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4-Nitrochlorobenzene-2-Sulfonic Acid
Linshang Chemical
|
HS Code |
654207 |
| Chemical Formula | C6H4ClNO5S |
| Molar Mass | 237.62 g/mol |
| Appearance | White to off - white crystalline solid |
| Solubility In Water | Slightly soluble |
| Melting Point | 125 - 127 °C |
| Density | 1.72 g/cm³ |
| Ph Aqueous Solution | Acidic |
| Stability | Stable under normal conditions |
| Hazard Class | Irritant to skin, eyes and respiratory system |
As an accredited 4-Nitrochlorobenzene-2-Sulfonic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500 - gram pack of 4 - nitrochlorobenzene - 2 - sulfonic acid in sealed chemical - grade container. |
| Storage | 4 - nitrochlorobenzene - 2 - sulfonic acid should be stored in a cool, dry, well - ventilated area, away from heat sources and direct sunlight. Keep it in a tightly closed container to prevent moisture absorption and contact with air. Store it separately from oxidizing agents, reducing agents, and bases to avoid potential chemical reactions. |
| Shipping | 4 - nitrochlorobenzene - 2 - sulfonic acid should be shipped in tightly - sealed containers, following regulations for hazardous chemicals. Ensure proper labeling and transport in a way that prevents leakage, with measures to handle potential spills safely. |
Competitive 4-Nitrochlorobenzene-2-Sulfonic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Nitrochlorobenzene-2-Sulfonic Acid in China?
As a trusted 4-Nitrochlorobenzene-2-Sulfonic Acid manufacturer, we deliver:
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Nitrochlorobenzene-2-Sulfonic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4-nitrochlorobenzene-2-sulfonic Acid?
4-Nitrochlorobenzene-2-sulfonic acid is an important category of organic compounds. Its main uses are diverse and pervasive in various fields of chemical industry.
First, in the process of dye preparation, this compound is the most important. Due to its unique structure, it can be used as a key intermediate. After a series of delicate chemical reactions, it can be converted into many dyes with bright colors and excellent performance. The dyes produced from it are widely used in textile, printing and dyeing industries to make fabrics colorful, and have good light resistance and washable fastness, which greatly meets the needs of the world for the beauty and durability of fabrics.
Second, in the field of pharmaceutical synthesis, 4-nitrochlorobenzene-2-sulfonic acid is also indispensable. It can participate in the construction of a variety of drug molecules, and by virtue of its own chemical activity, it lays the foundation for the synthesis of drugs with specific structures and functions. The preparation of many antibacterial, anti-inflammatory and other drugs often relies on this compound as the starting material. After fine synthesis steps, it can finally obtain effective pharmaceutical products to solve the suffering of human diseases.
Third, in the creation of pesticides, this substance has also emerged. It can be used as an important component of synthetic pesticides. After ingenious design and reaction, pesticides with high insecticidal, weeding or bactericidal properties can be prepared. In agricultural production, such pesticides help crops resist pest attacks, improve crop yield and quality, and are of great significance to ensuring food security.
In addition, 4-nitrochlorobenzene-2-sulfonic acid also plays an important role in the preparation of some special chemicals. For example, when synthesizing some functional materials, it can be used as a modifier or additive to endow the materials with unique physical and chemical properties to meet the needs of special materials in fields such as electronics and optics. In short, this compound plays an important role in many aspects of the chemical industry, promoting the progress and development of various related industries.
First, in the process of dye preparation, this compound is the most important. Due to its unique structure, it can be used as a key intermediate. After a series of delicate chemical reactions, it can be converted into many dyes with bright colors and excellent performance. The dyes produced from it are widely used in textile, printing and dyeing industries to make fabrics colorful, and have good light resistance and washable fastness, which greatly meets the needs of the world for the beauty and durability of fabrics.
Second, in the field of pharmaceutical synthesis, 4-nitrochlorobenzene-2-sulfonic acid is also indispensable. It can participate in the construction of a variety of drug molecules, and by virtue of its own chemical activity, it lays the foundation for the synthesis of drugs with specific structures and functions. The preparation of many antibacterial, anti-inflammatory and other drugs often relies on this compound as the starting material. After fine synthesis steps, it can finally obtain effective pharmaceutical products to solve the suffering of human diseases.
