Linshang Chemical
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4-Iodo-1-Chloro-2-(4-Ethoxybenzyl)Benzene
Linshang Chemical
|
HS Code |
620631 |
| Chemical Formula | C15H14ClIO |
| Molecular Weight | 376.63 |
| Appearance | Typically a solid (physical state may vary based on conditions) |
| Solubility In Water | Expected to be low (organic compound with non - polar groups) |
| Solubility In Organic Solvents | Likely soluble in common organic solvents like ethanol, dichloromethane due to its organic nature |
| Odor | No information available (odor characteristics are often determined experimentally) |
| Stability | Stability can be affected by light, heat, and air; might be subject to decomposition over time |
As an accredited 4-Iodo-1-Chloro-2-(4-Ethoxybenzyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 4 - iodo - 1 - chloro - 2 - (4 - ethoxybenzyl)benzene in sealed chemical - grade container. |
| Storage | Store 4 - iodo - 1 - chloro - 2 - (4 - ethoxybenzyl)benzene in a cool, dry place away from direct sunlight. Keep it in a well - sealed container, preferably made of glass or a suitable chemical - resistant plastic. Isolate it from sources of heat, ignition, and incompatible substances such as strong oxidizing agents to prevent potential reactions and ensure its stability over time. |
| Shipping | 4 - iodo - 1 - chloro - 2 - (4 - ethoxybenzyl)benzene is shipped in sealed, corrosion - resistant containers. Special handling is ensured to prevent exposure, with strict compliance to chemical shipping regulations for safe transportation. |
Competitive 4-Iodo-1-Chloro-2-(4-Ethoxybenzyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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What is the chemical structure of 4-iodo-1-chloro-2- (4-ethoxybenzyl) benzene?
4 - iodo - 1 - chloro - 2 - (4 - ethoxybenzyl) benzene, has the name of a benzene compound. If you want to know its chemical composition, you can analyze it by name.
"4 - iodo", there is an iodine atom at the 4th position of benzene. One of the iodine atoms, one of the elements, which occupies a specific position of benzene in this compound.
"1 - chloro", shows that there is a chlorine atom at the 1st position of benzene. Chloroisin, whose iodine is co-attached to benzene, determines one of the basic frameworks of this compound.
"2 - (4 - ethoxybenzyl) ", or " Benzyl ", benzyl is also, that is, benzyl, -CH -2 - benzene phase. And the benzyl group has" ethoxy "group in the fourth position of benzyl," ethoxy "and ethoxy group, -O - CH -2 - CH. This whole group is located in the second position of the original benzene.
In summary, this compound has a chlorine atom in the parent nucleus of benzene, an iodine atom in the fourth position, and a 4-ethoxy benzyl group in the second position. The solution is as follows: first, there is a benzene, and the chlorine atom at the first position is in the phase of benzene, and the iodine atom at the fourth position is also in the phase of benzene; at the second position, there is first a phase of benzene - CH 2O - (one part of benzyl), and this - CH 2O - there is another benzene at the other end, and this benzene has a phase of - O - CH 2O - CH < unk > (ethoxy). In this way, it is formed into a 4 - iodo - 1 - chloro - 2 - (4 - ethoxybenzyl) benzene.
"4 - iodo", there is an iodine atom at the 4th position of benzene. One of the iodine atoms, one of the elements, which occupies a specific position of benzene in this compound.
"1 - chloro", shows that there is a chlorine atom at the 1st position of benzene. Chloroisin, whose iodine is co-attached to benzene, determines one of the basic frameworks of this compound.
"2 - (4 - ethoxybenzyl) ", or " Benzyl ", benzyl is also, that is, benzyl, -CH -2 - benzene phase. And the benzyl group has" ethoxy "group in the fourth position of benzyl," ethoxy "and ethoxy group, -O - CH -2 - CH. This whole group is located in the second position of the original benzene.
In summary, this compound has a chlorine atom in the parent nucleus of benzene, an iodine atom in the fourth position, and a 4-ethoxy benzyl group in the second position. The solution is as follows: first, there is a benzene, and the chlorine atom at the first position is in the phase of benzene, and the iodine atom at the fourth position is also in the phase of benzene; at the second position, there is first a phase of benzene - CH 2O - (one part of benzyl), and this - CH 2O - there is another benzene at the other end, and this benzene has a phase of - O - CH 2O - CH < unk > (ethoxy). In this way, it is formed into a 4 - iodo - 1 - chloro - 2 - (4 - ethoxybenzyl) benzene.
What are the main uses of 4-iodo-1-chloro-2- (4-ethoxybenzyl) benzene?
