Linshang Chemical
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4-(P-Aminobenzene Sulfonamino)-5Methoxy-6-Chloro Pyrimidine)
Linshang Chemical
|
HS Code |
795136 |
| Chemical Formula | C11H11ClN4O3S |
| Molar Mass | 314.74 g/mol |
| Appearance | Typically a solid (description may vary) |
| Physical State At Room Temp | Solid |
| Solubility In Water | Low (estimated, exact value may need experimental determination) |
| Solubility In Organic Solvents | Varies depending on the solvent, e.g., more soluble in polar organic solvents like DMSO |
| Melting Point | Data may be required from experimental sources |
| Density | Experimental data needed for accurate value |
| Pka | Relevant acid - base properties data needed for pKa determination |
As an accredited 4-(P-Aminobenzene Sulfonamino)-5Methoxy-6-Chloro Pyrimidine) factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4-(p - aminobenzenesulfonamino)-5 - methoxy - 6 - chloro pyrimidine in sealed chemical - grade bags. |
| Storage | Store 4-(p -aminobenzenesulfonamino)-5 -methoxy-6 -chloropyrimidine in a cool, dry place, away from direct sunlight. Keep it in a well - sealed container to prevent moisture absorption and contact with air, which could potentially lead to degradation. Store it separately from incompatible substances, following standard chemical storage safety guidelines. |
| Shipping | Ship 4-(p - aminobenzene Sulfonamino)-5 - methoxy - 6 - chloro Pyrimidine in well - sealed, corrosion - resistant containers. Follow all hazardous chemical shipping regulations, ensuring proper labeling and secure packaging to prevent leakage during transit. |
Competitive 4-(P-Aminobenzene Sulfonamino)-5Methoxy-6-Chloro Pyrimidine) prices that fit your budget—flexible terms and customized quotes for every order.
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What is the main use of 4- (p-aminobenzene Sulfonamino) -5methoxy-6-chloro Pyrimidine?
4- (p-Aminobenzenesulfonamido) - 5-methoxy-6-chloropyrimidine is an important substance in the field of medicinal chemistry.
It is often a key intermediate in the way of pharmaceutical research and development. Due to its unique structure, it can be cleverly connected with other chemical groups through many chemical reactions to build complex compounds with specific pharmacological activities. For example, in the creation of antibacterial drugs, this basis may be derived into new antibacterial ingredients, which can interfere with their normal physiological metabolism by precisely acting on specific targets of bacteria and achieve antibacterial effect.
It also has significant functions in the process of chemical synthesis. It can be used as an important building block for organic synthesis. By virtue of its own functional group characteristics, it participates in a variety of reactions, such as nucleophilic substitution, cyclization reactions, etc., to help synthesize a series of organic compounds with novel structures, or is applied to materials science, fine chemistry and other fields, providing the possibility for the synthesis of special materials, functional additives, etc.
Or in biological activity research, as the prototype of lead compounds. Scientists take it as the starting point, modify and optimize the structure, and explore the structure-activity relationship in depth. They hope to discover new active substances with better activity, higher selectivity, and less toxic and side effects, opening a new path for the development of new drugs and contributing to the process of pharmaceutical innovation.
It is often a key intermediate in the way of pharmaceutical research and development. Due to its unique structure, it can be cleverly connected with other chemical groups through many chemical reactions to build complex compounds with specific pharmacological activities. For example, in the creation of antibacterial drugs, this basis may be derived into new antibacterial ingredients, which can interfere with their normal physiological metabolism by precisely acting on specific targets of bacteria and achieve antibacterial effect.
It also has significant functions in the process of chemical synthesis. It can be used as an important building block for organic synthesis. By virtue of its own functional group characteristics, it participates in a variety of reactions, such as nucleophilic substitution, cyclization reactions, etc., to help synthesize a series of organic compounds with novel structures, or is applied to materials science, fine chemistry and other fields, providing the possibility for the synthesis of special materials, functional additives, etc.
