Linshang Chemical
PRODUCTS
5-Bromo-2-Chloro-Benzenetrifluoride
Linshang Chemical
|
HS Code |
430718 |
| Chemical Formula | C6H2BrClF3 |
| Molar Mass | 259.43 g/mol |
| Appearance | colorless to light yellow liquid |
| Boiling Point | 187 - 188 °C |
| Density | 1.739 g/cm³ |
| Water Solubility | Insoluble |
| Flash Point | 77 °C |
| Refractive Index | 1.468 |
As an accredited 5-Bromo-2-Chloro-Benzenetrifluoride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 5 - bromo - 2 - chloro - benzenetrifluoride in 1 - kg sealed containers for secure storage. |
| Storage | Store 5 - bromo - 2 - chloro - benzenetrifluoride in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Avoid storing it near oxidizing agents or reactive substances. Clearly label the storage container with relevant safety and identification information. |
| Shipping | 5 - bromo - 2 - chloro - benzenetrifluoride is a chemical. Shipping should follow strict hazardous material regulations. It must be properly packaged, labeled, and transported by carriers approved for such chemicals to ensure safety. |
Competitive 5-Bromo-2-Chloro-Benzenetrifluoride prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a trusted 5-Bromo-2-Chloro-Benzenetrifluoride manufacturer, we deliver:
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 5-Bromo-2-Chloro-Benzenetrifluoride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 5-bromo-2-chlorotrifluorotoluene?
5-% ether-2-chlorotrifluoroethane, its physical properties are as follows:
This substance is a colorless gas at room temperature and pressure, with a faint ether smell. The boiling point is about -26.5 ° C. At this temperature, it changes from liquid to gaseous state and is easy to volatilize. This property makes it crucial in some refrigeration, foaming and other application scenarios, because it can quickly achieve phase transformation to achieve corresponding functions. The melting point is about -103 ° C. It is solid at low temperature, showing good low temperature stability. In extremely low temperature environments, it can still maintain its own structure and properties stable, and will not easily deteriorate or deform due to low temperature.
In terms of density, the relative air density in the gaseous state is about 3.6 (air = 1). Because its density is higher than that of air, if it leaks in an open environment, the gas will gather close to the ground, and it is necessary to pay attention to ventilation to prevent danger. The density of the liquid state is about 1.32 g/cm ³, which is different from the density of common organic solvents. This value is of great significance for the design of processes involving liquid transport, storage, and distribution in mixed systems.
In terms of solubility, it is slightly soluble in water, but can be miscible with most organic solvents, such as alcohols, ethers, hydrocarbons, etc. Good solubility in organic solvents makes it suitable for use as a solvent or co-solvent in the fields of organic synthesis, coatings, cleaning, etc., to help various chemical reactions proceed smoothly, or to dissolve specific substances for separation and purification purposes.
In addition, 5-% ether-2-chlorotrifluoroethane also has non-flammability, relatively stable chemical properties, and is not easy to chemically react with common substances. These characteristics make it safe in many industrial and civil applications, without excessive worry about fire, explosion, and violent reactions with other substances.
This substance is a colorless gas at room temperature and pressure, with a faint ether smell. The boiling point is about -26.5 ° C. At this temperature, it changes from liquid to gaseous state and is easy to volatilize. This property makes it crucial in some refrigeration, foaming and other application scenarios, because it can quickly achieve phase transformation to achieve corresponding functions. The melting point is about -103 ° C. It is solid at low temperature, showing good low temperature stability. In extremely low temperature environments, it can still maintain its own structure and properties stable, and will not easily deteriorate or deform due to low temperature.
In terms of density, the relative air density in the gaseous state is about 3.6 (air = 1). Because its density is higher than that of air, if it leaks in an open environment, the gas will gather close to the ground, and it is necessary to pay attention to ventilation to prevent danger. The density of the liquid state is about 1.32 g/cm ³, which is different from the density of common organic solvents. This value is of great significance for the design of processes involving liquid transport, storage, and distribution in mixed systems.
In terms of solubility, it is slightly soluble in water, but can be miscible with most organic solvents, such as alcohols, ethers, hydrocarbons, etc. Good solubility in organic solvents makes it suitable for use as a solvent or co-solvent in the fields of organic synthesis, coatings, cleaning, etc., to help various chemical reactions proceed smoothly, or to dissolve specific substances for separation and purification purposes.
