Linshang Chemical
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4-(Tert-Butyl)-1,2-Dichlorobenzene
Linshang Chemical
|
HS Code |
628630 |
| Chemical Formula | C10H12Cl2 |
| Molar Mass | 203.11 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 240 - 242 °C |
| Melting Point | -18 °C |
| Density | 1.15 g/cm³ at 20 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents |
| Vapor Pressure | Low vapor pressure |
| Odor | Characteristic aromatic odor |
As an accredited 4-(Tert-Butyl)-1,2-Dichlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 4-(tert - butyl)-1,2 - dichlorobenzene packaged in a sealed plastic bottle. |
| Storage | 4-(tert -butyl)-1,2 -dichlorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials, to prevent leakage and exposure to air or moisture. Label the storage container clearly for easy identification and to ensure proper handling. |
| Shipping | 4-(tert -butyl)-1,2 -dichlorobenzene is shipped in specialized containers designed for hazardous chemicals. It must comply with strict regulations, ensuring proper containment to prevent spills and safeguard transport workers and the environment. |
Competitive 4-(Tert-Butyl)-1,2-Dichlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-(Tert-Butyl)-1,2-Dichlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 4- (tert - butyl) -1,2 - dichlorobenzene
4- (tert-butyl) -1,2-dichlorobenzene, which has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Due to its special structure, it can be derived from other organic compounds through various chemical reactions. For example, by substitution reaction, other functional groups can be introduced, and then organic materials with special properties and uses can be synthesized.
In the field of materials science, it also has important value. It can be used to prepare polymer materials with specific structures and properties. With its unique molecular structure, it participates in polymerization reactions, endows polymer materials with specific physical and chemical properties, such as improving the heat resistance and mechanical properties of materials, and plays a role in the preparation of high-performance engineering plastics, special fibers and other materials.
In addition, in the field of medicinal chemistry, it may assist in the synthesis of certain drugs. Its structure can be used as a basic module for the construction of drug molecules, chemically modified and modified to obtain biologically active compounds, providing a possible path for the development of new drugs. And in the fragrance industry, because of its unique chemical structure, it may be able to participate in the formulation of flavorful fragrance ingredients, adding a unique flavor to fragrance products.
In the field of materials science, it also has important value. It can be used to prepare polymer materials with specific structures and properties. With its unique molecular structure, it participates in polymerization reactions, endows polymer materials with specific physical and chemical properties, such as improving the heat resistance and mechanical properties of materials, and plays a role in the preparation of high-performance engineering plastics, special fibers and other materials.
In addition, in the field of medicinal chemistry, it may assist in the synthesis of certain drugs. Its structure can be used as a basic module for the construction of drug molecules, chemically modified and modified to obtain biologically active compounds, providing a possible path for the development of new drugs. And in the fragrance industry, because of its unique chemical structure, it may be able to participate in the formulation of flavorful fragrance ingredients, adding a unique flavor to fragrance products.
What are the physical properties of 4- (tert - butyl) -1,2 - dichlorobenzene
4- (tert-butyl) -1,2-dichlorobenzene is one of the organic compounds. Its physical properties are quite important, and I will describe them in detail today.
First of all, its appearance, at room temperature, the substance is often colorless to light yellow liquid, and the appearance is clear and slightly shiny. Its smell is specific, and ordinary people can smell it, but they can feel a pungent smell. Although this smell is not as bad as the bad smell, it is enough to attract attention.
In terms of its boiling point, it is about 230 ° C. The boiling point is the temperature limit for the substance to change from liquid to gaseous state. This boiling point indicates that 4- (tert-butyl) -1,2-dichlorobenzene needs a higher temperature to boil and gasify. As for the melting point, it is about -10 ° C or so, that is, when the temperature drops to about -10 ° C, the substance begins to condense from liquid to solid.
Furthermore, its density is about 1.15g/cm ³. The density is also the mass of the substance per unit volume. This value shows that 4 - (tert-butyl) -1,2-dichlorobenzene has a slightly higher density than water. If placed in water, it will sink to the bottom.
In terms of solubility, this compound is insoluble in water, but miscible with many organic solvents, such as ethanol, ether, acetone, etc. This property is due to the difference in its molecular structure and the forces between water molecules and organic solvent molecules.
In addition, the vapor pressure of 4- (tert-butyl) -1,2-dichlorobenzene is relatively low. The vapor pressure is also the pressure of the vapor on the surface of the liquid. The lower vapor pressure indicates that the volatilization rate is slower at room temperature, but if the temperature increases, the vapor pressure will also increase, and the volatilization will intensify.