Or in biological activity research, as the prototype of lead compounds. Scientists take it as the starting point, modify and optimize the structure, and explore the structure-activity relationship in depth. They hope to discover new active substances with better activity, higher selectivity, and less toxic and side effects, opening a new path for the development of new drugs and contributing to the process of pharmaceutical innovation.
What are the physical properties of 4- (p-aminobenzene Sulfonamino) -5methoxy-6-chloro Pyrimidine
4- (p-Aminobenzenesulfonamido) - 5-methoxy-6-chloropyrimidine This substance has many physical properties. Looking at its morphology, it is mostly white to slightly yellow crystalline powder at room temperature, with a fine texture and a slippery feel to the touch. Its particle size is small and uniform, just like finely ground jade powder.
As for its solubility, it has a certain solubility in polar organic solvents such as ethanol and acetone. In ethanol, it is heated and stirred slightly, and then slowly melted in it to form a clear liquid, just like ice and snow melting in Chunxi. However, in water, the solubility is very small, and only some are allowed to disperse in it. It is difficult to form a homogeneous solution. It is like sand and gravel in a flood. Although it has been initialized, it is still difficult to melt.
Melting point is also one of its important physical properties. After determination, its melting point is within a specific range. At this temperature, the substance gradually transitions from solid to liquid, the lattice structure disintegrates, and the molecule is energized and flexible. This melting point characteristic can be used as a reference for identifying the purity of the substance. Pure people have precise melting points and narrow melting ranges. If they contain impurities, the melting point is offset and the melting range becomes wider, just like gold mixed with other things. The color is mixed and the melting point is different.
In addition, the density of the substance also has characteristics. Its density is moderate, placed in a specific container, and compared with other substances, it occupies a unique proportion of space and mass. This characteristic plays an important role in the distribution and mixing of different systems, affecting the ratio of materials and the uniformity of mixing. It is like a trade-off, which is fixed in everything.
Furthermore, its stability is also worthy of attention. Under normal environmental conditions, it can maintain a relatively stable state, and the chemical structure is difficult to change. However, if exposed to strong light, hot topics or special chemical atmospheres, its structure may change, and its physical properties will also change, just like a delicate flower in a storm and rain, and its appearance is easy to change.
As for its solubility, it has a certain solubility in polar organic solvents such as ethanol and acetone. In ethanol, it is heated and stirred slightly, and then slowly melted in it to form a clear liquid, just like ice and snow melting in Chunxi. However, in water, the solubility is very small, and only some are allowed to disperse in it. It is difficult to form a homogeneous solution. It is like sand and gravel in a flood. Although it has been initialized, it is still difficult to melt.
Melting point is also one of its important physical properties. After determination, its melting point is within a specific range. At this temperature, the substance gradually transitions from solid to liquid, the lattice structure disintegrates, and the molecule is energized and flexible. This melting point characteristic can be used as a reference for identifying the purity of the substance. Pure people have precise melting points and narrow melting ranges. If they contain impurities, the melting point is offset and the melting range becomes wider, just like gold mixed with other things. The color is mixed and the melting point is different.
In addition, the density of the substance also has characteristics. Its density is moderate, placed in a specific container, and compared with other substances, it occupies a unique proportion of space and mass. This characteristic plays an important role in the distribution and mixing of different systems, affecting the ratio of materials and the uniformity of mixing. It is like a trade-off, which is fixed in everything.
Furthermore, its stability is also worthy of attention. Under normal environmental conditions, it can maintain a relatively stable state, and the chemical structure is difficult to change. However, if exposed to strong light, hot topics or special chemical atmospheres, its structure may change, and its physical properties will also change, just like a delicate flower in a storm and rain, and its appearance is easy to change.
What are the chemical properties of 4- (p-aminobenzene Sulfonamino) -5methoxy-6-chloro Pyrimidine
4- (p-Aminobenzenesulfonamido) - 5-methoxy-6-chloropyrimidine, this is an organic compound. Its chemical properties are unique and of great research value.
