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5-Amino-2-Chloro-N-(2,4-Dimethylphenyl)Benzenesulphonamide
Linshang Chemical
|
HS Code |
919825 |
| Chemical Formula | C14H15ClN2O2S |
| Molecular Weight | 310.8 |
| Appearance | Solid (Typical) |
| Melting Point | Data needed |
| Boiling Point | Data needed |
| Solubility In Water | Data needed |
| Solubility In Organic Solvents | Data needed |
| Pka Value | Data needed |
| Logp Value | Data needed |
| Vapor Pressure | Data needed |
As an accredited 5-Amino-2-Chloro-N-(2,4-Dimethylphenyl)Benzenesulphonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 5 - amino - 2 - chloro - N - (2,4 - dimethylphenyl)benzenesulphonamide: Packed in 100g containers. |
| Storage | Store 5 - amino - 2 - chloro - N - (2,4 - dimethylphenyl)benzenesulphonamide in a cool, dry, well - ventilated area, away from sources of heat and ignition. Keep it in a tightly closed container, preferably in a cabinet dedicated to chemicals. Avoid storage near incompatible substances such as strong oxidizing agents or acids to prevent potential reactions and ensure its stability over time. |
| Shipping | 5 - amino - 2 - chloro - N - (2,4 - dimethylphenyl)benzenesulphonamide is shipped in sealed, corrosion - resistant containers. Compliance with hazardous chemical shipping regulations ensures safe transportation to prevent spills and environmental or health risks. |
Competitive 5-Amino-2-Chloro-N-(2,4-Dimethylphenyl)Benzenesulphonamide prices that fit your budget—flexible terms and customized quotes for every order.
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What are the chemical properties of 5-amino-2-chloro-N - (2,4-dimethylphenyl) benzenesulfonamide
The chemical properties of 5-amino-2-chloro-N- (2,4-dimethylphenyl) benzamide are quite complex, so let me explain in detail.
This compound contains amino groups, which are alkaline and can react with acids to form corresponding salts. The lone pair of electrons on its nitrogen atom can participate in various nucleophilic reactions, encountering electrophilic reagents or combining with them, triggering changes in molecular structure.
Furthermore, chlorine atoms also have unique properties in this compound. Chlorine atoms are electron-absorbing, which can reduce the electron cloud density of benzene rings, thereby affecting the electrophilic substitution reaction on benzene rings. Due to its electron-absorbing effect, the electron cloud density of the ortho-and para-position of the benzene ring decreases more than that of the meta-position, so the meta-substitution products may dominate in the electrophilic substitution reaction.
And the N - (2,4 - dimethylphenyl) part, methyl as the power supply subgroup, can increase the electron cloud density of the benzene ring, have an activation effect on the electrophilic substitution reaction, and mainly increase the electron cloud density of the ortho-and para-position significantly, making it easier for the electrophilic reagents to attack the ortho-and para-position.
In this compound, the benzamide structure and the amide bond are quite stable, but hydrolysis reaction can also occur under strong acid or strong base and heating conditions Under acidic conditions, benzoic acid and corresponding ammonium salts are hydrolyzed; under alkaline conditions, benzoate and amines are formed.
In addition, due to the characteristics of its molecular structure, the compound may have certain solubility. Due to the presence of polar groups such as amino and amide groups, it may have a certain solubility in polar solvents such as alcohols and water, but it may have a low solubility in non-polar solvents such as alkanes.
In summary, the chemical properties of 5-amino-2-chloro-N- (2,4-dimethylphenyl) benzoamide are formed by the interaction of various groups it contains, and it exhibits various chemical behaviors under different reaction conditions.
What are the physical properties of 5-amino-2-chloro-N - (2,4-dimethylphenyl) benzenesulfonamide
Fu 5-amino-2-mercapto-N - (2,4-dimethylphenyl) benzamide is an organic compound. Its physical properties are many and can be described.
Looking at its shape, it often appears solid at room temperature. Due to the strong intermolecular force, its structure is relatively stable and it is not easy to become liquid or gaseous. Its color is often white or off-white, like the first snow in winter, pure and simple, which is determined by the absorption and reflection characteristics of the molecular structure of light.
