Linshang Chemical
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5-Amino-3-Carboxy-1-Chlorobenzene
Linshang Chemical
|
HS Code |
573061 |
| Chemical Formula | C7H6ClNO2 |
| Molar Mass | 171.58 g/mol |
| Appearance | Solid (predicted, based on similar aromatic compounds) |
| Solubility In Water | Low solubility expected due to non - polar benzene ring and relatively small polar groups |
| Solubility In Organic Solvents | Soluble in polar organic solvents like ethanol, acetone (predicted based on structure) |
| Pka Carboxyl Group | Around 3 - 5 (estimated for aromatic carboxylic acids) |
| Pka Amino Group | Around 9 - 11 (estimated for aromatic amines) |
| Odor | No data (but may have a characteristic aromatic odor based on benzene - containing compounds) |
As an accredited 5-Amino-3-Carboxy-1-Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 5 - amino - 3 - carboxy - 1 - chlorobenzene: Packed in 1 - kg bags for secure storage and handling. |
| Storage | Store 5 - amino - 3 - carboxy - 1 - chlorobenzene in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances like strong oxidizers. It should be stored in a tightly - sealed container to prevent moisture absorption and contamination, which could affect its chemical properties. |
| Shipping | 5 - amino - 3 - carboxy - 1 - chlorobenzene is shipped in well - sealed, corrosion - resistant containers. Shipment adheres to strict chemical transport regulations, ensuring proper handling and storage to prevent spills and maintain safety during transit. |
Competitive 5-Amino-3-Carboxy-1-Chlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
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What is the chemistry of 5-amino-3-carboxy-1-chlorobenzene?
5-Amino-3-carboxyl-1-chlorobenzene, this is an organic compound. Its properties are complex and have multiple characteristics.
First talk about its physical properties. Under normal conditions, it may be a solid, due to strong intermolecular forces. Looking at its solubility, it can form hydrogen bonds with water due to its carboxyl group, and may have a certain solubility in water; however, it contains chlorine atoms and benzene rings, which are hydrophobic, resulting in limited water solubility. Its melting point is affected by intermolecular forces and hydrogen bonds. Carboxyl groups and amino groups can form hydrogen bonds, which increases the melting boiling point.
Re-discussion of chemical properties. The amino group is the power supply group, which increases the electron cloud density of the benzene ring. In the electrophilic substitution reaction of the benzene ring, the amino group is o-and para-active, which is easy to attract the attack of electrophilic reagents and cause the substitution reaction. The carboxyl group is acidic and can react with bases to form salts and water. If it interacts with sodium hydroxide, the corresponding carboxylate and water are produced. Although the chlorine atom is relatively stable on the benzene ring, it can be substituted under specific reagents and conditions. In the nucleophilic substitution reaction, if there is a strong nucleophilic reagent, the chlorine atom may be replaced.
5-amino-3-carboxyl-1-chlorphenyl has a variety of active groups and It can be used as an intermediate to produce complex organic compounds through a series of reactions, and is used in industries such as medicine, pesticides, and materials.
First talk about its physical properties. Under normal conditions, it may be a solid, due to strong intermolecular forces. Looking at its solubility, it can form hydrogen bonds with water due to its carboxyl group, and may have a certain solubility in water; however, it contains chlorine atoms and benzene rings, which are hydrophobic, resulting in limited water solubility. Its melting point is affected by intermolecular forces and hydrogen bonds. Carboxyl groups and amino groups can form hydrogen bonds, which increases the melting boiling point.
Re-discussion of chemical properties. The amino group is the power supply group, which increases the electron cloud density of the benzene ring. In the electrophilic substitution reaction of the benzene ring, the amino group is o-and para-active, which is easy to attract the attack of electrophilic reagents and cause the substitution reaction. The carboxyl group is acidic and can react with bases to form salts and water. If it interacts with sodium hydroxide, the corresponding carboxylate and water are produced. Although the chlorine atom is relatively stable on the benzene ring, it can be substituted under specific reagents and conditions. In the nucleophilic substitution reaction, if there is a strong nucleophilic reagent, the chlorine atom may be replaced.
