Linshang Chemical
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5-Bromo-2,4-Dichlorofluorobenzene
Linshang Chemical
|
HS Code |
152914 |
| Chemical Formula | C6H2BrCl2F |
| Appearance | Typically a colorless to light - colored liquid |
| Boiling Point | Around 200 - 220 °C (approximate, may vary with pressure) |
| Solubility In Water | Poorly soluble as it is an organic halide |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Vapor Pressure | Low vapor pressure at room temperature |
As an accredited 5-Bromo-2,4-Dichlorofluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottle of 5 - bromo - 2,4 - dichlorofluorobenzene, securely packaged. |
| Storage | 5 - bromo - 2,4 - dichlorofluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent leakage and exposure to air or moisture. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential chemical reactions. |
| Shipping | 5 - bromo - 2,4 - dichlorofluorobenzene is a chemical. Shipping should comply with relevant hazardous material regulations. It must be properly packaged to prevent leakage, and transported by carriers authorized for such chemicals. |
Competitive 5-Bromo-2,4-Dichlorofluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 5-Bromo-2,4-Dichlorofluorobenzene in China?
As a trusted 5-Bromo-2,4-Dichlorofluorobenzene manufacturer, we deliver:
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 5-Bromo-2,4-Dichlorofluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 5-bromo-2,4-dichlorobenzene?
5-Bromo-2,4-difluoroanisole is a crucial intermediate in the field of organic synthesis. It has a wide range of main uses and can be used to prepare many specific drugs in pharmaceutical synthesis. Organic compounds containing fluorine and bromine often have unique biological activities and pharmacological properties, which can provide a key structural basis for drug development and improve drug efficacy, stability and selectivity. For example, it can synthesize a variety of drugs such as antibacterial, antiviral, and anti-tumor to deal with various diseases.
In the field of pesticide synthesis, this compound is also very useful. With its special structure, it can prepare highly efficient, low-toxic, and environmentally friendly pesticides. The fluorine-containing and bromine structures endow pesticides with excellent insecticidal, bactericidal and herbicidal activities, which can effectively control crop diseases and pests, improve crop yield and quality, and have little impact on the environment, which is in line with the current needs of green agriculture development.
In addition, in the field of materials science, 5-bromo-2,4-difluoroanisole can be used as a raw material for the synthesis of special polymer materials. After specific chemical reactions, the introduction of fluorine and bromine atoms into high molecular structures can improve material properties, such as improving material heat resistance, corrosion resistance, electrical properties, etc., so it is widely used in high-end fields such as electronics and aerospace.
Furthermore, in the study of organic synthetic chemistry, it is an important intermediate, providing convenience for the construction of complex organic molecular structures. Chemists can prepare organic compounds with diverse structures by performing functional group transformation, coupling reactions, etc., expanding the scope and depth of organic synthetic chemistry research, and promoting the continuous development of organic chemistry.
In the field of pesticide synthesis, this compound is also very useful. With its special structure, it can prepare highly efficient, low-toxic, and environmentally friendly pesticides. The fluorine-containing and bromine structures endow pesticides with excellent insecticidal, bactericidal and herbicidal activities, which can effectively control crop diseases and pests, improve crop yield and quality, and have little impact on the environment, which is in line with the current needs of green agriculture development.
In addition, in the field of materials science, 5-bromo-2,4-difluoroanisole can be used as a raw material for the synthesis of special polymer materials. After specific chemical reactions, the introduction of fluorine and bromine atoms into high molecular structures can improve material properties, such as improving material heat resistance, corrosion resistance, electrical properties, etc., so it is widely used in high-end fields such as electronics and aerospace.
Furthermore, in the study of organic synthetic chemistry, it is an important intermediate, providing convenience for the construction of complex organic molecular structures. Chemists can prepare organic compounds with diverse structures by performing functional group transformation, coupling reactions, etc., expanding the scope and depth of organic synthetic chemistry research, and promoting the continuous development of organic chemistry.
What are the physical properties of 5-bromo-2,4-dichlorobenzene?
5-% bromo-2,4-difluoroanisole is an organic compound with specific physical properties. It is often liquid at room temperature, and it is colorless and transparent when viewed, with a slight odor.
The boiling point of this substance is within a certain range, according to experimental determination, about several degrees Celsius (the specific value varies depending on the experimental conditions). Boiling point, as a physical property, is very critical for the separation and purification of compounds. In distillation and other operations, by virtue of its boiling point difference, 5-% bromo-2,4-difluoroanisole can be effectively separated from the mixture.
Its melting point is also an important physical property, and there is a fixed melting point value under specific conditions. Melting point information helps to determine the purity of the compound. If it contains impurities, the melting point is usually reduced and the melting range is widened.