In summary, the physical properties of 4- (tert-butyl) -1,2-dichlorobenzene, such as appearance, odor, melting boiling point, density, solubility, and vapor pressure, are all key factors in understanding this compound, and its application in chemical industry, scientific research and other fields is also of important guiding significance.
First of all, its appearance, at room temperature, the substance is often colorless to light yellow liquid, and the appearance is clear and slightly shiny. Its smell is specific, and ordinary people can smell it, but they can feel a pungent smell. Although this smell is not as bad as the bad smell, it is enough to attract attention.
In terms of its boiling point, it is about 230 ° C. The boiling point is the temperature limit for the substance to change from liquid to gaseous state. This boiling point indicates that 4- (tert-butyl) -1,2-dichlorobenzene needs a higher temperature to boil and gasify. As for the melting point, it is about -10 ° C or so, that is, when the temperature drops to about -10 ° C, the substance begins to condense from liquid to solid.
Furthermore, its density is about 1.15g/cm ³. The density is also the mass of the substance per unit volume. This value shows that 4 - (tert-butyl) -1,2-dichlorobenzene has a slightly higher density than water. If placed in water, it will sink to the bottom.
In terms of solubility, this compound is insoluble in water, but miscible with many organic solvents, such as ethanol, ether, acetone, etc. This property is due to the difference in its molecular structure and the forces between water molecules and organic solvent molecules.
In addition, the vapor pressure of 4- (tert-butyl) -1,2-dichlorobenzene is relatively low. The vapor pressure is also the pressure of the vapor on the surface of the liquid. The lower vapor pressure indicates that the volatilization rate is slower at room temperature, but if the temperature increases, the vapor pressure will also increase, and the volatilization will intensify.
In summary, the physical properties of 4- (tert-butyl) -1,2-dichlorobenzene, such as appearance, odor, melting boiling point, density, solubility, and vapor pressure, are all key factors in understanding this compound, and its application in chemical industry, scientific research and other fields is also of important guiding significance.
Is 4- (tert - butyl) -1,2 - dichlorobenzene chemically stable?
4- (tert-butyl) -1,2-dichlorobenzene is also an organic compound. In its molecular structure, above the benzene ring, the second and fourth positions are connected by a chlorine atom and a tert-butyl group, respectively. To discuss the stability of its chemical properties, its structural characteristics must be investigated.
The benzene ring has a conjugated system and has high stability. Tert-butyl is an alkyl group, which has a donor electron induction effect, which can increase the electron cloud density of the benzene ring. The chlorine atom has both an electron-absorbing induction effect and a donor electron conjugation effect, but the induction effect is stronger than the conjugation effect, which generally reduces the electron cloud density of the benzene ring.
Generally speaking, this compound is relatively stable Due to the conjugated system of benzene ring, it is not easy to occur ring-opening reaction. However, the change of electron cloud density of benzene ring will affect its electrophilic substitution reactivity. Tert-butyl increases the density of the electron cloud of the ortho-ring and the para-position. Although chlorine atoms generally reduce the density of the electron cloud of the benzene ring, to a certain extent, the density of the ortho-electron cloud also changes.
Under common conditions, 4- (tert-butyl) -1,2-dichlorobenzene can maintain its own structure. When encountering extreme conditions such as strong oxidants, strong acids, strong bases or high temperatures, its stability may be affected. Such as strong oxidizing agent or can cause the oxidation of the substituent on the benzene ring, strong acid and strong base may initiate the conversion of the substituent or the nucleophilic substitution reaction on the benzene ring.
In short, 4- (tert-butyl) -1,2-dichlorobenzene has good stability under conventional conditions, but certain extreme conditions can cause its chemical properties to change and initiate corresponding chemical reactions.
The benzene ring has a conjugated system and has high stability. Tert-butyl is an alkyl group, which has a donor electron induction effect, which can increase the electron cloud density of the benzene ring. The chlorine atom has both an electron-absorbing induction effect and a donor electron conjugation effect, but the induction effect is stronger than the conjugation effect, which generally reduces the electron cloud density of the benzene ring.
Generally speaking, this compound is relatively stable Due to the conjugated system of benzene ring, it is not easy to occur ring-opening reaction. However, the change of electron cloud density of benzene ring will affect its electrophilic substitution reactivity. Tert-butyl increases the density of the electron cloud of the ortho-ring and the para-position. Although chlorine atoms generally reduce the density of the electron cloud of the benzene ring, to a certain extent, the density of the ortho-electron cloud also changes.