5-amino-3-carboxyl-1-chlorphenyl has a variety of active groups and It can be used as an intermediate to produce complex organic compounds through a series of reactions, and is used in industries such as medicine, pesticides, and materials.
What are the main uses of 5-amino-3-carboxy-1-chlorobenzene?
5-Amino-3-carboxyl-1-chlorobenzene, which is widely used in the field of chemical medicine.
In the process of pharmaceutical research and development, it can be a key intermediate. Due to the characteristics of amino groups, carboxyl groups and chlorine atoms, they can undergo various chemical reactions and blend with other compounds to create complex drug molecules. For example, amino groups can condensate with carboxylic acid compounds to form amide bonds, which are important structural fragments of many drug molecules and have a profound impact on drug activity and efficacy. For example, carboxyl groups can participate in esterification reactions or form salts with alkali metal ions, which is of great benefit to improving the solubility and stability of drugs. After the chlorine atom is introduced into the molecule, it can adjust the lipid solubility of the drug, enhance its interaction with biological targets, and then improve the efficacy.
In the field of materials science, it also has its uses. With its unique chemical structure, it can participate in the synthesis of polymer materials. If it reacts with monomers with active functional groups, it can build new polymers. Its amino and carboxyl groups can be used as cross-linking points to form a three-dimensional network structure of the polymer, enhancing the mechanical properties and thermal stability of the material. At the same time, due to the presence of chlorine atoms, or endowing materials with special flame retardant properties, it has great potential in the preparation of fireproof materials.
Furthermore, in the field of organic synthetic chemistry, it is an important synthetic block. Chemists can use their functional groups to carry out various classical organic reactions, such as nucleophilic substitution, electrophilic substitution, etc., to build a complex organic molecular skeleton, providing a foundation for the synthesis of novel organic compounds, expanding the boundaries of organic synthesis, and assisting the continuous development of organic chemistry.
In the process of pharmaceutical research and development, it can be a key intermediate. Due to the characteristics of amino groups, carboxyl groups and chlorine atoms, they can undergo various chemical reactions and blend with other compounds to create complex drug molecules. For example, amino groups can condensate with carboxylic acid compounds to form amide bonds, which are important structural fragments of many drug molecules and have a profound impact on drug activity and efficacy. For example, carboxyl groups can participate in esterification reactions or form salts with alkali metal ions, which is of great benefit to improving the solubility and stability of drugs. After the chlorine atom is introduced into the molecule, it can adjust the lipid solubility of the drug, enhance its interaction with biological targets, and then improve the efficacy.
In the field of materials science, it also has its uses. With its unique chemical structure, it can participate in the synthesis of polymer materials. If it reacts with monomers with active functional groups, it can build new polymers. Its amino and carboxyl groups can be used as cross-linking points to form a three-dimensional network structure of the polymer, enhancing the mechanical properties and thermal stability of the material. At the same time, due to the presence of chlorine atoms, or endowing materials with special flame retardant properties, it has great potential in the preparation of fireproof materials.
Furthermore, in the field of organic synthetic chemistry, it is an important synthetic block. Chemists can use their functional groups to carry out various classical organic reactions, such as nucleophilic substitution, electrophilic substitution, etc., to build a complex organic molecular skeleton, providing a foundation for the synthesis of novel organic compounds, expanding the boundaries of organic synthesis, and assisting the continuous development of organic chemistry.
What are 5-amino-3-carboxy-1-chlorobenzene synthesis methods?
For 5-amino-3-carboxyl-1-chlorobenzene, there are several ways to synthesize it. First, it can be started with the corresponding nitro compound. First, take a benzene derivative containing nitro, carboxyl and chlorine atoms, and use an appropriate reducing agent, such as iron and hydrochloric acid, or hydrogen in the presence of a catalyst such as palladium carbon, to reduce the nitro group to an amino group to obtain the target product. In this process, attention should be paid to the control of reaction conditions, such as temperature, pressure and catalyst dosage, which are related to the rate and yield of the reaction.
Second, or from halogenated benzoic acid. First, introduce an amino group into the benzene ring by a suitable method. For example, by diazotization, the amino group is introduced into a specific position. First, halobenzoic acid is treated with a diazotization reagent to form a diazo salt, and then the diazo group is converted into an amino group with a reducing agent. However, the conditions of the diazotization reaction should be carefully controlled during the operation. The temperature should be controlled at a low temperature to prevent the decomposition of the diazo salt and affect the yield.