In addition, 5-% ether-2-chlorotrifluoroethane also has non-flammability, relatively stable chemical properties, and is not easy to chemically react with common substances. These characteristics make it safe in many industrial and civil applications, without excessive worry about fire, explosion, and violent reactions with other substances.
What are the chemical properties of 5-bromo-2-chlorotrifluorotoluene?
5-Hydroxy-2-mercaptotriacetamide is an organic compound with multiple unique chemical properties.
It is weakly acidic because both hydroxyl and mercapto groups in the molecule can ionize hydrogen ions. However, the degree of ionization is quite small and the acidity is weak. In aqueous solution, it can neutralize with bases to form corresponding salts.
5-Hydroxy-2-mercaptotriacetamide contains active groups such as hydroxyl groups, mercapto groups and amide groups, so its chemical activity is quite high. Hydroxyl groups can participate in esterification reactions. Under acid-catalyzed conditions, they combine with acyl groups of organic acids or inorganic acids to form ester compounds.
Mercapto groups are also highly active and easy to be oxidized. In case of mild oxidants, disulfide bonds can be formed; in case of strong oxidants, it can even be oxidized to sulfonic acid groups. And thiol groups can coordinate with metal ions to form stable complexes, which is of great application value in the detection and separation of metal ions.
Amide groups can undergo hydrolysis under acid or base catalysis. Under acidic conditions, carboxylic acids and ammonium salts are hydrolyzed; under basic conditions, carboxylic salts and ammonia or amines are hydrolyzed.
The compound still has a certain coordination ability, and can form coordination compounds with various metal ions by virtue of the coordination atoms such as nitrogen, oxygen, and sulfur it contains. This coordination ability is of great significance in the fields of materials science, catalytic chemistry, etc. It can be used to prepare complex materials with specific structures and properties, or used as ligands in catalytic reactions to improve catalyst activity and selectivity.
In summary, the weak acidity, reactivity and coordination ability of 5-hydroxyl-2-mercaptotriacetamide have potential applications in many fields such as organic synthesis, pharmaceutical chemistry, and materials science.
It is weakly acidic because both hydroxyl and mercapto groups in the molecule can ionize hydrogen ions. However, the degree of ionization is quite small and the acidity is weak. In aqueous solution, it can neutralize with bases to form corresponding salts.
5-Hydroxy-2-mercaptotriacetamide contains active groups such as hydroxyl groups, mercapto groups and amide groups, so its chemical activity is quite high. Hydroxyl groups can participate in esterification reactions. Under acid-catalyzed conditions, they combine with acyl groups of organic acids or inorganic acids to form ester compounds.
Mercapto groups are also highly active and easy to be oxidized. In case of mild oxidants, disulfide bonds can be formed; in case of strong oxidants, it can even be oxidized to sulfonic acid groups. And thiol groups can coordinate with metal ions to form stable complexes, which is of great application value in the detection and separation of metal ions.
Amide groups can undergo hydrolysis under acid or base catalysis. Under acidic conditions, carboxylic acids and ammonium salts are hydrolyzed; under basic conditions, carboxylic salts and ammonia or amines are hydrolyzed.
The compound still has a certain coordination ability, and can form coordination compounds with various metal ions by virtue of the coordination atoms such as nitrogen, oxygen, and sulfur it contains. This coordination ability is of great significance in the fields of materials science, catalytic chemistry, etc. It can be used to prepare complex materials with specific structures and properties, or used as ligands in catalytic reactions to improve catalyst activity and selectivity.
In summary, the weak acidity, reactivity and coordination ability of 5-hydroxyl-2-mercaptotriacetamide have potential applications in many fields such as organic synthesis, pharmaceutical chemistry, and materials science.
What are the main uses of 5-bromo-2-chlorotrifluorotoluene?
5-% arsine-2-chlorotrifluoroethane, its main uses are as follows:
This substance has significant uses in the field of refrigeration. In the past, it was often used as a refrigerant and filled in refrigerators, air conditioners and other refrigeration equipment. Because of its suitable boiling point and latent heat of vaporization, it can efficiently transfer heat in the refrigeration cycle. By changing its own state, it absorbs heat in the evaporator and vaporizes, and releases heat in the condenser to liquefy. This reciprocates to achieve the purpose of refrigeration.
In the production of foam plastics and other materials, 5-% arsine-2-chlorotrifluoroethane can be added to the system as a blowing agent. During processing, it is heated and vaporized to produce gases, which form many tiny bubbles inside the material, so that the material has a porous foam structure, which can be used to make various foam materials such as polyurethane foam, giving the material good thermal insulation, buffering and other properties.
