Linshang Chemical
PRODUCTS
5-Bromo-2-Chloro-1,3-Difluorobenzene
Linshang Chemical
|
HS Code |
833808 |
| Chemical Formula | C6H2BrClF2 |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 193 - 194 °C |
| Density | 1.815 g/cm³ |
| Solubility | Insoluble in water, soluble in organic solvents like ethanol, ether |
| Flash Point | 78 °C |
| Stability | Stable under normal conditions, avoid strong oxidizing agents |
As an accredited 5-Bromo-2-Chloro-1,3-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 5 - bromo - 2 - chloro - 1,3 - difluorobenzene packaged in a sealed glass bottle. |
| Storage | 5 - Bromo - 2 - chloro - 1,3 - difluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, acids, and bases to prevent potential chemical reactions. |
| Shipping | 5 - bromo - 2 - chloro - 1,3 - difluorobenzene is shipped in properly labeled, corrosion - resistant containers. Shipment follows strict chemical transport regulations to ensure safety during transit, avoiding exposure to heat and incompatible substances. |
Competitive 5-Bromo-2-Chloro-1,3-Difluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 5-Bromo-2-Chloro-1,3-Difluorobenzene in China?
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Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 5-Bromo-2-Chloro-1,3-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 5-bromo-2-chloro-1,3-difluorobenzene?
5-Bromo-2-chloro-1,3-difluorobenzene is a class of organic compounds. It has a wide range of uses and is significant in various fields.
The first is in the field of medicinal chemistry. This compound is often a key intermediate in the synthesis of drugs. Due to its special chemical structure, it can combine with other molecules through specific chemical reactions to build complex molecular structures with specific pharmacological activities. For example, when developing antibacterial drugs, it may be used as a starting material to generate drugs with inhibitory or killing effects on specific pathogens through multi-step reactions.
Furthermore, it is also indispensable in the field of materials science. In the preparation of high-performance organic materials, 5-bromo-2-chloro-1,3-difluorobenzene can participate in the synthesis process of materials. By ingeniously designing the reaction path, it can be introduced into the polymer to improve the properties of the material, such as enhancing the heat resistance, chemical resistance, or even endowing the material with special optical or electrical properties, laying the foundation for the preparation of new electronic devices, optical materials, etc.
In addition, in the field of pesticide chemistry, it also plays an important role. Based on it, many highly efficient and low-toxic pesticides can be synthesized. Such pesticides may be highly selective to specific pests, capable of precisely killing pests, while minimizing the impact on the environment, and contributing to the sustainable development of agriculture. In conclusion, 5-bromo-2-chloro-1,3-difluorobenzene plays an important role in many fields such as medicine, materials, and pesticides due to its unique chemical properties, providing a key chemical basis for technological innovation and development in various fields.
The first is in the field of medicinal chemistry. This compound is often a key intermediate in the synthesis of drugs. Due to its special chemical structure, it can combine with other molecules through specific chemical reactions to build complex molecular structures with specific pharmacological activities. For example, when developing antibacterial drugs, it may be used as a starting material to generate drugs with inhibitory or killing effects on specific pathogens through multi-step reactions.
Furthermore, it is also indispensable in the field of materials science. In the preparation of high-performance organic materials, 5-bromo-2-chloro-1,3-difluorobenzene can participate in the synthesis process of materials. By ingeniously designing the reaction path, it can be introduced into the polymer to improve the properties of the material, such as enhancing the heat resistance, chemical resistance, or even endowing the material with special optical or electrical properties, laying the foundation for the preparation of new electronic devices, optical materials, etc.
In addition, in the field of pesticide chemistry, it also plays an important role. Based on it, many highly efficient and low-toxic pesticides can be synthesized. Such pesticides may be highly selective to specific pests, capable of precisely killing pests, while minimizing the impact on the environment, and contributing to the sustainable development of agriculture. In conclusion, 5-bromo-2-chloro-1,3-difluorobenzene plays an important role in many fields such as medicine, materials, and pesticides due to its unique chemical properties, providing a key chemical basis for technological innovation and development in various fields.
What are the physical properties of 5-bromo-2-chloro-1,3-difluorobenzene?
5-Bromo-2-chloro-1,3-difluorobenzene is one of the organic compounds. Its physical properties are particularly important, and it is related to the properties and uses of this compound.
First of all, its appearance, under normal temperature and pressure, 5-bromo-2-chloro-1,3-difluorobenzene is often colorless to light yellow transparent liquid. The characteristics of this color state can be one of the aids in distinguishing this substance. Looking at its color and its shape, you can know its rough outline.
