4-(Chlorodifluoromethoxy)Nitrobenzene

Linshang Chemical

Specifications

HS Code

306994

Chemical Formula C7H3ClF2NO3
Molar Mass 223.55 g/mol

As an accredited 4-(Chlorodifluoromethoxy)Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500 - gram bottles of 4-(chlorodifluoromethoxy)nitrobenzene, well - sealed.
Storage 4-(Chlorodifluoromethoxy)nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames to prevent potential thermal decomposition or ignition. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials, to avoid leakage and contact with air or moisture, which could cause chemical reactions. Store separately from incompatible substances like oxidizers and reducing agents.
Shipping 4-(Chlorodifluoromethoxy)nitrobenzene is shipped in sealed, corrosion - resistant containers. Special care is taken to ensure compliance with hazardous chemical shipping regulations due to its potentially harmful nature.
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4-(Chlorodifluoromethoxy)Nitrobenzene 4-(Chlorodifluoromethoxy)Nitrobenzene
General Information
Where to Buy 4-(Chlorodifluoromethoxy)Nitrobenzene in China?
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Frequently Asked Questions

As a leading 4-(Chlorodifluoromethoxy)Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4- (chlorodifluoromethoxy) nitrobenzene?
(Hydrodioxyacetoxy) benzylnitrile, a crucial chemical substance in the field of organic synthesis, is widely used in many fields.
In the field of pharmaceutical synthesis, it can be used as a key intermediate. Due to the special chemical structure of this compound, it can be skillfully converted into various biologically active drug molecules through specific chemical reactions. For example, some drugs used to treat cardiovascular diseases play an indispensable role in the synthesis of (hydrodioxyacetoxy) benzylnitrile. With exquisite organic reaction design, its structure can be gradually derived, and finally complex drug molecules that meet pharmacological needs can be constructed, so as to achieve effective treatment of diseases.
In the field of materials science, it also shows unique value. It can be used as a starting material for the synthesis of special properties polymer materials. By polymerizing with other monomers, the resulting polymer material can be endowed with specific physical and chemical properties. For example, polymers with good solubility and thermal stability can be prepared. Such polymers are very useful in coatings, adhesives and other fields, providing novel options and directions for the development of materials science.
In the fine chemical industry, (hydrodioxyacetoxy) benzylnitrile is often used in the synthesis of high-end fine chemicals. Due to its unique structure, it can synthesize fine chemicals with special functions, such as special fragrances, cosmetic additives, etc. These fine chemicals have achieved remarkable results in improving product quality and performance, injecting vitality into the product diversification and high-end development of the fine chemical industry.
Overall, (hydrodioxyacetoxy) benzylnitrile, with its unique chemical structure, plays a key role in the fields of medicine, materials, and fine chemicals, and is of great significance in promoting technological progress and product innovation in various fields.
What are the physical properties of 4- (chlorodifluoromethoxy) nitrobenzene?
The physical properties of (cyanodiethyl ester oxy) carbonyl benzyl are as follows:
Its properties are often white to off-white crystalline powder, which is easy to observe and treat. In many chemical operations and industrial processes, this form is conducive to accurate weighing, mixing and other steps.
The melting point is in a specific range, about [X] ° C. The melting point is an important physical property of the substance, and its phase change under different temperature conditions is defined. Knowing the melting point, in the synthesis, purification and other processes, the separation of the substance from other impurities can be achieved through temperature regulation.
has a certain solubility. It exhibits good solubility in organic solvents such as ethanol and acetone. This property makes it easy to be uniformly dispersed in the reaction system as a reactant in the organic synthesis reaction, which is conducive to the full and efficient reaction. Poor solubility in water, this characteristic can be distinguished from water-soluble impurities by the aqueous phase in post-treatment processes such as separation and washing.
The density is [X] g/cm ³. The density data is related to the mass of the substance in a specific volume. In practical application scenarios such as storage and transportation, it provides a key basis for container selection and loading capacity planning.
In terms of stability, the chemical properties of the substance are relatively stable at room temperature and pressure, and it can be stored and transported safely. However, in case of high temperature, open flame or strong oxidant, it may cause chemical reactions and even lead to dangerous conditions, so it is necessary to strictly follow safety regulations when storing and using.
The above physical properties are of great significance to the application of (cyanodiethyl ester oxy) carbonylbenzyl in chemical production, organic synthesis and other fields. Practitioners need to carry out relevant operations scientifically and reasonably according to their characteristics.
What are the chemical properties of 4- (chlorodifluoromethoxy) nitrobenzene?
(Cyanodiethyloxo) benzylnaphthalene has unique chemical properties and is worth exploring.
This compound has certain stability and can maintain its own structure under common mild conditions. However, in case of strong oxidizing agents, such as permanganic acid, the benzyl part is easily oxidized, causing structural changes, or forming corresponding carboxylic acid derivatives. The cap is easily grabbed by oxidizing agents because the hydrogen atom on benzyl carbon has a certain activity.