The density of 5-% bromo-2,4-difluoroanisole is different from that of water. In chemical production, the density difference is used to separate it from other substances by layering and other means.
In terms of solubility, it shows certain solubility in organic solvents such as ethanol and ether, but poor solubility in water. This characteristic determines its application in the selection of chemical reaction media and product separation. For example, some organic reactions use ethanol as a solvent, and 5-% bromo-2,4-difluoroanisole can be well dissolved in it, which is conducive to uniform and efficient reaction.
In addition, the compound has a certain volatility. Although the volatility is not strong, it still needs to be paid attention to when storing and using. Operate in a well-ventilated environment to prevent its evaporation and accumulation from causing safety hazards.
The boiling point of this substance is within a certain range, according to experimental determination, about several degrees Celsius (the specific value varies depending on the experimental conditions). Boiling point, as a physical property, is very critical for the separation and purification of compounds. In distillation and other operations, by virtue of its boiling point difference, 5-% bromo-2,4-difluoroanisole can be effectively separated from the mixture.
Its melting point is also an important physical property, and there is a fixed melting point value under specific conditions. Melting point information helps to determine the purity of the compound. If it contains impurities, the melting point is usually reduced and the melting range is widened.
The density of 5-% bromo-2,4-difluoroanisole is different from that of water. In chemical production, the density difference is used to separate it from other substances by layering and other means.
In terms of solubility, it shows certain solubility in organic solvents such as ethanol and ether, but poor solubility in water. This characteristic determines its application in the selection of chemical reaction media and product separation. For example, some organic reactions use ethanol as a solvent, and 5-% bromo-2,4-difluoroanisole can be well dissolved in it, which is conducive to uniform and efficient reaction.
In addition, the compound has a certain volatility. Although the volatility is not strong, it still needs to be paid attention to when storing and using. Operate in a well-ventilated environment to prevent its evaporation and accumulation from causing safety hazards.
What are the synthesis methods of 5-bromo-2,4-dichlorofluorobenzene?
The synthesis of 5-bromo-2,4-difluoroanisole has various paths. First, the halogenated aromatics are used as the beginning, and the method of nucleophilic substitution is borrowed. First, the aromatic hydrocarbons with active halogen atoms are encountered with nucleophilic reagents containing methoxy groups, such as halogenated benzene and sodium methoxide in a temperature-appropriate agent. The halogen atom is methoxy, and then the desired 5-bromo-2,4-difluoroanisole is prepared by bromination and fluorination. This way, methoxy is easier to introduce, but the halogenation step needs to be controlled to achieve selectivity and yield.
Second, from phenols. Phenols and haloalkanes are deposited in bases to form ether bonds. For example, phenyl series containing phenols, halomethane in potassium carbonate and other basic agents should be used in an appropriate solvent to obtain anisole ethers. Subsequent bromination and fluorination can also prepare the target. This diameter ether formation step is relatively simple, but the phenolic activity is different, or conditions need to be adjusted to promote the reaction.
Third, borate esters are used as the base. The coupling reaction of aromatic borate esters and halides catalyzed by palladium can lead groups. First, borate is coupled with halomethane to obtain methoxyphenylborate, and then reacts with brominating agent and fluorinating agent in sequence. After catalysis and substitution, 5-bromo-2,4-difluoroanisole is obtained. In this way, carbon-heteroaryl bonds can be precisely established by catalytic coupling, but the selection and optimization of the catalytic system is crucial, and it is related to the reaction efficiency and product purity.
Each method has its advantages and disadvantages. In actual synthesis, depending on the availability of raw materials, cost, yield and purity, the method is selected to achieve the best synthesis effect.
Second, from phenols. Phenols and haloalkanes are deposited in bases to form ether bonds. For example, phenyl series containing phenols, halomethane in potassium carbonate and other basic agents should be used in an appropriate solvent to obtain anisole ethers. Subsequent bromination and fluorination can also prepare the target. This diameter ether formation step is relatively simple, but the phenolic activity is different, or conditions need to be adjusted to promote the reaction.
Third, borate esters are used as the base. The coupling reaction of aromatic borate esters and halides catalyzed by palladium can lead groups. First, borate is coupled with halomethane to obtain methoxyphenylborate, and then reacts with brominating agent and fluorinating agent in sequence. After catalysis and substitution, 5-bromo-2,4-difluoroanisole is obtained. In this way, carbon-heteroaryl bonds can be precisely established by catalytic coupling, but the selection and optimization of the catalytic system is crucial, and it is related to the reaction efficiency and product purity.
Each method has its advantages and disadvantages. In actual synthesis, depending on the availability of raw materials, cost, yield and purity, the method is selected to achieve the best synthesis effect.
What are the precautions for storing and transporting 5-bromo-2,4-dichlorofluorobenzene?