Furthermore, benzene can also be used as the starting material. First, through a series of reactions, carboxyl groups, chlorine atoms and amino groups are introduced in sequence. For example, carboxyl groups are first introduced by a Fu-gram reaction, then chlorine atoms are introduced under suitable conditions, and finally amino groups are introduced through an appropriate amination reaction. However, this approach has many steps, and each step needs to be carefully planned. Purification of each step is also crucial to ensure the purity of the final product. In conclusion, the synthesis of 5-amino-3-carboxyl-1-chlorobenzene requires considering the availability of raw materials, the difficulty of reaction and the cost, and choosing an appropriate method.
Second, or from halogenated benzoic acid. First, introduce an amino group into the benzene ring by a suitable method. For example, by diazotization, the amino group is introduced into a specific position. First, halobenzoic acid is treated with a diazotization reagent to form a diazo salt, and then the diazo group is converted into an amino group with a reducing agent. However, the conditions of the diazotization reaction should be carefully controlled during the operation. The temperature should be controlled at a low temperature to prevent the decomposition of the diazo salt and affect the yield.
Furthermore, benzene can also be used as the starting material. First, through a series of reactions, carboxyl groups, chlorine atoms and amino groups are introduced in sequence. For example, carboxyl groups are first introduced by a Fu-gram reaction, then chlorine atoms are introduced under suitable conditions, and finally amino groups are introduced through an appropriate amination reaction. However, this approach has many steps, and each step needs to be carefully planned. Purification of each step is also crucial to ensure the purity of the final product. In conclusion, the synthesis of 5-amino-3-carboxyl-1-chlorobenzene requires considering the availability of raw materials, the difficulty of reaction and the cost, and choosing an appropriate method.
5-amino-3-carboxy-1-chlorobenzene What are the precautions during storage and transportation?
5-Amino-3-carboxyl-1-chlorobenzene is also an organic compound. When storing and transporting, pay attention to many matters to ensure its quality and safety.
First words storage, this compound should be placed in a cool, dry and well ventilated place. If it is covered in high temperature and humid environment, it is easy to cause deterioration. High temperature can cause molecular movement to intensify, or cause chemical reactions; humidity may cause substances to absorb moisture, affecting its purity and stability. And should be kept away from fire and heat sources, because it has certain chemical activity, in case of open flame, hot topic or risk of combustion and explosion.
Furthermore, when storing, it should be stored separately from oxidants, acids, bases, etc., and must not be mixed. Such substances are prone to chemical reactions with 5-amino-3-carboxyl-1-chlorobenzene, such as redox, acid-base neutralization, etc., resulting in changes in their chemical structure and loss of their original properties.
As for transportation, caution must also be taken. It should be ensured that the packaging is complete and the loading is secure. During transportation, the speed of the vehicle should not be too fast to prevent the package from being damaged due to bumps and collisions, and the items should leak. At the same time, the transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment for emergencies. If a leak occurs during transportation, emergency measures should be taken immediately to evacuate the crowd and prevent the spread of pollution.
In short, the storage and transportation of 5-amino-3-carboxyl-1-chlorobenzene should be strictly adhered to and handled with caution to ensure the safety of personnel and the integrity of materials.
First words storage, this compound should be placed in a cool, dry and well ventilated place. If it is covered in high temperature and humid environment, it is easy to cause deterioration. High temperature can cause molecular movement to intensify, or cause chemical reactions; humidity may cause substances to absorb moisture, affecting its purity and stability. And should be kept away from fire and heat sources, because it has certain chemical activity, in case of open flame, hot topic or risk of combustion and explosion.
Furthermore, when storing, it should be stored separately from oxidants, acids, bases, etc., and must not be mixed. Such substances are prone to chemical reactions with 5-amino-3-carboxyl-1-chlorobenzene, such as redox, acid-base neutralization, etc., resulting in changes in their chemical structure and loss of their original properties.