When it comes to the melting point, the melting point of this substance is quite important. The melting point is the critical temperature at which the substance changes from solid to liquid. The melting point of 5-amino-2-mercapto-N- (2,4-dimethylphenyl) benzamide can fluctuate slightly due to purity and other factors, but it is roughly within a certain range. This melting point characteristic is of critical significance in terms of separation, purification and identification.
Furthermore, solubility is also an important physical property. In organic solvents, such as ethanol, acetone, etc., it may have a certain solubility. In ethanol, polar organic solvents can also interact with the molecules of the substance through hydrogen bonds, etc., so that it is partially dissolved. However, in water, due to the influence of hydrophobic groups in the molecular structure, the solubility is poor. This difference in solubility is a key consideration in many fields such as chemical synthesis and drug preparation.
In addition, its density is also a characteristic. The density is also the mass per unit volume. The density of 5-amino-2-mercapto-N - (2,4-dimethylphenyl) benzamide is related to the accumulation mode and relative molecular weight of its molecules. Knowing its density has practical uses in chemical production, material transportation, etc.
In summary, the physical properties of 5-amino-2-mercapto-N - (2,4-dimethylphenyl) benzamide, such as morphology, color, melting point, solubility and density, etc., play an indispensable role in chemical research, industrial production and many other aspects, and can provide an important basis for practice in related fields.
Looking at its shape, it often appears solid at room temperature. Due to the strong intermolecular force, its structure is relatively stable and it is not easy to become liquid or gaseous. Its color is often white or off-white, like the first snow in winter, pure and simple, which is determined by the absorption and reflection characteristics of the molecular structure of light.
When it comes to the melting point, the melting point of this substance is quite important. The melting point is the critical temperature at which the substance changes from solid to liquid. The melting point of 5-amino-2-mercapto-N- (2,4-dimethylphenyl) benzamide can fluctuate slightly due to purity and other factors, but it is roughly within a certain range. This melting point characteristic is of critical significance in terms of separation, purification and identification.
Furthermore, solubility is also an important physical property. In organic solvents, such as ethanol, acetone, etc., it may have a certain solubility. In ethanol, polar organic solvents can also interact with the molecules of the substance through hydrogen bonds, etc., so that it is partially dissolved. However, in water, due to the influence of hydrophobic groups in the molecular structure, the solubility is poor. This difference in solubility is a key consideration in many fields such as chemical synthesis and drug preparation.
In addition, its density is also a characteristic. The density is also the mass per unit volume. The density of 5-amino-2-mercapto-N - (2,4-dimethylphenyl) benzamide is related to the accumulation mode and relative molecular weight of its molecules. Knowing its density has practical uses in chemical production, material transportation, etc.
In summary, the physical properties of 5-amino-2-mercapto-N - (2,4-dimethylphenyl) benzamide, such as morphology, color, melting point, solubility and density, etc., play an indispensable role in chemical research, industrial production and many other aspects, and can provide an important basis for practice in related fields.
What are the main uses of 5-amino-2-chloro-N - (2,4-dimethylphenyl) benzenesulfonamide?
Eh! This is one of the main uses of benzyl-2-benzyl-N- (2,4-dimethylphenyl) aniline. This compound has a specific purpose.
First, in the field of research, it may be important.
Because of benzyl amine, it often gives compounds specific biological activities. The special characteristics of this compound may enable it to synthesize compounds with antibacterial and anti-inflammatory effects. For example, some antibacterial compounds, the core of which may be introduced by groups such as benzyl, benzyl and specific phenyl groups to increase the inhibitory effect of specific pathogens and treat infectious diseases.
Second, in the field of materials, it also has its own uses. The presence of the metal base can make the surface of the gold surface biochemically react to form a self-contained film. This self-contained film can be used to repair the surface of the gold material to improve its anti-corrosion properties. For example, on the surface of some perishable gold devices, the self-contained film containing this compound can effectively block the corrosion of the metal base, and the use of the metal material can be prolonged.