Under common conditions, 4- (tert-butyl) -1,2-dichlorobenzene can maintain its own structure. When encountering extreme conditions such as strong oxidants, strong acids, strong bases or high temperatures, its stability may be affected. Such as strong oxidizing agent or can cause the oxidation of the substituent on the benzene ring, strong acid and strong base may initiate the conversion of the substituent or the nucleophilic substitution reaction on the benzene ring.
In short, 4- (tert-butyl) -1,2-dichlorobenzene has good stability under conventional conditions, but certain extreme conditions can cause its chemical properties to change and initiate corresponding chemical reactions.
What is the preparation method of 4- (tert-butyl) -1,2 -dichlorobenzene
To prepare 4- (tert-butyl) -1,2-dichlorobenzene, the method is as follows:
First take o-dichlorobenzene as the starting material, which is a readily available raw material. The structure of o-dichlorobenzene is stable, and the chlorine atom on it can be used as a check point for the reaction, laying the foundation for the subsequent introduction of tert-butyl.
Place o-dichlorobenzene in an appropriate reaction vessel and use anhydrous aluminum trichloride as a catalyst. Anhydrous aluminum trichloride is crucial in this reaction, which can activate the benzene ring of o-dichlorobenzene, making it easier to react with the tert-butyl reagent. The catalyst needs to be kept anhydrous, otherwise its activity will be affected
Then, slowly add the tert-butyl reagent, such as tert-butyl chloride. The tert-butyl cation in tert-butyl chloride can be electrophilically substituted with the benzene ring of o-dichlorobenzene under the catalysis of anhydrous aluminum trichloride. During the reaction, the reaction temperature and reaction time need to be strictly controlled. If the temperature is too low, the reaction rate is slow, and it is difficult to achieve the expected yield; if the temperature is too high, it is easy to initiate side reactions, generate unnecessary by-products, and affect the purity of the product. Generally speaking, the reaction temperature should be maintained within a certain range, such as between 0 and 50 ° C, depending on the specific reaction conditions and equipment. The reaction time also needs to be precisely controlled, usually ranging from several hours to more than ten hours. During this period, the progress of the reaction needs to be monitored with the help of instruments. For example, thin-layer chromatography (TLC) is used to track the reaction. When the raw material point is basically eliminated and the product point reaches the expected ratio, the reaction can be regarded as basically completed.
After the reaction is completed, the reaction mixture is poured into ice water to quench the reaction. Because anhydrous aluminum trichloride will react violently in water, quenching with ice water can deactivate the catalyst, and it is also conducive to the separation of the product from impurities such as the catalyst. Afterwards, the product is extracted with an organic solvent such as dichloromethane. Dichloromethane has good solubility to 4- (tert-butyl) -1,2-dichlorobenzene After extraction, the organic phase is collected and dried with anhydrous sodium sulfate to remove the water in the organic phase. Anhydrous sodium sulfate has strong water absorption, which can effectively remove the remaining trace moisture and ensure the purity of the product.
Finally, the dried organic phase is purified by distillation or column chromatography. Distillation can be separated according to the boiling point difference between the product and the impurity; column chromatography is to use the different distribution coefficients of different substances between the stationary phase and the mobile phase to achieve separation. After this purification step, pure 4- (tert-butyl) -1,2-dichlorobenzene can be obtained. In this way, the preparation of 4- (tert-butyl) -1,2-dichlorobenzene is completed.
First take o-dichlorobenzene as the starting material, which is a readily available raw material. The structure of o-dichlorobenzene is stable, and the chlorine atom on it can be used as a check point for the reaction, laying the foundation for the subsequent introduction of tert-butyl.
Place o-dichlorobenzene in an appropriate reaction vessel and use anhydrous aluminum trichloride as a catalyst. Anhydrous aluminum trichloride is crucial in this reaction, which can activate the benzene ring of o-dichlorobenzene, making it easier to react with the tert-butyl reagent. The catalyst needs to be kept anhydrous, otherwise its activity will be affected
Then, slowly add the tert-butyl reagent, such as tert-butyl chloride. The tert-butyl cation in tert-butyl chloride can be electrophilically substituted with the benzene ring of o-dichlorobenzene under the catalysis of anhydrous aluminum trichloride. During the reaction, the reaction temperature and reaction time need to be strictly controlled. If the temperature is too low, the reaction rate is slow, and it is difficult to achieve the expected yield; if the temperature is too high, it is easy to initiate side reactions, generate unnecessary by-products, and affect the purity of the product. Generally speaking, the reaction temperature should be maintained within a certain range, such as between 0 and 50 ° C, depending on the specific reaction conditions and equipment. The reaction time also needs to be precisely controlled, usually ranging from several hours to more than ten hours. During this period, the progress of the reaction needs to be monitored with the help of instruments. For example, thin-layer chromatography (TLC) is used to track the reaction. When the raw material point is basically eliminated and the product point reaches the expected ratio, the reaction can be regarded as basically completed.