As for transportation, caution must also be taken. It should be ensured that the packaging is complete and the loading is secure. During transportation, the speed of the vehicle should not be too fast to prevent the package from being damaged due to bumps and collisions, and the items should leak. At the same time, the transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment for emergencies. If a leak occurs during transportation, emergency measures should be taken immediately to evacuate the crowd and prevent the spread of pollution.
In short, the storage and transportation of 5-amino-3-carboxyl-1-chlorobenzene should be strictly adhered to and handled with caution to ensure the safety of personnel and the integrity of materials.
5-amino-3-carboxy-1-chlorobenzene impact on the environment and people
5-Amino-3-carboxyl-1-chlorobenzene, this is an organic compound. The impact on the environment and human body should be carefully investigated.
First of all, its impact on the environment. If this substance enters the natural environment, its chemical properties may cause ecological disturbance. In water bodies, it may affect aquatic organisms. Because of its specific chemical structure, or difficult to degrade, it accumulates in the sediment at the bottom of the water, gradually affecting the balance of the aquatic ecosystem. Aquatic plants or due to abnormal uptake, causing physiological processes such as photosynthesis to be disturbed; aquatic animals or due to exposure to or ingestion of this substance, physiological functions are damaged, reproduction and growth may be unfavorable. In the soil environment, it may interact with soil particles, change soil chemical properties, and affect soil microbial communities. Soil microorganisms are the key to soil ecology, and their activity and community structure change, or cause soil fertility to decrease, affecting plant growth.
Times and its impact on the human body. Inhalation through the respiratory tract, skin contact or oral ingestion can cause harm to the human body. Entering the body from the respiratory tract, or irritating the respiratory mucosa, causing cough, asthma and other diseases. After entering the blood circulation, it may reach various organs and tissues, damaging their normal functions. If it comes into contact with the skin, or irritates the skin, it can cause redness, swelling, itching, and even allergic reactions. Oral ingestion, in the digestive system or irritating the gastrointestinal mucosa, causing nausea, vomiting, abdominal pain and other symptoms. Long-term exposure, this substance may accumulate in the body and damage important organs such as liver and kidney. Because it contains chlorine and amino, carboxyl and other groups, or interferes with the normal biochemical reactions of the human body, affects cell metabolism, and even has a potential carcinogenic risk.
In summary, 5-amino-3-carboxyl-1-chlorobenzene is potentially harmful to the environment and human body. When treated with caution, its production, use and discharge should be strictly controlled to reduce its threat to ecology and human health.
First of all, its impact on the environment. If this substance enters the natural environment, its chemical properties may cause ecological disturbance. In water bodies, it may affect aquatic organisms. Because of its specific chemical structure, or difficult to degrade, it accumulates in the sediment at the bottom of the water, gradually affecting the balance of the aquatic ecosystem. Aquatic plants or due to abnormal uptake, causing physiological processes such as photosynthesis to be disturbed; aquatic animals or due to exposure to or ingestion of this substance, physiological functions are damaged, reproduction and growth may be unfavorable. In the soil environment, it may interact with soil particles, change soil chemical properties, and affect soil microbial communities. Soil microorganisms are the key to soil ecology, and their activity and community structure change, or cause soil fertility to decrease, affecting plant growth.
Times and its impact on the human body. Inhalation through the respiratory tract, skin contact or oral ingestion can cause harm to the human body. Entering the body from the respiratory tract, or irritating the respiratory mucosa, causing cough, asthma and other diseases. After entering the blood circulation, it may reach various organs and tissues, damaging their normal functions. If it comes into contact with the skin, or irritates the skin, it can cause redness, swelling, itching, and even allergic reactions. Oral ingestion, in the digestive system or irritating the gastrointestinal mucosa, causing nausea, vomiting, abdominal pain and other symptoms. Long-term exposure, this substance may accumulate in the body and damage important organs such as liver and kidney. Because it contains chlorine and amino, carboxyl and other groups, or interferes with the normal biochemical reactions of the human body, affects cell metabolism, and even has a potential carcinogenic risk.
In summary, 5-amino-3-carboxyl-1-chlorobenzene is potentially harmful to the environment and human body. When treated with caution, its production, use and discharge should be strictly controlled to reduce its threat to ecology and human health.
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