Linshang Chemical
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4-(Chloromethyl)-1,2-Dimethoxy Benzene
Linshang Chemical
|
HS Code |
644214 |
| Chemical Formula | C9H11ClO2 |
| Molar Mass | 186.635 g/mol |
| Appearance | Typically a colorless to light - yellow liquid |
| Boiling Point | Approximately 251 - 253 °C |
| Density | Data may vary, but around 1.15 - 1.2 g/cm³ |
| Solubility In Water | Insoluble in water |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, ethyl acetate |
| Flash Point | Data may vary, potentially around 100 - 110 °C |
| Odor | May have a characteristic, somewhat pungent odor |
| Reactivity | Reactive towards nucleophiles due to the presence of the chloromethyl group |
As an accredited 4-(Chloromethyl)-1,2-Dimethoxy Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottle packaging for 4-(chloromethyl)-1,2 - dimethoxy benzene. |
| Storage | 4-(Chloromethyl)-1,2 -dimethoxy benzene should be stored in a cool, dry, well - ventilated area away from heat sources, ignition sources, and incompatible substances. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Due to its potential reactivity, store it separately from oxidizing agents, bases, and nucleophiles to prevent unwanted reactions. |
| Shipping | 4-(Chloromethyl)-1,2 -dimethoxy benzene is shipped in well - sealed, corrosion - resistant containers. It follows strict chemical transportation regulations to ensure safety during transit, avoiding exposure to incompatible substances and extreme conditions. |
Competitive 4-(Chloromethyl)-1,2-Dimethoxy Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-(Chloromethyl)-1,2-Dimethoxy Benzene in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-(Chloromethyl)-1,2-Dimethoxy Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 4- (chloromethyl) -1,2-dimethoxy Benzene?
4- (chloromethyl) -1,2-dimethoxybenzene, an organic compound, has important uses in chemical industry, medicine and other fields.
In the chemical industry, it is an important intermediate in organic synthesis. It can react with various nucleophilic reagents, such as alcohols and amines, through nucleophilic substitution reactions, to construct a variety of organic compounds with different functions. For example, when reacted with alcohols, ether compounds can be formed, which are widely used in solvents, plasticizers, etc.; when reacted with amines, nitrogen-containing organic compounds can be prepared. Many nitrogen-containing compounds are key raw materials for the synthesis of dyes and pesticides. In addition, it can also participate in common reactions of halogenated hydrocarbons, such as coupling reactions with metal-organic reagents. This reaction is of great significance in building carbon-carbon bonds and helps to synthesize complex organic molecular structures. It is widely used in the field of new materials research and development.
In the field of medicine, 4- (chloromethyl) -1,2-dimethoxybenzene is also of great value. Due to its structural properties, it can be used as a lead compound for structural modification and optimization to develop new drugs. Some compounds synthesized from this starting material have been shown to have certain biological activities or potential therapeutic effects on specific diseases. For example, in the development of anti-tumor drugs, by modifying their structure, the synthesized derivatives may act on specific targets of tumor cells, interfering with the growth and proliferation of tumor cells, providing new ways and hope for conquering tumor diseases. Or in the development of drugs for the treatment of nervous system diseases, compounds synthesized based on this may regulate neurotransmitter transmission, improve nervous system function, and bring new opportunities for the treatment of related diseases.
In the chemical industry, it is an important intermediate in organic synthesis. It can react with various nucleophilic reagents, such as alcohols and amines, through nucleophilic substitution reactions, to construct a variety of organic compounds with different functions. For example, when reacted with alcohols, ether compounds can be formed, which are widely used in solvents, plasticizers, etc.; when reacted with amines, nitrogen-containing organic compounds can be prepared. Many nitrogen-containing compounds are key raw materials for the synthesis of dyes and pesticides. In addition, it can also participate in common reactions of halogenated hydrocarbons, such as coupling reactions with metal-organic reagents. This reaction is of great significance in building carbon-carbon bonds and helps to synthesize complex organic molecular structures. It is widely used in the field of new materials research and development.
