Linshang Chemical
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4-Nitrochlorobenzene
Linshang Chemical
|
HS Code |
867606 |
| Name | 4-Nitrochlorobenzene |
| Molecular Formula | C6H4ClNO2 |
| Molecular Weight | 157.55 |
| Appearance | Yellowish - white crystals |
| Odor | Characteristic odor |
| Melting Point | 83 - 85 °C |
| Boiling Point | 242 °C |
| Density | 1.520 g/cm³ (at 20 °C) |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in ethanol, ether, benzene |
| Vapor Pressure | 0.01 mmHg (at 25 °C) |
| Flash Point | 127 °C |
As an accredited 4-Nitrochlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 50 kg of 4 - nitrochlorobenzene packaged in sealed, corrosion - resistant drums. |
| Storage | 4 - nitrochlorobenzene should be stored in a cool, well - ventilated warehouse. Keep it away from fire and heat sources. Store it separately from oxidizing agents, reducing agents, and alkalis to prevent reactions. Ensure containers are tightly sealed to avoid leakage, and follow proper labeling and inventory management for safety. |
| Shipping | 4 - nitrochlorobenzene is shipped in tightly - sealed containers. It must be transported in accordance with regulations for hazardous chemicals, ensuring proper labeling, separation from incompatible substances, and secure handling during transit. |
Competitive 4-Nitrochlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Nitrochlorobenzene in China?
As a trusted 4-Nitrochlorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Nitrochlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4-nitrochlorobenzene?
4-Nitrochlorobenzene is also an organic compound. It has a wide range of uses and is used in various fields.
First, the pharmaceutical industry depends on it. With it as the starting material, through several chemical changes, a variety of drugs can be prepared. For example, through a series of subtle reactions, it can be converted into antibacterial and anti-inflammatory drugs, which make great contributions to healing diseases and protecting health.
Second, the manufacture of dyes is also indispensable. 4-Nitrochlorobenzene can be used as a key intermediate, which can be cleverly combined to produce colorful dyes. These dyes are used in fabric printing and dyeing to make fabrics look gorgeous and enhance their appearance, which is crucial in the textile printing and dyeing industry.
In addition, the preparation of pesticides is also used. Through chemical synthesis, it is integrated into the creation of pesticides, or it can be made into pesticides with insecticidal and weeding effects. These pesticides are of great significance in agricultural production, helping crop growth, resisting pest attacks, and ensuring crop yields.
In addition, 4-nitrochlorobenzene is also used in the fields of rubber additives and fragrances. In the manufacture of rubber additives, it may enhance the properties of rubber; in the synthesis of fragrances, it may add a unique flavor.
In summary, 4-nitrochlorobenzene has important uses in many fields such as pharmaceuticals, dyes, and pesticides, and has a profound impact on human production and life.
First, the pharmaceutical industry depends on it. With it as the starting material, through several chemical changes, a variety of drugs can be prepared. For example, through a series of subtle reactions, it can be converted into antibacterial and anti-inflammatory drugs, which make great contributions to healing diseases and protecting health.
Second, the manufacture of dyes is also indispensable. 4-Nitrochlorobenzene can be used as a key intermediate, which can be cleverly combined to produce colorful dyes. These dyes are used in fabric printing and dyeing to make fabrics look gorgeous and enhance their appearance, which is crucial in the textile printing and dyeing industry.
In addition, the preparation of pesticides is also used. Through chemical synthesis, it is integrated into the creation of pesticides, or it can be made into pesticides with insecticidal and weeding effects. These pesticides are of great significance in agricultural production, helping crop growth, resisting pest attacks, and ensuring crop yields.
In addition, 4-nitrochlorobenzene is also used in the fields of rubber additives and fragrances. In the manufacture of rubber additives, it may enhance the properties of rubber; in the synthesis of fragrances, it may add a unique flavor.
In summary, 4-nitrochlorobenzene has important uses in many fields such as pharmaceuticals, dyes, and pesticides, and has a profound impact on human production and life.
What are the physical properties of 4-nitrochlorobenzene?
4-Nitrochlorobenzene is one of the organic compounds. It has the following physical properties:
Looking at its color state, at room temperature, it is in the shape of light yellow crystals, which is easy to identify.
Smell its smell, it has a rather pungent smell, and people feel uncomfortable when they smell it.
As for the melting point, it is about 43 ° C. When heated to this temperature, it melts into a liquid state. Its boiling point is about 242 ° C. When the temperature rises, it is boiling and vaporized.
When it comes to solubility, it is extremely difficult to dissolve in water. This is because water is a polar solvent, while 4-nitrochlorobenzene has a weak polarity. According to the principle of "similar miscibility", it is difficult to dissolve. However, in organic solvents such as ethanol and ether, it is quite soluble, because the polarity of organic solvents is similar to that of 4-nitrochlorobenzene.
Its density is higher than that of water, and if placed in water, it will sink to the bottom.
In addition, 4-nitrochlorobenzene has a certain volatility. Although it is not very strong, it will slowly evaporate and disperse in the air in an open environment. These physical properties are important factors in many fields such as chemical industry and medicine, and are also relevant to its application, storage and transportation.
