Linshang Chemical
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4-Tert-Butyl-1-Chlorobenzene
Linshang Chemical
|
HS Code |
968415 |
| Chemical Formula | C10H13Cl |
| Molecular Weight | 168.66 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 213 - 214 °C |
| Density | 1.002 g/cm³ at 25 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | 84 °C |
| Odor | Aromatic odor |
As an accredited 4-Tert-Butyl-1-Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottle of 4 - tert - butyl - 1 - chlorobenzene, tightly sealed for safe storage. |
| Storage | 4 - tert - butyl - 1 - chlorobenzene should be stored in a cool, well - ventilated area away from direct sunlight. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, strong acids, and bases to prevent chemical reactions. Ensure storage areas are dry to avoid potential hydrolysis. |
| Shipping | 4 - tert - butyl - 1 - chlorobenzene is shipped in sealed, corrosion - resistant containers. Compliance with hazardous chemical shipping regulations is crucial. Adequate labeling indicates its nature for safe handling during transport. |
Competitive 4-Tert-Butyl-1-Chlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 4-Tert-Butyl-1-Chlorobenzene in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 4-Tert-Butyl-1-Chlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 4-tert-butyl-1-chlorobenzene?
The main use of 4-piperidyl-1-naphthalene sulfonate is in the field of drug synthesis. It plays a key role in the field of medicinal chemistry and is often used as a key intermediate to prepare drugs with specific biological activities.
In the preparation of some nervous system-related drugs, 4-piperidyl-1-naphthalene sulfonate can participate in complex reaction pathways due to its unique chemical structure, laying the foundation for the synthesis of compounds with precise pharmacological effects. For example, when developing drugs for the treatment of psychiatric diseases, with the help of its structural characteristics, it can effectively construct a key part of the interaction with neurotransmitter receptors, thereby regulating nerve conduction function and achieving the purpose of treating related diseases.
In the development of cardiovascular drugs, 4-piperidinyl-1-naphthalene sulfonate also plays a non-negligible role. It can construct active groups closely related to cardiovascular physiological processes through specific reactions, so as to affect key physiological functions such as cardiovascular contraction, relaxation and blood circulation, and help synthesize new drugs for the treatment of cardiovascular diseases.
In addition, in the field of anti-cancer drugs, 4-piperidinyl-1-naphthalene sulfonate also shows potential application value. By participating in complex organic synthesis steps, compounds with specific targeting effects on cancer cells can be prepared, inhibiting the growth and spread of cancer cells, and providing new possibilities for cancer treatment. With its unique chemical structure, it can subtly introduce specific active fragments into the drug molecular design, enhancing the affinity and lethality of drugs to cancer cells, while reducing damage to normal cells, thereby improving the efficacy and safety of anti-cancer drugs.
In the preparation of some nervous system-related drugs, 4-piperidyl-1-naphthalene sulfonate can participate in complex reaction pathways due to its unique chemical structure, laying the foundation for the synthesis of compounds with precise pharmacological effects. For example, when developing drugs for the treatment of psychiatric diseases, with the help of its structural characteristics, it can effectively construct a key part of the interaction with neurotransmitter receptors, thereby regulating nerve conduction function and achieving the purpose of treating related diseases.
In the development of cardiovascular drugs, 4-piperidinyl-1-naphthalene sulfonate also plays a non-negligible role. It can construct active groups closely related to cardiovascular physiological processes through specific reactions, so as to affect key physiological functions such as cardiovascular contraction, relaxation and blood circulation, and help synthesize new drugs for the treatment of cardiovascular diseases.
In addition, in the field of anti-cancer drugs, 4-piperidinyl-1-naphthalene sulfonate also shows potential application value. By participating in complex organic synthesis steps, compounds with specific targeting effects on cancer cells can be prepared, inhibiting the growth and spread of cancer cells, and providing new possibilities for cancer treatment. With its unique chemical structure, it can subtly introduce specific active fragments into the drug molecular design, enhancing the affinity and lethality of drugs to cancer cells, while reducing damage to normal cells, thereby improving the efficacy and safety of anti-cancer drugs.
What are the physical properties of 4-tert-butyl-1-chlorobenzene?
4-Hydroxyethyl-1-naphthol, also known as β-naphthol, is a kind of organic compound. It has the following physical properties:
Under normal conditions, it is white to light yellow leaf-like crystals, and in sunlight and air, the color will gradually become darker. Its smell, there is a weak phenolic odor. Regarding solubility, this substance is slightly soluble in water, but soluble in ethanol, ether, chloroform, glycerol, benzene, sodium hydroxide solutions, etc. Furthermore, the melting point of β-naphthol is between 121-123 ° C, the boiling point is 285-286 ° C, and the relative density is 1.28 (20/4 ° C). Due to its phenolic structure, β-naphthol can participate in many chemical reactions, such as forming complexes with metal ions, condensation reactions with algens, and esterification and etherification under appropriate conditions. Due to its unique physical properties and chemical activities, β-naphthol is widely used in dyes, medicine, fragrances, rubber antioxidants and many other fields. In the dye industry, it is a key intermediate for the synthesis of a variety of azo dyes; in the pharmaceutical field, it can be used as a raw material for the production of drugs; in the rubber industry, it can act as an antioxidant to enhance the antioxidant properties and service life of rubber products.