In the field of medicine, 4- (chloromethyl) -1,2-dimethoxybenzene is also of great value. Due to its structural properties, it can be used as a lead compound for structural modification and optimization to develop new drugs. Some compounds synthesized from this starting material have been shown to have certain biological activities or potential therapeutic effects on specific diseases. For example, in the development of anti-tumor drugs, by modifying their structure, the synthesized derivatives may act on specific targets of tumor cells, interfering with the growth and proliferation of tumor cells, providing new ways and hope for conquering tumor diseases. Or in the development of drugs for the treatment of nervous system diseases, compounds synthesized based on this may regulate neurotransmitter transmission, improve nervous system function, and bring new opportunities for the treatment of related diseases.
What are the physical properties of 4- (chloromethyl) -1,2-dimethoxy Benzene
4- (chloromethyl) -1,2-dimethoxybenzene is one of the organic compounds. Its physical properties are very important and are related to the many uses and characteristics of this compound.
This compound is usually in a liquid state at room temperature and pressure, which makes it easier to mix and contact with other substances in some chemical reactions, and then participate in the reaction. Its color is often colorless to light yellow, with different purity or sensitivity to light and heat conditions, which may cause slight differences in color.
When it comes to odor, 4- (chloromethyl) -1,2-dimethoxybenzene has a special organic odor. However, this odor is not rich and pungent, but it should also be paid attention to because it may affect the human respiratory tract.
In terms of density, it has a certain density compared to water, and the density is slightly higher than that of water, which determines that it will be in the lower layer in the mixed system involving water and the compound.
Solubility is also one of the key physical properties. 4- (chloromethyl) -1,2-dimethoxybenzene is insoluble in water, but it is soluble in many organic solvents, such as ethanol, ether, etc. This solubility property makes it possible to extract, separate, or use it as a reaction medium by selecting suitable organic solvents in organic synthesis experiments or industrial production processes.
In addition, the melting point and boiling point cannot be ignored. Its melting point and boiling point are determined by intermolecular forces, relative molecular mass, and molecular structure. The specific melting point and boiling point data are of great significance for the storage, transportation, and setting of reaction conditions in chemical reactions. During storage, it is necessary to consider whether the state will change due to temperature changes according to the melting point; in chemical reactions, the boiling point is related to the temperature control of the reaction system to prevent the compound from volatilizing and escaping, which affects the reaction process and yield.
This compound is usually in a liquid state at room temperature and pressure, which makes it easier to mix and contact with other substances in some chemical reactions, and then participate in the reaction. Its color is often colorless to light yellow, with different purity or sensitivity to light and heat conditions, which may cause slight differences in color.
When it comes to odor, 4- (chloromethyl) -1,2-dimethoxybenzene has a special organic odor. However, this odor is not rich and pungent, but it should also be paid attention to because it may affect the human respiratory tract.
In terms of density, it has a certain density compared to water, and the density is slightly higher than that of water, which determines that it will be in the lower layer in the mixed system involving water and the compound.
Solubility is also one of the key physical properties. 4- (chloromethyl) -1,2-dimethoxybenzene is insoluble in water, but it is soluble in many organic solvents, such as ethanol, ether, etc. This solubility property makes it possible to extract, separate, or use it as a reaction medium by selecting suitable organic solvents in organic synthesis experiments or industrial production processes.
In addition, the melting point and boiling point cannot be ignored. Its melting point and boiling point are determined by intermolecular forces, relative molecular mass, and molecular structure. The specific melting point and boiling point data are of great significance for the storage, transportation, and setting of reaction conditions in chemical reactions. During storage, it is necessary to consider whether the state will change due to temperature changes according to the melting point; in chemical reactions, the boiling point is related to the temperature control of the reaction system to prevent the compound from volatilizing and escaping, which affects the reaction process and yield.
What are the synthesis methods of 4- (chloromethyl) -1,2-dimethoxy Benzene
The synthesis method of 4- (chloromethyl) -1,2-dimethoxybenzene has been known in ancient times, and this is a detailed description for you.