Looking at its color state, at room temperature, it is in the shape of light yellow crystals, which is easy to identify.
Smell its smell, it has a rather pungent smell, and people feel uncomfortable when they smell it.
As for the melting point, it is about 43 ° C. When heated to this temperature, it melts into a liquid state. Its boiling point is about 242 ° C. When the temperature rises, it is boiling and vaporized.
When it comes to solubility, it is extremely difficult to dissolve in water. This is because water is a polar solvent, while 4-nitrochlorobenzene has a weak polarity. According to the principle of "similar miscibility", it is difficult to dissolve. However, in organic solvents such as ethanol and ether, it is quite soluble, because the polarity of organic solvents is similar to that of 4-nitrochlorobenzene.
Its density is higher than that of water, and if placed in water, it will sink to the bottom.
In addition, 4-nitrochlorobenzene has a certain volatility. Although it is not very strong, it will slowly evaporate and disperse in the air in an open environment. These physical properties are important factors in many fields such as chemical industry and medicine, and are also relevant to its application, storage and transportation.
What are the chemical properties of 4-nitrochlorobenzene?
4-Nitrochlorobenzene, Chinese name 4-nitrochlorobenzene, is one of the organic compounds. Its chemical properties are unique and worthy of in-depth investigation.
In this substance, the chlorine atom coexists with the nitro group on a benzene ring. Chlorine atoms have nucleophilic substitution activity. Because the electron cloud density of the benzene ring is reduced by the electron-absorbing effect of the nitro group, the electron cloud density on the carbon connected to the chlorine atom also decreases, so that the chlorine atom is more vulnerable to nucleophilic attack. In case of hydroxyl negative ions (OH), under suitable conditions, the chlorine atom can be replaced by the hydroxyl group to form 4-nitrophenol.
Furthermore, the nitro group in 4-nitrochlorobenzene has a strong electron-absorbing conjugation effect and induction effect. This effect not only affects the electron cloud distribution of the benzene ring, but also decreases the activity of the electrophilic substitution reaction of the benzene ring, and makes the density of the nitro o-and para-position electron clouds drop more significantly. When attacking with electrophilic reagents, it tends to be meta-site. However, because the density of the meta-site electron cloud decreases less than that of the o-site and para-site, the electrophilic substitution reaction can occur, but the reaction conditions are more severe than that of benzene.
In addition, the nitro group in 4-nitrochlorobenzene can be reduced. Under suitable reducing agents and conditions, the nitro group can be gradually converted into an amino group to generate 4-chloroaniline. This reaction is quite important in organic synthesis and can be used to prepare a variety of organic compounds containing amino groups.
4-nitrochlorobenzene has a wide range of chemical properties and applications in the field of organic synthesis, but its reactivity and selectivity are deeply affected by the interaction between chlorine atoms and nitro groups in the molecular structure.
In this substance, the chlorine atom coexists with the nitro group on a benzene ring. Chlorine atoms have nucleophilic substitution activity. Because the electron cloud density of the benzene ring is reduced by the electron-absorbing effect of the nitro group, the electron cloud density on the carbon connected to the chlorine atom also decreases, so that the chlorine atom is more vulnerable to nucleophilic attack. In case of hydroxyl negative ions (OH), under suitable conditions, the chlorine atom can be replaced by the hydroxyl group to form 4-nitrophenol.
Furthermore, the nitro group in 4-nitrochlorobenzene has a strong electron-absorbing conjugation effect and induction effect. This effect not only affects the electron cloud distribution of the benzene ring, but also decreases the activity of the electrophilic substitution reaction of the benzene ring, and makes the density of the nitro o-and para-position electron clouds drop more significantly. When attacking with electrophilic reagents, it tends to be meta-site. However, because the density of the meta-site electron cloud decreases less than that of the o-site and para-site, the electrophilic substitution reaction can occur, but the reaction conditions are more severe than that of benzene.
In addition, the nitro group in 4-nitrochlorobenzene can be reduced. Under suitable reducing agents and conditions, the nitro group can be gradually converted into an amino group to generate 4-chloroaniline. This reaction is quite important in organic synthesis and can be used to prepare a variety of organic compounds containing amino groups.
4-nitrochlorobenzene has a wide range of chemical properties and applications in the field of organic synthesis, but its reactivity and selectivity are deeply affected by the interaction between chlorine atoms and nitro groups in the molecular structure.
What are 4-nitrochlorobenzene production methods?
4-Nitrochlorobenzene, as well as organic compounds, is widely used in the industrial field. There are two common methods for its preparation.
One is the nitrification method. First take chlorobenzene as a raw material and place it in a reaction kettle with mixed acid (a mixture of sulfuric acid and nitric acid). In this mixed acid, sulfuric acid can help nitric acid to produce nitroyl cations (NO < unk >), which have strong electrophilicity. The benzene ring of chlorobenzene is rich in electrons, and the nitroyl cation then attacks the benzene ring and reacts with electrophilic substitution to generate 4-nitrochlorobenzene. During the reaction, factors such as temperature and the proportion of mixed acid are crucial. If the temperature is too high, side reactions will increase and the purity of the product will decrease; if the temperature is too low, the reaction rate will be slow and Generally speaking, the reaction temperature is controlled within a certain range, and the ratio of sulfuric acid to nitric acid in the mixed acid needs to be paid close attention to to ensure the smooth progress of the reaction.