Under normal conditions, it is white to light yellow leaf-like crystals, and in sunlight and air, the color will gradually become darker. Its smell, there is a weak phenolic odor. Regarding solubility, this substance is slightly soluble in water, but soluble in ethanol, ether, chloroform, glycerol, benzene, sodium hydroxide solutions, etc. Furthermore, the melting point of β-naphthol is between 121-123 ° C, the boiling point is 285-286 ° C, and the relative density is 1.28 (20/4 ° C). Due to its phenolic structure, β-naphthol can participate in many chemical reactions, such as forming complexes with metal ions, condensation reactions with algens, and esterification and etherification under appropriate conditions. Due to its unique physical properties and chemical activities, β-naphthol is widely used in dyes, medicine, fragrances, rubber antioxidants and many other fields. In the dye industry, it is a key intermediate for the synthesis of a variety of azo dyes; in the pharmaceutical field, it can be used as a raw material for the production of drugs; in the rubber industry, it can act as an antioxidant to enhance the antioxidant properties and service life of rubber products.
Is 4-tert-butyl-1-chlorobenzene chemically stable?
4-tert-butyl-1-naphthol, its chemical properties are relatively stable. In this compound, tert-butyl is used as an electron donor group, which can enhance the electron cloud density of the naphthol system. Due to the large steric resistance of tert-butyl, it plays a certain shielding role on the activity check point of naphthol, which reduces its reactivity to a certain extent and improves its stability.
The structure of 4-tert-butyl-1-naphthol, tert-butyl is connected to naphthol. For tert-butyl, the trimethyl group also has a significant electronic effect. Due to the electron-donating properties of methyl groups, tert-butyl groups as a whole are electron-donating, which increases the electron cloud density on the naphthol ring. However, its steric resistance cannot be underestimated. During the reaction, many reagents want to interact with the activity check point of naphthol, which is often blocked by tert-butyl. For example, in the electrophilic substitution reaction, when the electrophilic reagent approaches the active position of naphthol, the space obstruction of tert-butyl increases the difficulty of the reaction and slows down the rate.
And the conjugate system of naphthol itself also contributes to its stability. The conjugate structure of the naphthol ring makes the electrons delocalized 4-tert-butyl-1-naphthol can maintain its own structure stability under common conditions, and is not prone to spontaneous decomposition or rearrangement reactions. Although its structure will change under specific conditions, such as strong oxidants, high temperatures, strong acids and bases, etc., in general environments, its chemical properties are quite stable and can be stored for a long time without significant changes.
The structure of 4-tert-butyl-1-naphthol, tert-butyl is connected to naphthol. For tert-butyl, the trimethyl group also has a significant electronic effect. Due to the electron-donating properties of methyl groups, tert-butyl groups as a whole are electron-donating, which increases the electron cloud density on the naphthol ring. However, its steric resistance cannot be underestimated. During the reaction, many reagents want to interact with the activity check point of naphthol, which is often blocked by tert-butyl. For example, in the electrophilic substitution reaction, when the electrophilic reagent approaches the active position of naphthol, the space obstruction of tert-butyl increases the difficulty of the reaction and slows down the rate.
And the conjugate system of naphthol itself also contributes to its stability. The conjugate structure of the naphthol ring makes the electrons delocalized 4-tert-butyl-1-naphthol can maintain its own structure stability under common conditions, and is not prone to spontaneous decomposition or rearrangement reactions. Although its structure will change under specific conditions, such as strong oxidants, high temperatures, strong acids and bases, etc., in general environments, its chemical properties are quite stable and can be stored for a long time without significant changes.
What are the preparation methods of 4-tert-butyl-1-chlorobenzene?
To make utensils for 4-pyridyl-1-naphthol, there are three ways.
First, take a clean pottery kettle and dry it with charcoal fire. The size of the kettle depends on the amount made. If it is a normal trial, a kettle with a diameter ruler can also be used. Prepare iron pestles and sockets to grind the medicines used. A glass funnel and a silk cloth filter screen are also required to filter out impurities. Add a few glass rods for stirring.
Second, make a set of distillation utensils. Take a copper kettle as the bottom pot, connect it with a glass retort, cover the mouth of the retort with a dome, bypass a curved pipe, and introduce a condenser. The condenser is made of tin and is about three feet long. It is hollow and wrapped in cold water, so that the steam is cooled and condensed into a liquid. This set of distillers is crucial for separating various substances and purifying the product.