First, with 1,2-dimethoxybenzene as the starting material, the target product can be obtained by chloromethylation. This reaction requires specific reagents, such as paraformaldehyde and hydrogen chloride gas. Place 1,2-dimethoxybenzene in a suitable reaction vessel, add an appropriate amount of paraformaldehyde, and slowly introduce hydrogen chloride gas at a specific temperature. During this period, close attention must be paid to the reaction process, and temperature control is particularly critical. If the temperature is too high, side reactions will multiply and the purity of the product will be damaged; if the temperature is too low, the reaction will be slow and take a long time. After the reaction is completed, the pure 4- (chloromethyl) -1,2-dimethoxybenzene can be obtained by separation and purification methods, such as extraction, distillation, recrystallization, etc.
Second, other compounds can also be used as starters and prepared by multi-step reaction. First, a compound containing methoxy group is introduced into chloromethyl through a specific reaction, and then modified to construct the desired two-methoxy structure. Although this approach is complicated, if the reaction conditions of each step are suitable, the product with higher yield and purity can also be obtained.
Furthermore, the new catalytic synthesis method can be used for reference. The selection of a specific catalyst can effectively improve the reaction rate and selectivity. This catalyst is either a metal complex or an organic small molecule catalyst. Adding an appropriate amount of catalyst to the reaction system and optimizing the reaction conditions, such as temperature, solvent, and ratio of reactants, can make the reaction more efficient and green.
There are many methods for synthesizing 4- (chloromethyl) -1,2-dimethoxybenzene, each with advantages and disadvantages. In practical applications, when considering factors such as cost, yield, and purity according to specific needs, the optimal method should be selected.
First, with 1,2-dimethoxybenzene as the starting material, the target product can be obtained by chloromethylation. This reaction requires specific reagents, such as paraformaldehyde and hydrogen chloride gas. Place 1,2-dimethoxybenzene in a suitable reaction vessel, add an appropriate amount of paraformaldehyde, and slowly introduce hydrogen chloride gas at a specific temperature. During this period, close attention must be paid to the reaction process, and temperature control is particularly critical. If the temperature is too high, side reactions will multiply and the purity of the product will be damaged; if the temperature is too low, the reaction will be slow and take a long time. After the reaction is completed, the pure 4- (chloromethyl) -1,2-dimethoxybenzene can be obtained by separation and purification methods, such as extraction, distillation, recrystallization, etc.
Second, other compounds can also be used as starters and prepared by multi-step reaction. First, a compound containing methoxy group is introduced into chloromethyl through a specific reaction, and then modified to construct the desired two-methoxy structure. Although this approach is complicated, if the reaction conditions of each step are suitable, the product with higher yield and purity can also be obtained.
Furthermore, the new catalytic synthesis method can be used for reference. The selection of a specific catalyst can effectively improve the reaction rate and selectivity. This catalyst is either a metal complex or an organic small molecule catalyst. Adding an appropriate amount of catalyst to the reaction system and optimizing the reaction conditions, such as temperature, solvent, and ratio of reactants, can make the reaction more efficient and green.
There are many methods for synthesizing 4- (chloromethyl) -1,2-dimethoxybenzene, each with advantages and disadvantages. In practical applications, when considering factors such as cost, yield, and purity according to specific needs, the optimal method should be selected.
What are the precautions for 4- (chloromethyl) -1,2-dimethoxy Benzene during storage and transportation?
4- (chloromethyl) -1,2-dimethoxybenzene is also an organic compound. During storage and transportation, many matters need to be paid attention to.
First words storage, this compound should be stored in a cool and ventilated warehouse. Cover because of its nature or affected by temperature and humidity, high temperature or its chemical reaction activity changes, and humidity can cause deliquescence and other conditions, which will damage its quality. The temperature between warehouses should be carefully controlled, not too high, generally speaking, it is appropriate to maintain a suitable low temperature range. And should be kept away from fire and heat sources, because it is flammable or dangerous accidents caused by contact with fire sources. Furthermore, it needs to be stored separately from oxidizing agents, acids, alkalis, etc., to avoid mixed storage. Due to its active chemical properties, contact or violent reaction with their substances will endanger safety.