After the reaction is completed, the reaction mixture is poured into ice water to quench the reaction. Because anhydrous aluminum trichloride will react violently in water, quenching with ice water can deactivate the catalyst, and it is also conducive to the separation of the product from impurities such as the catalyst. Afterwards, the product is extracted with an organic solvent such as dichloromethane. Dichloromethane has good solubility to 4- (tert-butyl) -1,2-dichlorobenzene After extraction, the organic phase is collected and dried with anhydrous sodium sulfate to remove the water in the organic phase. Anhydrous sodium sulfate has strong water absorption, which can effectively remove the remaining trace moisture and ensure the purity of the product.
Finally, the dried organic phase is purified by distillation or column chromatography. Distillation can be separated according to the boiling point difference between the product and the impurity; column chromatography is to use the different distribution coefficients of different substances between the stationary phase and the mobile phase to achieve separation. After this purification step, pure 4- (tert-butyl) -1,2-dichlorobenzene can be obtained. In this way, the preparation of 4- (tert-butyl) -1,2-dichlorobenzene is completed.
4- (tert - butyl) -1,2 - dichlorobenzene What are the precautions in storage and transportation
4 - (tert-butyl) - 1,2 - dichlorobenzene is a chemical substance. When storing and transporting, it is necessary to be careful and pay attention to many key matters.
Bear the brunt, safe storage is of paramount importance. Because of its chemical activity and latent risk, it should be stored in a cool, dry and well-ventilated place. Keep away from high temperatures, open flames and strong oxidants to prevent unexpected chemical reactions, such as combustion, explosion and other disasters. The warehouse temperature should be controlled within an appropriate range and away from heat sources. If it is placed in a very hot place, its chemical properties may change and cause stability damage.
Furthermore, the packaging must be tight and firm. Appropriate packaging materials should be used to ensure their tightness to prevent leakage. Leaks not only stain the environment, but also endanger personal safety. Packaging materials must be resistant to corrosion of the chemical to prevent package damage.
When transporting, there are also many points to pay attention to. Carriers must have professional qualifications and rich experience, familiar with the characteristics and transportation specifications of such chemicals. The means of transportation must also be clean, dry and free of other chemical residues to prevent cross-contamination. During transportation, drive at a steady speed to avoid bumps, vibrations and sudden braking to prevent leakage caused by damaged packaging.
Personnel protection should not be ignored. Those involved in storage and transportation should have personal protective equipment such as protective clothing, gloves, goggles and gas masks. After contact with this substance, be sure to wash it in time. If you accidentally leak, you should immediately deal with it according to the established emergency plan, evacuate the crowd, seal the scene, and quickly clean up, recover or harmlessly dispose of the leak by professionals.
In short, the storage and transportation of 4- (tert-butyl) -1,2-dichlorobenzene is related to safety and the environment. All links must be strictly operated in accordance with regulations, and there must be no slack in order to be foolproof.
Bear the brunt, safe storage is of paramount importance. Because of its chemical activity and latent risk, it should be stored in a cool, dry and well-ventilated place. Keep away from high temperatures, open flames and strong oxidants to prevent unexpected chemical reactions, such as combustion, explosion and other disasters. The warehouse temperature should be controlled within an appropriate range and away from heat sources. If it is placed in a very hot place, its chemical properties may change and cause stability damage.
Furthermore, the packaging must be tight and firm. Appropriate packaging materials should be used to ensure their tightness to prevent leakage. Leaks not only stain the environment, but also endanger personal safety. Packaging materials must be resistant to corrosion of the chemical to prevent package damage.
When transporting, there are also many points to pay attention to. Carriers must have professional qualifications and rich experience, familiar with the characteristics and transportation specifications of such chemicals. The means of transportation must also be clean, dry and free of other chemical residues to prevent cross-contamination. During transportation, drive at a steady speed to avoid bumps, vibrations and sudden braking to prevent leakage caused by damaged packaging.
Personnel protection should not be ignored. Those involved in storage and transportation should have personal protective equipment such as protective clothing, gloves, goggles and gas masks. After contact with this substance, be sure to wash it in time. If you accidentally leak, you should immediately deal with it according to the established emergency plan, evacuate the crowd, seal the scene, and quickly clean up, recover or harmlessly dispose of the leak by professionals.
In short, the storage and transportation of 4- (tert-butyl) -1,2-dichlorobenzene is related to safety and the environment. All links must be strictly operated in accordance with regulations, and there must be no slack in order to be foolproof.
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