However, it should be noted that with the deepening of environmental and health awareness, some arsenic-containing and chlorofluorocarbon compounds are subject to many restrictions due to their destructive effects on the ozone layer or certain toxicity. People continue to develop more environmentally friendly and safe alternative substances to meet the needs of industrial production and life while reducing the adverse effects on the ecological environment and human health.
This substance has significant uses in the field of refrigeration. In the past, it was often used as a refrigerant and filled in refrigerators, air conditioners and other refrigeration equipment. Because of its suitable boiling point and latent heat of vaporization, it can efficiently transfer heat in the refrigeration cycle. By changing its own state, it absorbs heat in the evaporator and vaporizes, and releases heat in the condenser to liquefy. This reciprocates to achieve the purpose of refrigeration.
In the production of foam plastics and other materials, 5-% arsine-2-chlorotrifluoroethane can be added to the system as a blowing agent. During processing, it is heated and vaporized to produce gases, which form many tiny bubbles inside the material, so that the material has a porous foam structure, which can be used to make various foam materials such as polyurethane foam, giving the material good thermal insulation, buffering and other properties.
However, it should be noted that with the deepening of environmental and health awareness, some arsenic-containing and chlorofluorocarbon compounds are subject to many restrictions due to their destructive effects on the ozone layer or certain toxicity. People continue to develop more environmentally friendly and safe alternative substances to meet the needs of industrial production and life while reducing the adverse effects on the ecological environment and human health.
What are the synthesis methods of 5-bromo-2-chlorotrifluorotoluene?
The synthesis of 5-bromo-2-chlorotrifluorotoluene has always been an important task in organic synthesis. There are many methods, each with its advantages and disadvantages, which are described in detail below.
First, halogenation method. Using appropriate aromatic compounds as starting materials, bromine and chlorine atoms are introduced through halogenation reaction. First select toluene derivatives, and under specific reaction conditions, use brominating agents and chlorinating agents to act separately. During bromination, liquid bromine and initiators, such as benzoyl peroxide, are used to selectively replace hydrogen atoms at specific positions in the benzene ring under heating or light conditions. After chlorination, chlorine gas or sulfoxide chloride can be selected as the chlorinating agent. The reaction conditions are precisely regulated according to the activity of the reaction substrate and the desired product structure to achieve the introduction of chlorine atoms. This process requires fine control of reaction temperature, time and reagent dosage to achieve ideal regional selectivity and yield.
Second, fluorination method. If aromatic hydrocarbons containing bromine and chlorine are available, trifluoromethyl can be introduced through fluorination reaction. Commonly used fluorination reagents are trifluoromethylation reagents, such as sodium trifluoromethylsulfonate. In the presence of appropriate organic solvents and bases, nucleophilic substitution reactions occur. In the reaction, the selection of bases is crucial. According to the activity of the substrate and the characteristics of the reaction system, the base with appropriate strength should be selected to promote the smooth progress of the fluorination reaction and avoid side reactions. The key to this method is to optimize the reaction conditions and improve the efficiency and selectivity of trifluoromethylation.
Third, the cross-coupling method. Using aromatic hydrocarbon halides containing bromine and chlorine and trifluoromethylation reagents as raw materials, the goal is achieved by cross-coupling reactions catalyzed by transition metals. Commonly used transition metal catalysts include palladium, nickel, etc. In the reaction, the catalyst and the ligand work synergistically to activate the substrate molecule, promoting the cracking of carbon-halogen bonds and the formation of carbon-trifluoromethyl bonds. The structure of the ligand has a significant impact on the reactivity and selectivity, so careful screening is required. At the same time, the reaction solvent, base and reaction temperature conditions are optimized to improve the efficiency and yield of the reaction.
In short, the synthesis of 5-bromo-2-chlorotrifluorotoluene requires considering the advantages and disadvantages of each method according to the actual situation, choosing the synthesis path reasonably, and optimizing the reaction conditions in order to obtain the target product efficiently.