In the nucleophilic substitution reaction, the benzyl position of (cyanodiethyloxo) benzylnaphthalene also exhibits activity. Due to the stability of benzyl carbocation, nucleophiles such as halogenated hydrocarbons can interact with them and replace them. For example, with iodomethane as a nucleophile, under appropriate alkali catalysis, the methyl group of iodomethane can replace the halogen atom on the benzyl group to obtain a new alkylation product.
Its cyanyl part is also not to be underestimated. Cyanyl has strong electron-absorbing properties and can affect the electron cloud distribution of molecules. This changes the polarity of the molecule, and the cyanyl group can be hydrolyzed under specific conditions and converted into a carboxyl group; or after reduction, it can be converted into an amino group, and various reaction paths can be derived.
Furthermore, the naphthalene ring part of (cyanodiethyloxo) benzylnaphthalene has a certain aromaticity due to its conjugate system. The naphthalene ring can undergo electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. Electrophilic reagents often attack the α position of the naphthalene ring, which is due to the relatively high electron cloud density of the α position and good reactivity. Taking bromination as an example, under the action of appropriate catalysts, bromine can selectively replace the hydrogen atom at the α position of the naphthalene ring, enriching the derivatization pathway of this compound.
What is the production method of 4- (chlorodifluoromethoxy) nitrobenzene?
The preparation method of 4 - (hydroxethoxycarbonyl) piperidinylnaphthalene is described in the ancient text of "Tiangong Kaiwu":
To make this 4 - (hydroxethoxycarbonyl) piperidinylnaphthalene, first take the naphthalene as the base, its properties are rigid and stable, and it is the bone of this product. If you use naphthalene into the kettle, the kettle should be clean and free of impurities. Then, take an appropriate amount of piperidine, which is soft and lively, and can be combined with naphthalene. Pour the piperidine slowly into the kettle containing naphthalene, during which the movement and static are appropriate, such as the intersection of yin and yang.
At this time, the contents of the kettle need to be boiled slowly, and the size of the fire is crucial. If the fire is big, things will be burnt, and if the fire is small, it should be slowed down. Looking at the heat, it is like a butcher to dissolve an ox, and you need to be well versed in it. When the naphthalene and piperidine gradually fuse and merge, it is an agent for adding hydroxyethyl oxycarbonyl. When this agent enters the kettle, if you are a little more connected, it will make all the things in the kettle change wonderfully.
After adding the agent, adjust the heat, or use martial fire to promote its response, or calm the fire to stabilize its state. In the meantime, stir frequently to make all the things uniform. The stirring device should be selected that is tough and does not disturb the things. Depending on the change of color and shape in the kettle, such as watching the clouds and gas in the sky, know the changes. When the things in the kettle are in the expected color state, then stop the fire.
Then pour out the contents of the kettle and filter out the impurities in a special device. The filter needs to be as fine as Luo, so that no impurities are left. The filtrate is condensed by the method of condensation, and the condensation environment should be cool and quiet. After condensation, the crude product of 4 - (hydroxyethyl oxycarbonyl) piperidinyl naphthalene can be obtained. The crude product still needs to be refined, by the method of sublimation and recrystallization, to remove its flaws and improve its purity. The process of refining, such as the process of carving jade into a tool, is carefully step by step to obtain the pure 4- (hydroxyethyl oxycarbonyl) piperidinyl naphthalene.
What are the precautions for using 4- (chlorodifluoromethoxy) nitrobenzene?
4 - (Hydroxyethoxycarbonyl) benzyl hydrazinocarboxylate should pay attention to the following things during use:
First, this material is chemically active. When storing, find a cool, dry and well-ventilated place, away from fire, heat and strong oxidants. Because the temperature is too high or contact with oxidants, it is very likely to cause chemical reactions, cause it to deteriorate and damage the use efficiency.
Second, when using, be sure to follow the standard operating procedures. When preparing suitable protective equipment, such as gloves, goggles and masks, to prevent it from coming into contact with the skin, eyes and respiratory tract. These substances may be irritating to the human body, or even potentially toxic. If you come into contact accidentally, you should immediately rinse with a large amount of water and seek medical attention as appropriate.
Third, in the chemical reaction system, its dosage and reaction conditions should be precisely controlled. Different reactions have specific requirements for their dosage, reaction temperature, time and solvent conditions. A slight poor pool may cause low reaction yield, or produce many side reactions, which affect the purity and quality of the product.
Fourth, after use, the disposal of residues and waste should not be ignored. It should be properly disposed of in accordance with relevant environmental regulations and laboratory regulations, and must not be discarded at will. Because it may cause pollution to the environment, it can only be handled in accordance with regulations to ensure the safety of the environment.
In short, when using 4- (hydroxyethoxycarbonyl) benzyl hydrazinocarboxylate, we should carefully observe all the points for attention, so that we can achieve the purpose of safe and efficient use and avoid many potential risks.