The second and boiling point are about 170-180 ° C. At the boiling point, the temperature limit for a substance to change from a liquid state to a gaseous state. At this temperature, the molecule of 5-bromo-2-chloro-1,3-difluorobenzene can escape from the liquid phase and rise into the gas phase. At this boiling point, it is very beneficial for distillation, separation and other processes.
In addition, the melting point is about -40 ° C. At the melting point, the substance melts from the solid state to the liquid state. This low temperature melting point makes it difficult for 5-bromo-2-chloro-1,3-difluorobenzene to be in a solid state at room temperature, and mostly exists in a liquid state.
The density of 5-bromo-2-chloro-1,3-difluorobenzene is about 1.8 g/cm ³. The density is also the mass of the substance per unit volume. This higher density, compared with common organic solvents, can cause it to settle in the mixed system, providing a basis for separation operations.
Solubility is also not negligible. It is insoluble in water, but it is well miscible in common organic solvents such as ethanol, ether, dichloromethane, etc. This solubility property provides a guide for the selection of suitable solvents in organic synthesis, so as to facilitate the progress of reactions and the separation of products.
In terms of volatility, although it is not very volatile, it can still evaporate slowly in an open environment and at an appropriate temperature. This volatility is related to boiling point, vapor pressure, etc. When operating, pay attention to ventilation to prevent it from accumulating in the air.
The physical properties of 5-bromo-2-chloro-1,3-difluorobenzene each have their own uses. The appearance can be intuitively identified. The melting point, density, solubility, volatility, etc. are of great guiding significance in the process design and operation control of chemical production and organic synthesis. Only by making good use of them can we obtain their benefits.
First of all, its appearance, under normal temperature and pressure, 5-bromo-2-chloro-1,3-difluorobenzene is often colorless to light yellow transparent liquid. The characteristics of this color state can be one of the aids in distinguishing this substance. Looking at its color and its shape, you can know its rough outline.
The second and boiling point are about 170-180 ° C. At the boiling point, the temperature limit for a substance to change from a liquid state to a gaseous state. At this temperature, the molecule of 5-bromo-2-chloro-1,3-difluorobenzene can escape from the liquid phase and rise into the gas phase. At this boiling point, it is very beneficial for distillation, separation and other processes.
In addition, the melting point is about -40 ° C. At the melting point, the substance melts from the solid state to the liquid state. This low temperature melting point makes it difficult for 5-bromo-2-chloro-1,3-difluorobenzene to be in a solid state at room temperature, and mostly exists in a liquid state.
The density of 5-bromo-2-chloro-1,3-difluorobenzene is about 1.8 g/cm ³. The density is also the mass of the substance per unit volume. This higher density, compared with common organic solvents, can cause it to settle in the mixed system, providing a basis for separation operations.
Solubility is also not negligible. It is insoluble in water, but it is well miscible in common organic solvents such as ethanol, ether, dichloromethane, etc. This solubility property provides a guide for the selection of suitable solvents in organic synthesis, so as to facilitate the progress of reactions and the separation of products.
In terms of volatility, although it is not very volatile, it can still evaporate slowly in an open environment and at an appropriate temperature. This volatility is related to boiling point, vapor pressure, etc. When operating, pay attention to ventilation to prevent it from accumulating in the air.
The physical properties of 5-bromo-2-chloro-1,3-difluorobenzene each have their own uses. The appearance can be intuitively identified. The melting point, density, solubility, volatility, etc. are of great guiding significance in the process design and operation control of chemical production and organic synthesis. Only by making good use of them can we obtain their benefits.
What are the synthesis methods of 5-bromo-2-chloro-1,3-difluorobenzene?
5-Bromo-2-chloro-1,3-difluorobenzene is also an organic compound. There are several ways to synthesize it.
First, halogenated aromatics are used as starting materials. First, appropriate aromatics are taken and brominated with a brominating agent. Liquid bromine can be used under the catalysis of iron or iron salts to replace hydrogen atoms at specific positions of aromatics to obtain aromatic hydrocarbon derivatives containing bromine. Subsequently, chlorination is applied with a chlorinating agent. For example, under the action of light or catalyst, chlorine atoms are substituted for hydrogen at a predetermined position to obtain compounds containing both bromine and chlorine. Finally, by means of fluorine-containing reagents, such as potassium fluoride, under suitable solvents and conditions, fluorine atoms are substituted for other atoms in the corresponding positions to achieve the purpose of introducing fluorine atoms, so as to obtain 5-bromo-2-chloro-1,3-difluorobenzene.