4-Iodo-1-chloro-2 - (4-ethoxybenzyl) benzene, or 4-iodo-1-chloro-2 - (4-ethoxybenzyl) benzene in Chinese. The use of this substance is quite critical in chemical synthesis.
First, it can be used as an intermediary in organic synthesis. The art of organic synthesis, in order to make complex organic compounds with unique properties, often relies on such intermediates. With a carefully designed reaction path, this substance is used as the starting material, and it can be skillfully converted through many reactions such as halogenation, substitution, and coupling to obtain the target product. This is especially commonly used in the creation of new drug molecules and key structural units of functional materials.
Second, in the field of medicinal chemistry, it may have potential value. Drug research and development often requires the exploration of active compounds, and through structural modification and optimization, new drugs with good efficacy and small side effects can be obtained. The unique structure of this compound may endow it with specific biological activities, or it can interact with specific targets in organisms, providing an important starting template for the development of new drugs. After in-depth pharmacological research and structural optimization, new therapeutic drugs may be conceived.
Third, in the field of materials science, it is also promising. With the advance of science and technology, the need for materials with special properties is increasing. 4-Iodine-1-chloro-2 - (4-ethoxybenzyl) benzene can be introduced into the main chain or side chain of polymer materials through specific reactions to change the electrical, optical and thermal properties of the materials, and prepare materials with special photoelectric properties, such as organic Light Emitting Diode materials, solar cell materials, etc., which contribute to the development of material innovation.
First, it can be used as an intermediary in organic synthesis. The art of organic synthesis, in order to make complex organic compounds with unique properties, often relies on such intermediates. With a carefully designed reaction path, this substance is used as the starting material, and it can be skillfully converted through many reactions such as halogenation, substitution, and coupling to obtain the target product. This is especially commonly used in the creation of new drug molecules and key structural units of functional materials.
Second, in the field of medicinal chemistry, it may have potential value. Drug research and development often requires the exploration of active compounds, and through structural modification and optimization, new drugs with good efficacy and small side effects can be obtained. The unique structure of this compound may endow it with specific biological activities, or it can interact with specific targets in organisms, providing an important starting template for the development of new drugs. After in-depth pharmacological research and structural optimization, new therapeutic drugs may be conceived.
Third, in the field of materials science, it is also promising. With the advance of science and technology, the need for materials with special properties is increasing. 4-Iodine-1-chloro-2 - (4-ethoxybenzyl) benzene can be introduced into the main chain or side chain of polymer materials through specific reactions to change the electrical, optical and thermal properties of the materials, and prepare materials with special photoelectric properties, such as organic Light Emitting Diode materials, solar cell materials, etc., which contribute to the development of material innovation.
What are the physical properties of 4-iodo-1-chloro-2- (4-ethoxybenzyl) benzene?
4 - iodo - 1 - chloro - 2 - (4 - ethoxybenzyl) benzene, Chinese name or 4 - iodo - 1 - chloro - 2 - (4 - ethoxybenzyl) benzene. The physical properties of this substance are important, and it can be used to clarify its characteristics, which is used in the field of diversity.
The first word is that its appearance is often solid, but it has a shape. It may vary depending on the method and degree. Or it is crystalline, the crystal shape is complete, and it has a certain shape. Or it is powder.
Its fusion is also one of the important physical properties. If the temperature of the product is high, the melting value can be obtained. This value is important for determining the quality of the product and judging its temperature. If the temperature of the product is high, the melting temperature is in a narrow range, and the melting temperature of the product is similar. If the melting temperature is high, or the value of the product has a large deviation, it is implied that the product or contains a temperature.
The boiling temperature should not be ignored. The determination of the boiling temperature of this product can help researchers understand its melting characteristics. Under certain conditions, it is difficult to boil until the boiling temperature, and the product is shipped from the liquid. This property is very important in the preparation process. It can be divided into other materials by methods such as steaming, depending on the boiling temperature.
The solubility is also physical. In some soluble solutions, such as ethanol, ether, dichloromethane, etc., their solubility may be different. In some soluble solutions, they may have good solubility and can form homogeneous solutions; in non-soluble solutions, solubility may be poor. This solubility characteristic makes it difficult to reduce the solubility of anti-reactive components and anti-reactive media.
The density is also one of the physical properties of this object. The density is determined, and the amount of reactive components can be known. This property is important in terms of material ratio and solution distribution, etc., which can help researchers to control the reactive components and improve the reproducibility.
In addition, its refractive index also has a research value. Refractive index reflects the refractive ability of light, molecules and aggregates. Determining the refractive index of this substance can provide information on its molecular value and degree, which may be useful in the research field of optical materials and other phases.