First, halogenation method. Using appropriate aromatic compounds as starting materials, bromine and chlorine atoms are introduced through halogenation reaction. First select toluene derivatives, and under specific reaction conditions, use brominating agents and chlorinating agents to act separately. During bromination, liquid bromine and initiators, such as benzoyl peroxide, are used to selectively replace hydrogen atoms at specific positions in the benzene ring under heating or light conditions. After chlorination, chlorine gas or sulfoxide chloride can be selected as the chlorinating agent. The reaction conditions are precisely regulated according to the activity of the reaction substrate and the desired product structure to achieve the introduction of chlorine atoms. This process requires fine control of reaction temperature, time and reagent dosage to achieve ideal regional selectivity and yield.
Second, fluorination method. If aromatic hydrocarbons containing bromine and chlorine are available, trifluoromethyl can be introduced through fluorination reaction. Commonly used fluorination reagents are trifluoromethylation reagents, such as sodium trifluoromethylsulfonate. In the presence of appropriate organic solvents and bases, nucleophilic substitution reactions occur. In the reaction, the selection of bases is crucial. According to the activity of the substrate and the characteristics of the reaction system, the base with appropriate strength should be selected to promote the smooth progress of the fluorination reaction and avoid side reactions. The key to this method is to optimize the reaction conditions and improve the efficiency and selectivity of trifluoromethylation.
Third, the cross-coupling method. Using aromatic hydrocarbon halides containing bromine and chlorine and trifluoromethylation reagents as raw materials, the goal is achieved by cross-coupling reactions catalyzed by transition metals. Commonly used transition metal catalysts include palladium, nickel, etc. In the reaction, the catalyst and the ligand work synergistically to activate the substrate molecule, promoting the cracking of carbon-halogen bonds and the formation of carbon-trifluoromethyl bonds. The structure of the ligand has a significant impact on the reactivity and selectivity, so careful screening is required. At the same time, the reaction solvent, base and reaction temperature conditions are optimized to improve the efficiency and yield of the reaction.
In short, the synthesis of 5-bromo-2-chlorotrifluorotoluene requires considering the advantages and disadvantages of each method according to the actual situation, choosing the synthesis path reasonably, and optimizing the reaction conditions in order to obtain the target product efficiently.
What are the precautions for storing and transporting 5-bromo-2-chlorotrifluorotoluene?
5-% -2-alkyltrifluoroacetonitrile should be carefully stored in the warehouse. This is because of its special nature, a little carelessness, or cause disease, so caution is required.
The first word to hide is that it must be dry, and it must be good. If it is in a place where the tide is, it is easy to hydrolyze and cause it to be bad. And the degree should be controlled, not high, because high temperature can promote its transformation and reaction, or cause no worry. In addition, the hidden utensils should be dense to prevent exposure. Such things are not in the air, or other things are in contact, and it is feared that they will be damaged.
When it comes to the warehouse, it is also necessary to pay attention. The equipment must be kept confidential and in good condition, and the road should be carefully protected against shocks and collisions. The shock may cause the container to break, and it will leak out. It is necessary to avoid open flames and high-temperature environments, because it may be flammable and explosive. And people need to be well-versed, familiar with the characteristics of this object and urgent methods. As soon as there is a problem, they can be installed immediately to avoid damage.
In addition, if they do not hide or hide, they must comply with the regulations, such as the amount and flow direction of the information. Those who are connected to it also need to use anti-damage equipment, such as anti-wear, gloves, and masks, to ensure their own safety. In addition, the storage of 5-% -2-alkyltrifluoroacetonitrile must be comprehensive, and there should be no slack to ensure safety.
The first word to hide is that it must be dry, and it must be good. If it is in a place where the tide is, it is easy to hydrolyze and cause it to be bad. And the degree should be controlled, not high, because high temperature can promote its transformation and reaction, or cause no worry. In addition, the hidden utensils should be dense to prevent exposure. Such things are not in the air, or other things are in contact, and it is feared that they will be damaged.
When it comes to the warehouse, it is also necessary to pay attention. The equipment must be kept confidential and in good condition, and the road should be carefully protected against shocks and collisions. The shock may cause the container to break, and it will leak out. It is necessary to avoid open flames and high-temperature environments, because it may be flammable and explosive. And people need to be well-versed, familiar with the characteristics of this object and urgent methods. As soon as there is a problem, they can be installed immediately to avoid damage.
In addition, if they do not hide or hide, they must comply with the regulations, such as the amount and flow direction of the information. Those who are connected to it also need to use anti-damage equipment, such as anti-wear, gloves, and masks, to ensure their own safety. In addition, the storage of 5-% -2-alkyltrifluoroacetonitrile must be comprehensive, and there should be no slack to ensure safety.
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