Third, in the creation of pesticides, this substance has also emerged. It can be used as an important component of synthetic pesticides. After ingenious design and reaction, pesticides with high insecticidal, weeding or bactericidal properties can be prepared. In agricultural production, such pesticides help crops resist pest attacks, improve crop yield and quality, and are of great significance to ensuring food security.
In addition, 4-nitrochlorobenzene-2-sulfonic acid also plays an important role in the preparation of some special chemicals. For example, when synthesizing some functional materials, it can be used as a modifier or additive to endow the materials with unique physical and chemical properties to meet the needs of special materials in fields such as electronics and optics. In short, this compound plays an important role in many aspects of the chemical industry, promoting the progress and development of various related industries.
What are the physical properties of 4-nitrochlorobenzene-2-sulfonic Acid?
4-Nitrochlorobenzene-2-sulfonic acid is a class of organic compounds. Its physical properties are quite unique, let me tell them one by one.
Looking at its appearance, it is often in the form of crystalline or powder, and the color is mostly white to light yellow. The appearance of this color is caused by the interaction of atoms in the molecular structure. Its melting point is relatively high, and at a certain temperature, it begins to melt from solid to liquid. This characteristic makes it stable under specific conditions, which is conducive to storage and transportation.
In terms of solubility, 4-nitrochlorobenzene-2-sulfonic acid has limited solubility in water, but it can exhibit better solubility in some organic solvents, such as alcohols and ethers. The root of this difference lies in the interaction of both hydrophilic sulfonic acid groups and hydrophobic nitro and chlorobenzene groups in its molecular structure, resulting in different solubility in different solvents.
The density of 4-nitrochlorobenzene-2-sulfonic acid is higher than that of water, and it will naturally settle when placed in water. Its stability is also worthy of attention. When it is at room temperature and pressure without special chemical environment, the substance is relatively stable. However, in case of extreme conditions such as high temperature, strong acid, and strong alkali, the molecular structure may change, triggering a chemical reaction.
In addition, when 4-nitrochlorobenzene-2-sulfonic acid is in the solid state, the texture is more delicate, the touch is smooth, and because of its certain crystallinity, the crystal shape is regular and has a certain gloss. Its smell is weak, and it is almost invisible without a close smell.
In summary, the physical properties of 4-nitrochlorobenzene-2-sulfonic acid are determined by its molecular structure, and its application in many fields such as chemical industry is also closely related to its unique physical properties.
Looking at its appearance, it is often in the form of crystalline or powder, and the color is mostly white to light yellow. The appearance of this color is caused by the interaction of atoms in the molecular structure. Its melting point is relatively high, and at a certain temperature, it begins to melt from solid to liquid. This characteristic makes it stable under specific conditions, which is conducive to storage and transportation.
In terms of solubility, 4-nitrochlorobenzene-2-sulfonic acid has limited solubility in water, but it can exhibit better solubility in some organic solvents, such as alcohols and ethers. The root of this difference lies in the interaction of both hydrophilic sulfonic acid groups and hydrophobic nitro and chlorobenzene groups in its molecular structure, resulting in different solubility in different solvents.
The density of 4-nitrochlorobenzene-2-sulfonic acid is higher than that of water, and it will naturally settle when placed in water. Its stability is also worthy of attention. When it is at room temperature and pressure without special chemical environment, the substance is relatively stable. However, in case of extreme conditions such as high temperature, strong acid, and strong alkali, the molecular structure may change, triggering a chemical reaction.
In addition, when 4-nitrochlorobenzene-2-sulfonic acid is in the solid state, the texture is more delicate, the touch is smooth, and because of its certain crystallinity, the crystal shape is regular and has a certain gloss. Its smell is weak, and it is almost invisible without a close smell.
In summary, the physical properties of 4-nitrochlorobenzene-2-sulfonic acid are determined by its molecular structure, and its application in many fields such as chemical industry is also closely related to its unique physical properties.
What are the chemical properties of 4-nitrochlorobenzene-2-sulfonic Acid?
4-Nitrochlorobenzene-2-sulfonic acid, this is an organic compound. Its chemical properties are unique and very important.
Let's talk about its acidity first. The sulfonic acid group is a strong acidic group, which gives the compound significant acidity. In water, it is easy to ionize hydrogen ions, showing the general properties of acids. For example, it can neutralize with bases to generate corresponding salts and water.