As for transportation, be sure to ensure that the packaging is complete and the loading is secure before transportation. Packaging materials must have good protective properties and can resist external physical impact and chemical erosion. During transportation, the speed of the vehicle should not be too fast, and the driving should be stable to prevent package damage caused by bumps and vibrations, and compound leakage. The escort personnel should also be familiar with its characteristics and emergency treatment methods. If there is an abnormality on the way, they can deal with it in time. And the transportation vehicle should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment for emergency needs. When loading and unloading, the operator should be light and light, and it is strictly forbidden to drop and heavy pressure to prevent damage to the packaging and affect the quality of the compound and transportation safety. In this way, 4- (chloromethyl) -1,2-dimethoxybenzene is safe and secure during storage and transportation.
First words storage, this compound should be stored in a cool and ventilated warehouse. Cover because of its nature or affected by temperature and humidity, high temperature or its chemical reaction activity changes, and humidity can cause deliquescence and other conditions, which will damage its quality. The temperature between warehouses should be carefully controlled, not too high, generally speaking, it is appropriate to maintain a suitable low temperature range. And should be kept away from fire and heat sources, because it is flammable or dangerous accidents caused by contact with fire sources. Furthermore, it needs to be stored separately from oxidizing agents, acids, alkalis, etc., to avoid mixed storage. Due to its active chemical properties, contact or violent reaction with their substances will endanger safety.
As for transportation, be sure to ensure that the packaging is complete and the loading is secure before transportation. Packaging materials must have good protective properties and can resist external physical impact and chemical erosion. During transportation, the speed of the vehicle should not be too fast, and the driving should be stable to prevent package damage caused by bumps and vibrations, and compound leakage. The escort personnel should also be familiar with its characteristics and emergency treatment methods. If there is an abnormality on the way, they can deal with it in time. And the transportation vehicle should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment for emergency needs. When loading and unloading, the operator should be light and light, and it is strictly forbidden to drop and heavy pressure to prevent damage to the packaging and affect the quality of the compound and transportation safety. In this way, 4- (chloromethyl) -1,2-dimethoxybenzene is safe and secure during storage and transportation.
What are the effects of 4- (chloromethyl) -1,2-dimethoxy Benzene on the environment and human health?
4- (Chloromethyl) -1,2-dimethoxybenzene has an impact on the environment and human health. This substance is toxic to a certain extent, and if released into the environment, it will be harmful to the ecosystem or health. It can cause water and soil pollution, and then harm aquatic organisms and terrestrial organisms. Aquatic organisms exposed to this substance may exhibit abnormal behavior, stunted growth, or even die. In terrestrial ecology, or harm plants, causing physiological dysfunction and stunted growth and development.
As far as human health is concerned, it can be harmful through respiratory tract, skin contact or accidental ingestion. It may irritate the respiratory tract, causing coughing, asthma, and even more serious respiratory diseases. If exposed to the skin, it may cause skin allergies, inflammation, and itching. Those who take it by mistake may damage the digestive system, and see nausea, vomiting, and abdominal pain. Long-term exposure to the environment containing this substance increases the risk of cancer, because it may be carcinogenic, damage human cell genes, cause abnormal cell proliferation, and cause cancer.
Therefore, when producing and using 4- (chloromethyl) -1,2-dimethoxybenzene, strict protective measures should be taken to avoid it polluting the environment and endangering human health. The disposal of waste from this substance must also follow strict regulations to ensure the ecological environment and human well-being.
As far as human health is concerned, it can be harmful through respiratory tract, skin contact or accidental ingestion. It may irritate the respiratory tract, causing coughing, asthma, and even more serious respiratory diseases. If exposed to the skin, it may cause skin allergies, inflammation, and itching. Those who take it by mistake may damage the digestive system, and see nausea, vomiting, and abdominal pain. Long-term exposure to the environment containing this substance increases the risk of cancer, because it may be carcinogenic, damage human cell genes, cause abnormal cell proliferation, and cause cancer.
Therefore, when producing and using 4- (chloromethyl) -1,2-dimethoxybenzene, strict protective measures should be taken to avoid it polluting the environment and endangering human health. The disposal of waste from this substance must also follow strict regulations to ensure the ecological environment and human well-being.
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