Furthermore, in the synthesis of this compound, this compound is used as a component and can be used for molecular construction. Its multi-active groups, such as alkyl groups and alkyl groups, can be connected to other alkyl compounds through alkyl antibodies, such as acylation antibodies, alkyl nuclear substitution antibodies, etc., to synthesize new alkyl materials or alkyl molecules with special functions, so as to meet the needs of special alkyl compounds in multiple domains such as optical materials and catalysts.
First, in the field of research, it may be important.
Because of benzyl amine, it often gives compounds specific biological activities. The special characteristics of this compound may enable it to synthesize compounds with antibacterial and anti-inflammatory effects. For example, some antibacterial compounds, the core of which may be introduced by groups such as benzyl, benzyl and specific phenyl groups to increase the inhibitory effect of specific pathogens and treat infectious diseases.
Second, in the field of materials, it also has its own uses. The presence of the metal base can make the surface of the gold surface biochemically react to form a self-contained film. This self-contained film can be used to repair the surface of the gold material to improve its anti-corrosion properties. For example, on the surface of some perishable gold devices, the self-contained film containing this compound can effectively block the corrosion of the metal base, and the use of the metal material can be prolonged.
Furthermore, in the synthesis of this compound, this compound is used as a component and can be used for molecular construction. Its multi-active groups, such as alkyl groups and alkyl groups, can be connected to other alkyl compounds through alkyl antibodies, such as acylation antibodies, alkyl nuclear substitution antibodies, etc., to synthesize new alkyl materials or alkyl molecules with special functions, so as to meet the needs of special alkyl compounds in multiple domains such as optical materials and catalysts.
What is the synthesis method of 5-amino-2-chloro-N - (2,4-dimethylphenyl) benzenesulfonamide
To prepare 5-amino-2-bromo-N- (2,4-dimethylbenzyl) benzyl amide, the method is as follows:
First, take the appropriate starting material and use the benzyl compound as the base. The benzyl-containing reactant is placed in a suitable reaction vessel, and a specific bromination reagent is added. Under precisely controlled reaction conditions, such as suitable temperature, pressure and reaction time, the bromination reaction occurs. In this step, the reaction process needs to be carefully controlled so that the bromine atom is precisely substituted in the target position, that is, the 2-position, to obtain the bromine-containing benzyl intermediate.
Subsequently, an amination step is introduced. Select a suitable amination reagent, carefully add it to the system containing the above intermediate, and adjust the reaction environment again to make the amino group connect smoothly to the 5-position. This process requires attention to the selectivity and conversion of the reaction to avoid side reactions, so as to obtain benzyl compounds with amino groups and bromide.
Then, prepare the N - (2,4-dimethylbenzyl) moiety. React with the above modified benzyl compound with 2,4-dimethylbenzyl halide or its equivalent reagents, and promote the connection of the two through carefully selected catalysts and optimized reaction parameters to construct the N - (2,4-dimethylbenzyl) structural moiety.
Finally, the amidation reaction is carried out. Using a suitable acylating agent, under suitable basic conditions or other conditions that promote the formation of amide bonds, the obtained product is converted into the target 5-amino-2-bromo-N - (2,4-dimethylbenzyl) benzamide. After each step of the reaction, separation and purification methods such as column chromatography and recrystallization are required to ensure the purity of the product, so as to achieve the purpose of preparing high-purity target products.
First, take the appropriate starting material and use the benzyl compound as the base. The benzyl-containing reactant is placed in a suitable reaction vessel, and a specific bromination reagent is added. Under precisely controlled reaction conditions, such as suitable temperature, pressure and reaction time, the bromination reaction occurs. In this step, the reaction process needs to be carefully controlled so that the bromine atom is precisely substituted in the target position, that is, the 2-position, to obtain the bromine-containing benzyl intermediate.