Let's talk about its substitution reaction. The chlorine atom on the benzene ring changes its activity due to the influence of nitro and sulfonic acid groups. The nitro group is a strong electron-absorbing group, and the sulfonic acid group also has an electron-withdrawing effect, which makes the electron cloud density at the location of the chlorine atom lower, and it is more susceptible to attack by nucleophiles, resulting in nucleophil For example, when co-heated with sodium hydroxide solution, chlorine atoms can be replaced by hydroxyl groups to form 4-nitrophenol-2-sulfonic acid.
In addition, nitro groups can also undergo reduction reactions. Under suitable conditions, such as using iron powder and hydrochloric acid as reducing agents, nitro groups can be reduced to amino groups to form 4-aminochlorobenzene-2-sulfonic acid. This product has a wide range of uses in dye synthesis and other fields.
In terms of stability, the existence of a conjugated system in the molecule enhances the stability to a certain extent. However, the strong electron-absorbing properties of nitro and sulfonic acid groups reduce the electron cloud density of the benzene ring. Under certain conditions, some reactions involving structural changes of the benzene ring may occur. In conclusion, the chemical properties of 4-nitrochlorobenzene-2-sulfonic acid are rich and diverse, which is of great significance in the field of organic synthesis.
Let's talk about its acidity first. The sulfonic acid group is a strong acidic group, which gives the compound significant acidity. In water, it is easy to ionize hydrogen ions, showing the general properties of acids. For example, it can neutralize with bases to generate corresponding salts and water.
Let's talk about its substitution reaction. The chlorine atom on the benzene ring changes its activity due to the influence of nitro and sulfonic acid groups. The nitro group is a strong electron-absorbing group, and the sulfonic acid group also has an electron-withdrawing effect, which makes the electron cloud density at the location of the chlorine atom lower, and it is more susceptible to attack by nucleophiles, resulting in nucleophil For example, when co-heated with sodium hydroxide solution, chlorine atoms can be replaced by hydroxyl groups to form 4-nitrophenol-2-sulfonic acid.
In addition, nitro groups can also undergo reduction reactions. Under suitable conditions, such as using iron powder and hydrochloric acid as reducing agents, nitro groups can be reduced to amino groups to form 4-aminochlorobenzene-2-sulfonic acid. This product has a wide range of uses in dye synthesis and other fields.
In terms of stability, the existence of a conjugated system in the molecule enhances the stability to a certain extent. However, the strong electron-absorbing properties of nitro and sulfonic acid groups reduce the electron cloud density of the benzene ring. Under certain conditions, some reactions involving structural changes of the benzene ring may occur. In conclusion, the chemical properties of 4-nitrochlorobenzene-2-sulfonic acid are rich and diverse, which is of great significance in the field of organic synthesis.
What is the preparation method of 4-nitrochlorobenzene-2-sulfonic Acid?
The method of preparing 4-nitrochlorobenzene-2-sulfonic acid used to follow the sulfonation reaction in the past. The first chlorobenzene is taken as the starting material, and an appropriate amount of fuming sulfuric acid or concentrated sulfuric acid is added to an appropriate reactor. Both of these have strong sulfonation properties and can be used for the reaction to supply sulfonic acid groups.
During the reaction, the temperature should be carefully controlled. Usually at a lower temperature, the sulfuric acid interacts with the chlorobenzene gradually, initially or between 30 and 50 degrees Celsius. At this time, the protons of the sulfuric acid interact with the benzene ring of the chlorobenzene to form an active intermediate. Later, it is slowly heated to 80 to 120 degrees Celsius to promote the positioning of the sulfonic acid based on the specific position of Due to the combined influence of chlorine as an ortho-para-site group and nitro as an meta-site group, the sulfonic acid group is more likely to enter the ortho-site of chlorine and the para-site of nitro group, so 4-nitrochlorobenzene-2-sulfonic acid is obtained.
During the reaction process, or use a stirring device to mix the reactants evenly to ensure a uniform reaction. And the temperature must be closely monitored with a thermometer to avoid side reactions caused by runaway temperature, such as the release of polysulfonation products, or the destruction of the benzene ring structure.
After the reaction is completed, pour the reaction mixture into ice water and quench it. This can cause 4-nitrochlorobenzene-2-sulfonic acid to precipitate in solid form. After filtration, the solid product is separated. Then wash with water or a suitable organic solvent to remove impurities. Finally, through a drying step, pure 4-nitrochlorobenzene-2-sulfonic acid can be obtained.