The first word is that its appearance is often solid, but it has a shape. It may vary depending on the method and degree. Or it is crystalline, the crystal shape is complete, and it has a certain shape. Or it is powder.
Its fusion is also one of the important physical properties. If the temperature of the product is high, the melting value can be obtained. This value is important for determining the quality of the product and judging its temperature. If the temperature of the product is high, the melting temperature is in a narrow range, and the melting temperature of the product is similar. If the melting temperature is high, or the value of the product has a large deviation, it is implied that the product or contains a temperature.
The boiling temperature should not be ignored. The determination of the boiling temperature of this product can help researchers understand its melting characteristics. Under certain conditions, it is difficult to boil until the boiling temperature, and the product is shipped from the liquid. This property is very important in the preparation process. It can be divided into other materials by methods such as steaming, depending on the boiling temperature.
The solubility is also physical. In some soluble solutions, such as ethanol, ether, dichloromethane, etc., their solubility may be different. In some soluble solutions, they may have good solubility and can form homogeneous solutions; in non-soluble solutions, solubility may be poor. This solubility characteristic makes it difficult to reduce the solubility of anti-reactive components and anti-reactive media.
The density is also one of the physical properties of this object. The density is determined, and the amount of reactive components can be known. This property is important in terms of material ratio and solution distribution, etc., which can help researchers to control the reactive components and improve the reproducibility.
In addition, its refractive index also has a research value. Refractive index reflects the refractive ability of light, molecules and aggregates. Determining the refractive index of this substance can provide information on its molecular value and degree, which may be useful in the research field of optical materials and other phases.
What is the synthesis method of 4-iodo-1-chloro-2- (4-ethoxybenzyl) benzene?
To prepare 4-iodine-1-chloro-2 - (4-ethoxybenzyl) benzene, the following methods can be used:
Take 4-ethoxybenzyl alcohol first, and use a suitable reagent, such as sulfinyl chloride. Under suitable reaction conditions, such as heating and chlorination in an inert solvent, the alcohol hydroxyl group is converted into a chlorine atom to obtain 4-ethoxybenzyl chloride. During this reaction process, close attention should be paid to the reaction temperature and time. If the temperature is too high or the time is too long, side reactions may occur, resulting in impure products.
Following the preparation of 1-chloro-2-iodobenzene, anhydrous tetrahydrofuran is used as a solvent, and magnesium chips are added to initiate the Grignard reaction to generate the corresponding Grignard reagent. This step requires strict anhydrous and anaerobic conditions of the reaction system, otherwise the Grignard reagent is easy to react with water or oxygen and fail.
After the Grignard reagent is prepared, the tetrahydrofuran solution of 4-ethoxybenzyl chloride prepared above is slowly added dropwise at a low temperature and stirred state. After the dropwise addition is completed, the temperature is raised to a suitable temperature to allow the reaction to proceed fully. During this nucleophilic substitution reaction, the control of the rate of stirring and temperature is extremely critical, which is related to the process of the reaction After the reaction is completed, the reaction is quenched with ammonium chloride saturated solution, and then the product is purified by conventional extraction, washing, drying, column chromatography and other means. During extraction, select the right organic solvent, wash to remove impurities, dry to remove water thoroughly, column chromatography according to the polarity difference between the product and the impurity, fine separation, and pure 4-iodine-1-chloro-2 - (4-ethoxybenzyl) benzene. The whole synthesis process, the reaction conditions and operation details of each step have a great impact on the quality and yield of the product, which needs to be strictly controlled.
Take 4-ethoxybenzyl alcohol first, and use a suitable reagent, such as sulfinyl chloride. Under suitable reaction conditions, such as heating and chlorination in an inert solvent, the alcohol hydroxyl group is converted into a chlorine atom to obtain 4-ethoxybenzyl chloride. During this reaction process, close attention should be paid to the reaction temperature and time. If the temperature is too high or the time is too long, side reactions may occur, resulting in impure products.
Following the preparation of 1-chloro-2-iodobenzene, anhydrous tetrahydrofuran is used as a solvent, and magnesium chips are added to initiate the Grignard reaction to generate the corresponding Grignard reagent. This step requires strict anhydrous and anaerobic conditions of the reaction system, otherwise the Grignard reagent is easy to react with water or oxygen and fail.