Subsequently, an amination step is introduced. Select a suitable amination reagent, carefully add it to the system containing the above intermediate, and adjust the reaction environment again to make the amino group connect smoothly to the 5-position. This process requires attention to the selectivity and conversion of the reaction to avoid side reactions, so as to obtain benzyl compounds with amino groups and bromide.
Then, prepare the N - (2,4-dimethylbenzyl) moiety. React with the above modified benzyl compound with 2,4-dimethylbenzyl halide or its equivalent reagents, and promote the connection of the two through carefully selected catalysts and optimized reaction parameters to construct the N - (2,4-dimethylbenzyl) structural moiety.
Finally, the amidation reaction is carried out. Using a suitable acylating agent, under suitable basic conditions or other conditions that promote the formation of amide bonds, the obtained product is converted into the target 5-amino-2-bromo-N - (2,4-dimethylbenzyl) benzamide. After each step of the reaction, separation and purification methods such as column chromatography and recrystallization are required to ensure the purity of the product, so as to achieve the purpose of preparing high-purity target products.
5-Amino-2-chloro-N - (2,4-dimethylphenyl) benzenesulfonamide What are the precautions in storage and transportation?
5-Amino-2-bromo-N - (2,4-dimethylphenyl) benzamide should pay attention to the following things during storage and transportation:
First, moisture prevention is the key. This compound has certain hygroscopicity. If it is damp, it may cause its chemical properties to change, which affects the quality. Therefore, when storing in a dry place, it can be used to maintain a dry environment with the help of a desiccant. The packaging must also be well sealed to prevent the intrusion of external moisture.
Second, temperature control is indispensable. Excessive temperature may cause the decomposition and deterioration of the compound, and too low temperature may cause its crystalline morphology to change, affecting subsequent use. Generally speaking, it should be stored in a cool place with a temperature of 2-8 ° C. During transportation, it should also ensure that the temperature is stable. Temperature-controlled transportation equipment can be used.
Third, it is extremely important to avoid light. The substance is quite sensitive to light, and light may promote photochemical reactions, resulting in structural changes and reduced activity. When storing and transporting, opaque packaging materials should be used, such as brown bottles, black plastic bags, etc., to avoid light exposure.
Fourth, avoid contact with oxidants, acids, alkalis and other substances. This compound is chemically active. Contact with the above substances or cause violent chemical reactions, resulting in danger and even explosion. When storing and transporting, be sure to keep these substances at a safe distance.
Fifth, the packaging needs to be firm and reliable. It is inevitable to bump and vibrate during transportation. If the packaging is not strong, the compounds are easy to leak, which is not only wasted, but may also pollute the environment and endanger human health. Packaging materials should be strong enough, and the integrity of the packaging should be carefully checked before transportation.
First, moisture prevention is the key. This compound has certain hygroscopicity. If it is damp, it may cause its chemical properties to change, which affects the quality. Therefore, when storing in a dry place, it can be used to maintain a dry environment with the help of a desiccant. The packaging must also be well sealed to prevent the intrusion of external moisture.
Second, temperature control is indispensable. Excessive temperature may cause the decomposition and deterioration of the compound, and too low temperature may cause its crystalline morphology to change, affecting subsequent use. Generally speaking, it should be stored in a cool place with a temperature of 2-8 ° C. During transportation, it should also ensure that the temperature is stable. Temperature-controlled transportation equipment can be used.
Third, it is extremely important to avoid light. The substance is quite sensitive to light, and light may promote photochemical reactions, resulting in structural changes and reduced activity. When storing and transporting, opaque packaging materials should be used, such as brown bottles, black plastic bags, etc., to avoid light exposure.
Fourth, avoid contact with oxidants, acids, alkalis and other substances. This compound is chemically active. Contact with the above substances or cause violent chemical reactions, resulting in danger and even explosion. When storing and transporting, be sure to keep these substances at a safe distance.
Fifth, the packaging needs to be firm and reliable. It is inevitable to bump and vibrate during transportation. If the packaging is not strong, the compounds are easy to leak, which is not only wasted, but may also pollute the environment and endanger human health. Packaging materials should be strong enough, and the integrity of the packaging should be carefully checked before transportation.
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