is completed, properly dispose of the remaining substances and waste, follow the relevant environmental protection regulations, and do not discard them at will to avoid polluting the environment.
Fourth, storage. Storage containers should be well sealed to prevent leakage. At the same time, they should be stored separately from oxidants, acids, and bases. Do not mix storage to prevent chemical reactions. Regularly check whether the storage container is damaged or leaked. If there is any abnormality, deal with it in time.
In short, the operation and use of 4-chlorobutanesulfonyl-p-benzenesulfonamide must be fully aware of its safety characteristics, strictly implement safety procedures, and must not be taken lightly to ensure the safety of personnel and the environment.
First, it is related to toxicity and health hazards. This substance may be toxic to a certain extent, and it is necessary to wear appropriate protective equipment during operation, such as laboratory clothes, gloves, goggles, and gas masks. If it comes into contact with the skin inadvertently, or causes skin irritation, allergies and other symptoms, if it is exposed, it should be rinsed with plenty of water immediately and seek medical attention as appropriate. If it is not accidentally entered into the eyes, it is necessary to rinse the eyes with plenty of water immediately for a few minutes, and then seek medical attention as soon as possible. If inhaling its dust or volatiles, or affecting the respiratory tract, causing cough, asthma and other discomfort, the operation should be carried out in a well-ventilated environment, preferably in a fume hood.
Second, about the risk of ignition and explosion. It is necessary to clarify the explosive characteristics of this substance, keep away from fire and heat sources, and avoid the formation of explosive dust or vapor clouds. When storing, it should be placed in a cool, dry and well-ventilated place, away from flammable and combustible materials to prevent fire and explosion accidents.
Third, the operation process is also exquisite. The operation should strictly follow the standard procedures and specifications, and do not change the operating conditions at will. Weighing, transfer and other operations should be careful to prevent substances from spilling. After the experiment is completed, properly dispose of the remaining substances and waste, follow the relevant environmental protection regulations, and do not discard them at will to avoid polluting the environment.
Fourth, storage. Storage containers should be well sealed to prevent leakage. At the same time, they should be stored separately from oxidants, acids, and bases. Do not mix storage to prevent chemical reactions. Regularly check whether the storage container is damaged or leaked. If there is any abnormality, deal with it in time.
In short, the operation and use of 4-chlorobutanesulfonyl-p-benzenesulfonamide must be fully aware of its safety characteristics, strictly implement safety procedures, and must not be taken lightly to ensure the safety of personnel and the environment.
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