Second, fluoroaromatic hydrocarbons are used as the starting materials. First select fluorinated benzene compounds, and use halogenation reactions to introduce bromine atoms and chlorine atoms in turn. During bromination, according to the activity and positioning rules of aromatics, the appropriate bromination conditions can be selected to precisely make bromine atoms enter the desired position. The same is true for chlorination. According to different reaction conditions and catalysts, chlorine atoms are regulated to replace the check point and finally synthesize the target product.
Third, through multi-step functional group conversion. It can start from benzene derivatives containing other functional groups and gradually convert into compounds with functional groups such as bromine, chlorine and fluorine through a series of reactions. For example, first introduce transformable groups, such as nitro groups, etc., through reduction, diazotization and other reactions, it is converted into halogenated intermediates, and then undergo bromination, chlorination and fluorination reactions in sequence. The reaction sequence and conditions are carefully designed to obtain 5-bromo-2-chloro-1,3-difluorobenzene. All synthesis methods have their own advantages and disadvantages. In practical application, they should be selected according to factors such as the availability of raw materials, the difficulty of reaction conditions, and the high cost.
First, halogenated aromatics are used as starting materials. First, appropriate aromatics are taken and brominated with a brominating agent. Liquid bromine can be used under the catalysis of iron or iron salts to replace hydrogen atoms at specific positions of aromatics to obtain aromatic hydrocarbon derivatives containing bromine. Subsequently, chlorination is applied with a chlorinating agent. For example, under the action of light or catalyst, chlorine atoms are substituted for hydrogen at a predetermined position to obtain compounds containing both bromine and chlorine. Finally, by means of fluorine-containing reagents, such as potassium fluoride, under suitable solvents and conditions, fluorine atoms are substituted for other atoms in the corresponding positions to achieve the purpose of introducing fluorine atoms, so as to obtain 5-bromo-2-chloro-1,3-difluorobenzene.
Second, fluoroaromatic hydrocarbons are used as the starting materials. First select fluorinated benzene compounds, and use halogenation reactions to introduce bromine atoms and chlorine atoms in turn. During bromination, according to the activity and positioning rules of aromatics, the appropriate bromination conditions can be selected to precisely make bromine atoms enter the desired position. The same is true for chlorination. According to different reaction conditions and catalysts, chlorine atoms are regulated to replace the check point and finally synthesize the target product.
Third, through multi-step functional group conversion. It can start from benzene derivatives containing other functional groups and gradually convert into compounds with functional groups such as bromine, chlorine and fluorine through a series of reactions. For example, first introduce transformable groups, such as nitro groups, etc., through reduction, diazotization and other reactions, it is converted into halogenated intermediates, and then undergo bromination, chlorination and fluorination reactions in sequence. The reaction sequence and conditions are carefully designed to obtain 5-bromo-2-chloro-1,3-difluorobenzene. All synthesis methods have their own advantages and disadvantages. In practical application, they should be selected according to factors such as the availability of raw materials, the difficulty of reaction conditions, and the high cost.
What are the precautions for 5-bromo-2-chloro-1,3-difluorobenzene in storage and transportation?
5-Bromo-2-chloro-1,3-difluorobenzene is also an organic compound. During storage and transportation, there are several ends that should be paid attention to.
First words storage, this compound should be placed in a cool and well ventilated place. Cover its properties or change due to excessive temperature, causing danger. If it is exposed to high temperature, or cause its chemical reaction, damage its quality, or even risk of explosion. And should be kept away from fire and heat sources. Open flames and high temperatures are the beginning of disaster, and a little carelessness will lead to disaster.
Also, it must be stored in isolation from oxidants, acids, bases, etc. Because of its chemical activity, it is easy to meet with their substances and cause chemical reactions. If it coexists with oxidants, or triggers a violent oxidation reaction, it will cause a hot topic and cause a fire.
The storage place should also be equipped with suitable materials to contain leaks. Just in case of leakage, it can be collected in time to prevent its spread, pollute the environment and endanger all living beings.
As for transportation, it must be handled lightly. Because it is a fine chemical, rough handling may cause package damage and compound leakage. If the package is damaged, not only will the material be lost, but the leaked material may endanger the safety of transporters and pollute the surrounding environment.
Vehicles used for transportation should also ensure that they are clean, dry and free of other chemical residues. Otherwise, the residual material interacts with 5-bromo-2-chloro-1,3-difluorobenzene, or has an unpredictable reaction.
During transportation, close monitoring of temperature and humidity is required. Abnormal temperature and humidity can affect the stability of the compound. A suitable temperature and humidity environment can ensure its safety during transportation.