Let's talk about its solubility first. This compound can show some solubility in organic solvents, such as ethanol and acetone. Because there are polar groups in the molecule, such as methoxy, chlorine atoms, and nitrogen and oxygen atoms in the sulfonamide group can form hydrogen bonds with organic solvents or other intermolecular forces to help them dissolve. However, it also contains non-polar parts such as benzene rings, which limit its solubility in polar solvents such as water, so the overall solubility in water is not good.
Its stability is also an important property. Under normal conditions, if the temperature and humidity are appropriate, it can remain relatively stable. When encountering strong acids and bases, the molecular structure will be affected. For example, in strong acids, the nitrogen atom of the sulfonamide group may be protonated, resulting in molecular structure changes; under strong bases, methoxy or chlorine atoms may undergo substitution reactions, resulting in structural changes.
In terms of reactivity, amino groups and chlorine atoms are active check points. Amino groups can participate in acylation, alkylation and other reactions, because there are lone pairs of electrons on the nitrogen atom, which are nucleophilic and easy to react with electrophilic reagents. As a leaving group, chlorine atoms can participate in nucleophilic substitution reactions. Many nucleophilic reagents such as sodium alcohols and amines can react with chloropyrimidine to form new compounds.
The chemical properties of this compound are complex and diverse, which not only determine its application in the field of organic synthesis, but also have a profound impact on its potential value in the pharmaceutical, pesticide and other industries. In-depth investigation of its properties will lay a solid foundation for innovation and development in related fields.
Let's talk about its solubility first. This compound can show some solubility in organic solvents, such as ethanol and acetone. Because there are polar groups in the molecule, such as methoxy, chlorine atoms, and nitrogen and oxygen atoms in the sulfonamide group can form hydrogen bonds with organic solvents or other intermolecular forces to help them dissolve. However, it also contains non-polar parts such as benzene rings, which limit its solubility in polar solvents such as water, so the overall solubility in water is not good.
Its stability is also an important property. Under normal conditions, if the temperature and humidity are appropriate, it can remain relatively stable. When encountering strong acids and bases, the molecular structure will be affected. For example, in strong acids, the nitrogen atom of the sulfonamide group may be protonated, resulting in molecular structure changes; under strong bases, methoxy or chlorine atoms may undergo substitution reactions, resulting in structural changes.
In terms of reactivity, amino groups and chlorine atoms are active check points. Amino groups can participate in acylation, alkylation and other reactions, because there are lone pairs of electrons on the nitrogen atom, which are nucleophilic and easy to react with electrophilic reagents. As a leaving group, chlorine atoms can participate in nucleophilic substitution reactions. Many nucleophilic reagents such as sodium alcohols and amines can react with chloropyrimidine to form new compounds.
The chemical properties of this compound are complex and diverse, which not only determine its application in the field of organic synthesis, but also have a profound impact on its potential value in the pharmaceutical, pesticide and other industries. In-depth investigation of its properties will lay a solid foundation for innovation and development in related fields.
What are the synthesis methods of 4- (p-aminobenzene Sulfonamino) -5methoxy-6-chloro Pyrimidine
The synthesis of 4- (p-aminobenzenesulfonamido) -5-methoxy-6-chloropyrimidine is a very important topic in the field of chemistry. To prepare this substance, various routes can be followed, as detailed below.
First, a specific compound containing a pyrimidine ring is used as the starting material. First, the starting material is suitably substituted, and the desired methoxy group and chlorine atom are introduced at the specific position of the pyrimidine ring. This process requires the selection of suitable reaction conditions and reagents, such as specific bases and solvents, to ensure the high efficiency and selectivity of the reaction.