The second is the chlorination method. Nitrobenzene is used as the starting material, and chlorine gas is introduced in the presence of a specific catalyst. Nitro is used as the meta-locator group, which reduces the electron cloud density of the benzene ring, especially in the meta-position. However, under suitable conditions and the action of the catalyst, chlorine can be substituted with nitrobenzene to generate 4-nitrochlorobenzene. In this process, the choice of catalyst, the reaction time, and the rate of chlorine gas penetration all have a great influence on the reaction. An excellent catalyst can improve the selectivity and rate of the reaction, and an appropriate reaction time can ensure the yield of the product. However, improper chlorine entry rate may cause the reaction to go out of control and produce many by-products.
One is the nitrification method. First take chlorobenzene as a raw material and place it in a reaction kettle with mixed acid (a mixture of sulfuric acid and nitric acid). In this mixed acid, sulfuric acid can help nitric acid to produce nitroyl cations (NO < unk >), which have strong electrophilicity. The benzene ring of chlorobenzene is rich in electrons, and the nitroyl cation then attacks the benzene ring and reacts with electrophilic substitution to generate 4-nitrochlorobenzene. During the reaction, factors such as temperature and the proportion of mixed acid are crucial. If the temperature is too high, side reactions will increase and the purity of the product will decrease; if the temperature is too low, the reaction rate will be slow and Generally speaking, the reaction temperature is controlled within a certain range, and the ratio of sulfuric acid to nitric acid in the mixed acid needs to be paid close attention to to ensure the smooth progress of the reaction.
The second is the chlorination method. Nitrobenzene is used as the starting material, and chlorine gas is introduced in the presence of a specific catalyst. Nitro is used as the meta-locator group, which reduces the electron cloud density of the benzene ring, especially in the meta-position. However, under suitable conditions and the action of the catalyst, chlorine can be substituted with nitrobenzene to generate 4-nitrochlorobenzene. In this process, the choice of catalyst, the reaction time, and the rate of chlorine gas penetration all have a great influence on the reaction. An excellent catalyst can improve the selectivity and rate of the reaction, and an appropriate reaction time can ensure the yield of the product. However, improper chlorine entry rate may cause the reaction to go out of control and produce many by-products.
4-nitrochlorobenzene what are the precautions during use
4 - Nitrochlorobenzene is also a chemical substance. When using it, many matters should be paid attention to.
The first to bear the brunt is related to personal safety. This is a toxic substance, which can cause harm if it touches the skin, inhales its gas or takes it by mistake. Therefore, when handling, protective gear is indispensable. Protective clothing, protective gloves, and a mask or gas mask are also necessary to prevent it from harming the body.
Second, it is related to the environment. 4 - If nitrochlorobenzene enters the environment, it may cause pollution. Waste containing this substance should not be dumped at will, and it must be properly disposed of in accordance with regulations to protect the environment from its contamination.
Furthermore, it is related to operating standards. In the storage place, it should be cool, dry and well ventilated, away from fire and heat sources to prevent danger. When taking it, operate it with precision to avoid spillage. If there is a spill, clean it up immediately according to the correct method, and do not neglect it.
Again, it is related to emergency measures. The operator should be familiar with emergency methods. If you accidentally touch it, you should take off the contaminated clothes and rinse with plenty of water. If you inhale it, go to a fresh place quickly; if you take it by mistake, seek medical attention quickly. In the place, emergency equipment should also be complete to prepare for emergencies.
All of these are for the use of 4-nitrochlorobenzene should be paid attention to, and should not be ignored, in order to ensure safety and protect the environment.
The first to bear the brunt is related to personal safety. This is a toxic substance, which can cause harm if it touches the skin, inhales its gas or takes it by mistake. Therefore, when handling, protective gear is indispensable. Protective clothing, protective gloves, and a mask or gas mask are also necessary to prevent it from harming the body.
Second, it is related to the environment. 4 - If nitrochlorobenzene enters the environment, it may cause pollution. Waste containing this substance should not be dumped at will, and it must be properly disposed of in accordance with regulations to protect the environment from its contamination.
Furthermore, it is related to operating standards. In the storage place, it should be cool, dry and well ventilated, away from fire and heat sources to prevent danger. When taking it, operate it with precision to avoid spillage. If there is a spill, clean it up immediately according to the correct method, and do not neglect it.
Again, it is related to emergency measures. The operator should be familiar with emergency methods. If you accidentally touch it, you should take off the contaminated clothes and rinse with plenty of water. If you inhale it, go to a fresh place quickly; if you take it by mistake, seek medical attention quickly. In the place, emergency equipment should also be complete to prepare for emergencies.
All of these are for the use of 4-nitrochlorobenzene should be paid attention to, and should not be ignored, in order to ensure safety and protect the environment.
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