After the Grignard reagent is prepared, the tetrahydrofuran solution of 4-ethoxybenzyl chloride prepared above is slowly added dropwise at a low temperature and stirred state. After the dropwise addition is completed, the temperature is raised to a suitable temperature to allow the reaction to proceed fully. During this nucleophilic substitution reaction, the control of the rate of stirring and temperature is extremely critical, which is related to the process of the reaction After the reaction is completed, the reaction is quenched with ammonium chloride saturated solution, and then the product is purified by conventional extraction, washing, drying, column chromatography and other means. During extraction, select the right organic solvent, wash to remove impurities, dry to remove water thoroughly, column chromatography according to the polarity difference between the product and the impurity, fine separation, and pure 4-iodine-1-chloro-2 - (4-ethoxybenzyl) benzene. The whole synthesis process, the reaction conditions and operation details of each step have a great impact on the quality and yield of the product, which needs to be strictly controlled.
What are the safety precautions for 4-iodo-1-chloro-2- (4-ethoxybenzyl) benzene?
4-Iodo-1-chloro-2- (4-ethoxybenzyl) benzene is an organic compound. When using and handling this substance, many safety precautions must be paid attention to.
Bear the brunt because it is a chemical substance and may be potentially harmful to the human body. Touch the skin can cause irritation, be sure to avoid direct contact. When operating, wear protective gloves properly. The material should be able to effectively resist the chemical, such as nitrile gloves. If you accidentally come into contact with the skin, you should immediately rinse with plenty of water. The rinsing time should be not less than 15 minutes, and then according to the specific situation, or seek medical treatment.
Its volatile gaseous substances may irritate the respiratory tract. In the operating environment, it is necessary to ensure good ventilation, and it is best to equip a fume hood to facilitate the timely discharge of volatile gases. If working without a fume hood, appropriate respiratory protective equipment, such as a gas mask, should be worn, and a suitable filter box should be selected according to the actual environment and the degree of harm.
This compound is also irritating to the eyes, and may cause damage in severe cases. During operation, be sure to wear protective glasses or face screens to build reliable protection for the eyes. Once accidentally splashed into the eyes, the eyelids should be opened immediately, rinsed with a large amount of flowing water or normal saline, and the eyeballs should be turned when rinsing to ensure thorough cleaning. After rinsing, seek medical attention quickly.
Furthermore, the compound may be flammable. When storing, keep away from fire and heat sources, store in a cool, dry and ventilated place, and avoid direct sunlight. At the same time, the storage area should be equipped with suitable fire extinguishing equipment, such as dry powder fire extinguishers, carbon dioxide fire extinguishers, etc., for emergencies.
In addition, use an appropriate amount during operation to avoid unnecessary waste. After the experiment is completed, the remaining substances and waste should be followed by relevant regulations, properly disposed of, and must not be discarded at will to prevent pollution to the environment. During the entire operation and use process, the operator should have a detailed understanding of the safety data table of the substance, be familiar with emergency treatment measures, and ensure their own safety and environmental safety.
Bear the brunt because it is a chemical substance and may be potentially harmful to the human body. Touch the skin can cause irritation, be sure to avoid direct contact. When operating, wear protective gloves properly. The material should be able to effectively resist the chemical, such as nitrile gloves. If you accidentally come into contact with the skin, you should immediately rinse with plenty of water. The rinsing time should be not less than 15 minutes, and then according to the specific situation, or seek medical treatment.
Its volatile gaseous substances may irritate the respiratory tract. In the operating environment, it is necessary to ensure good ventilation, and it is best to equip a fume hood to facilitate the timely discharge of volatile gases. If working without a fume hood, appropriate respiratory protective equipment, such as a gas mask, should be worn, and a suitable filter box should be selected according to the actual environment and the degree of harm.
This compound is also irritating to the eyes, and may cause damage in severe cases. During operation, be sure to wear protective glasses or face screens to build reliable protection for the eyes. Once accidentally splashed into the eyes, the eyelids should be opened immediately, rinsed with a large amount of flowing water or normal saline, and the eyeballs should be turned when rinsing to ensure thorough cleaning. After rinsing, seek medical attention quickly.
Furthermore, the compound may be flammable. When storing, keep away from fire and heat sources, store in a cool, dry and ventilated place, and avoid direct sunlight. At the same time, the storage area should be equipped with suitable fire extinguishing equipment, such as dry powder fire extinguishers, carbon dioxide fire extinguishers, etc., for emergencies.
In addition, use an appropriate amount during operation to avoid unnecessary waste. After the experiment is completed, the remaining substances and waste should be followed by relevant regulations, properly disposed of, and must not be discarded at will to prevent pollution to the environment. During the entire operation and use process, the operator should have a detailed understanding of the safety data table of the substance, be familiar with emergency treatment measures, and ensure their own safety and environmental safety.
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