There is also an improved method to add specific catalysts to the reaction system, such as some metal salts or Lewis acids. This can reduce the activation energy of the reaction, shrink the reaction time, and improve the reaction yield. However, when choosing a catalyst, it is necessary to consider its effect on the selectivity of the reaction, so that 4-nitrochlorobenzene-2-sulfonic acid is still mainly produced.
During the reaction, the temperature should be carefully controlled. Usually at a lower temperature, the sulfuric acid interacts with the chlorobenzene gradually, initially or between 30 and 50 degrees Celsius. At this time, the protons of the sulfuric acid interact with the benzene ring of the chlorobenzene to form an active intermediate. Later, it is slowly heated to 80 to 120 degrees Celsius to promote the positioning of the sulfonic acid based on the specific position of Due to the combined influence of chlorine as an ortho-para-site group and nitro as an meta-site group, the sulfonic acid group is more likely to enter the ortho-site of chlorine and the para-site of nitro group, so 4-nitrochlorobenzene-2-sulfonic acid is obtained.
During the reaction process, or use a stirring device to mix the reactants evenly to ensure a uniform reaction. And the temperature must be closely monitored with a thermometer to avoid side reactions caused by runaway temperature, such as the release of polysulfonation products, or the destruction of the benzene ring structure.
After the reaction is completed, pour the reaction mixture into ice water and quench it. This can cause 4-nitrochlorobenzene-2-sulfonic acid to precipitate in solid form. After filtration, the solid product is separated. Then wash with water or a suitable organic solvent to remove impurities. Finally, through a drying step, pure 4-nitrochlorobenzene-2-sulfonic acid can be obtained.
There is also an improved method to add specific catalysts to the reaction system, such as some metal salts or Lewis acids. This can reduce the activation energy of the reaction, shrink the reaction time, and improve the reaction yield. However, when choosing a catalyst, it is necessary to consider its effect on the selectivity of the reaction, so that 4-nitrochlorobenzene-2-sulfonic acid is still mainly produced.
What to pay attention to when storing and transporting 4-nitrochlorobenzene-2-sulfonic Acid
4-Nitrochlorobenzene-2-sulfonic acid is commonly used in chemical industry. When storing and transporting, many matters must not be ignored.
First words storage, must choose a cool, dry and well-ventilated place. This is because if the material is exposed to high temperature and humidity, it is prone to qualitative change. In case of heat, it may decompose due to heat, resulting in changes in performance, and decomposition products or dangerous. The humidity of the warehouse should be controlled within a moderate range to prevent moisture decomposition. It must also be stored in isolation from oxidizing agents, alkalis, etc. Due to its active chemical properties, contact with them may cause violent reactions, even the risk of explosion.
As for transportation, make sure that the packaging is intact and tightly sealed. During transportation, protect against sun exposure, rain and high temperature. When loading and unloading, pack lightly and unload lightly, avoid bumping and heavy pressure, so as to avoid package damage and material leakage. Transportation vehicles should be equipped with corresponding fire equipment and leakage emergency treatment equipment. If the package is damaged or the material leaks during transportation, it should be properly handled according to the emergency treatment method as soon as possible to prevent the spread of hazards.
In short, the storage and transportation of 4-nitrochlorobenzene-2-sulfonic acid must be handled with caution and in accordance with regulations to ensure safety and avoid accidents.
First words storage, must choose a cool, dry and well-ventilated place. This is because if the material is exposed to high temperature and humidity, it is prone to qualitative change. In case of heat, it may decompose due to heat, resulting in changes in performance, and decomposition products or dangerous. The humidity of the warehouse should be controlled within a moderate range to prevent moisture decomposition. It must also be stored in isolation from oxidizing agents, alkalis, etc. Due to its active chemical properties, contact with them may cause violent reactions, even the risk of explosion.
As for transportation, make sure that the packaging is intact and tightly sealed. During transportation, protect against sun exposure, rain and high temperature. When loading and unloading, pack lightly and unload lightly, avoid bumping and heavy pressure, so as to avoid package damage and material leakage. Transportation vehicles should be equipped with corresponding fire equipment and leakage emergency treatment equipment. If the package is damaged or the material leaks during transportation, it should be properly handled according to the emergency treatment method as soon as possible to prevent the spread of hazards.
In short, the storage and transportation of 4-nitrochlorobenzene-2-sulfonic acid must be handled with caution and in accordance with regulations to ensure safety and avoid accidents.
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