In summary, 5-bromo-2-chloro-1,3-difluorobenzene is important in storage and transportation. If it is slightly sparse, it will cause disasters, so it should be treated with caution.
First words storage, this compound should be placed in a cool and well ventilated place. Cover its properties or change due to excessive temperature, causing danger. If it is exposed to high temperature, or cause its chemical reaction, damage its quality, or even risk of explosion. And should be kept away from fire and heat sources. Open flames and high temperatures are the beginning of disaster, and a little carelessness will lead to disaster.
Also, it must be stored in isolation from oxidants, acids, bases, etc. Because of its chemical activity, it is easy to meet with their substances and cause chemical reactions. If it coexists with oxidants, or triggers a violent oxidation reaction, it will cause a hot topic and cause a fire.
The storage place should also be equipped with suitable materials to contain leaks. Just in case of leakage, it can be collected in time to prevent its spread, pollute the environment and endanger all living beings.
As for transportation, it must be handled lightly. Because it is a fine chemical, rough handling may cause package damage and compound leakage. If the package is damaged, not only will the material be lost, but the leaked material may endanger the safety of transporters and pollute the surrounding environment.
Vehicles used for transportation should also ensure that they are clean, dry and free of other chemical residues. Otherwise, the residual material interacts with 5-bromo-2-chloro-1,3-difluorobenzene, or has an unpredictable reaction.
During transportation, close monitoring of temperature and humidity is required. Abnormal temperature and humidity can affect the stability of the compound. A suitable temperature and humidity environment can ensure its safety during transportation.
In summary, 5-bromo-2-chloro-1,3-difluorobenzene is important in storage and transportation. If it is slightly sparse, it will cause disasters, so it should be treated with caution.
What are the effects of 5-bromo-2-chloro-1,3-difluorobenzene on the environment and human health?
5-Bromo-2-chloro-1,3-difluorobenzene is also an organic compound. The impact of this substance on the environment and human health can be particularly investigated.
In the environment, it may be quite stable and not easy to degrade quickly. If released in nature, it may be retained in soil and water bodies. Entering the soil, or causing soil pollution, prevents plant roots from absorbing nutrients and water, thereby damaging plant growth and disrupting ecological balance. If it flows into water bodies, or is ingested by aquatic organisms, it will be enriched through the food chain, harming many aquatic organisms. If small fish ingest plankton containing this compound, and large fish re-eat small fish, the concentration in large fish will gradually increase, endangering fish populations and affecting birds and other organisms that depend on aquatic organisms for food.
As for personal health, it can be dangerous through respiratory, skin contact or dietary intake. Entering the body through the respiratory tract, or irritating the mucosa of the respiratory tract, causing cough, asthma and other diseases. If the skin is often touched, it may cause allergies and inflammation. Enter the digestive system, or damage the liver, kidneys and other organs. Because of its halogen atoms, or participate in chemical reactions in the body, it interferes with the normal metabolism and physiological functions of cells. And this substance may be potentially carcinogenic, long-term exposure increases the risk of cancer.
In conclusion, 5-bromo-2-chloro-1,3-difluorobenzene has potential hazards to the environment and human health, and it should be handled with caution to prevent its escape from causing damage to the environment and human body.
In the environment, it may be quite stable and not easy to degrade quickly. If released in nature, it may be retained in soil and water bodies. Entering the soil, or causing soil pollution, prevents plant roots from absorbing nutrients and water, thereby damaging plant growth and disrupting ecological balance. If it flows into water bodies, or is ingested by aquatic organisms, it will be enriched through the food chain, harming many aquatic organisms. If small fish ingest plankton containing this compound, and large fish re-eat small fish, the concentration in large fish will gradually increase, endangering fish populations and affecting birds and other organisms that depend on aquatic organisms for food.
As for personal health, it can be dangerous through respiratory, skin contact or dietary intake. Entering the body through the respiratory tract, or irritating the mucosa of the respiratory tract, causing cough, asthma and other diseases. If the skin is often touched, it may cause allergies and inflammation. Enter the digestive system, or damage the liver, kidneys and other organs. Because of its halogen atoms, or participate in chemical reactions in the body, it interferes with the normal metabolism and physiological functions of cells. And this substance may be potentially carcinogenic, long-term exposure increases the risk of cancer.
In conclusion, 5-bromo-2-chloro-1,3-difluorobenzene has potential hazards to the environment and human health, and it should be handled with caution to prevent its escape from causing damage to the environment and human body.
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