Third, a balance is necessary to weigh the amount of various medicines. The balance needs to be fine and can distinguish the difference by a millimeter. There are also several measuring cups to measure the amount of liquid. There are also several porcelain bowls for temporary storage of various medicines.
All the above utensils need to be clean and unsullied before they can be used for the preparation of 4-pyridyl-1-naphthol. When preparing, use them in sequence to make the medicine mix evenly and react smoothly to obtain a pure product.
First, take a clean pottery kettle and dry it with charcoal fire. The size of the kettle depends on the amount made. If it is a normal trial, a kettle with a diameter ruler can also be used. Prepare iron pestles and sockets to grind the medicines used. A glass funnel and a silk cloth filter screen are also required to filter out impurities. Add a few glass rods for stirring.
Second, make a set of distillation utensils. Take a copper kettle as the bottom pot, connect it with a glass retort, cover the mouth of the retort with a dome, bypass a curved pipe, and introduce a condenser. The condenser is made of tin and is about three feet long. It is hollow and wrapped in cold water, so that the steam is cooled and condensed into a liquid. This set of distillers is crucial for separating various substances and purifying the product.
Third, a balance is necessary to weigh the amount of various medicines. The balance needs to be fine and can distinguish the difference by a millimeter. There are also several measuring cups to measure the amount of liquid. There are also several porcelain bowls for temporary storage of various medicines.
All the above utensils need to be clean and unsullied before they can be used for the preparation of 4-pyridyl-1-naphthol. When preparing, use them in sequence to make the medicine mix evenly and react smoothly to obtain a pure product.
What are the precautions for storing and transporting 4-tert-butyl-1-chlorobenzene?
In the storage and transportation of 4-butyl-1-naphthol, many key matters need to be paid attention to.
In terms of storage, the first choice of environment. It should be placed in a cool, dry and well-ventilated place. Because 4-butyl-1-naphthol is heated, it may cause changes in properties and even cause damage to quality. If the storage environment is humid, water vapor may react with it, affecting its chemical stability. Good ventilation can avoid the accumulation of harmful gases and reduce safety risks. Secondly, container selection is extremely critical. Containers with good sealing performance must be selected to prevent excessive contact with air and reactions such as oxidation. At the same time, the material of the container should also be suitable, and 4-butyl-1-naphthol should not be chemically reacted with to avoid contaminating the substance. Furthermore, the storage place should be kept away from fire sources, heat sources and oxidants. This substance may be flammable, and it is easy to cause fire in case of open flames and hot topics; and the oxidant comes into contact with it, or triggers a violent reaction, endangering safety.
As for transportation, first, the packaging must be tight and stable. Vibration and collision during transportation are inevitable. If the packaging is not good, 4-butyl-1-naphthol is easy to leak, which not only causes losses, but also may pollute the environment and endanger the safety of transporters. Second, the means of transportation must be clean and pollution- Other residual chemicals may react with 4-butyl-1-naphthol, causing it to deteriorate. Third, strictly follow the relevant transportation regulations. Transportation personnel should be familiar with the characteristics of 4-butyl-1-naphthol, and take protective measures during transportation, such as wearing appropriate protective equipment to prevent contact and injury. And transportation routes should be planned to avoid sensitive areas such as densely populated areas to reduce the hazards in the event of accidents.
In terms of storage, the first choice of environment. It should be placed in a cool, dry and well-ventilated place. Because 4-butyl-1-naphthol is heated, it may cause changes in properties and even cause damage to quality. If the storage environment is humid, water vapor may react with it, affecting its chemical stability. Good ventilation can avoid the accumulation of harmful gases and reduce safety risks. Secondly, container selection is extremely critical. Containers with good sealing performance must be selected to prevent excessive contact with air and reactions such as oxidation. At the same time, the material of the container should also be suitable, and 4-butyl-1-naphthol should not be chemically reacted with to avoid contaminating the substance. Furthermore, the storage place should be kept away from fire sources, heat sources and oxidants. This substance may be flammable, and it is easy to cause fire in case of open flames and hot topics; and the oxidant comes into contact with it, or triggers a violent reaction, endangering safety.
As for transportation, first, the packaging must be tight and stable. Vibration and collision during transportation are inevitable. If the packaging is not good, 4-butyl-1-naphthol is easy to leak, which not only causes losses, but also may pollute the environment and endanger the safety of transporters. Second, the means of transportation must be clean and pollution- Other residual chemicals may react with 4-butyl-1-naphthol, causing it to deteriorate. Third, strictly follow the relevant transportation regulations. Transportation personnel should be familiar with the characteristics of 4-butyl-1-naphthol, and take protective measures during transportation, such as wearing appropriate protective equipment to prevent contact and injury. And transportation routes should be planned to avoid sensitive areas such as densely populated areas to reduce the hazards in the event of accidents.
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