When storing and transporting 5-% cyanogen-2,4-difluorobenzoic acid, the following general matters should be paid attention to:
First, because of its toxicity, it is related to personnel safety. Be sure to equip contacts with appropriate protective equipment, such as gas masks, protective gloves and protective clothing, to prevent skin contact, inhalation or accidental ingestion, causing physical damage. In the operating place, complete ventilation facilities are also required to allow the air to flow smoothly and disperse harmful gases that may escape in time.
Second, temperature and humidity have a great impact. This substance is more sensitive to temperature and humidity, and should be stored in a cool, dry place to avoid high temperature and humid environment. High temperature can easily cause its chemical properties to change, and humidity may cause deliquescence, which affects the quality. Therefore, it is recommended to install a temperature and humidity control device in the warehouse to strictly control the environmental conditions.
Third, the packaging must be tight. When transporting and storing, use high-quality packaging materials to ensure that the packaging is not damaged or leaked. It is often packed in sealed containers to prevent contact with air, moisture, etc. Warning signs and related information should also be clearly marked on the outside of the package, such as "toxic" and "corrosive", so that the contact person can see at a glance.
Fourth, isolated storage is extremely critical. Do not mix with oxidants, reducing agents, acids, alkalis, etc., because it may react violently with these substances, causing danger. It should be stored in zones and classified, and there should be obvious intervals and labels between different types of chemicals.
Fifth, follow the transportation regulations. When transshipment, it is strictly implemented in accordance with relevant regulations and standards, and the means and methods of transportation are selected in compliance. Transportation personnel need to be professionally trained, familiar with emergency treatment methods, and closely monitored during transportation to ensure the safety of the goods.
First, because of its toxicity, it is related to personnel safety. Be sure to equip contacts with appropriate protective equipment, such as gas masks, protective gloves and protective clothing, to prevent skin contact, inhalation or accidental ingestion, causing physical damage. In the operating place, complete ventilation facilities are also required to allow the air to flow smoothly and disperse harmful gases that may escape in time.
Second, temperature and humidity have a great impact. This substance is more sensitive to temperature and humidity, and should be stored in a cool, dry place to avoid high temperature and humid environment. High temperature can easily cause its chemical properties to change, and humidity may cause deliquescence, which affects the quality. Therefore, it is recommended to install a temperature and humidity control device in the warehouse to strictly control the environmental conditions.
Third, the packaging must be tight. When transporting and storing, use high-quality packaging materials to ensure that the packaging is not damaged or leaked. It is often packed in sealed containers to prevent contact with air, moisture, etc. Warning signs and related information should also be clearly marked on the outside of the package, such as "toxic" and "corrosive", so that the contact person can see at a glance.
Fourth, isolated storage is extremely critical. Do not mix with oxidants, reducing agents, acids, alkalis, etc., because it may react violently with these substances, causing danger. It should be stored in zones and classified, and there should be obvious intervals and labels between different types of chemicals.
Fifth, follow the transportation regulations. When transshipment, it is strictly implemented in accordance with relevant regulations and standards, and the means and methods of transportation are selected in compliance. Transportation personnel need to be professionally trained, familiar with emergency treatment methods, and closely monitored during transportation to ensure the safety of the goods.
What are the effects of 5-bromo-2,4-dichlorofluorobenzene on the environment and human health?
5-% hydrazine-2,4-dinitrobenzene has many effects on the environment and human health. This substance has a certain stability in the environment and is not easy to degrade quickly. It can diffuse through various channels, such as flowing into water bodies with wastewater, remaining in the soil, causing pollution to aquatic ecosystems and soil environments.
Toxic to the human body. If exposed to humans, it can be absorbed through the skin, inhaled by the respiratory tract or ingested into the body. Damage the nervous system, causing symptoms such as dizziness, fatigue, and insomnia; affect the hematopoietic system, causing blood diseases such as anemia and leukopenia; and irritate the respiratory tract and skin, causing respiratory inflammation and skin allergies. Long-term exposure may even increase the risk of cancer. Therefore, in the production and use of products containing 5% hydrazine-2,4-dinitrobenzene, it is necessary to strictly follow safety operating procedures, take protective measures, and properly dispose of waste to reduce the harm to the environment and human health.
Toxic to the human body. If exposed to humans, it can be absorbed through the skin, inhaled by the respiratory tract or ingested into the body. Damage the nervous system, causing symptoms such as dizziness, fatigue, and insomnia; affect the hematopoietic system, causing blood diseases such as anemia and leukopenia; and irritate the respiratory tract and skin, causing respiratory inflammation and skin allergies. Long-term exposure may even increase the risk of cancer. Therefore, in the production and use of products containing 5% hydrazine-2,4-dinitrobenzene, it is necessary to strictly follow safety operating procedures, take protective measures, and properly dispose of waste to reduce the harm to the environment and human health.
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