Second, after the methoxy group and chlorine atom are successfully introduced into the pyrimidine ring, the p-aminobenzenesulfonamide group is introduced. This step can be achieved by reacting the modified pyrimidine compound with related reagents such as p-aminobenzenesulfonyl chloride. During the reaction, the reaction temperature, time and proportion of the reactants need to be strictly controlled, so that the target product with high yield and purity can be obtained.
Furthermore, during the reaction process, the products in each step need to be carefully separated and purified. Commonly used separation and purification methods include column chromatography, recrystallization, etc. Through such methods, the reaction by-products and unreacted raw materials can be effectively removed, so that the purity of the product meets the requirements of subsequent research and application.
It is also important to note that the precise regulation of reaction conditions is crucial throughout the synthesis process. Temperature, pH, reaction time and other factors all have a profound impact on the rate of reaction, yield and purity of the product. Only by accurately grasping all the conditions can 4- (p-aminobenzenesulfonamido) -5-methoxy-6-chloropyrimidine be successfully synthesized.
First, a specific compound containing a pyrimidine ring is used as the starting material. First, the starting material is suitably substituted, and the desired methoxy group and chlorine atom are introduced at the specific position of the pyrimidine ring. This process requires the selection of suitable reaction conditions and reagents, such as specific bases and solvents, to ensure the high efficiency and selectivity of the reaction.
Second, after the methoxy group and chlorine atom are successfully introduced into the pyrimidine ring, the p-aminobenzenesulfonamide group is introduced. This step can be achieved by reacting the modified pyrimidine compound with related reagents such as p-aminobenzenesulfonyl chloride. During the reaction, the reaction temperature, time and proportion of the reactants need to be strictly controlled, so that the target product with high yield and purity can be obtained.
Furthermore, during the reaction process, the products in each step need to be carefully separated and purified. Commonly used separation and purification methods include column chromatography, recrystallization, etc. Through such methods, the reaction by-products and unreacted raw materials can be effectively removed, so that the purity of the product meets the requirements of subsequent research and application.
It is also important to note that the precise regulation of reaction conditions is crucial throughout the synthesis process. Temperature, pH, reaction time and other factors all have a profound impact on the rate of reaction, yield and purity of the product. Only by accurately grasping all the conditions can 4- (p-aminobenzenesulfonamido) -5-methoxy-6-chloropyrimidine be successfully synthesized.
What is the price range of 4- (p-aminobenzene Sulfonamino) -5methoxy-6-chloro Pyrimidine in the market?
I do not know for sure that 4- (p-aminobenzenesulfonamido) -5-methoxy-6-chloropyrimidine is in the market price range. This compound may involve specialized fields such as fine chemicals and medicinal chemistry, and its price is affected by many factors.
First, purity has a great impact. High purity is difficult to prepare, the cost is high, and the price is high; low purity is easier to prepare, and the price may be low. Second, market supply and demand are of great importance. If demand is strong and supply is limited, the price will rise; conversely, if the supply is sufficient and the demand is low, the price may drop. Third, the simplicity of the preparation process also affects the price. Complex processes lead to higher costs and higher prices.
However, "Tiangong Kaiwu" describes many traditional industrial and agricultural techniques, which are rarely involved in the price of modern fine chemicals, and it is difficult to give the exact price range. To know the market price of this compound, you can consult chemical product suppliers, chemical trading platforms, or research professional market reports to obtain relatively accurate price information.
First, purity has a great impact. High purity is difficult to prepare, the cost is high, and the price is high; low purity is easier to prepare, and the price may be low. Second, market supply and demand are of great importance. If demand is strong and supply is limited, the price will rise; conversely, if the supply is sufficient and the demand is low, the price may drop. Third, the simplicity of the preparation process also affects the price. Complex processes lead to higher costs and higher prices.
However, "Tiangong Kaiwu" describes many traditional industrial and agricultural techniques, which are rarely involved in the price of modern fine chemicals, and it is difficult to give the exact price range. To know the market price of this compound, you can consult chemical product suppliers, chemical trading platforms, or research professional market reports to obtain relatively accurate price information.
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